Identification of a periplasmic AlgK–AlgX–MucD multiprotein complex in Pseudomonas aeruginosa involved in biosynthesis and regulation of alginate von Hay, Iain David, Schmidt, Oliver, Filitcheva, Jana, Rehm, Bernd H. A.

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Ct threshold values, a proxy for viral load in community SARS-CoV-2 cases, demonstrate wide variation across populations and over time von Walker, A Sarah, Pritchard, Emma, House, Thomas, Robotham, Julie V, Birrell, Paul J, Bell, Iain, Bell, John I, Newton, John N, Farrar, Jeremy, Diamond, Ian, Studley, Ruth, Hay, Jodie, Vihta, Karina-Doris, Peto, Timothy Ea, Stoesser, Nicole, Matthews, Philippa C, Eyre, David W, Pouwels, Koen B

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Adaptation of the periplasm to maintain spatial constraints essential for cell envelope processes and cell viability von Mandela, Eric, Stubenrauch, Christopher J, Ryoo, David, Hwang, Hyea, Cohen, Eli J, Torres, Von L, Deo, Pankaj, Webb, Chaille T, Huang, Cheng, Schittenhelm, Ralf B, Beeby, Morgan, Gumbart, J C, Lithgow, Trevor, Hay, Iain D

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New Guinea has the world’s richest island flora von Cámara-Leret, Rodrigo, Frodin, David G., Adema, Frits, Anderson, Christiane, Appelhans, Marc S., Argent, George, Arias Guerrero, Susana, Ashton, Peter, Baker, William J., Barfod, Anders S., Barrington, David, Borosova, Renata, Bramley, Gemma L. C., Briggs, Marie, Buerki, Sven, Cahen, Daniel, Callmander, Martin W., Cheek, Martin, Chen, Cheng-Wei, Conn, Barry J., Coode, Mark J. E., Darbyshire, Iain, Dawson, Sally, Dransfield, John, Drinkell, Clare, Duyfjes, Brigitta, Ebihara, Atsushi, Ezedin, Zacky, Fu, Long-Fei, Gideon, Osia, Girmansyah, Deden, Govaerts, Rafaël, Fortune-Hopkins, Helen, Hassemer, Gustavo, Hay, Alistair, Heatubun, Charlie D., Hind, D. J. Nicholas, Hoch, Peter, Homot, Peter, Hovenkamp, Peter, Hughes, Mark, Jebb, Matthew, Jennings, Laura, Jimbo, Tiberius, Kessler, Michael, Kiew, Ruth, Knapp, Sandra, Lamei, Penniel, Lehnert, Marcus, Lewis, Gwilym P., Linder, Hans Peter, Lindsay, Stuart, Low, Yee Wen, Lucas, Eve, Mancera, Jeffrey P., Monro, Alexandre K., Moore, Alison, Middleton, David J., Nagamasu, Hidetoshi, Newman, Mark F., Nic Lughadha, Eimear, Melo, Pablo H. A., Ohlsen, Daniel J., Pannell, Caroline M., Parris, Barbara, Pearce, Laura, Penneys, Darin S., Perrie, Leon R., Petoe, Peter, Poulsen, Axel Dalberg, Prance, Ghillean T., Quakenbush, J. Peter, Raes, Niels, Rodda, Michele, Rogers, Zachary S., Schuiteman, André, Schwartsburd, Pedro, Scotland, Robert W., Simmons, Mark P., Simpson, David A., Stevens, Peter, Sundue, Michael, Testo, Weston, Trias-Blasi, Anna, Turner, Ian, Utteridge, Timothy, Walsingham, Lesley, Webber, Bruce L., Wei, Ran, Weiblen, George D., Weigend, Maximilian, Weston, Peter, de Wilde, Willem, Wilkie, Peter, Wilmot-Dear, Christine M., Wilson, Hannah P., Wood, John R. I., Zhang, Li-Bing, van Welzen, Peter C.

