Glioblastoma-synthesized G-CSF and GM-CSF contribute to growth and immunosuppression: Potential therapeutic benefit from dapsone, fenofibrate, and ribavirin von Kast, Richard E, Hill, Quentin A, Wion, Didier, Mellstedt, Håkan, Focosi, Daniele, Karpel-Massler, Georg, Heiland, Tim, Halatsch, Marc-Eric

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In Vitro and Clinical Compassionate Use Experiences with the Drug-Repurposing Approach CUSP9v3 in Glioblastoma von Halatsch, Marc-Eric, Dwucet, Annika, Schmidt, Carl Julius, Muhlnickel, Julius, Heiland, Tim, Zeiler, Katharina, Siegelin, Markus D., Kast, Richard Eric, Karpel-Massler, Georg

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A New Treatment Opportunity for DIPG and Diffuse Midline Gliomas: 5-ALA Augmented Irradiation, the 5aai Regimen von Kast, Richard E., Michael, Alex P., Sardi, Iacopo, Burns, Terry C., Heiland, Tim, Karpel-Massler, Georg, Kamar, Francois G., Halatsch, Marc-Eric

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A New Experimental Polytrauma Model in Rats: Molecular Characterization of the Early Inflammatory Response von Huber-Lang, Markus S., Gebhard, F., Flierl, Michael A., Stahel, Philip F., Braumüller, Sonja, Heiland, Tim, Perl, Mario, Weckbach, Sebastian, Ignatius, Anita

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Globus Lucidus: A porcine study of an intracranial implant designed to deliver closed, repetitive photodynamic and photochemical therapy in glioblastoma von Bader, Nicolas, Peschmann, Christian, Kast, Richard Eric, Heiland, Tim, Merz, Tamara, McCook, Oscar, Alfieri, Alex, Karpel-Massler, Georg, Capanni, Felix, Halatsch, Marc-Eric

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Bcl‐2/Bcl‐xL inhibition predominantly synergistically enhances the anti‐neoplastic activity of a low‐dose CUSP9 repurposed drug regime against glioblastoma von Halatsch, Marc‐Eric, Kast, Richard Eric, Dwucet, Annika, Hlavac, Michal, Heiland, Tim, Westhoff, Mike‐Andrew, Debatin, Klaus‐Michael, Wirtz, Christian Rainer, Siegelin, Markus David, Karpel‐Massler, Georg

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EXTH-45. THE REPURPOSED CUSP9 REGIMEN EXERTS POTENT ANTI-NEOPLASTIC ACTIVITY AGAINST GLIOBLASTOMA CELLS IN VITRO von Halatsch, Marc-Eric, Kast, Richard Eric, Dwucet, Annika, Siegelin, Markus, Heiland, Tim, Karpel-Massler, Georg

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Rare Case of Sporadic Malignant Optic Pathway Glioma in 71-Year-Old Woman von Heiland, Tim, Karpel-Massler, Georg, Scheuerle, Angelika, Wirtz, Christian-Rainer, Halatsch, Marc-Eric

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ACTR-44. PRELIMINARY RESULTS FROM THE NCT02770378 PROOF-OF-CONCEPT CLINICAL TRIAL ASSESSING THE SAFETY OF THE CUSP9v3 PROTOCOL COMBINED WITH METRONOMIC TEMOZOLOMIDE FOR RECURRENT G... von Halatsch, Marc-Eric, Kast, Richard, Karpel-Massler, Georg, Schmidt, Carl, Schmelzle, Birgit, Awad, Fadi, Panther, Patricia, Heiland, Tim

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A phase Ib/IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma: CUSP9v3 von Halatsch, Marc-Eric, Kast, Richard E, Karpel-Massler, Georg, Mayer, Benjamin, Zolk, Oliver, Schmitz, Bernd, Scheuerle, Angelika, Maier, Ludwig, Bullinger, Lars, Mayer-Steinacker, Regine, Schmidt, Carl, Zeiler, Katharina, Elshaer, Ziad, Panther, Patricia, Schmelzle, Birgit, Hallmen, Anke, Dwucet, Annika, Siegelin, Markus D, Westhoff, Mike-Andrew, Beckers, Kristine, Bouche, Gauthier, Heiland, Tim

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CTNI-04. RECURRENT GLIOBLASTOMA LONG-TERM SURVIVORS TREATED WITH CUSP9v3 von Halatsch, Marc-Eric, Kast, Richard, Karpel-Massler, Georg, Mayer, Benjamin, Zolk, Oliver, Schmitz, Bernd, Scheuerle, Angelika, Maier, Ludwig, Bullinger, Lars, Mayer-Steinacker, Regine, Schmidt, Carl, Zeiler, Katharina, Elshaer, Ziad, Panther, Patricia, Schmelzle, Birgit, Hallmen, Anke, Dwucet, Annika, Siegelin, Markus D, Westhoff, Mike-Andrew, Beckers, Kristine, Bouche, Gauthier, Heiland, Tim

