CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses von Hammitzsch, Ariane, Tallant, Cynthia, Fedorov, Oleg, O’Mahony, Alison, Brennan, Paul E., Hay, Duncan A., Martinez, Fernando O., Al-Mossawi, M. Hussein, de Wit, Jelle, Vecellio, Matteo, Wells, Christopher, Wordsworth, Paul, Müller, Susanne, Knapp, Stefan, Bowness, Paul

Volltext

Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains von Hay, Duncan A, Fedorov, Oleg, Martin, Sarah, Singleton, Dean C, Tallant, Cynthia, Wells, Christopher, Picaud, Sarah, Philpott, Martin, Monteiro, Octovia P, Rogers, Catherine M, Conway, Stuart J, Rooney, Timothy P. C, Tumber, Anthony, Yapp, Clarence, Filippakopoulos, Panagis, Bunnage, Mark E, Müller, Susanne, Knapp, Stefan, Schofield, Christopher J, Brennan, Paul E

Volltext

Progress in the Development and Application of Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions von Hewings, David S, Rooney, Timothy P. C, Jennings, Laura E, Hay, Duncan A, Schofield, Christopher J, Brennan, Paul E, Knapp, Stefan, Conway, Stuart J

Volltext

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy von Picaud, Sarah, Fedorov, Oleg, Thanasopoulou, Angeliki, Leonards, Katharina, Jones, Katherine, Meier, Julia, Olzscha, Heidi, Monteiro, Octovia, Martin, Sarah, Philpott, Martin, Tumber, Anthony, Filippakopoulos, Panagis, Yapp, Clarence, Wells, Christopher, Che, Ka Hing, Bannister, Andrew, Robson, Samuel, Kumar, Umesh, Parr, Nigel, Lee, Kevin, Lugo, Dave, Jeffrey, Philip, Taylor, Simon, Vecellio, Matteo L, Bountra, Chas, Brennan, Paul E, O'Mahony, Alison, Velichko, Sharlene, Müller, Susanne, Hay, Duncan, Daniels, Danette L, Urh, Marjeta, La Thangue, Nicholas B, Kouzarides, Tony, Prinjha, Rab, Schwaller, Jürg, Knapp, Stefan

Volltext

Optimisation of a novel series of ENaC inhibitors, leading to the selection of the long-acting inhaled clinical candidate ETD001, a potential new treatment for cystic fibrosis von Danahay, Henry, Gosling, Martin, Fox, Roy, Lilley, Sarah, Charlton, Holly, Hargrave, Jonathan D., Schofield, Thomas B., Hay, Duncan A., Went, Naomi, McMahon, Pearl, Marlin, Frederic, Scott, John, Vile, Julia, Hewison, Steve, Ellam, Sarah, Brown, Samantha, Sabater, Juan, Kennet, Guy, Lightowler, Sean, Collingwood, Stephen P.

Volltext

Fish navigation of large dams emerges from their modulation of flow field experience von Goodwin, R. Andrew, Politano, Marcela, Garvin, Justin W., Nestler, John M., Hay, Duncan, Anderson, James J., Weber, Larry J., Dimperio, Eric, Smith, David L., Timko, Mark

Volltext

A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation-π Interaction von Rooney, Timothy P. C., Filippakopoulos, Panagis, Fedorov, Oleg, Picaud, Sarah, Cortopassi, Wilian A., Hay, Duncan A., Martin, Sarah, Tumber, Anthony, Rogers, Catherine M., Philpott, Martin, Wang, Minghua, Thompson, Amber L., Heightman, Tom D., Pryde, David C., Cook, Andrew, Paton, Robert S., Müller, Susanne, Knapp, Stefan, Brennan, Paul E., Conway, Stuart J.

