Proteomic analysis of gemcitabine-resistant pancreatic cancer cells reveals that microtubule-associated protein 2 upregulation associates with taxane treatment von Le Large, Tessa Ya Sung, El Hassouni, Btissame, Funel, Niccola, Kok, Bart, Piersma, Sander R., Pham, Thang V., Olive, Kenneth P., Kazemier, Geert, van Laarhoven, Hanneke W.M., Jimenez, Connie R., Bijlsma, Maarten F., Giovannetti, Elisa

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Multidrug‐resistant transporter expression does not always result in drug resistance von Le Large, Tessa Ya Sung, El Hassouni, Btissame, Kazemier, Geert, Piersma, Sander R., Laarhoven, Hanneke W. M., Bijlsma, Maarten F., Jimenez, Cornelia R., Giovannetti, Elisa

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MicroRNAs as a drug resistance mechanism to targeted therapies in EGFR-mutated NSCLC: Current implications and future directions von Leonetti, Alessandro, Assaraf, Yehuda G., Veltsista, Paraskevi D., El Hassouni, Btissame, Tiseo, Marcello, Giovannetti, Elisa

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Antibiotics and Adverse Events in Patients with Pancreatic Cancer Treated with Gemcitabine: Looking for Novel Clinical and Preclinical Insights von El Hassouni, Btissame, Gregori, Alessandro, Puik, Jisce R., Deng, Dongmei, Kazemier, Geert, Giovannetti, Elisa

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CX-5461 Inhibits Pancreatic Ductal Adenocarcinoma Cell Growth, Migration and Induces DNA Damage von El Hassouni, Btissame, Mantini, Giulia, Immordino, Benoît, Peters, Godefridus J, Giovannetti, Elisa

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3-(6-Phenylimidazo [2,1-b][1,3,4]thiadiazol-2-yl)-1H-Indole Derivatives as New Anticancer Agents in the Treatment of Pancreatic Ductal Adenocarcinoma von Cascioferro, Stella, Li Petri, Giovanna, Parrino, Barbara, El Hassouni, Btissame, Carbone, Daniela, Arizza, Vincenzo, Perricone, Ugo, Padova, Alessandro, Funel, Niccola, Peters, Godefridus J., Cirrincione, Girolamo, Giovannetti, Elisa, Diana, Patrizia

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Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds von Li Petri, Giovanna, El Hassouni, Btissame, Sciarrillo, Rocco, Funel, Niccola, Mantini, Giulia, Zeeuw van der Laan, Eveline A., Cascioferro, Stella, Avan, Amir, Zucali, Paolo Andrea, Zaffaroni, Nadia, Lagerweij, Tonny, Parrino, Barbara, Smid, Kees, Deraco, Marcello, Granchi, Carlotta, Braczko, Alicja, Smolenski, Ryszard T., Matherly, Larry H., Jansen, Gerrit, Assaraf, Yehuda G., Diana, Patrizia, Cloos, Jacqueline, Peters, Godefridus J., Minutolo, Filippo, Giovannetti, Elisa

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Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells von Firuzi, Omidreza, Che, Pei Pei, El Hassouni, Btissame, Buijs, Mark, Coppola, Stefano, Löhr, Matthias, Funel, Niccola, Heuchel, Rainer, Carnevale, Ilaria, Schmidt, Thomas, Mantini, Giulia, Avan, Amir, Saso, Luciano, Peters, Godefridus J, Giovannetti, Elisa

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Exploring Splicing Modulation as an Innovative Approach to Combat Pancreatic Cancer: SF3B1 Emerges as a Prognostic Indicator and Therapeutic Target von Sciarrillo, Rocco, Terrana, Francesca, Comandatore, Annalisa, Supadmanaba, I Gede Putu, Wang, Bing, Hassouni, Btissame El, Mantini, Giulia, Jansen, Gerrit, Avan, Amir, Carbone, Daniela, Diana, Patrizia, Peters, Godefridus J, Morelli, Luca, Cloos, Jacqueline, Assaraf, Yehuda G, Giovannetti, Elisa

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RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the... von Sarkisjan, Dzjemma, Julsing, Joris R, El Hassouni, Btissame, Honeywell, Richard J, Kathmann, Ietje, Matherly, Larry H, Lee, Young B, Kim, Deog J, Peters, Godefridus J

