Discovery of ZN-c3, a Highly Potent and Selective Wee1 Inhibitor Undergoing Evaluation in Clinical Trials for the Treatment of Cancer von Huang, Peter Q, Boren, Brant C, Hegde, Sayee G, Liu, Hui, Unni, Aditya K, Abraham, Sunny, Hopkins, Chad D, Paliwal, Sunil, Samatar, Ahmed A, Li, Jiali, Bunker, Kevin D

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Structure-based optimization of aminothiadiazole inhibitors of AKT von Mortensen, Deborah S., Hegde, Sayee G., Perrin-Ninkovic, Sophie M., Bahmanyar, Sogole, McCarrick, Meg, Harris, Roy, Hilgraf, Robert, Lee, Branden G. S., McKie, Jeff, Nadolny, Lisa, Sapienza, John, Collette, Alice, Cox, Sarah, Gamez, James C., Hensel, Jennifer L., Hua, Xuequn Helen, Leisten, Jim, Raymon, Heather K., Tran, Tam, Narla, Rama Krishna

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Abstract 2606: ZN-c3, a potent and selective Wee-1 inhibitor demonstrates anti-tumor activities in combination with other targeted therapies and overcomes PARP inhibitor resistance von Li, Jiali, Ma, Jianhui, de Jong, Petrus R., Izadi, Hooman, Hoang, Tiffany, Ibrahim, Noah, Boren, Brant, Hegde, Sayee Hegde, Doñate, Fernando, Samatar, Ahmed A.

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Microtubule-Stabilizing Agents Based on Designed Laulimalide Analogues von Mooberry, Susan L., Randall-Hlubek, Deborah A., Leal, Rachel M., Hegde, Sayee G., Hubbard, Robert D., Zhang, Lei, Wender, Paul A.

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Total Synthesis of (−)-Laulimalide von Wender, Paul A, Hegde, Sayee G, Hubbard, Robert D, Zhang, Lei

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Synthesis and Biological Evaluation of (−)-Laulimalide Analogues von Wender, Paul A, Hegde, Sayee G, Hubbard, Robert D, Zhang, Lei, Mooberry, Susan L

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Abstract 4373: Discovery of ZN-c5, a novel potent and oral selective estrogen receptor degrader von Samatar, Ahmed A., Li, Jiali, Hegde, Sayee, Huang, Peter, Ma, Jianhui, Bunker, Kevin, Winkler, Robert, Donate, Fernando, Sergeeva, Masha

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Correction to “Discovery of the Selective Protein Kinase C‑θ Kinase Inhibitor, CC-90005” von Papa, Patrick, Whitefield, Brandon, Mortensen, Deborah S., Cashion, Dan, Huang, Dehua, Torres, Eduardo, Parnes, Jason, Sapienza, John, Hansen, Joshua, Correa, Matthew, Delgado, Mercedes, Harris, Roy, Hegde, Sayee, Norris, Stephen, Bahmanyar, Sogole, Plantevin-Krenitsky, Veronique, Liu, Zheng, Leftheris, Katerina, Kulkarni, Ashutosh, Bennett, Brydon, Hur, Eun Mi, Ringheim, Garth, Khambatta, Godrej, Chan, Henry, Muir, Jeffrey, Blease, Kate, Burnett, Kelven, LeBrun, Laurie, Morrison, Lisa, Celeridad, Maria, Khattri, Roli, Cathers, Brian E.

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Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005 von Papa, Patrick, Whitefield, Brandon, Mortensen, Deborah S, Cashion, Dan, Huang, Dehua, Torres, Eduardo, Parnes, Jason, Sapienza, John, Hansen, Joshua, Correa, Matthew, Delgado, Mercedes, Harris, Roy, Hegde, Sayee, Norris, Stephen, Bahmanyar, Sogole, Plantevin-Krenitsky, Veronique, Liu, Zheng, Leftheris, Katerina, Kulkarni, Ashutosh, Bennett, Brydon, Hur, Eun Mi, Ringheim, Garth, Khambatta, Godrej, Chan, Henry, Muir, Jeffrey, Blease, Kate, Burnett, Kelven, LeBrun, Laurie, Morrison, Lisa, Celeridad, Maria, Khattri, Roli, Cathers, Brian E

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Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor von Plantevin Krenitsky, Véronique, Nadolny, Lisa, Delgado, Mercedes, Ayala, Leticia, Clareen, Steven S., Hilgraf, Robert, Albers, Ronald, Hegde, Sayee, D’Sidocky, Neil, Sapienza, John, Wright, Jonathan, McCarrick, Meg, Bahmanyar, Sogole, Chamberlain, Philip, Delker, Silvia L., Muir, Jeff, Giegel, David, Xu, Li, Celeridad, Maria, Lachowitzer, Jeff, Bennett, Brydon, Moghaddam, Mehran, Khatsenko, Oleg, Katz, Jason, Fan, Rachel, Bai, April, Tang, Yang, Shirley, Michael A., Benish, Brent, Bodine, Tracey, Blease, Kate, Raymon, Heather, Cathers, Brian E., Satoh, Yoshitaka

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ESTROGEN RECEPTOR MODULATORS von BUNKER, Kevin, Duane, HUANG, Peter, Qinhua, HEGDE, Sayee, Gajanan, ZHANG, Guobao

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Estrogen receptor modulators von Hegde, Sayee Gajanan, Bunker, Kevin Duane, Zhang, Guobao, Huang, Peter Qinhua

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ESTROGEN RECEPTOR MODULATORS von HEGDE, Sayee, BUNKER, Kevin, HUANG, Peter, ZHANG, Guobao

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SALTS AND FORMS OF AN ESTROGEN RECEPTOR MODULATOR von SLEE, Deborah, Helen, BUNKER, Kevin, Duane, KNIGHT, John, HUANG, Peter, Qinhua, HEGDE, Sayee, Gajanan

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ESTROGEN RECEPTOR MODULATORS von BUNKER, Kevin, Duane, HUANG, Peter, Qinhua, HEGDE, Sayee, Gajanan, ZHANG, Guobao

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Substituted 1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-ones von Liu, Hui, Abraham, Sunny, Paliwal, Sunil, Bunker, Kevin Duane, Unni, Aditya, Hegde, Sayee, Boren, Brant, Hopkins, Chad, Huang, Peter Qinhua

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SUBSTITUTED 1,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES von Liu, Hui, Abraham, Sunny, Paliwal, Sunil, Hegde, Sayee Gajanan, Bunker, Kevin Duane, Unni, Aditya Krishnan, Hopkins, Chad Daniel, Boren, Brant Clayton, Huang, Peter Qinhua

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SALTS AND FORMS OF AN ESTROGEN RECEPTOR MODULATOR von SLEE, Deborah, HEGDE, Sayee, KNIGHT, John, BUNKER, Kevin, HUANG, Peter

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ESTROGEN RECEPTOR MODULATORS von SLEE, Deborah, Helen, PINCHMAN, Joseph, Robert, BUNKER, Kevin, Duane, HUANG, Peter, Qinhua, HEGDE, Sayee, Gajanan, SIT, Rakesh, Kumar, HOPKINS, Chad, Daniel

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ESTROGEN RECEPTOR MODULATORS von SLEE, Deborah, Helen, PINCHMAN, Joseph, Robert, BUNKER, Kevin, Duane, HUANG, Peter, Qinhua, HEGDE, Sayee, Gajanan, SIT, Rakesh, Kumar, HOPKINS, Chad, Daniel

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