Genetic Landscape of Human Papillomavirus-Associated Head and Neck Cancer and Comparison to Tobacco-Related Tumors von Hayes, D Neil, Van Waes, Carter, Seiwert, Tanguy Y

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Increasing Incidence of Oral Tongue Squamous Cell Carcinoma in Young White Women, Age 18 to 44 Years von PATEL, Sagar C, CARPENTER, William R, TYREE, Seth, EVERETT COUCH, Marion, WEISSLER, Mark, HACKMAN, Trevor, NEIL HAYES, D, SHORES, Carol, CHERA, Bhishamjit S

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Lung Adenocarcinoma and Squamous Cell Carcinoma Gene Expression Subtypes Demonstrate Significant Differences in Tumor Immune Landscape von Faruki, Hawazin, Mayhew, Gregory M., Serody, Jonathan S., Hayes, D. Neil, Perou, Charles M., Lai-Goldman, Myla

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Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors von Akbay, Esra A, Koyama, Shohei, Carretero, Julian, Altabef, Abigail, Tchaicha, Jeremy H, Christensen, Camilla L, Mikse, Oliver R, Cherniack, Andrew D, Beauchamp, Ellen M, Pugh, Trevor J, Wilkerson, Matthew D, Fecci, Peter E, Butaney, Mohit, Reibel, Jacob B, Soucheray, Margaret, Cohoon, Travis J, Janne, Pasi A, Meyerson, Matthew, Hayes, D Neil, Shapiro, Geoffrey I, Shimamura, Takeshi, Sholl, Lynette M, Rodig, Scott J, Freeman, Gordon J, Hammerman, Peter S, Dranoff, Glenn, Wong, Kwok-Kin

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ABRA: improved coding indel detection via assembly-based realignment von Mose, Lisle E, Wilkerson, Matthew D, Hayes, D Neil, Perou, Charles M, Parker, Joel S

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Hedgehog-GLI Signaling Inhibition Suppresses Tumor Growth in Squamous Lung Cancer von LINGLING HUANG, WALTER, Vonn, HAYES, D. Neil, ONAITIS, Mark

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Fbxw7 is a driver of uterine carcinosarcoma by promoting epithelial-mesenchymal transition von Cuevas, Ileana C., Sahoo, Subhransu S., Kumar, Ashwani, Zhang, He, Westcott, Jill, Aguilar, Mitzi, Cortez, Jeremy D., Sullivan, Stephanie A., Xing, Chao, Hayes, D. Neil, Brekken, Rolf A., Bae-Jump, Victoria L., Castrillon, Diego H.

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Identification of Clonal Hematopoiesis Mutations in Solid Tumor Patients Undergoing Unpaired Next-Generation Sequencing Assays von Coombs, Catherine C, Gillis, Nancy K, Tan, Xianming, Berg, Jonathan S, Ball, Markus, Balasis, Maria E, Montgomery, Nathan D, Bolton, Kelly L, Parker, Joel S, Mesa, Tania E, Yoder, Sean J, Hayward, Michele C, Patel, Nirali M, Richards, Kristy L, Walko, Christine M, Knepper, Todd C, Soper, John T, Weiss, Jared, Grilley-Olson, Juneko E, Kim, William Y, Earp, 3rd, H Shelton, Levine, Ross L, Papaemmanuil, Elli, Zehir, Ahmet, Hayes, D Neil, Padron, Eric

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Therapeutic insights from genomic studies of head and neck squamous cell carcinomas von Hammerman, Peter S, Hayes, D Neil, Grandis, Jennifer R

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Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer von Ju, Young Seok, Alexandrov, Ludmil B, Gerstung, Moritz, Martincorena, Inigo, Nik-Zainal, Serena, Ramakrishna, Manasa, Davies, Helen R, Papaemmanuil, Elli, Gundem, Gunes, Shlien, Adam, Bolli, Niccolo, Behjati, Sam, Tarpey, Patrick S, Nangalia, Jyoti, Massie, Charles E, Butler, Adam P, Teague, Jon W, Vassiliou, George S, Green, Anthony R, Du, Ming-Qing, Unnikrishnan, Ashwin, Pimanda, John E, Teh, Bin Tean, Munshi, Nikhil, Greaves, Mel, Vyas, Paresh, El-Naggar, Adel K, Santarius, Tom, Collins, V Peter, Grundy, Richard, Taylor, Jack A, Hayes, D Neil, Malkin, David, Foster, Christopher S, Warren, Anne Y, Whitaker, Hayley C, Brewer, Daniel, Eeles, Rosalind, Cooper, Colin, Neal, David, Visakorpi, Tapio, Isaacs, William B, Bova, G Steven, Flanagan, Adrienne M, Futreal, P Andrew, Lynch, Andy G, Chinnery, Patrick F, McDermott, Ultan, Stratton, Michael R, Campbell, Peter J

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BRG1/SMARCA4 inactivation promotes non-small cell lung cancer aggressiveness by altering chromatin organization von Orvis, Tess, Hepperla, Austin, Walter, Vonn, Song, Shujie, Simon, Jeremy, Parker, Joel, Wilkerson, Matthew D, Desai, Nisarg, Major, Michael B, Hayes, D Neil, Davis, Ian J, Weissman, Bernard

