Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis von Vartanian, Steffan, Ma, Taylur P., Lee, James, Haverty, Peter M., Kirkpatrick, Donald S., Yu, Kebing, Stokoe, David

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Genomic Analysis of Smoothened Inhibitor Resistance in Basal Cell Carcinoma von Sharpe, Hayley J., Pau, Gregoire, Dijkgraaf, Gerrit J., Basset-Seguin, Nicole, Modrusan, Zora, Januario, Thomas, Tsui, Vickie, Durham, Alison B., Dlugosz, Andrzej A., Haverty, Peter M., Bourgon, Richard, Tang, Jean Y., Sarin, Kavita Y., Dirix, Luc, Fisher, David C., Rudin, Charles M., Sofen, Howard, Migden, Michael R., Yauch, Robert L., de Sauvage, Frederic J.

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Transposable element expression in tumors is associated with immune infiltration and increased antigenicity von Kong, Yu, Rose, Christopher M., Cass, Ashley A., Williams, Alexander G., Darwish, Martine, Lianoglou, Steve, Haverty, Peter M., Tong, Ann-Jay, Blanchette, Craig, Albert, Matthew L., Mellman, Ira, Bourgon, Richard, Greally, John, Jhunjhunwala, Suchit, Chen-Harris, Haiyin

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Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation von Raisner, Ryan, Kharbanda, Samir, Jin, Lingyan, Jeng, Edwin, Chan, Emily, Merchant, Mark, Haverty, Peter M., Bainer, Russell, Cheung, Tommy, Arnott, David, Flynn, E. Megan, Romero, F. Anthony, Magnuson, Steven, Gascoigne, Karen E.

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Super-enhancer acquisition drives oncogene expression in triple negative breast cancer von Raisner, Ryan, Bainer, Russell, Haverty, Peter M, Benedetti, Kelli L, Gascoigne, Karen E

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Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration von Lim, Yoong Wearn, Chen-Harris, Haiyin, Mayba, Oleg, Lianoglou, Steve, Wuster, Arthur, Bhangale, Tushar, Khan, Zia, Mariathasan, Sanjeev, Daemen, Anneleen, Reeder, Jens, Haverty, Peter M., Forrest, William F., Brauer, Matthew, Mellman, Ira, Albert, Matthew L.

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Proline Starvation Induces Unresolved ER Stress and Hinders mTORC1-Dependent Tumorigenesis von Sahu, Nisebita, Dela Cruz, Darlene, Gao, Min, Sandoval, Wendy, Haverty, Peter M., Liu, Jinfeng, Stephan, Jean-Philippe, Haley, Benjamin, Classon, Marie, Hatzivassiliou, Georgia, Settleman, Jeff

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Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer von Jin, Lingyan, Garcia, Jesse, Chan, Emily, de la Cruz, Cecile, Segal, Ehud, Merchant, Mark, Kharbanda, Samir, Raisner, Ryan, Haverty, Peter M, Modrusan, Zora, Ly, Justin, Choo, Edna, Kaufman, Susan, Beresini, Maureen H, Romero, F Anthony, Magnuson, Steven, Gascoigne, Karen E

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Diverse somatic mutation patterns and pathway alterations in human cancers von Kan, Zhengyan, Jaiswal, Bijay S., Stinson, Jeremy, Janakiraman, Vasantharajan, Bhatt, Deepali, Stern, Howard M., Yue, Peng, Haverty, Peter M., Bourgon, Richard, Zheng, Jianbiao, Moorhead, Martin, Chaudhuri, Subhra, Tomsho, Lynn P., Peters, Brock A., Pujara, Kanan, Cordes, Shaun, Davis, David P., Carlton, Victoria E. H., Yuan, Wenlin, Li, Li, Wang, Weiru, Eigenbrot, Charles, Kaminker, Joshua S., Eberhard, David A., Waring, Paul, Schuster, Stephan C., Modrusan, Zora, Zhang, Zemin, Stokoe, David, de Sauvage, Frederic J., Faham, Malek, Seshagiri, Somasekar

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Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes von LEE, Genee Y, HAVERTY, Peter M, DAVIS, David, STOKOE, David, SETTLEMAN, Jeffrey, DE SAUVAGE, Frederic J, NEVE, Richard M, LI LI, KLJAVIN, Noelyn M, BOURGON, Richard, LEE, James, STERN, Howard, MODRUSAN, Zora, SESHAGIRI, Somasekar, ZEMIN ZHANG

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Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors von Merchant, Mark, Moffat, John, Schaefer, Gabriele, Chan, Jocelyn, Wang, Xi, Orr, Christine, Cheng, Jason, Hunsaker, Thomas, Shao, Lily, Wang, Stephanie J, Wagle, Marie-Claire, Lin, Eva, Haverty, Peter M, Shahidi-Latham, Sheerin, Ngu, Hai, Solon, Margaret, Eastham-Anderson, Jeffrey, Koeppen, Hartmut, Huang, Shih-Min A, Schwarz, Jacob, Belvin, Marcia, Kirouac, Daniel, Junttila, Melissa R

