2024 Recommendations for Preventive Pediatric Health Care: Policy Statement von Hackell, Jesse M., Almendarez, Yvette M., Cantrell, Patricia E., Cleary, Carolyn, Hawse, Elizabeth, Kafer, Lisa M., Kaplan, Seth D., Latimer, Tomitra, Skatrud, Alisa, Wiskind, Robert H., Magnus, Mackenzie, Cooney, Maureen, Kemper, Alex R., Warner, Robin, Barone, Lauren

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Optimized immunohistochemical detection of estrogen receptor beta using two validated monoclonal antibodies confirms its expression in normal and malignant breast tissues von Hawse, John R., Carter, Jodi M., Aspros, Kirsten G. M., Bruinsma, Elizabeth S., Koepplin, Justin W., Negron, Vivian, Subramaniam, Malayannan, Ingle, James N., Rech, Karen L., Goetz, Matthew P.

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TIEG and estrogen modulate SOST expression in the murine skeleton von Subramaniam, Malayannan, Pitel, Kevin S., Bruinsma, Elizabeth S., Monroe, David G., Hawse, John R.

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ERβ-mediated induction of cystatins results in suppression of TGFβ signaling and inhibition of triple-negative breast cancer metastasis von Reese, Jordan M., Bruinsma, Elizabeth S., Nelson, Adam W., Chernukhin, Igor, Carroll, Jason S., Li, Ying, Subramaniam, Malayannan, Suman, Vera J., Negron, Vivian, Monroe, David G., Ingle, James N., Goetz, Matthew P., Hawse, John R.

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A TGF-β/KLF10 signaling axis regulates atrophy-associated genes to induce muscle wasting in pancreatic cancer von Dasgupta, Aneesha, Gibbard, Daniel F, Schmitt, Rebecca E, Arneson-Wissink, Paige C, Ducharme, Alexandra M, Bruinsma, Elizabeth S, Hawse, John R, Jatoi, Aminah, Doles, Jason D

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Structure study reveals active and inactive conformations of protein kinase C B1 von Cong, Anh T.Q., Witter, Taylor L., Elizabeth, Bruinsma S., Jayaraman, Swaathi, Dugan, Maria, Hawse, John R., Goetz, Matthew P., Schellenberg, Matthew J.

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Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer von Jayaraman, Swaathi, Hou, Xiaonan, Kuffel, Mary J, Suman, Vera J, Hoskin, Tanya L, Reinicke, Kathryn E, Monroe, David G, Kalari, Krishna R, Tang, Xiaojia, Zeldenrust, Megan A, Cheng, Jingfei, Bruinsma, Elizabeth S, Buhrow, Sarah A, McGovern, Renee M, Safgren, Stephanie L, Walden, Chad A, Carter, Jodi M, Reid, Joel M, Ingle, James N, Ames, Matthew M, Hawse, John R, Goetz, Matthew P

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Peptide Modulation of Class I Major Histocompatibility Complex Protein Molecular Flexibility and the Implications for Immune Recognition von Hawse, William F., Gloor, Brian E., Ayres, Cory M., Kho, Kevin, Nuter, Elizabeth, Baker, Brian M.

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TIEG1/KLF10 modulates Runx2 expression and activity in osteoblasts von Hawse, John R, Cicek, Muzaffer, Grygo, Sarah B, Bruinsma, Elizabeth S, Rajamannan, Nalini M, van Wijnen, Andre J, Lian, Jane B, Stein, Gary S, Oursler, Merry Jo, Subramaniam, Malayannan, Spelsberg, Thomas C

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Development and Characterization of Novel Endoxifen-Resistant Breast Cancer Cell Lines Highlight Numerous Differences from Tamoxifen-Resistant Models von Jones, Calley J, Subramaniam, Malayannan, Emch, Michael J, Bruinsma, Elizabeth S, Ingle, James N, Goetz, Matthew P, Hawse, John R

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ERβ inhibits cyclin dependent kinases 1 and 7 in triple negative breast cancer von Reese, Jordan M, Bruinsma, Elizabeth S, Monroe, David G, Negron, Vivian, Suman, Vera J, Ingle, James N, Goetz, Matthew P, Hawse, John R

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Endoxifen downregulates AKT phosphorylation through protein kinase C beta 1 inhibition in ERα+ breast cancer von Jayaraman, Swaathi, Wu, Xinyan, Kalari, Krishna R., Tang, Xiaojia, Kuffel, Mary J., Bruinsma, Elizabeth S., Jalali, Shahrzad, Peterson, Kevin L., Correia, Cristina, Kudgus, Rachel A., Kaufmann, Scott H., Renuse, Santosh, Ingle, James N., Reid, Joel M., Ames, Matthew M., Fields, Alan P., Schellenberg, Matthew J., Hawse, John R., Pandey, Akhilesh, Goetz, Matthew P.

