Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML von Tothova, Zuzana, Valton, Anne-Laure, Gorelov, Rebecca A, Vallurupalli, Mounica, Krill-Burger, John M, Holmes, Amie, Landers, Catherine C, Haydu, J Erika, Malolepsza, Edyta, Hartigan, Christina, Donahue, Melanie, Popova, Katerina D, Koochaki, Sebastian, Venev, Sergey V, Rivera, Jeanne, Chen, Edwin, Lage, Kasper, Schenone, Monica, D'Andrea, Alan D, Carr, Steven A, Morgan, Elizabeth A, Dekker, Job, Ebert, Benjamin L

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Humoral and cellular immunogenicity of SARS-CoV-2 vaccines in chronic lymphocytic leukemia: a prospective cohort study von Haydu, J. Erika, Maron, Jenny S., Redd, Robert A., Gallagher, Kathleen M.E., Fischinger, Stephanie, Barnes, Jeffrey A., Hochberg, Ephraim P., Johnson, P. Connor, Takvorian, R.W., Katsis, Katelin, Portman, Daneal, Ruiters, Jade, Sechio, Sidney, Devlin, Mary, Regan, Connor, Blumenthal, Kimberly G., Banerji, Aleena, Judd, Allen D., Scorsune, Krista J., McGree, Brianne M., Sherburne, Maryanne M., Lynch, Julia M., Weitzman, James I., Lei, Matthew, Kotton, Camille N., Dighe, Anand S., Maus, Marcela V., Alter, Galit, Abramson, Jeremy S., Soumerai, Jacob D.

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An activating intragenic deletion in NOTCH1 in human T-ALL von Haydu, J. Erika, De Keersmaecker, Kim, Duff, Mary Kaye, Paietta, Elisabeth, Racevskis, Janis, Wiernik, Peter H., Rowe, Jacob M., Ferrando, Adolfo

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Prediction of life-threatening and disabling bleeding in patients with AML receiving intensive induction chemotherapy von Versluis, Jurjen, Pandey, Manu, Flamand, Yael, Haydu, J. Erika, Belizaire, Roger, Faber, Mark, Vedula, Rahul S., Charles, Anne, Copson, Kevin M., Shimony, Shai, Rozental, Alon, Bendapudi, Pavan K., Wolach, Ofir, Griffiths, Elizabeth A., Thompson, James E., Stone, Richard M., DeAngelo, Daniel J., Neuberg, Donna, Luskin, Marlise R., Wang, Eunice S., Lindsley, R. Coleman

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Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas von Palomero, Teresa, Couronné, Lucile, Khiabanian, Hossein, Kim, Mi-Yeon, Ambesi-Impiombato, Alberto, Perez-Garcia, Arianne, Carpenter, Zachary, Abate, Francesco, Allegretta, Maddalena, Haydu, J Erika, Jiang, Xiaoyu, Lossos, Izidore S, Nicolas, Concha, Balbin, Milagros, Bastard, Christian, Bhagat, Govind, Piris, Miguel A, Campo, Elias, Bernard, Olivier A, Rabadan, Raul, Ferrando, Adolfo A

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Early T-cell precursor acute lymphoblastic leukaemia von Haydu, J Erika, Ferrando, Adolfo A

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Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia von Herranz, Daniel, Ambesi-Impiombato, Alberto, Sudderth, Jessica, Sánchez-Martín, Marta, Belver, Laura, Tosello, Valeria, Xu, Luyao, Wendorff, Agnieszka A, Castillo, Mireia, Haydu, J Erika, Márquez, Javier, Matés, José M, Kung, Andrew L, Rayport, Stephen, Cordon-Cardo, Carlos, DeBerardinis, Ralph J, Ferrando, Adolfo A

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Physiological Jak2V617F Expression Causes a Lethal Myeloproliferative Neoplasm with Differential Effects on Hematopoietic Stem and Progenitor Cells von Mullally, Ann, Lane, Steven W., Ball, Brian, Megerdichian, Christine, Okabe, Rachel, Al-Shahrour, Fatima, Paktinat, Mahnaz, Haydu, J. Erika, Housman, Elizabeth, Lord, Allegra M., Wernig, Gerlinde, Kharas, Michael G., Mercher, Thomas, Kutok, Jeffery L., Gilliland, D. Gary, Ebert, Benjamin L.

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ETV6 mutations in early immature human T cell leukemias von Van Vlierberghe, Pieter, Ambesi-Impiombato, Alberto, Perez-Garcia, Arianne, Haydu, J Erika, Rigo, Isaura, Hadler, Michael, Tosello, Valeria, Della Gatta, Giusy, Paietta, Elisabeth, Racevskis, Janis, Wiernik, Peter H, Luger, Selina M, Rowe, Jacob M, Rue, Montserrat, Ferrando, Adolfo A

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Cell Confluence Regulates Hepatocyte Growth Factor-Stimulated Cell Morphogenesis in a β-Catenin-Dependent Manner von Ishibe, Shuta, Haydu, J. Erika, Togawa, Akashi, Marlier, Arnaud, Cantley, Lloyd G.

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The rules of T-cell engagement: current state of CAR T cells and bispecific antibodies in B-cell lymphomas von Haydu, J. Erika, Abramson, Jeremy S.