Volltext

Structure-Based Design of Highly Selective Inhibitors of the CREB Binding Protein Bromodomain von Denny, R. Aldrin, Flick, Andrew C, Coe, Jotham, Langille, Jonathan, Basak, Arindrajit, Liu, Shenping, Stock, Ingrid, Sahasrabudhe, Parag, Bonin, Paul, Hay, Duncan A, Brennan, Paul E, Pletcher, Mathew, Jones, Lyn H, Chekler, Eugene L. Piatnitski

Volltext

Seeing culture from below: Counter‐curating, counter‐ethnography, counter‐mapping von Grindon, Gavin, Hay, Duncan

Volltext

Zircon alteration, formation and preservation in sandstones von HAY, DUNCAN C, DEMPSTER, TIM J

Volltext

Chemical probes and inhibitors of bromodomains outside the BET family von Moustakim, Moses, Clark, Peter G K, Hay, Duncan A, Dixon, Darren J, Brennan, Paul E

Volltext

Anatomy of a low temperature zircon outgrowth von Hay, Duncan C., Dempster, Tim J., Lee, Martin R., Brown, David J.

Volltext

Property rights, institutional regime shifts and the provision of freshwater ecosystem services on the Pongola River floodplain, South Africa von Nkhata, Bimo Abraham, Breen, Charles, Hay, Duncan, Wilkinson, Melanie

Volltext

Alkali-metal mediated zincation of N-heterocyclic substrates using the lithium zincate complex, (THF)Li(TMP)Zn( tBu) 2 and applications in in situ cross coupling reactions von Blair, Victoria L., Blakemore, David C., Hay, Duncan, Hevia, Eva, Pryde, David C.

Volltext

The Identification of Potential Resilient Estuary-based Enterprises to Encourage Economic Empowerment in South Africa: a Toolkit Approach von Bowd, Rebecca, Quinn, Nevil, Kotze, Donovan C., Hay, Duncan G., Mander, Myles

Volltext

Design and optimisation of orally active TLR7 agonists for the treatment of hepatitis C virus infection von Tran, Thien-Duc, Pryde, David C., Jones, Peter, Adam, Fiona M., Benson, Neil, Bish, Gerwyn, Calo, Frederick, Ciaramella, Guiseppe, Dixon, Rachel, Duckworth, Jonathan, Fox, David N.A., Hay, Duncan A., Hitchin, James, Horscroft, Nigel, Howard, Martin, Gardner, Iain, Jones, Hannah M., Laxton, Carl, Parkinson, Tanya, Parsons, Gemma, Proctor, Katie, Smith, Mya C., Smith, Nicholas, Thomas, Amy

Volltext

Discovery of a highly potent series of TLR7 agonists von Jones, Peter, Pryde, David C., Tran, Thien-Duc, Adam, Fiona M., Bish, Gerwyn, Calo, Frederick, Ciaramella, Guiseppe, Dixon, Rachel, Duckworth, Jonathan, Fox, David N.A., Hay, Duncan A., Hitchin, James, Horscroft, Nigel, Howard, Martin, Laxton, Carl, Parkinson, Tanya, Parsons, Gemma, Proctor, Katie, Smith, Mya C., Smith, Nicholas, Thomas, Amy

Volltext

Characterizing firefighter's exposure to over 130 SVOCs using silicone wristbands: A pilot study comparing on-duty and off-duty exposures von Levasseur, Jessica L., Hoffman, Kate, Herkert, Nicholas J., Cooper, Ellen, Hay, Duncan, Stapleton, Heather M.

Volltext

A flexible synthesis of C-6 and N-1 analogues of a 4-amino-1,3-dihydroimidazo[4,5- c]pyridin-2-one core von Hay, Duncan A., Adam, Fiona M., Bish, Gerwyn, Calo, Frederick, Dixon, Rachel, Fray, M. Jonathan, Hitchin, James, Jones, Peter, Paradowski, Michael, Parsons, Gemma C., Proctor, Katie J.W., Pryde, David C., Smith, Nicholas N., Tran, Thien-Duc

Volltext

Design and optimisation of potent gp120-CD4 inhibitors von Tran, Thien-Duc, Adam, Fiona M., Calo, Frederick, Fenwick, David R., Fok-Seang, Juin, Gardner, Iain, Hay, Duncan A., Perros, Manos, Rawal, Jaiessh, Middleton, Donald S., Parkinson, Tanya, Pickford, Christopher, Platts, Michelle, Randall, Amy, Stephenson, Peter T., Vuong, Hannah, Williams, David H.

Volltext