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TIEG1 modulates β-catenin sub-cellular localization and enhances Wnt signaling in bone von Subramaniam, Malayannan, Cicek, Muzaffer, Pitel, Kevin S, Bruinsma, Elizabeth S, Nelson Holte, Molly H, Withers, Sarah G, Rajamannan, Nalini M, Secreto, Frank J, Venuprasad, K, Hawse, John R

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Abstract P6-05-10: CUDC-101 enhances estrogen-mediated anticancer effects in ERβ+ TNBC von Emch, Michael Justin, Benjamin, David, Bruinsma, Elizabeth, Nelson-Holte, Molly, Goetz, Matthew, Hawse, John

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Novel role of Tieg1 in muscle metabolism and mitochondrial oxidative capacities von Kammoun, Malek, Piquereau, Jerome, Nadal‐Desbarats, Lydie, Même, Sandra, Beuvin, Maud, Bonne, Gisèle, Veksler, Vladimir, Le Fur, Yann, Pouletaut, Philippe, Même, William, Szeremeta, Frederic, Constans, Jean‐Marc, Bruinsma, Elizabeth S., Nelson Holte, Molly H., Najafova, Zeynab, Johnsen, Steven A., Subramaniam, Malayannan, Hawse, John R., Bensamoun, Sabine F.

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Abstract P4-02-09: The lncRNA XIST mediates sensitivity to ERβ targeted therapies in triple negative breast cancer von Emch, Michael J, Aspros, Kirsten GM, Bruinsma, Elizabeth S, Kalari, Krishna R, Jones, Calley J, Simone, Brandon W, Goetz, Matthew P, Hawse, John R

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Histone demethylase JARID1B/KDM5B is a corepressor of TIEG1/KLF10 von Kim, Joanna, Shin, Sook, Subramaniam, Malayannan, Bruinsma, Elizabeth, Kim, Tae-Dong, Hawse, John R., Spelsberg, Thomas C., Janknecht, Ralf

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Abstract LB078: Hexyl-(cuban-1-yl-methyl)-biguanide (HCB) inhibits hormone therapy resistant breast cancer cells, in part by Inhibiting CYP3A4 arachidonic acid epoxygenase activity von Guo, Zhijun, Lei, Jianxun, Hong, Kwon Ho, Norris, Beverly, Flory, Craig M., Jayaraman, Swaathi, McDermott, Connor, Ambrose, Elizabeth, Sevrioukova, Irina, Poulos, Tom, Denisov, Ilia, Sliga, Stephen, Schumacher, Robert J., Georg, Gunda I., Hawse, John R., Goetz, Matthew P., Potter, David A.

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Abstract P6-04-06: Protein kinase C beta 1 (PKCβ1), a novel drug target of Z-endoxifen, inhibits growth of estrogen receptor positive (ER+) breast cancer via activation of the NF-k... von Jayaraman, Swaathi, Kuffel, Mary J, Kalari, Krishna R, Thompson, Kevin J, Tang, Xiaojia, Bruinsma, Elizabeth S, Hawse, John R, Goetz, Matthew P

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Abstract PD8-04: Antitumor activity of Z-endoxifen (ENDX) is mediated via PKCβ1-dependent ERα loss and cell cycle arrest in ERα-positive breast cancer von Jayaraman, Swaathi, Kuffel, Mary J, Kalari, Krishna R, Thompson, Kevin J, Tang, Xiaojia, Suman, Vera J, Bruinsma, Elizabeth S, O'Sullivan, Ciara C, Wang, Liewei, Weinshilboum, Richard, Ingle, James N, Hawse, John R, Goetz, Matthew P

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