Recent Advances in Selective and Irreversible Covalent Ligand Development and Validation von Zhang, Tinghu, Hatcher, John M., Teng, Mingxing, Gray, Nathanael S., Kostic, Milka

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Crystal structure of human IRAK1 von Wang, Li, Qiao, Qi, Ferrao, Ryan, Shen, Chen, Hatcher, John M., Buhrlage, Sara J., Gray, Nathanael S., Wu, Hao

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Passing the Torch von Hatcher, John

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SRPKIN-1: A Covalent SRPK1/2 Inhibitor that Potently Converts VEGF from Pro-angiogenic to Anti-angiogenic Isoform von Hatcher, John M., Wu, Guowei, Zeng, Chuyue, Zhu, Jie, Meng, Fan, Patel, Sherrina, Wang, Wenqiu, Ficarro, Scott B., Leggett, Alan L., Powell, Chelsea E., Marto, Jarrod A., Zhang, Kang, Ki Ngo, Jacky Chi, Fu, Xiang-Dong, Zhang, Tinghu, Gray, Nathanael S.

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Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth von Fontán, Lorena, Qiao, Qi, Hatcher, John M, Casalena, Gabriella, Us, Ilkay, Teater, Matt, Durant, Matt, Du, Guangyan, Xia, Min, Bilchuk, Natalia, Chennamadhavuni, Spandan, Palladino, Giuseppe, Inghirami, Giorgio, Philippar, Ulrike, Wu, Hao, Scott, David A, Gray, Nathanael S, Melnick, Ari

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Development of CDK2 and CDK5 Dual Degrader TMX‐2172 von Teng, Mingxing, Jiang, Jie, He, Zhixiang, Kwiatkowski, Nicholas P., Donovan, Katherine A., Mills, Caitlin E., Victor, Chiara, Hatcher, John M., Fischer, Eric S., Sorger, Peter K., Zhang, Tinghu, Gray, Nathanael S.

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Copper(I)-Catalyzed Addition of Grignard Reagents to in Situ-Derived N-Sulfonyl Azoalkenes: An Umpolung Alkylation Procedure Applicable to the Formation of Up to Three Contiguous Q... von Hatcher, John M, Coltart, Don M

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Development of Highly Potent and Selective Steroidal Inhibitors and Degraders of CDK8 von Hatcher, John M, Wang, Eric S, Johannessen, Liv, Kwiatkowski, Nicholas, Sim, Taebo, Gray, Nathanael S

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Development of a highly potent and selective degrader of LRRK2 von Hatcher, John M., Zwirek, Monika, Sarhan, Adil R., Vatsan, Prasanna S., Tonelli, Francesca, Alessi, Dario R., Davies, Paul, Gray, Nathanael S.

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Louis Gregory von Hatcher, John

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Helen Elsie Austin von Hatcher, John

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Catalytic Degraders Effectively Address Kinase Site Mutations in EML4-ALK Oncogenic Fusions von Gao, Yang, Jiang, Baishan, Kim, Hellen, Berberich, Matthew J., Che, Jianwei, Donovan, Katherine A., Hatcher, John M., Huerta, Fidel, Kwiatkowski, Nicholas P., Liu, Yingpeng, Liuni, Peter P., Metivier, Rebecca J., Murali, Vineeth K., Nowak, Radosław P., Zhang, Tinghu, Fischer, Eric S., Gray, Nathanael S., Jones, Lyn H.

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A kinase-independent role for CDK8 in BCR-ABL1+ leukemia von Menzl, Ingeborg, Zhang, Tinghu, Berger-Becvar, Angelika, Grausenburger, Reinhard, Heller, Gerwin, Prchal-Murphy, Michaela, Edlinger, Leo, Knab, Vanessa M., Uras, Iris Z., Grundschober, Eva, Bauer, Karin, Roth, Mareike, Skucha, Anna, Liu, Yao, Hatcher, John M., Liang, Yanke, Kwiatkowski, Nicholas P., Fux, Daniela, Hoelbl-Kovacic, Andrea, Kubicek, Stefan, Melo, Junia V., Valent, Peter, Weichhart, Thomas, Grebien, Florian, Zuber, Johannes, Gray, Nathanael S., Sexl, Veronika

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Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors von Malone, Clare F, Kim, Minjee, Alexe, Gabriela, Engel, Kathleen, Forman, Alexandra B, Robichaud, Amanda, Conway, Amy Saur, Goodale, Amy, Meyer, Ashleigh, Khalid, Delan, Thayakumar, Allen, Hatcher, John M, Gray, Nathanael S, Piccioni, Federica, Stegmaier, Kimberly

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A Novel HER2-Selective Kinase Inhibitor Is Effective in HER2 Mutant and Amplified Non-Small Cell Lung Cancer von Son, Jieun, Jang, Jaebong, Beyett, Tyler S, Eum, Yoonji, Haikala, Heidi M, Verano, Alyssa, Lin, Mika, Hatcher, John M, Kwiatkowski, Nicholas P, Eser, Pinar Ö, Poitras, Michael J, Wang, Stephen, Xu, Man, Gokhale, Prafulla C, Cameron, Michael D, Eck, Michael J, Gray, Nathanael S, Jänne, Pasi A

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Characterization of DDR2 Inhibitors for the Treatment of DDR2 Mutated Nonsmall Cell Lung Cancer von Terai, Hideki, Tan, Li, Beauchamp, Ellen M, Hatcher, John M, Liu, Qingsong, Meyerson, Matthew, Gray, Nathanael S, Hammerman, Peter S

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Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor–associated kinase 4 (IRAK4) von Wang, Li, Ferrao, Ryan, Li, Qiubai, Hatcher, John M., Choi, Hwan Geun, Buhrlage, Sara J., Gray, Nathanael S., Wu, Hao

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Discovery of Inhibitors That Overcome the G1202R Anaplastic Lymphoma Kinase Resistance Mutation von Hatcher, John M, Bahcall, Magda, Choi, Hwan Geun, Gao, Yang, Sim, Taebo, George, Rani, Jänne, Pasi A, Gray, Nathanael S

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Peptide-based covalent inhibitors of MALT1 paracaspase von Hatcher, John M., Du, Guangyan, Fontán, Lorena, Us, Ilkay, Qiao, Qi, Chennamadhavuni, Spandan, Shao, Jay, Wu, Hao, Melnick, Ari, Gray, Nathanael S., Scott, David A.

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Quinoline and thiazolopyridine allosteric inhibitors of MALT1 von Scott, David A., Hatcher, John M., Liu, Hongyan, Fu, Mingpeng, Du, Guangyan, Fontán, Lorena, Us, Ilkay, Casalena, Gabriella, Qiao, Qi, Wu, Hao, Melnick, Ari, Gray, Nathanael S.

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