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Niche-based screening identifies small-molecule inhibitors of leukemia stem cells von Hartwell, Kimberly A, Miller, Peter G, Mukherjee, Siddhartha, Kahn, Alissa R, Stewart, Alison L, Logan, David J, Negri, Joseph M, Duvet, Mildred, Järås, Marcus, Puram, Rishi, Dancik, Vlado, Al-Shahrour, Fatima, Kindler, Thomas, Tothova, Zuzana, Chattopadhyay, Shrikanta, Hasaka, Thomas, Narayan, Rajiv, Dai, Mingji, Huang, Christina, Shterental, Sebastian, Chu, Lisa P, Haydu, J Erika, Shieh, Jae Hung, Steensma, David P, Munoz, Benito, Bittker, Joshua A, Shamji, Alykhan F, Clemons, Paul A, Tolliday, Nicola J, Carpenter, Anne E, Gilliland, D Gary, Stern, Andrew M, Moore, Malcolm A S, Scadden, David T, Schreiber, Stuart L, Ebert, Benjamin L, Golub, Todd R

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Pretreatment clinical and genetic factors predict early post‐treatment mortality in fit AML patients following induction von Haydu, J. Erika, Flamand, Yael, Vedula, Rahul S., Versluis, Jurjen, Charles, Anne, Copson, Kevin M., Stone, Richard M., DeAngelo, Daniel J., Neuberg, Donna, Lindsley, R. Coleman, Luskin, Marlise R.

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K-RasG12D–induced T-cell lymphoblastic lymphoma/leukemias harbor Notch1 mutations and are sensitive to γ-secretase inhibitors von Kindler, Thomas, Cornejo, Melanie G., Scholl, Claudia, Liu, Jianing, Leeman, Dena S., Haydu, J. Erika, Fröhling, Stefan, Lee, Benjamin H., Gilliland, D. Gary

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Distinct Clinical and Genetic Factors Predict Early Versus Late Mortality in AML Patients Undergoing Induction Chemotherapy von Haydu, J. Erika, Flamand, Yael, Vedula, Rahul S., Versluis, Jurjen, Charles, Anne, Copson, Kevin, Neuberg, Donna S., Lindsley, R. Coleman, Luskin, Marlise R

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Incidence and Risk Factors for Bleeding in Patients with Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy von Versluis, Jurjen, Flamand, Yael, Haydu, Erika J., Vedula, Rahul S., Charles, Anne, Copson, Kevin, Wolach, Ofir, Bendapudi, Pavan, Belizaire, Roger, Neuberg, Donna S., Luskin, Marlise R, Lindsley, R. Coleman

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STAG2 Mutations Alter Cohesin Ring Function and Provide Therapeutic Vulnerabilities in Acute Myeloid Leukemia von Tothova, Zuzana, Krill-Burger, John M., Day, Daniel S., Haydu, J. Erika, Abraham, Brian J., Landers, Catherine C., Malolepsza, Edyta, Hartigan, Christina R., Holmes, Amie, Donahue, Melanie, Popova, Katerina D., Koochaki, Sebastian, Rivera, Jeanne, Seiler, Michael, Hnisz, Denes, Chen, Edwin, Buonamici, Silvia, Schenone, Monica, D'Andrea, Alan D., Carr, Steven A., Young, Richard A., Ebert, Benjamin L.

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Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in acute lymphoblastic leukemia von Herranz, Daniel, Ambesi-Impiombato, Alberto, Sudderth, Jessica, Sánchez-Martín, Marta, Belver, Laura, Tosello, Valeria, Xu, Luyao, Wendorff, Agnieszka A., Castillo, Mireia, Haydu, J. Erika, Márquez, Javier, Matés, José M., Kung, Andrew L., Rayport, Stephen, Cordon-Cardo, Carlos, DeBerardinis, Ralph J., Ferrando, Adolfo A.

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ETV6 mutations in early immature human T cell leukemias von Van Vlierberghe, Pieter, Ambesi-Impiombato, Alberto, Perez-Garcia, Arianne, Haydu, J Erika, Rigo, Isaura, Hadler, Michael, Tosello, Valeria, Della Gatta, Giusy, Paietta, Elisabeth, Racevskis, Janis, Wiernik, Peter H, Luger, Selina M, Rowe, Jacob M, Rue, Montserrat, Ferrando, Adolfo A

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Niche-Based Screening Reveals Leukemia Stem Cell Specific Therapeutics von Hartwell, Kimberly A., Miller, Peter G., Stewart, Alison L., Kahn, Alissa R., Logan, David J., Negri, Joseph, Duvet, Mildred, Chattopadhyay, Shrikanta, Shterental, Sebastian, Chu, Lisa P, Shieh, Jae Hung, Jaeraas, Marcus, Dancik, Vladimir, Narayan, Rajiv, Huang, Christina, Haydu, J Erika, Mukherjee, Siddhartha, Shamji, Alykhan F, Tolliday, Nicola J, Carpenter, Anne E., Schreiber, Stuart L., Stern, Andrew M., Moore, Malcolm AS, Scadden, David T., Ebert, Benjamin L., Golub, Todd R.

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