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PIK3CA Mutation in HPV-Associated OPSCC Patients Receiving Deintensified Chemoradiation von Beaty, Brian T, Moon, Dominic H, Shen, Colette J, Amdur, Robert J, Weiss, Jared, Grilley-Olson, Juneko, Patel, Shetal, Zanation, Adam, Hackman, Trevor G, Thorp, Brian, Blumberg, Jeffrey M, Patel, Samip N, Weissler, Mark C, Yarbrough, Wendell G, Sheets, Nathan C, Parker, Joel S, Neil Hayes, D, Weck, Karen E, Ramkissoon, Lori A, Mendenhall, William M, Dagan, Roi, Tan, Xianming, Gupta, Gaorav P, Chera, Bhishamjit S

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Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss von Gross, Andrew M, Orosco, Ryan K, Shen, John P, Egloff, Ann Marie, Carter, Hannah, Hofree, Matan, Choueiri, Michel, Coffey, Charles S, Lippman, Scott M, Hayes, D Neil, Cohen, Ezra E, Grandis, Jennifer R, Nguyen, Quyen T, Ideker, Trey

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A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response von Chen, Zhao, Cheng, Katherine, Walton, Zandra, Wang, Yuchuan, Ebi, Hiromichi, Shimamura, Takeshi, Liu, Yan, Tupper, Tanya, Ouyang, Jing, Li, Jie, Gao, Peng, Woo, Michele S., Xu, Chunxiao, Yanagita, Masahiko, Altabef, Abigail, Wang, Shumei, Lee, Charles, Nakada, Yuji, Peña, Christopher G., Sun, Yanping, Franchetti, Yoko, Yao, Catherine, Saur, Amy, Cameron, Michael D., Nishino, Mizuki, Hayes, D. Neil, Wilkerson, Matthew D., Roberts, Patrick J., Lee, Carrie B., Bardeesy, Nabeel, Butaney, Mohit, Chirieac, Lucian R., Costa, Daniel B., Jackman, David, Sharpless, Norman E., Castrillon, Diego H., Demetri, George D., Jänne, Pasi A., Pandolfi, Pier Paolo, Cantley, Lewis C., Kung, Andrew L., Engelman, Jeffrey A., Wong, Kwok-Kin

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SCISSOR: a framework for identifying structural changes in RNA transcripts von Choi, Hyo Young, Jo, Heejoon, Zhao, Xiaobei, Hoadley, Katherine A., Newman, Scott, Holt, Jeremiah, Hayward, Michele C., Love, Michael I., Marron, J. S., Hayes, D. Neil

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Inhibitor-Sensitive FGFR2 and FGFR3 Mutations in Lung Squamous Cell Carcinoma von LIAO, Rachel G, JUNG, Joonil, GRAY, Nathanael S, GETZ, Gad, WONG, Kwok-Kin, HADDAD, Robert I, MEYERSON, Matthew, HAMMERMAN, Peter S, TCHAICHA, Jeremy, WILKERSON, Matthew D, SIVACHENKO, Andrey, BEAUCHAMP, Ellen M, QINGSONG LIU, PUGH, Trevor J, PEDAMALLUL, Chandra Sekhar, HAYES, D. Neil

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Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI von Kreimer, Aimée R., Chaturvedi, Anil K., Alemany, Laia, Anantharaman, Devasena, Bray, Freddie, Carrington, Mary, Doorbar, John, D'Souza, Gypsyamber, Fakhry, Carole, Ferris, Robert L., Gillison, Maura, Neil Hayes, D., Hildesheim, Allan, Huang, Shao Hui, Kowalski, Luiz P., Lang Kuhs, Krystle A., Lewis, James, Lowy, Douglas R., Mehanna, Hisham, Ness, Andy, Pawlita, Michael, Pinheiro, Maisa, Schiller, John, Shiels, Meredith S., Tota, Joseph, Mirabello, Lisa, Warnakulasuriya, Saman, Waterboer, Tim, Westra, William, Chanock, Stephen, Brennan, Paul

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Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes von Walter, Vonn, Yin, Xiaoying, Wilkerson, Matthew D, Cabanski, Christopher R, Zhao, Ni, Du, Ying, Ang, Mei Kim, Hayward, Michele C, Salazar, Ashley H, Hoadley, Katherine A, Fritchie, Karen, Sailey, Charles J, Sailey, Charles G, Weissler, Mark C, Shockley, William W, Zanation, Adam M, Hackman, Trevor, Thorne, Leigh B, Funkhouser, William D, Muldrew, Kenneth L, Olshan, Andrew F, Randell, Scott H, Wright, Fred A, Shores, Carol G, Hayes, D Neil

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Lung Squamous Cell Carcinoma mRNA Expression Subtypes Are Reproducible, Clinically Important, and Correspond to Normal Cell Types von WILKERSON, Matthew D, XIAOYING YIN, PARSONS, Alden M, FUNKHOUSER, William K, LEE, Carrie B, ROBERTS, Patrick J, THORNE, Leigh, BERNARD, Philip S, PEROU, Charles M, HAYS, D. Neil, HOADLEY, Katherine A, YUFENG LIU, HAYWARD, Michele C, CABANSKI, Christopher R, MULDREW, Kenneth, MILLER, C. Ryan, RANDELL, Scott H, SOCINSKI, Mark A

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Germline Analysis from Tumor-Germline Sequencing Dyads to Identify Clinically Actionable Secondary Findings von Seifert, Bryce A, O'Daniel, Julianne M, Amin, Krunal, Marchuk, Daniel S, Patel, Nirali M, Parker, Joel S, Hoyle, Alan P, Mose, Lisle E, Marron, Andrew, Hayward, Michele C, Bizon, Christopher, Wilhelmsen, Kirk C, Evans, James P, Earp, 3rd, H Shelton, Sharpless, Norman E, Hayes, D Neil, Berg, Jonathan S

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