Directed migration of mesenchymal cells: where signaling and the cytoskeleton meet von Bear, James E, Haugh, Jason M

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Profilin-1 Serves as a Gatekeeper for Actin Assembly by Arp2/3-Dependent and -Independent Pathways von Rotty, Jeremy D., Wu, Congying, Haynes, Elizabeth M., Suarez, Cristian, Winkelman, Jonathan D., Johnson, Heath E., Haugh, Jason M., Kovar, David R., Bear, James E.

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Live-Cell Fluorescence Microscopy with Molecular Biosensors: What Are We Really Measuring? von Haugh, Jason M.

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F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling von Johnson, Heath E, King, Samantha J, Asokan, Sreeja B, Rotty, Jeremy D, Bear, James E, Haugh, Jason M

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Mesenchymal Chemotaxis Requires Selective Inactivation of Myosin II at the Leading Edge via a Noncanonical PLCγ/PKCα Pathway von Asokan, Sreeja B., Johnson, Heath E., Rahman, Anisur, King, Samantha J., Rotty, Jeremy D., Lebedeva, Irina P., Haugh, Jason M., Bear, James E.

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Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism von Welf, Erik S, Ahmed, Shoeb, Johnson, Heath E, Melvin, Adam T, Haugh, Jason M

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Systematic Quantification of Negative Feedback Mechanisms in the Extracellular Signal-regulated Kinase (ERK) Signaling Network von Cirit, Murat, Wang, Chun-Chao, Haugh, Jason M.

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Are Filopodia Privileged Signaling Structures in Migrating Cells? von Johnson, Heath E., Haugh, Jason M.

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Mechanistic models of PLC/PKC signaling implicate phosphatidic acid as a key amplifier of chemotactic gradient sensing von Nosbisch, Jamie L, Rahman, Anisur, Mohan, Krithika, Elston, Timothy C, Bear, James E, Haugh, Jason M

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Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase von Buhrman, Greg, Kumar, V. S. Senthil, Cirit, Murat, Haugh, Jason M., Mattos, Carla

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Bidirectional coupling between integrin-mediated signaling and actomyosin mechanics explains matrix-dependent intermittency of leading-edge motility von Welf, Erik S, Johnson, Heath E, Haugh, Jason M

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Deactivation of a Negative Regulator: A Distinct Signal Transduction Mechanism, Pronounced in Akt Signaling von Rahman, Anisur, Haugh, Jason M.

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Systemic perturbation of the ERK signaling pathway by the proteasome inhibitor, MG132 von Cirit, Murat, Grant, Kyle G, Haugh, Jason M

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Data-driven modelling of receptor tyrosine kinase signalling networks quantifies receptor-specific potencies of PI3K- and Ras-dependent ERK activation von Cirit, Murat, Haugh, Jason M

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Data‐driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states von Ahmed, Shoeb, Grant, Kyle G, Edwards, Laura E, Rahman, Anisur, Cirit, Murat, Goshe, Michael B, Haugh, Jason M

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Fibroblast Migration Is Regulated by Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Protein von Ott, Laura E, Sung, Eui Jae, Melvin, Adam T, Sheats, Mary K, Haugh, Jason M, Adler, Kenneth B, Jones, Samuel L

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Stochastic model of integrin-mediated signaling and adhesion dynamics at the leading edges of migrating cells von Cirit, Murat, Krajcovic, Matej, Choi, Colin K, Welf, Erik S, Horwitz, Alan F, Haugh, Jason M

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Quantitative elucidation of a distinct spatial gradient-sensing mechanism in fibroblasts von Schneider, Ian C, Haugh, Jason M

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Spatial Sensing in Fibroblasts Mediated by 3′ Phosphoinositides von Haugh, Jason M., Codazzi, Franca, Teruel, Mary, Meyer, Tobias

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On the inference of ERK signaling dynamics from protein biosensor measurements von Rahman, Shah Md Toufiqur, Haugh, Jason M

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