Acetyl-coenzyme A carboxylases: Versatile targets for drug discovery von Tong, Liang, Harwood Jr, H. James

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Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models von Svensson, Robert U, Parker, Seth J, Eichner, Lillian J, Kolar, Matthew J, Wallace, Martina, Brun, Sonja N, Lombardo, Portia S, Van Nostrand, Jeanine L, Hutchins, Amanda, Vera, Lilliana, Gerken, Laurie, Greenwood, Jeremy, Bhat, Sathesh, Harriman, Geraldine, Westlin, William F, Harwood, H James, Saghatelian, Alan, Kapeller, Rosana, Metallo, Christian M, Shaw, Reuben J

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Treating the metabolic syndrome: acetyl-CoA carboxylase inhibition von Harwood Jr, H James

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Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2 von Corbett, Jeffrey W., Freeman-Cook, Kevin D., Elliott, Richard, Vajdos, Felix, Rajamohan, Francis, Kohls, Darcy, Marr, Eric, Zhang, Hailong, Tong, Liang, Tu, Meihua, Murdande, Sharad, Doran, Shawn D., Houser, Janet A., Song, Wei, Jones, Christopher J., Coffey, Steven B., Buzon, Leanne, Minich, Martha L., Dirico, Kenneth J., Tapley, Susan, Kirk McPherson, R., Sugarman, Eliot, James Harwood, H., Esler, William

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Old World nonhuman primate models of type 2 diabetes mellitus von Wagner, J.D, Kavanagh, K, Ward, G.M, Auerbach, B.J, Harwood, H.J. Jr, Kaplan, J.R

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Urology Residency Applicant Selection: Program Directors’ New Criteria von Rodriguez-Alvarez, Juan Sebastian, Munoz-Lopez, Carlos, Harwood, Samuel, Miranda, Andre F., Campbell, Steven C., DeWitt-Foy, Molly E., Khouri, Roger K.

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Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase von Harwood, H. James, Petras, Stephen F., Hoover, Dennis J., Mankowski, Dayna C., Soliman, Victor F., Sugarman, Eliot D., Hulin, Bernard, Kwon, Younggil, Gibbs, E. Michael, Mayne, James T., Treadway, Judith L.

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Cryo-EM structure of human ATP-citrate lyase in complex with a potent inhibitor von Wei, Jia, Leit, Silvana, Kuai, Jun, Therrien, Eric, Rafi, Salma, Harwood Jr, H. James, DeLaBarre, Byron, Tong, Liang

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Inhibition of Mammalian Squalene Synthetase Activity by Zaragozic Acid A Is a Result of Competitive Inhibition Followed by Mechanism-based Irreversible Inactivation von Lindsey, S, Harwood, Jr, H J

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HMG-CoA reductase regulation: use of structurally diverse first half-reaction squalene synthetase inhibitors to characterize the site of mevalonate-derived nonsterol regulator prod... von Petras, S F, Lindsey, S, Harwood, Jr, H J

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A selective cannabinoid-1 receptor antagonist, PF-95453, reduces body weight and body fat to a greater extent than pair-fed controls in obese monkeys von Wagner, Janice D, Zhang, Li, Kavanagh, Kylie, Ward, Gina M, Chin, Janice E, Hadcock, John R, Auerbach, Bruce J, Harwood, Jr, H James

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In Vivo LDL Receptor and HMG-CoA Reductase Regulation in Human Lymphocytes and Its Alterations During Aging von Stulnig, Thomas M, Klocker, Helmut, Harwood, Jr, Jurgens, Gunther, Schonitzer, Dieter, Jarosch, Elmar, Huber, Lukas A, Amberger, Albert, Wick, Georg

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Modulators of dyslipidaemia von Harwood, Jr, H James, Hamanaka, Ernest S

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Measurement of total hepatic low density lipoprotein receptor levels in the hamster von COSGROVE, P. G, GAYNOR, B. J, HARWOOD, H. J

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Effects of l-Triiodothyronine and the Thyromimetic L-94901 on Serum Lipoprotein Levels and Hepatic Low-Density Lipoprotein Receptor, 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase... von Ness, Gene C, Lopez, Dayami, Chambers, Christopher M, Newsome, William P, Cornelius, Peter, Long, Catherine A, Harwood, H.James

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Lanosterol 14alpha-demethylase (CYP51), NADPH-cytochrome P450 reductase and squalene synthase in spermatogenesis: late spermatids of the rat express proteins needed to synthesize f... von Majdic, G, Parvinen, M, Bellamine, A, Harwood HJ, Ku, WW, Waterman, MR, Rozman, D

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Partial blockage of sterol biosynthesis with a squalene synthase inhibitor in early postnatal Niemann-Pick type C npcnih null mice brains reduces neuronal cholesterol accumulation,... von Reid, Patrick C, Lin, Song, Vanier, Marie T, Ohno-Iwashita, Yoshiko, Harwood, Jr, H James, Hickey, William F, Chang, Catherine C Y, Chang, Ta Yuan

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Inhibition of human leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by ascorbic acid. An effect mediated by the free radical monodehydroascorbate von Harwood, H J, Greene, Y J, Stacpoole, P W

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Measurement of human leukocyte microsomal HMG-CoA reductase activity von Harwood, Jr, H J, Schneider, M, Stacpoole, P W

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HMG-CoA reductase kinase: measurement of activity by methods that preclude interference by inhibitors of HMG-CoA reductase activity or by mevalonate kinase von Harwood, Jr, H J, Rodwell, V W

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