Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2 von Tencer, Adam H., Yu, Yucong, Causse, Sebastien Z., Campbell, Grant R., Klein, Brianna J., Xuan, Hongwen, Cartier, Jessy, Miles, Mark A., Gaurav, Nitika, Zadoroznyj, Aymeric, Holt, Tina A., Wen, Hong, Hawkins, Christine J., Spector, Stephen A., Dubrez, Laurence, Shi, Xiaobing, Kutateladze, Tatiana G.

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Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine von Miles, Mark A, Hawkins, Christine J

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Establishment and Characterisation of Metastatic Extraskeletal Ewing Sarcoma Mouse Models von Cerra, Carmelo, Harris, Michael A., Hawkins, Christine J.

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Mutagenic assessment of chemotherapy and Smac mimetic drugs in cells with defective DNA damage response pathways von Miles, Mark A., Hawkins, Christine J.

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Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly von Atkin-Smith, Georgia K., Miles, Mark A., Tixeira, Rochelle, Lay, Fung T., Duan, Mubing, Hawkins, Christine J., Phan, Thanh Kha, Paone, Stephanie, Mathivanan, Suresh, Hulett, Mark D., Chen, Weisan, Poon, Ivan K.H.

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In vitro analysis reveals necroptotic signaling does not provoke DNA damage or HPRT mutations von Miles, Mark A., Hawkins, Christine J.

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Smac mimetics LCL161 and GDC-0152 inhibit osteosarcoma growth and metastasis in mice von Shekhar, Tanmay M, Burvenich, Ingrid J G, Harris, Michael A, Rigopoulos, Angela, Zanker, Damien, Spurling, Alex, Parker, Belinda S, Walkley, Carl R, Scott, Andrew M, Hawkins, Christine J

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Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax von Fletcher, Jamie I, Meusburger, Sarina, Hawkins, Christine J, Riglar, David T, Lee, Erinna F, Fairlie, W. Douglas, Huang, David C.S, Adams, Jerry M

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Proteasome inhibitors trigger mutations via activation of caspases and CAD, but mutagenesis provoked by the HDAC inhibitors vorinostat and romidepsin is caspase/CAD-independent von Miles, Mark A., Harris, Michael A., Hawkins, Christine J.

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SfDronc, an initiator caspase involved in apoptosis in the fall armyworm Spodoptera frugiperda von Huang, Ning, Civciristov, Srgjan, Hawkins, Christine J., Clem, Rollie J.

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The N Terminus of the Vaccinia Virus Protein F1L Is an Intrinsically Unstructured Region That Is Not Involved in Apoptosis Regulation von Caria, Sofia, Marshall, Bevan, Burton, Robyn-Lee, Campbell, Stephanie, Pantaki-Eimany, Delara, Hawkins, Christine J., Barry, Michele, Kvansakul, Marc

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Modeling Metazoan Apoptotic Pathways in Yeast von Bloomer, David T., Kitevska, Tanja, Brand, Ingo L., Jabbour, Anissa M., Nguyen, Hang, Hawkins, Christine J.

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Hsp72 Inhibits Apoptosis Upstream of the Mitochondria and Not through Interactions with Apaf-1 von Steel, Rohan, Doherty, Judith P., Buzzard, Katherine, Clemons, Nicholas, Hawkins, Christine J., Anderson, Robin L.

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Apaf-1 and Caspase-9 Accelerate Apoptosis, but Do Not Determine Whether Factor-Deprived or Drug-Treated Cells Die von Ekert, Paul G., Read, Stuart H., Silke, John, Marsden, Vanessa S., Kaufmann, Hitto, Hawkins, Christine J., Gerl, Robert, Kumar, Sharad, Vaux, David L.

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Caspase inhibitors of the P35 family are more active when purified from yeast than bacteria von Brand, Ingo L, Civciristov, Srgjan, Taylor, Nicole L, Talbo, Gert H, Pantaki-Eimany, Delara, Levina, Vita, Clem, Rollie J, Perugini, Matthew A, Kvansakul, Marc, Hawkins, Christine J

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Transient NK Cell Depletion Facilitates Pulmonary Osteosarcoma Metastases After Intravenous Inoculation in Athymic Mice von Harris, Michael A., Shekhar, Tanmay M., Coupland, Lucy A., Miles, Mark A., Hawkins, Christine J.

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DIABLO Promotes Apoptosis by Removing MIHA/XIAP from Processed Caspase 9 von Ekert, Paul G., Silke, John, Hawkins, Christine J., Verhagen, Anne M., Vaux, David L.

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Mature DIABLO/Smac is produced by the IMP protease complex on the mitochondrial inner membrane von Burri, Lena, Strahm, Yvan, Hawkins, Christine J, Gentle, Ian E, Puryer, Michelle A, Verhagen, Anne, Callus, Bernard, Vaux, David, Lithgow, Trevor

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Caspase-2: controversial killer or checkpoint controller von Kitevska, Tanja, Spencer, Damian M. S, Hawkins, Christine J

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Data on the DNA damaging and mutagenic potential of the BH3-mimetics ABT-263/Navitoclax and TW-37 von Green, Maja M., Shekhar, Tanmay M., Hawkins, Christine J.

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