S180: RG6234, A NOVEL GPRC5D T‐CELL ENGAGING BISPECIFIC ANTIBODY, INDUCES RAPID RESPONSES IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA: PRELIMINARY RESULTS FROM A FIRST‐IN... von Hasselbalch Riley, C., Hutchings, M., Yoon, S.‐S., Koh, Y., Manier, S., Facon, T., Harrison, S. J., Er, J., Volzone, F., Pinto, A., Montes, C., Ocio, E. M., Alfonso‐Pierola, A., Rodriguez Otero, P., Offner, F., Guidetti, A., Corradini, P., Titouan, C., Hulin, C., Touzeau, C., Moreau, P., Popat, R., Leong, S., Mazza, R., Bröske, A.‐M. E., Dekhtiarenko, I., Helms, H.‐J., Belli, S., Vardar, T., Fauti, T., Eckmann, J., Moore, T., Schneider, M., Jacob, W., Weisser, M., Carlo‐Stella, C.

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S173: T‐CELL ACTIVATION AND MYELOMA CELL KILLING CONFIRM THE MODE OF ACTION OF RG6234, A NOVEL GPRC5D T‐CELL ENGAGING BISPECIFIC ANTIBODY, IN PATIENTS WITH RELAPSED/REFRACTORY MULT... von Dekhtiarenko, I., Lelios, I., Attig, J., Sleiman, N., Lazzaro, D., Clausen, I., Gräfe, N., Helms, H.‐J., Schindler, E., Belli, S., Fauti, T., Eckmann, J., Umana, P., Jacob, W., Schneider, M., Hasselbalch Riley, C., Hutchings, M., Yoon, S.‐S., Koh, Y, Manier, S., Facon, T., Harrison, S. J., Er, J., Volzone, F., Pinto, A., Montes, C., Ocio, E. M., Alfonso‐Pierola, A., Rodríguez Otero, P., Offner, F., Guidetti, A., Corradini, P., Titouan, C., Hulin, C., Touzeau, C., Moreau, P., Popat, R., Leong, S., Mazza, R., Carlo‐Stella, C., Bröske, A.‐M. E.

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Correction: Whole blood transcriptional profiling reveals deregulation of oxidative and antioxidative defence genes in myelofibrosis and related neoplasms. Potential implications o...

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The calreticulin (CALR) exon 9 mutations are promising targets for cancer immune therapy von Holmström, M O, Martinenaite, E, Ahmad, S M, Met, Ö, Friese, C, Kjær, L, Riley, C H, thor Straten, P, Svane, I M, Hasselbalch, H C, Andersen, M H

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The CALR exon 9 mutations are shared neoantigens in patients with CALR mutant chronic myeloproliferative neoplasms von Holmström, M O, Riley, C H, Svane, I M, Hasselbalch, H C, Andersen, M H

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The JAK2V617F mutation is a target for specific T cells in the JAK2V617F-positive myeloproliferative neoplasms von Holmström, M O, Hjortsø, M D, Ahmad, S M, Met, Ö, Martinenaite, E, Riley, C, Straten, P, Svane, I M, Hasselbalch, H C, Andersen, M H

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Interferon-α induces marked alterations in circulating regulatory T cells, NK cell subsets, and dendritic cells in patients with JAK2V617F-positive essential thrombocythemia and po... von Riley, Caroline H., Brimnes, Marie K., Hansen, Morten, Jensen, Morten Krogh, Hasselbalch, Hans C., Kjaer, Lasse, Straten, Per thor, Svane, Inge Marie

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B‐cell frequencies and immunoregulatory phenotypes in myeloproliferative neoplasms: Influence of ruxolitinib, interferon‐α2, or combination treatment von Sørensen, Anders Lindholm, Bjørn, Mads Emil, Riley, Caroline H., Holmstrøm, Morten, Andersen, Mads Hald, Svane, Inge Marie, Mikkelsen, Stine Ulrik, Skov, Vibe, Kjær, Lasse, Hasselbalch, Hans C., Nielsen, Claus H.

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High frequencies of circulating memory T cells specific for calreticulin exon 9 mutations in healthy individuals von Holmström, Morten O., Ahmad, Shamaila M., Klausen, Uffe, Bendtsen, Simone K., Martinenaite, Evelina, Riley, Caroline H., Svane, Inge M., Kjær, Lasse, Skov, Vibe, Ellervik, Christina, Pallisgaard, Niels, Hasselbalch, Hans C., Andersen, Mads H.

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Siremadlin, a Human Double Minute-2 (HDM2) Inhibitor, Added to Ruxolitinib after Suboptimal Response to Ruxolitinib Alone in Patients with Myelofibrosis: Results from Part 1 of the... von Heidel, Florian H, Perkins, Andrew Charles, Reiter, Andreas, Crodel, Carl C., Riley, Caroline Hasselbalch, Gómez-Casares, María Teresa, Takacs, Istvan, Becker, Heiko, Lehmann, Thomas, Vinogradova, Olga, Burbury, Kate, Vannucchi, Alessandro M., Gupta, Vikas, Harrison, Claire, Wondergem, Marielle, Kiladjian, Jean-Jacques, Cleary, Grace, Zhang, Angela, Mahuzier, Bruyère, Kota, Jagannath, Prahallad, Anirudh, Ross, David M

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The calreticulin von Riley, C H, Kjaer, L, Holmström, M O, thor Straten, P, Friese, C, Ahmad, S M, Hasselbalch, H C, Martinenaite, E, Svane, I M, Andersen, M H, Met, Ö

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Expansion of circulating CD56bright natural killer cells in patients with JAK2-positive chronic myeloproliferative neoplasms during treatment with interferon-α von Riley, Caroline H., Hansen, Morten, Brimnes, Marie K., Hasselbalch, Hans C., Bjerrum, Ole W., Straten, Per thor, Svane, Inge Marie, Jensen, Morten Krogh

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Interferon‐α induces marked alterations in circulating regulatory T cells, NK cell subsets, and dendritic cells in patients with JAK 2V617F‐positive essential thrombocythemia and p... von Riley, Caroline H., Brimnes, Marie K., Hansen, Morten, Jensen, Morten Krogh, Hasselbalch, Hans C., Kjaer, Lasse, Straten, Per thor, Svane, Inge Marie

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Expansion of circulating CD56 bright natural killer cells in patients with JAK2‐positive chronic myeloproliferative neoplasms during treatment with interferon‐α von Riley, Caroline H., Hansen, Morten, Brimnes, Marie K., Hasselbalch, Hans C., Bjerrum, Ole W., Straten, Per thor, Svane, Inge Marie, Jensen, Morten Krogh

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