Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment von Johnson, G.E., Soeteman-Hernández, L.G., Gollapudi, B.B., Bodger, O.G., Dearfield, K.L., Heflich, R.H., Hixon, J.G., Lovell, D.P., MacGregor, J.T., Pottenger, L.H., Thompson, C.M., Abraham, L., Thybaud, V., Tanir, J.Y., Zeiger, E., van Benthem, J., White, P.A.

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In vitro mammalian cell mutation assays based on the Pig-a gene: A report of the 7th International Workshop on Genotoxicity Testing (IWGT) Workgroup von Bemis, J.C., Heflich, R.H.

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Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests I. Increases in micronucleated bone marrow cells in rodents that do not indicate genot... von TWEATS, D. J, BLAKEY, D, TICE, R, HEFLICH, R. H, JACOBS, A, JACOBSEN, S. D, MORITA, T, NOHMI, T, O'DONOVAN, M. R, SASAKI, Y. F, SOFUNI, T

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Report of the IWGT working group on strategy/interpretation for regulatory in vivo tests II. Identification of in vivo-only positive compounds in the bone marrow micronucleus test von TWEATS, D. J, BLAKEY, D, TICE, R, HEFLICH, R. H, JACOBS, A, JACOBSEN, S. D, MORITA, T, NOHMI, T, O'DONOVAN, M. R, SASAKI, Y. F, SOFUNI, T

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Mutagenicity of comfrey ( ) in rat liver von Mei, N, Guo, L, Fu, P P, Heflich, R H, Chen, T

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Differentiating between micronucleus dose-responses induced by whole cigarette smoke solutions with Benchmark Dose potency ranking von Mittelstaedt, R.A., Shaddock, J.G., Bhalli, J.A., Guo, X., Li, Y., Mei, N., De, M., Richter, P.A., Heflich, R.H.

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Reduction of nitroaromatic compounds by anaerobic bacteria isolated from the human gastrointestinal tract von Rafii, F. (Food and Drug Administration, Jefferson, AR), Franklin, W, Heflich, R.H, Cerniglia, C.E

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In vivo transgenic mutation assays von Thybaud, Véronique, Dean, Stephen, Nohmi, Takehiko, de Boer, Johan, Douglas, George R., Glickman, Barry W., Gorelick, Nancy J., Heddle, John A., Heflich, Robert H., Lambert, Iain, Martus, Hans-Jörg, Mirsalis, Jon C., Suzuki, Takayoshi, Yajima, Nobuhiro

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Evaluation of the transgenic p53+/− mouse for detecting genotoxic liver carcinogens in a short-term bioassay von Balachandra Dass, S, Bucci, Thomas J, Heflich, Robert H, Casciano, Daniel A

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Comparison of the mutations at Hprt exon 3 of T-lymphocytes from B6C3F1 mice and F344 rats exposed by inhalation to 1,3-butadiene or the racemic mixture of 1,2:3,4-diepoxybutane von Meng, Quanxin, Singh, Navjot, Heflich, Robert H, Bauer, Michael J, Walker, Vernon E

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Hprt mutant frequency and molecular analysis of Hprt mutations in Fischer 344 rats treated with thiotepa von TAO CHEN, AIDOO, A, MITTELSTAEDT, R. A, CASCIANO, D. A, HEFLICH, R. H

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Mutations Induced by the Carcinogenic Pyrrolizidine Alkaloid Riddelliine in the Liver cII Gene of Transgenic Big Blue Rats von Mei, Nan, Heflich, Robert H, Chou, Ming W, Chen, Tao

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Fungal metabolism and detoxification of fluoranthene von Pothuluri, J.V, Heflich, R.H, Fu, P.P, Cerniglia, C.E

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Detection of a mouse H-ras codon 61 mutation using a modified allele-specific competitive blocker PCR genotypic selection method von Parsons, Barbara L., Heflich, Robert H.

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Differential mutagenicity of riddelliine in liver endothelial and parenchymal cells of transgenic big blue rats von Mei, Nan, Chou, Ming W., Fu, Peter P., Heflich, Robert H., Chen, Tao

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Genotypic selection methods for the direct analysis of point mutations von Parsons, Barbara L, Heflich, Robert H

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DNA adduct formation and mutation induction by aristolochic acid in rat kidney and liver von Mei, N, Arlt, V M, Phillips, D H, Heflich, R H, Chen, T

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Accumulation and persistence of Pig-A mutant peripheral red blood cells following treatment of rats with single and split doses of N-ethyl- N-nitrosourea von Miura, Daishiro, Dobrovolsky, Vasily N., Kimoto, Takafumi, Kasahara, Yoshinori, Heflich, Robert H.

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Age-dependent sensitivity of Big Blue transgenic mice to the mutagenicity of N-ethyl-N-nitrosourea (ENU) in liver von Mei, N, Heflich, R H, Moore, M M, Chen, T

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DNA adduct formation and T-lymphocyte mutation induction in F344 rats implanted with tumorigenic doses of 1,6-dinitropyrene von SMITH, B. A, FULLERTON, N. F, HEFLICH, R. H, BELAND, F. A

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