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Tracking the Emergence of SARS-CoV-2 Alpha Variant in the United Kingdom von Walker, A. Sarah, Vihta, Karina-Doris, Gethings, Owen, Pritchard, Emma, Jones, Joel, House, Thomas, Bell, Iain, Bell, John I, Newton, John N, Farrar, Jeremy, Diamond, Ian, Studley, Ruth, Rourke, Emma, Hay, Jodie, Hopkins, Susan, Crook, Derrick, Peto, Tim, Matthews, Philippa C, Eyre, David W, Stoesser, Nicole, Pouwels, Koen B

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Antibiotic regimen based on population analysis of residing persister cells eradicates Staphylococcus epidermidis biofilms von Yang, Shoufeng, Hay, Iain D., Cameron, David R., Speir, Mary, Cui, Bintao, Su, Feifei, Peleg, Anton Y., Lithgow, Trevor, Deighton, Margaret A., Qu, Yue

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2511: Circulating cell-free HPV DNA correlates with disease volume in p16 positive OPSCC von NOBLE, DAVID, Salati, Victoria, Srinivasan, Devraj P., Mackenzie, Joanna, Adamowicz, Martyna, Robert, Christelle, Carey, Lara M., Cuschieri, Kate, Conn, Brendan, Hay, Ashley, Aitman, Timothy J., Nixon, Iain J.

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Comparison of liquid biopsy to immunohistochemistry and tissue PCR in diagnostic oropharyngeal squamous cell carcinoma von Salati, Victoria, Coote, Abbie, Adamowicz, Martyna, Robert, Christelle, Carey, Lara M., Cuschieri, Kate, Conn, Brendan, Noble, David, Hay, Ashley, Aitman, Timothy J., Nixon, Iain J.

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BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance von Nesic, Ksenija, Krais, John J, Wang, Yifan, Vandenberg, Cassandra J, Patel, Pooja, Cai, Kathy Q, Kwan, Tanya, Lieschke, Elizabeth, Ho, Gwo-Yaw, Barker, Holly E, Bedo, Justin, Casadei, Silvia, Farrell, Andrew, Radke, Marc, Shield-Artin, Kristy, Penington, Jocelyn S, Geissler, Franziska, Kyran, Elizabeth, Betsch, Robert, Xu, Lijun, Zhang, Fan, Dobrovic, Alexander, Olesen, Inger, Kristeleit, Rebecca, Oza, Amit, McNeish, Iain, Ratnayake, Gayanie, Traficante, Nadia, DeFazio, Anna, Bowtell, David D L, Harding, Thomas C, Lin, Kevin, Swisher, Elizabeth M, Kondrashova, Olga, Scott, Clare L, Johnson, Neil, Wakefield, Matthew J