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Photodynamic Therapy Combined with Bcl-2/Bcl-xL Inhibition Increases the Noxa/Mcl-1 Ratio Independent of Usp9X and Synergistically Enhances Apoptosis in Glioblastoma von Golla, Carolin, Bilal, Mayas, Dwucet, Annika, Bader, Nicolas, Anthonymuthu, Jenson, Heiland, Tim, Pruss, Maximilian, Westhoff, Mike-Andrew, Siegelin, Markus David, Capanni, Felix, Wirtz, Christian Rainer, Kast, Richard Eric, Halatsch, Marc-Eric, Karpel-Massler, Georg

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Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas von Friedrich, Mirco, Sankowski, Roman, Bunse, Lukas, Kilian, Michael, Green, Edward, Guevara, Carina Ramallo, Pusch, Stefan, Poschet, Gernot, Sanghvi, Khwab, Hahn, Markus, Bunse, Theresa, Muench, Philipp, Gegner, Hagen M., Sonner, Jana K., von Landenberg, Anna, Cichon, Frederik, Aslan, Katrin, Trobisch, Tim, Schirmer, Lucas, Abu-Sammour, Denis, Kessler, Tobias, Ratliff, Miriam, Schrimpf, Daniel, Sahm, Felix, Hopf, Carsten, Heiland, Dieter H., Schnell, Oliver, Beck, Jurgen, Boettcher, Chotima, Fernandez-Zapata, Camila, Priller, Josef, Heiland, Sabine, Gutcher, Ilona, Quintana, Francisco J., von Deimling, Andreas, Wick, Wolfgang, Prinz, Marco, Platten, Michael

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In vivo comparison of MRI- and CBCT-based 3D cephalometric analysis: beginning of a non-ionizing diagnostic era in craniomaxillofacial imaging? von Juerchott, Alexander, Freudlsperger, Christian, Weber, Dorothea, Jende, Johann M. E., Saleem, Muhammad Abdullah, Zingler, Sebastian, Lux, Christopher J., Bendszus, Martin, Heiland, Sabine, Hilgenfeld, Tim

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Use of dental MRI for radiation-free guided dental implant planning: a prospective, in vivo study of accuracy and reliability von Hilgenfeld, Tim, Juerchott, Alexander, Jende, Johann M. E., Rammelsberg, Peter, Heiland, Sabine, Bendszus, Martin, Schwindling, Franz S.

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Neuromodulation of chronic headaches: position statement from the European Headache Federation von Martelletti, Paolo, Jensen, Rigmor H, Antal, Andrea, Arcioni, Roberto, Brighina, Filippo, de Tommaso, Marina, Franzini, Angelo, Fontaine, Denys, Heiland, Max, Jürgens, Tim P, Leone, Massimo, Magis, Delphine, Paemeleire, Koen, Palmisani, Stefano, Paulus, Walter, May, Arne

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Diffusion MRI in Peripheral Nerves: Optimized b Values and the Role of Non-Gaussian Diffusion von Foesleitner, Olivia, Sulaj, Alba, Sturm, Volker, Kronlage, Moritz, Godel, Tim, Preisner, Fabian, Nawroth, Peter Paul, Bendszus, Martin, Heiland, Sabine, Schwarz, Daniel

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Lateral cephalometric analysis for treatment planning in orthodontics based on MRI compared with radiographs: A feasibility study in children and adolescents von Heil, Alexander, Lazo Gonzalez, Eduardo, Hilgenfeld, Tim, Kickingereder, Philipp, Bendszus, Martin, Heiland, Sabine, Ozga, Ann-Kathrin, Sommer, Andreas, Lux, Christopher J, Zingler, Sebastian

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Differentiation of periapical granulomas and cysts by using dental MRI: a pilot study von Juerchott, Alexander, Pfefferle, Thorsten, Flechtenmacher, Christa, Mente, Johannes, Bendszus, Martin, Heiland, Sabine, Hilgenfeld, Tim

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Accuracy of cone‐beam computed tomography, dental magnetic resonance imaging, and intraoral radiography for detecting peri‐implant bone defects at single zirconia implants—An in vi... von Hilgenfeld, Tim, Juerchott, Alexander, Deisenhofer, Ulrich Karl, Krisam, Johannes, Rammelsberg, Peter, Heiland, Sabine, Bendszus, Martin, Schwindling, Franz Sebastian

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