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The mutation spectrum revealed by paired genome sequences from a lung cancer patient von Lee, William, Jiang, Zhaoshi, Liu, Jinfeng, Haverty, Peter M., Guan, Yinghui, Stinson, Jeremy, Yue, Peng, Zhang, Yan, Pant, Krishna P., Bhatt, Deepali, Ha, Connie, Johnson, Stephanie, Kennemer, Michael I., Mohan, Sankar, Nazarenko, Igor, Watanabe, Colin, Sparks, Andrew B., Shames, David S., Gentleman, Robert, de Sauvage, Frederic J., Stern, Howard, Pandita, Ajay, Ballinger, Dennis G., Drmanac, Radoje, Modrusan, Zora, Seshagiri, Somasekar, Zhang, Zemin

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Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells von Ong, Christy C, Jubb, Adrian M, Haverty, Peter M, Zhou, Wei, Tran, Victoria, Truong, Tom, Turley, Helen, O'Brien, Tom, Vucic, Domagoj, Harris, Adrian L, Belvin, Marcia, Friedman, Lori S, Blackwood, Elizabeth M, Koeppen, Hartmut, Hoeflich, Klaus P

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ERK inhibition overcomes acquired resistance to MEK inhibitors von Hatzivassiliou, Georgia, Liu, Bonnie, O'Brien, Carol, Spoerke, Jill M, Hoeflich, Klaus P, Haverty, Peter M, Soriano, Robert, Forrest, William F, Heldens, Sherry, Chen, Huifen, Toy, Karen, Ha, Connie, Zhou, Wei, Song, Kyung, Friedman, Lori S, Amler, Lukas C, Hampton, Garret M, Moffat, John, Belvin, Marcia, Lackner, Mark R

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Multiple-gene targeting and mismatch tolerance can confound analysis of genome-wide pooled CRISPR screens von Fortin, Jean-Philippe, Tan, Jenille, Gascoigne, Karen E, Haverty, Peter M, Forrest, William F, Costa, Michael R, Martin, Scott E

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Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer von Liu, Jinfeng, McCleland, Mark, Stawiski, Eric W., Gnad, Florian, Mayba, Oleg, Haverty, Peter M., Durinck, Steffen, Chen, Ying-Jiun, Klijn, Christiaan, Jhunjhunwala, Suchit, Lawrence, Michael, Liu, Hanbin, Wan, Yinan, Chopra, Vivek, Yaylaoglu, Murat B., Yuan, Wenlin, Ha, Connie, Gilbert, Houston N., Reeder, Jens, Pau, Gregoire, Stinson, Jeremy, Stern, Howard M., Manning, Gerard, Wu, Thomas D., Neve, Richard M., de Sauvage, Frederic J., Modrusan, Zora, Seshagiri, Somasekar, Firestein, Ron, Zhang, Zemin

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Loss of NAPRT1 Expression by Tumor-Specific Promoter Methylation Provides a Novel Predictive Biomarker for NAMPT Inhibitors von SHAMES, David S, ELKINS, Kristi, XIAORONG LIANG, YAUCH, Robert L, O'BRIEN, Thomas, BOURGON, Richard, KOEPPEN, Hartmut, BELMONT, Lisa D, WALTER, Kimberly, HOLCOMB, Thomas, PAN DU, MOHL, Dane, YANG XIAO, PHAM, Thinh, HAVERTY, Peter M, LIEDERER, Bianca

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A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types von Wagle, Marie-Claire, Kirouac, Daniel, Klijn, Christiaan, Liu, Bonnie, Mahajan, Shilpi, Junttila, Melissa, Moffat, John, Merchant, Mark, Huw, Ling, Wongchenko, Matthew, Okrah, Kwame, Srinivasan, Shrividhya, Mounir, Zineb, Sumiyoshi, Teiko, Haverty, Peter M., Yauch, Robert L., Yan, Yibing, Kabbarah, Omar, Hampton, Garret, Amler, Lukas, Ramanujan, Saroja, Lackner, Mark R., Huang, Shih-Min A.

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Genetic Alterations and Oncogenic Pathways Associated with Breast Cancer Subtypes von Hu, Xiaolan, Stern, Howard M, Ge, Lin, O'Brien, Carol, Haydu, Lauren, Honchell, Cynthia D, Haverty, Peter M, Peters, Brock A, Wu, Thomas D, Amler, Lukas C, Chant, John, Stokoe, David, Lackner, Mark R, Cavet, Guy

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Human biosample authentication using the high-throughput, cost-effective SNPtrace(TM) system von Liang-Chu, May M Y, Yu, Mamie, Haverty, Peter M, Koeman, Julie, Ziegle, Janet, Lee, Marie, Bourgon, Richard, Neve, Richard M

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