Pioneer of prostate cancer: past, present and the future of FOXA1 von Teng, Mona, Zhou, Stanley, Cai, Changmeng, Lupien, Mathieu, Hansen He, Housheng

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Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy von Rehman, Sumaiyah K., Haynes, Jennifer, Collignon, Evelyne, Brown, Kevin R., Wang, Yadong, Nixon, Allison M.L., Bruce, Jeffrey P., Wintersinger, Jeffrey A., Singh Mer, Arvind, Lo, Edwyn B.L., Leung, Cherry, Lima-Fernandes, Evelyne, Pedley, Nicholas M., Soares, Fraser, McGibbon, Sophie, He, Housheng Hansen, Pollet, Aaron, Pugh, Trevor J., Haibe-Kains, Benjamin, Morris, Quaid, Ramalho-Santos, Miguel, Goyal, Sidhartha, Moffat, Jason, O’Brien, Catherine A.

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Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1 von Cai, Changmeng, He, Housheng Hansen, Chen, Sen, Coleman, Ilsa, Wang, Hongyun, Fang, Zi, Chen, Shaoyong, Nelson, Peter S., Liu, X. Shirley, Brown, Myles, Balk, Steven P.

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ONECUT2 is a driver of neuroendocrine prostate cancer von Guo, Haiyang, Ci, Xinpei, Ahmed, Musaddeque, Hua, Junjie Tony, Soares, Fraser, Lin, Dong, Puca, Loredana, Vosoughi, Aram, Xue, Hui, Li, Estelle, Su, Peiran, Chen, Sujun, Nguyen, Tran, Liang, Yi, Zhang, Yuzhe, Xu, Xin, Xu, Jing, Sheahan, Anjali V., Ba-Alawi, Wail, Zhang, Si, Mahamud, Osman, Vellanki, Ravi N., Gleave, Martin, Bristow, Robert G., Haibe-Kains, Benjamin, Poirier, John T., Rudin, Charles M., Tsao, Ming-Sound, Wouters, Bradly G., Fazli, Ladan, Feng, Felix Y., Ellis, Leigh, van der Kwast, Theo, Berlin, Alejandro, Koritzinsky, Marianne, Boutros, Paul C., Zoubeidi, Amina, Beltran, Himisha, Wang, Yuzhuo, He, Housheng Hansen

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CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer von Gao, Shanshan, Soares, Fraser, Wang, Shiyan, Wong, Chi Chun, Chen, Huarong, Yang, Zhenjie, Liu, Weixin, Go, Minnie Y. Y., Ahmed, Musaddeque, Zeng, Yong, O’Brien, Catherine Adell, Sung, Joseph J. Y., He, Housheng Hansen, Yu, Jun

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Androgen receptor and MYC equilibration centralizes on developmental super-enhancer von Guo, Haiyang, Wu, Yiming, Nouri, Mannan, Spisak, Sandor, Russo, Joshua W., Sowalsky, Adam G., Pomerantz, Mark M., Wei, Zhao, Korthauer, Keegan, Seo, Ji-Heui, Wang, Liyang, Arai, Seiji, Freedman, Matthew L., He, Housheng Hansen, Chen, Shaoyong, Balk, Steven P.

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RB1 loss in castration-resistant prostate cancer confers vulnerability to LSD1 inhibition von Han, Wanting, Liu, Mingyu, Han, Dong, Li, Muqing, Toure, Anthia A., Wang, Zifeng, Besschetnova, Anna, Patalano, Susan, Macoska, Jill A., Gao, Shuai, He, Housheng Hansen, Cai, Changmeng

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ZNF545 loss promotes ribosome biogenesis and protein translation to initiate colorectal tumorigenesis in mice von Wang, Shiyan, Wong, Chi Chun, Zhang, Yanquan, Huang, Junzhe, Li, Chuangen, Zhai, Jianning, Wang, Guoping, Wei, Hong, Zhang, Xueji, He, Housheng Hansen, Yu, Jun

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Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer von Zhou, Stanley, Hawley, James R., Soares, Fraser, Grillo, Giacomo, Teng, Mona, Madani Tonekaboni, Seyed Ali, Hua, Junjie Tony, Kron, Ken J., Mazrooei, Parisa, Ahmed, Musaddeque, Arlidge, Christopher, Yun, Hwa Young, Livingstone, Julie, Huang, Vincent, Yamaguchi, Takafumi N., Espiritu, Shadrielle M. G., Zhu, Yanyun, Severson, Tesa M., Murison, Alex, Cameron, Sarina, Zwart, Wilbert, van der Kwast, Theodorus, Pugh, Trevor J., Fraser, Michael, Boutros, Paul C., Bristow, Robert G., He, Housheng Hansen, Lupien, Mathieu

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Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse von Fraser, Michael, Livingstone, Julie, Wrana, Jeffrey L., Finelli, Antonio, He, Housheng Hansen, van der Kwast, Theodorus, Zlotta, Alexandre R., Bristow, Robert G., Boutros, Paul C.