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Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma von Sciarrillo, Rocco, Wojtuszkiewicz, Anna, El Hassouni, Btissame, Funel, Niccola, Gandellini, Paolo, Lagerweij, Tonny, Buonamici, Silvia, Blijlevens, Maxime, Zeeuw van der Laan, Eveline A., Zaffaroni, Nadia, Deraco, Marcello, Kusamura, Shigeki, Würdinger, Tom, Peters, Godefridus J., Molthoff, Carla F.M., Jansen, Gerrit, Kaspers, Gertjan J.L., Cloos, Jacqueline, Giovannetti, Elisa

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Dynamic Evaluation of Circulating miRNA Profile in EGFR-Mutated NSCLC Patients Treated with EGFR-TKIs von Leonetti, Alessandro, Capula, Mjriam, Minari, Roberta, Mazzaschi, Giulia, Gregori, Alessandro, El Hassouni, Btissame, Papini, Filippo, Bordi, Paola, Verzè, Michela, Avan, Amir, Tiseo, Marcello, Giovannetti, Elisa

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Gemcitabine resistant pancreatic cancer cells are sensitive to paclitaxel treatment von Le Large, Tessa, El Hassouni, Btissame, Kazemier, Geert, van Laarhoven, Hanneke, Jimenez, Connie, Bijlsma, Maarten, Giovannetti, Elisa

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Lactate dehydrogenase A inhibition by small molecular entities: steps in the right direction von El Hassouni, Btissame, Franczak, Marika, Capula, Mjriam, Vonk, Christian M, Gomez, Valentina M, Smolenski, Ryszard T, Granchi, Carlotta, Peters, Godefridus J, Minutolo, Filippo, Giovannetti, Elisa

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The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: Interplay with the complex tumor microenvironment and novel therapeutic strategies von El Hassouni, Btissame, Granchi, Carlotta, Vallés-Martí, Andrea, Supadmanaba, I Gede Putu, Bononi, Giulia, Tuccinardi, Tiziano, Funel, Niccola, Jimenez, Connie R., Peters, Godefridus J., Giovannetti, Elisa, Minutolo, Filippo

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Abstract 3082: Targeting hypoxic pancreatic cancer cells with glucose conjugated lactate dehydrogenase inhibitor NHI-Glc-2 von Hassouni, Btissame El, Sciarrillo, Rocco, Gómez, Valentina Edith, Maftouh, Mina, Mantini, Giulia, Vonk, Christian M., Granchi, Carlotta, Funel, Niccola, Minutolo, Filippo, Peters, Godefridus J., Giovannetti, Elisa

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Abstract 5861: RX-3117 promotes epigenetic effects in cancer cells through enhanced degradation of DNMT1 von Sarkisjan, Dzjemma, Pronk, Ferry, Kuin, Rosan, Hassouni, Btissame el, Lee, Young B., Kim, Deog J., Dijk, Marc, Geerke, Daan P., Peters, G. J.

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Abstract 1267: Unusual mechanism of resistance to the novel cytidine analog fluorocyclopentenylcytosine (RX-3117) von Peters, Godefridus J., Sarkisjan, Dzjemma, Hassouni, Btissame El, Honeywell, Richard J., Julsing, Joris R., Balboni, Beatrice, Klerk, Daniel J. De, Zekanovic, Safet, Smid, Kees, Giovannetti, Elisa, Lee, Young B., Kim, Deog J.

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Abstract 4141: Phosphoproteome networks display consistent hyperactive kinase activity in pancreatic cancer: evidence for new therapeutic options von Large, Tessa Y. Le, Bijlsma, Maarten F., Hassouni, Btissame El, Funel, Nicolla, Grieken, Nicole C. van, Damhofer, Helene, Knol, Jaco C., Piersma, Sander R., Pham, Thang V., Verheul, Henk M., Laarhoven, Hanneke W. van, Kazemier, Geert, Giovannetti, Elisa, Jimenez, Connie R.

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Lactate dehydrogenase A inhibition by small molecular entities: steps in the right direction von Hassouni, Btissame El, Franczak, Marika, Capula, Mjriam, Vonk, Christian M., Gomez, Valentina M., Smolenski, Ryszard T., Granchi, Carlotta, Peters, Godefridus J., Minutolo, Filippo, Giovannetti, Elisa

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