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Clinical management of community-acquired meningitis in adults in the UK and Ireland in 2017: a retrospective cohort study on behalf of the National Infection Trainees Collaborativ... von Harvey, David, Defres, Sylviane, McGill, Fiona, Barrett, Lucinda, Edwards, Frances, McLeod, Mairi, Singh, Ramandeep, Htwe, Su su, Duane, Grace, Vink, Elen, Poyner, Jennifer, Crane, Jenni, Lloyd, Ollie, Chisholm, Emma, Kustos, Ildiko, McEwen, Ruth, Sutton, Sam, Jones, Lewis, Tilley, Robert, Estee Torok, M., Ramsay, Isobel, Ivan, Monica, Ansett, Jennifer, Eshiwe, Celestine, Harris, Stephanie, Larkin, Susan, Kanabar, Shivani, Mutengesa, Ernest, Ling, Mirella, Green, Christopher, Williams, Martin, Griffith, David, Bulteel, Naomi, Milne, Charlotte, Sarma, Jayanta, Urquhart, Lynn, Muir, Alison, White, Leila, Aberdein, Jody, Aziz, Mahmoud, White, Daniel, Weston, Natasha, Fordham, Imogen, Evans, Terry John, Wootton, Louise, Turner, David, Horsley, Ashley, Rosser, Andrew, Norton, Nicholas J, Duxbury, Megan, Deshpande, Ashutosh, Bellhouse, Emilie, Khalsa, Kamaljit, Tanmay, Kanitkar, Dawidziuk, Alexsander, Allen, Joanna, Kelly, Sarah, Adler, Hugh, Ejere, Elshadai, Shah, Aarti, Soo, Yiwen, Beadles, Wendy, Sturgeon, Heather, Ben Tomlinson, David Chadwick, McGoldrick, Claire, McDowell, Katie, Graham, Clive, Molosiwa, Mpho, Hunter, Ewan, Owen, Ruth, Kennedy, Katherine FlackAdrian, Robinson, Amy, Cross, Phoebe, Perry, Fay, Khan, Ali, Selvam, Sarathy, Wong, Jeremy, Pasztor, Monika, Patel, Trupti, Soliman, Basma, Paraiso, Hassan, Smith, Anna, Blanshard, Andrew, Reddy, Harish, Woodhouse, Ken, Coebergh, Jan, Muldoon, Eavan, O’regan, Rhea, Teoh, Tee Keat, Tiberi, Simon, Bell, Caryn RosmarinLucy, Lambourne, Jonathan, McGuire, Emma, Bhide, Ishaan, Sagoo, Karanjeet, Balakrishnan, Indran, Jones, Tim, Patel, Kajal, Faris, Barzo, Singh, Ricky

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Pharmacotherapy, alternative and adjunctive therapies for eating disorders: findings from a rapid review von Rodan, Sarah-Catherine, Bryant, Emma, Le, Anvi, Maloney, Danielle, Touyz, Stephen, McGregor, Iain S, Maguire, Sarah

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Design and optimisation of orally active TLR7 agonists for the treatment of hepatitis C virus infection von Tran, Thien-Duc, Pryde, David C., Jones, Peter, Adam, Fiona M., Benson, Neil, Bish, Gerwyn, Calo, Frederick, Ciaramella, Guiseppe, Dixon, Rachel, Duckworth, Jonathan, Fox, David N.A., Hay, Duncan A., Hitchin, James, Horscroft, Nigel, Howard, Martin, Gardner, Iain, Jones, Hannah M., Laxton, Carl, Parkinson, Tanya, Parsons, Gemma, Proctor, Katie, Smith, Mya C., Smith, Nicholas, Thomas, Amy

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Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled,... von Nicholas I. Paton, Wolfgang Stöhr, Alejandro Arenas-Pinto, Amanda Clarke, Ian Williams, Margaret Johnson, Chloe Orkin, Fabian Chen, Vincent Lee, Alan Winston, Mark Gompels, Julie Fox, Karen Sanders, David T. Dunn, Martin Fisher, Amanda Clarke, Wendy Hadley, David Stacey, Margaret Johnson, Pat Byrne, Ian Williams, Nahum De Esteban, Pierre Pellegrino, Lewis Haddow, Alejandro Arenas-Pinto, Chloe Orkin, James Hand, Carl De Souza, Lisa Murthen, Andrew Crawford-Jones, Fabian Chen, Ruth Wilson, Elizabeth Green, John Masterson, Vincent Lee, Kamlesh Patel, Rebecca Howe, Alan Winston, Scott Mullaney, Mark Gompels, Louise Jennings, Nicholas Beeching, Rebecca Tamaklo, Julie Fox, Alistair Teague, Isabelle Jendrulek, Juan Manuel Tiraboschi, Ed Wilkins, Yvonne Clowes, Andrew Thompson, Gary Brook, Manoj Trivedi, Kazeem Aderogba, Martin Jones, Andrew DeBurgh-Thomas, Liz Jones, Iain Reeves, Sifiso Mguni, David Chadwick, Pauline Spence, Nellie Nkhoma, Zoe Warwick, Suzanne Price, Sally Read, Elbushra Herieka, James Walker, Ruth Woodward, John Day, Laura Hilton, Veerakathy Harinda, Helen Blackman, Phillip Hay, Wendy Mejewska, Olanike Okolo, Edmund Ong, Karen Martin, Lee Munro, David Dockrell, Lynne Smart, Jonathan Ainsworth, Anele Waters, Stephen Kegg, Sara McNamara, Steve Taylor, Gerry Gilleran, Brian Gazzard, Jane Rowlands, Sris Allan, Rumun Sandhu, Nigel O'Farrell, Sheena Quaid, Fabiola Martin, Caroline Bennett, Moses Kapembwa, Jane Minton, James Calderwood, Frank Post, Lucy Campbell, Emily Wandolo, Adrian Palfreeman