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Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development von Xu, Yufei, Xu, Chao, Kato, Akiko, Tempel, Wolfram, Abreu, Jose Garcia, Bian, Chuanbing, Hu, Yeguang, Hu, Di, Zhao, Bin, Cerovina, Tanja, Diao, Jianbo, Wu, Feizhen, He, Housheng Hansen, Cui, Qingyan, Clark, Erin, Ma, Chun, Barbara, Andrew, Veenstra, Gert Jan C., Xu, Guoliang, Kaiser, Ursula B., Liu, X. Shirley, Sugrue, Stephen P., He, Xi, Min, Jinrong, Kato, Yoichi, Shi, Yujiang Geno

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SPOP mutation induces DNA methylation via stabilizing GLP/G9a von Zhang, Jianong, Gao, Kun, Xie, Hongyan, Wang, Dejie, Zhang, Pingzhao, Wei, Ting, Yan, Yuqian, Pan, Yunqian, Ye, Wenbin, Chen, Huifen, Shi, Qing, Li, Yao, Zhao, Shi-min, Hou, Xiaonan, Weroha, Saravut J., Wang, Yuzhuo, Zhang, Jun, Karnes, R. Jeffrey, He, Housheng Hansen, Wang, Liguo, Wang, Chenji, Huang, Haojie

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Androgen Receptor Tumor Suppressor Function Is Mediated by Recruitment of Retinoblastoma Protein von Gao, Shuai, Gao, Yanfei, He, Housheng Hansen, Han, Dong, Han, Wanting, Avery, Amy, Macoska, Jill A., Liu, Xiaming, Chen, Sen, Ma, Fen, Chen, Shaoyong, Balk, Steven P., Cai, Changmeng

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CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer von Ahmed, Musaddeque, Soares, Fraser, Xia, Ji-Han, Yang, Yue, Li, Jing, Guo, Haiyang, Su, Peiran, Tian, Yijun, Lee, Hyung Joo, Wang, Miranda, Akhtar, Nayeema, Houlahan, Kathleen E., Bosch, Almudena, Zhou, Stanley, Mazrooei, Parisa, Hua, Junjie T., Chen, Sujun, Petricca, Jessica, Zeng, Yong, Davies, Alastair, Fraser, Michael, Quigley, David A., Feng, Felix Y., Boutros, Paul C., Lupien, Mathieu, Zoubeidi, Amina, Wang, Liang, Walsh, Martin J., Wang, Ting, Ren, Shancheng, Wei, Gong-Hong, He, Housheng Hansen

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Lysine-specific demethylase 1 has dual functions as a major regulator of androgen receptor transcriptional activity von Cai, Changmeng, He, Housheng Hansen, Gao, Shuai, Chen, Sen, Yu, Ziyang, Gao, Yanfei, Chen, Shaoyong, Chen, Mei Wei, Zhang, Jesse, Ahmed, Musaddeque, Wang, Yang, Metzger, Eric, Schüle, Roland, Liu, X Shirley, Brown, Myles, Balk, Steven P

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Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes von Kent, Oliver A., Saha, Manipa, Coyaud, Etienne, Burston, Helen E., Law, Napoleon, Dadson, Keith, Chen, Sujun, Laurent, Estelle M., St-Germain, Jonathan, Sun, Ren X., Matsumoto, Yoshinori, Cowen, Justin, Montgomery-Song, Aaryn, Brown, Kevin R., Ishak, Charles, Rose, Jose La, De Carvalho, Daniel D., He, Housheng Hansen, Raught, Brian, Billia, Filio, Kannu, Peter, Rottapel, Robert

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HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness von Ho, Jessica S. Y., Di Tullio, Federico, Schwarz, Megan, Low, Diana, Incarnato, Danny, Gay, Florence, Tabaglio, Tommaso, Zhang, JingXian, Wollmann, Heike, Chen, Leilei, An, Omer, Chan, Tim Hon Man, Hickman, Alexander Hall, Zheng, Simin, Roudko, Vladimir, Chen, Sujun, Karz, Alcida, Ahmed, Musaddeque, He, Housheng Hansen, Greenbaum, Benjamin D., Oliviero, Salvatore, Serresi, Michela, Gargiulo, Gaetano, Mann, Karen M., Hernando, Eva, Mulholland, David, Marazzi, Ivan, Wee, Dave Keng Boon, Guccione, Ernesto

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GlcNAcylation of histone H2B facilitates its monoubiquitination von Fujiki, Ryoji, Hashiba, Waka, Sekine, Hiroki, Yokoyama, Atsushi, Chikanishi, Toshihiro, Ito, Saya, Imai, Yuuki, Kim, Jaehoon, He, Housheng Hansen, Igarashi, Katsuhide, Kanno, Jun, Ohtake, Fumiaki, Kitagawa, Hirochika, Roeder, Robert G., Brown, Myles, Kato, Shigeaki

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Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression von Chen, Sujun, Zhu, Guanghui, Yang, Yue, Wang, Fubo, Xiao, Yu-Tian, Zhang, Na, Bian, Xiaojie, Zhu, Yasheng, Yu, Yongwei, Liu, Fei, Dong, Keqin, Mariscal, Javier, Liu, Yin, Soares, Fraser, Loo Yau, Helen, Zhang, Bo, Chen, Weidong, Wang, Chao, Chen, Dai, Guo, Qinghua, Yi, Zhengfang, Liu, Mingyao, Fraser, Michael, De Carvalho, Daniel D., Boutros, Paul C., Di Vizio, Dolores, Jiang, Zhou, van der Kwast, Theodorus, Berlin, Alejandro, Wu, Song, Wang, Jianhua, He, Housheng Hansen, Ren, Shancheng

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Hepatic Fibroblast Growth Factor 21 Is Involved in Mediating Functions of Liraglutide in Mice With Dietary Challenge von Liu, Dinghui, Pang, Juan, Shao, Weijuan, Gu, Jianqiu, Zeng, Yong, He, Housheng Hansen, Ling, Wenhua, Qian, Xiaoxian, Jin, Tianru

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