Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition von Hasemann, Charles A, Ohren, Jeffrey F, Chen, Huifen, Pavlovsky, Alexander, Whitehead, Christopher, Zhang, Erli, Kuffa, Peter, Yan, Chunhong, McConnell, Patrick, Spessard, Cindy, Banotai, Craig, Mueller, W Thomas, Delaney, Amy, Omer, Charles, Sebolt-Leopold, Judith, Dudley, David T, Leung, Iris K, Flamme, Cathlin, Warmus, Joseph, Kaufman, Michael, Barrett, Stephen, Tecle, Haile

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Structure and function of cytochromes P450:a comparative analysis of three crystal structures von Hasemann, Charles A, Kurumbail, Ravi G, Boddupalli, Sekhar S, Peterson, Julian A, Deisenhofer, Johann

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Innovation, entrepreneurship, promotion, and tenure von Carter, Rich G., Mundorff, Karl, Risien, Julie, Bouwma-Gearhart, Jana, Bratsch-Prince, Dawn, Brown, Sandra A., Campbell, Almesha L., Hartman, Joseph C., Hasemann, Charles A., Hollenbeck, Peter J., Lupiani, Blanca, McCarty, Owen J. T., McClure, Ian D., Mealey, Katrina, Mimura, Carol, Romero, Andrea J., Sztajn, Paola, Van Egeren, Laurie

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The Crystal Structure of Zn(II)-Free Treponema pallidum TroA, a Periplasmic Metal-Binding Protein, Reveals a Closed Conformation von Lee, Yong-Hwan, Dorwart, Michael R, Hazlett, Karsten R O, Deka, Ranjit K, Norgard, Michael V, Radolf, Justin D, Hasemann, Charles A

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Characterization of the Moraxella catarrhalis uspA1 and uspA2 Genes and Their Encoded Products von Cope, L D, Lafontaine, E R, Slaughter, C A, Hasemann, Jr, C A, Aebi, C, Henderson, F W, McCracken, Jr, G H, Hansen, E J

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Tissue-specific Structure/Function Differentiation of the Liver Isoform of 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase von Lee, Yong-Hwan, Li, Yang, Uyeda, Kosaku, Hasemann, Charles A.

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The crystal structure of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase reveals distinct domain homologies von Hasemann, Charles A, Istvan, Eva S, Uyeda, Kosaku, Deisenhofer, Johann

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Crystal Structure of Hemoprotein Domain of P450BM-3, a Prototype for Microsomal P450's von Ravichandran, Kurumbail G., Boddupalli, Sekhar S., Hasemann, Charles A., Peterson, Julian A., Deisenhofer, Johann

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Crystal structure and refinement of cytochrome P450terp at 2·3 Å resolution von Hasemann, Charles A., Ravichandran, K.G., Peterson, Julian A., Deisenhofer, Johann

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Physicochemical Evidence that Treponema pallidum TroA Is a Zinc-Containing Metalloprotein That Lacks Porin-Like Structure von Deka, R K, Lee, Y H, Hagman, K E, Shevchenko, D, Lingwood, C A, Hasemann, C A, Norgard, M V, Radolf, J D

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A Switch in the Kinase Domain of Rat Testis 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase von Yuen, Mi Ha, Wang, Xiao-li, Mizuguchi, Hiroyuki, Uyeda, Kosaku, Hasemann, Charles A

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Site-Directed Mutants of Rat Testis Fructose 6-Phosphate, 2-Kinase/Fructose 2,6-Bisphosphatase:  Localization of Conformational Alterations Induced by Ligand Binding von Helms, Michael K, Hazlett, Theodore L, Mizuguchi, Hiroyuki, Hasemann, Charles A, Uyeda, Kosaku, Jameson, David M

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Chemical Mechanism of the Fructose-6-Phosphate,2-Kinase Reaction from the pH Dependence of Kinetic Parameters of Site-Directed Mutants of Active Site Basic Residues von Mizuguchi, Hiroyuki, Cook, Paul F, Hasemann, Charles A, Uyeda, Kosaku

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Reaction Mechanism of Fructose-2,6-bisphosphatase von Mizuguchi, Hiroyuki, Cook, Paul F., Tai, Chia-Hui, Hasemann, Charles A., Uyeda, Kosaku

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Crystal Structure of the H256A Mutant of Rat Testis Fructose-6-phosphate,2-kinase/Fructose-2,6-bisphosphatase von Yuen, Mi H., Mizuguchi, Hiroyuki, Lee, Yong-Hwan, Cook, Paul F., Uyeda, Kosaku, Hasemann, Charles A.

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The Active Sites of Fructose 6-Phosphate,2-kinase: Fructose-2,6-bisphosphatase from Rat Testis von Uyeda, Kosaku, Wang, Xiao-Li, Mizuguchi, Hiroyuki, Li, Yang, Nguyen, Cu, Hasemann, Charles A.

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High-Level Production of a Functional Immunoglobulin Heterodimer in a Baculovirus Expression System von Hasemann, Charles A., Capra, J. Donald

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Treponema pallidum TroA is a periplasmic zinc-binding protein with a helical backbone von Hasemann, Charles A, Lee, Yong-Hwan, Deka, Ranjit K, Norgard, Michael V, Radolf, Justin D

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Reaction mechanism of fructose-2,6-bisphosphatase. A mutation of nucleophilic catalyst, histidine 256, induces an alteration in the reaction pathway von Mizuguchi, H, Cook, P F, Tai, C H, Hasemann, C A, Uyeda, K

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Crystal structure of the H256A mutant of rat testis fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. Fructose 6-phosphate in the active site leads to mechanisms for both... von Yuen, M H, Mizuguchi, H, Lee, Y H, Cook, P F, Uyeda, K, Hasemann, C A

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