The Nrf2 regulatory network provides an interface between redox and intermediary metabolism von Hayes, John D., Dinkova-Kostova, Albena T.

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NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer von Hayes, John D., McMahon, Michael

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Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases von Cuadrado, Antonio, Rojo, Ana I., Wells, Geoffrey, Hayes, John D., Cousin, Sharon P., Rumsey, William L., Attucks, Otis C., Franklin, Stephen, Levonen, Anna-Liisa, Kensler, Thomas W., Dinkova-Kostova, Albena T.

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SCF/β-TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner von Rada, Patricia, Rojo, Ana I., Chowdhry, Sudhir, McMahon, Michael, Hayes, John D., Cuadrado, Antonio

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p62/SQSTM1 Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription von Jain, Ashish, Lamark, Trond, Sjøttem, Eva, Bowitz Larsen, Kenneth, Atesoh Awuh, Jane, Øvervatn, Aud, McMahon, Michael, Hayes, John D., Johansen, Terje

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Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway von Hayes, John D, McMahon, Michael, Chowdhry, Sudhir, Dinkova-Kostova, Albena T

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Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals von McMahon, Michael, Lamont, Douglas J., Beattie, Kenneth A., Hayes, John D., Murphy, Mike P.

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Transcription factor Nrf1 is topologically repartitioned across membranes to enable target gene transactivation through its acidic glucose-responsive domains von Zhang, Yiguo, Ren, Yonggang, Li, Shaojun, Hayes, John D

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NRF2 and the Ambiguous Consequences of Its Activation during Initiation and the Subsequent Stages of Tumourigenesis von Robertson, Holly, Dinkova-Kostova, Albena T., Hayes, John D.

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Glutathione transferases von HAYES, John D, FLANAGAN, Jack U, JOWSEY, Ian R

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Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/β-TrCP Axis von Rada, Patricia, Rojo, Ana I., Evrard-Todeschi, Nathalie, Innamorato, Nadia G., Cotte, Axelle, Jaworski, Tomasz, Tobón-Velasco, Julio C., Devijver, Herman, García-Mayoral, María Flor, Van Leuven, Fred, Hayes, John D., Bertho, Gildas, Cuadrado, Antonio

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Keap1-dependent Proteasomal Degradation of Transcription Factor Nrf2 Contributes to the Negative Regulation of Antioxidant Response Element-driven Gene Expression von McMahon, Michael, Itoh, Ken, Yamamoto, Masayuki, Hayes, John D.

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Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes von Ohtsuji, Makiko, Katsuoka, Fumiki, Kobayashi, Akira, Aburatani, Hiroyuki, Hayes, John D., Yamamoto, Masayuki

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Oxidative Stress in Cancer von Hayes, John D., Dinkova-Kostova, Albena T., Tew, Kenneth D.

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cancer chemopreventive actions of phytochemicals derived from glucosinolates von Hayes, John D, Kelleher, Michael O, Eggleston, Ian M

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Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2) von Sharma, Ritu S, Harrison, David J, Kisielewski, Dorothy, Cassidy, Diane M, McNeilly, Alison D, Gallagher, Jennifer R, Walsh, Shaun V, Honda, Tadashi, McCrimmon, Rory J, Dinkova-Kostova, Albena T, Ashford, Michael L.J, Dillon, John F, Hayes, John D

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Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha von Wang, Xiu Jun, Hayes, John D, Henderson, Colin J, Wolf, C. Roland

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Induction of the Antioxidant Response by the Transcription Factor NRF2 Increases Bioactivation of the Mutagenic Air Pollutant 3‑Nitrobenzanthrone in Human Lung Cells von Murray, Jessica R, de la Vega, Laureano, Hayes, John D, Duan, Ling, Penning, Trevor M

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Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis von Chowdhry, Sudhir, Nazmy, Maiiada H., Meakin, Paul J., Dinkova-Kostova, Albena T., Walsh, Shaun V., Tsujita, Tadayuki, Dillon, John F., Ashford, Michael L.J., Hayes, John D.

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Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence von Nioi, Paul, McMahon, Michael, Itoh, Ken, Yamamoto, Masayuki, Hayes, John D

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