Discovery and mechanism of ustekinumab: A human monoclonal antibody targeting interleukin-12 and interleukin-23 for treatment of immune-mediated disorders von Benson, Jacqueline M., Peritt, David, Scallon, Bernard J., Heavner, George A., Shealy, David J., Giles-Komar, Jill M., Mascelli, Mary Ann

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Structural Basis for the Dual Recognition of IL-12 and IL-23 by Ustekinumab von Luo, Jinquan, Wu, Sheng-Jiun, Lacy, Eilyn R., Orlovsky, Yevgeniya, Baker, Audrey, Teplyakov, Alexey, Obmolova, Galina, Heavner, George A., Richter, Hans-Thomas, Benson, Jacqueline

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Interaction of polysorbate 80 with erythropoietin: a case study in protein-surfactant interactions von Villalobos, Annabelle P, Gunturi, Srinivas R, Heavner, George A

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Pharmacodynamic enhancement of the anti-platelet antibody Fab abciximab by site-specific pegylation von Knight, David M., Jordan, Robert E., Kruszynski, Marian, Tam, Susan H., Giles-Komar, Jill, Treacy, George, Heavner, George A.

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Rebuttal Letter von Heavner, George A.

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Probing the solution structure of tumor necrosis factor-α homotrimer and heterotrimer after complex perturbation using electrospray ionization mass spectrometry von Beil, Eric J., Heavner, George A., Wu, Sheng-Jiun, Nemeth, Jennifer F.

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An in vivo model to assess factors that may stimulate the generation of an immune reaction to erythropoietin von Ryan, Mary H., Heavner, George A., Brigham-Burke, Michael, McMahon, Frank, Shanahan, Mary F., Gunturi, Srinivas R., Sharma, Basant, Farrell, Francis X.

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Antibodies Against the First Ig-Like Domain of Human Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Inhibit PECAM-1-Dependent Homophilic Adhesion Block In Vivo Neutro... von Nakada, Marian T, Amin, Kunjlata, Christofidou-Solomidou, Melpo, O'Brien, Christopher D, Sun, Jing, Gurubhagavatula, Indira, Heavner, George A, Taylor, Alexander H, Paddock, Cathy, Sun, Qi-Hong, Zehnder, James L, Newman, Peter J, Albelda, Steven M, DeLisser, Horace M

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Engineering human IL-18 with increased bioactivity and bioavailability von Swencki-Underwood, Bethany, Cunningham, Mark R., Heavner, George A., Blasie, Cheryl, McCarthy, Stephen G., Dougherty, Tara, Brigham-Burke, Mike, Gunn, George R., Goletz, Theresa J., Snyder, Linda A.

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Synthetic, site-specific biotinylated analogs of human MCP-1 von Kruszynski, Marian, Tsui, Ping, Stowell, Nicole, Luo, Jinquan, Nemeth, Jennifer F., Das, Anuk M., Sweet, Raymond, Heavner, George A.

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Synthesis and biological characterization of human monocyte chemoattractant protein 1 (MCP-1) and its analogs von Kruszynski, Marian, Stowell, Nicole, Das, Anuk, Seideman, Jonathan, Tsui, Ping, Brigham-Burke, Michael, Nemeth, Jennifer F., Sweet, Raymond, Heavner, George A.

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A monoclonal antibody and an enzyme immunoassay for human Ala-IL-877 von Nashkevich, Natalia N, Akalovich, Svetlana, Louneva, Natalia, Heavner, George A, Voitenok, Nikolai N

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Proton nuclear magnetic resonance investigation of the active site fragment of splenin, an immunoregulatory polypeptide von Krishna, N. Rama, Heavner, George A, Vaughn, Joseph B

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Nucleotide chemistry. XX. Use of the azido group in the synthesis of 5'-terminal aminodeoxythymidine oligonucleotides von Mungall, William S, Greene, Geoffrey L, Heavner, George A, Letsinger, Robert L

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Structural requirements for the biological activity of thymopentin analogs von Heavner, George A., Audhya, Tapan, Kroon, Daniel, Goldstein, Gideon

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Synthesis of a new photolabile support. 4-(2-Chloropropionyl)phenylacetamidomethyl-resin and its application in solid-phase peptide synthesis von Tjoeng, Foe Siong, Heavner, George A

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Development of an In Vivo Model To Assess Factors That May Stimulate the Generation of an Immune Reaction to Epoetin Alfa von Ryan, Mary H., Shanahan, Mary F., McMahon, Frank, Jolliffe, Linda, Brigham-Burke, Mike, Heavner, George A., Farrell, Francis X.

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Active sequences in cell adhesion molecules: targets for therapeutic intervention von Heavner, George A.

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A monoclonal antibody and an enzyme immunoassay for human Ala-IL-8(77) von Nashkevich, Natalia N, Akalovich, Svetlana, Louneva, Natalia, Heavner, George A, Voitenok, Nikolai N

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A monoclonal antibody and an enzyme immunoassay for human Ala-IL-8 77 von Nashkevich, Natalia N, Akalovich, Svetlana, Louneva, Natalia, Heavner, George A, Voitenok, Nikolai N

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