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The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile-Part 1 von Tran, Thien Duc, Wakenhut, Florian, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Brimage, Rebecca A., Halstead, Rebecca, Glen, Rebecca, Wilson, Craig P., Adam, Fiona, Hay, Duncan, Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C., Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C.

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The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile-Part 2 von Wakenhut, Florian, Tran, Thien Duc, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Stonehouse, David, Cheung, Kathy, Wybrow, Robert, Daverio, Felice, Crook, Samuel, Statham, Keith, Leese, David, Stead, Darren, Adam, Fiona, Hay, Duncan, Roberts, Lee R., Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C., Goetz, Gilles H., Che, Ye, Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C.

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Design and optimisation of potent gp120-CD4 inhibitors von Tran, Thien-Duc, Adam, Fiona M., Calo, Frederick, Fenwick, David R., Fok-Seang, Juin, Gardner, Iain, Hay, Duncan A., Perros, Manos, Rawal, Jaiessh, Middleton, Donald S., Parkinson, Tanya, Pickford, Christopher, Platts, Michelle, Randall, Amy, Stephenson, Peter T., Vuong, Hannah, Williams, David H.

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The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile--Part2 von Wakenhut, Florian, Tran, Thien Duc, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Stonehouse, David, Cheung, Kathy, Wybrow, Robert, Daverio, Felice, Crook, Samuel, Statham, Keith, Leese, David, Stead, Darren, Adam, Fiona, Hay, Duncan, Roberts, Lee R, Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C, Goetz, Gilles H, Che, Ye, Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C

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The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile--Part1 von Tran, Thien Duc, Wakenhut, Florian, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Brimage, Rebecca A, Halstead, Rebecca, Glen, Rebecca, Wilson, Craig P, Adam, Fiona, Hay, Duncan, Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C, Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C

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Discovery of a small molecule inhibitor through interference with the gp120–CD4 interaction von Williams, David H., Adam, Fiona, Fenwick, David R., Fok-Seang, Juin, Gardner, Iain, Hay, Duncan, Jaiessh, Rawal, Middleton, Donald S., Mowbray, Charles E., Parkinson, Tanya, Perros, Manos, Pickford, Christopher, Platts, Michelle, Randall, Amy, Siddle, Daniel, Stephenson, Peter T., Tran, Thien-Duc, Vuong, Hannah

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Concurrent Oral 11 – Osteoarthritis [OP73–OP78] von Burleigh, Annika, Saklatvala, Jeremy, Vincent, Tonia L., Sowden, Evin, Kynaston, David, Rai, Madhurima, Yates, Elliot, Kim, Winston, Freemont, Anthony, White, Kirsten M., Soni, Anushka, Kiran, Amit, Goulston, Lyndsey M., Hart, Deborah J., Spector, Tim D., Javaid, Kassim, Arden, Nigel K., Duncan, Rachel, Peat, George, Thomas, Elaine, Hay, Elaine, Croft, Peter, Abraham, Ajay, Goff, Iain, Pearce, Mark S., Francis, Roger M., Birrell, Fraser, Palmer, Shea, Domaille, Melissa, Cramp, Fiona, Johnson, Mark I.

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