Hsp90, an unlikely ally in the war on cancer von Barrott, Jared J., Haystead, Timothy A. J.

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Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice von Scarneo, Scott A, Eibschutz, Liesl S, Bendele, Phillip J, Yang, Kelly W, Totzke, Juliane, Hughes, Philip, Fox, David A, Haystead, Timothy A J

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Death‐associated protein kinase 3 regulates the myogenic reactivity of cerebral arteries von Turner, Sara R., Al‐Ghabkari, Abdulhameed, Carlson, David A., Chappellaz, Mona, Sutherland, Cindy, Haystead, Timothy A. J., Cole, William C., MacDonald, Justin A.

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Molecular Biologist's Guide to Proteomics von GRAVES, Paul R, HAYSTEAD, Timothy A. J

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Expression of membrane Hsp90 is a molecular signature of T cell activation von Scarneo, Scott A., Smith, Aaron P., Favret, Jacob, O’Connell, Robert, Pickeral, Joy, Yang, Kelly W., Ferrari, Guido, Loiselle, David R., Hughes, Philip F., Kulkarni, Manjusha M., Gargesha, Madhusudhana, Scott, Bryan, Roy, Debashish, Haynes, Barton F., Kwiek, Jesse J., Haystead, Timothy A. J.

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Fluorescence Linked Enzyme Chemoproteomic Strategy for Discovery of a Potent and Selective DAPK1 and ZIPK Inhibitor von Carlson, David A, Franke, Aaron S, Weitzel, Douglas H, Speer, Brittany L, Hughes, Philip F, Hagerty, Laura, Fortner, Christopher N, Veal, James M, Barta, Thomas E, Zieba, Bartosz J, Somlyo, Avril V, Sutherland, Cindy, Deng, Jing Ti, Walsh, Michael P, MacDonald, Justin A, Haystead, Timothy A. J

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TAK1: a potent tumour necrosis factor inhibitor for the treatment of inflammatory diseases von Totzke, Juliane, Scarneo, Scott A., Yang, Kelly W., Haystead, Timothy A. J.

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Genetic and pharmacological validation of TAK1 inhibition in macrophages as a therapeutic strategy to effectively inhibit TNF secretion von Scarneo, Scott A., Mansourati, Antoine, Eibschutz, Liesl S., Totzke, Juliane, Roques, Jose R., Loiselle, David, Carlson, David, Hughes, Philip, Haystead, Timothy A. J.

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role of the calponin homology domain of smoothelin-like 1 (SMTNL1) in myosin phosphatase inhibition and smooth muscle contraction von Borman, Meredith A, Freed, Tiffany A, Haystead, Timothy A. J, MacDonald, Justin A

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A Small Molecule Pyrazolo[3,4-d]Pyrimidinone Inhibitor of Zipper-Interacting Protein Kinase Suppresses Calcium Sensitization of Vascular Smooth Muscle von MacDonald, Justin A., Sutherland, Cindy, Carlson, David A., Bhaidani, Sabreena, Al-Ghabkari, Abdulhameed, Swärd, Karl, Haystead, Timothy A.J., Walsh, Michael P.

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An inducible heat shock protein 70 small molecule inhibitor demonstrates anti-dengue virus activity, validating Hsp70 as a host antiviral target von Howe, Matthew K, Speer, Brittany L, Hughes, Philip F, Loiselle, David R, Vasudevan, Subhash, Haystead, Timothy A J

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Combination of a novel heat shock protein 90-targeted photodynamic therapy with PD-1/PD-L1 blockade induces potent systemic antitumor efficacy and abscopal effect against breast ca... von Kaneko, Kensuke, Acharya, Chaitanya R, Nagata, Hiroshi, Yang, Xiao, Hartman, Zachary Conrad, Hobeika, Amy, Hughes, Philip F, Haystead, Timothy A J, Morse, Michael A, Lyerly, Herbert Kim, Osada, Takuya

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Smoothelin-like 1 deletion enhances myogenic reactivity of mesenteric arteries with alterations in PKC and myosin phosphatase signaling von Turner, Sara R., Chappellaz, Mona, Popowich, Brittany, Wooldridge, Anne A., Haystead, Timothy A. J., Cole, William C., MacDonald, Justin A.

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Deletion of the Protein Kinase A/Protein Kinase G Target SMTNL1 Promotes an Exercise-adapted Phenotype in Vascular Smooth Muscle von Wooldridge, Anne A., Fortner, Christopher N., Lontay, Beata, Akimoto, Takayuki, Neppl, Ronald L., Facemire, Carie, Datto, Michael B., Kwon, Ashley, McCook, Everett, Li, Ping, Wang, Shiliang, Thresher, Randy J., Miller, Sara E., Perriard, Jean-Claude, Gavin, Timothy P., Hickner, Robert C., Coffman, Thomas M., Somlyo, Avril V., Yan, Zhen, Haystead, Timothy A.J.

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Angiotensin II Type 1A Receptors in Vascular Smooth Muscle Cells Do Not Influence Aortic Remodeling in Hypertension von Sparks, Matthew A, Parsons, Kelly K, Stegbauer, Johannes, Gurley, Susan B, Vivekanandan-Giri, Anuradha, Fortner, Christopher N, Snouwaert, Jay, Raasch, Eric W, Griffiths, Robert C, Haystead, Timothy A.J, Le, Thu H, Pennathur, Subramaniam, Koller, Beverly, Coffman, Thomas M

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Kinetic Mechanism of Quinone Oxidoreductase 2 and Its Inhibition by the Antimalarial Quinolines von Kwiek, Jesse J, Haystead, Timothy A. J, Rudolph, Johannes

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ROCK1 Phosphorylates and Activates Zipper-interacting Protein Kinase von Hagerty, Laura, Weitzel, Douglas H., Chambers, Jenica, Fortner, Christopher N., Brush, Matthew H., Loiselle, David, Hosoya, Hiroshi, Haystead, Timothy A.J.

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A highly selective Hsp90 affinity chromatography resin with a cleavable linker von Hughes, Philip F., Barrott, Jared J., Carlson, David A., Loiselle, David R., Speer, Brittany L., Bodoor, Khaldon, Rund, Lauretta A., Haystead, Timothy A.J.

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Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2+ Breast Cancer von Alwarawrah, Yazan, Hughes, Philip, Loiselle, David, Carlson, David A., Darr, David B., Jordan, Jamie L., Xiong, Jessie, Hunter, Lucas M., Dubois, Laura G., Thompson, J. Will, Kulkarni, Manjusha M., Ratcliff, Annette N., Kwiek, Jesse J., Haystead, Timothy A.J.

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Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease von Totzke, Juliane, Gurbani, Deepak, Raphemot, Rene, Hughes, Philip F., Bodoor, Khaldon, Carlson, David A., Loiselle, David R., Bera, Asim K., Eibschutz, Liesl S., Perkins, Marisha M., Eubanks, Amber L., Campbell, Phillip L., Fox, David A., Westover, Kenneth D., Haystead, Timothy A.J., Derbyshire, Emily R.

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