A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo expansion of CD8 and NK cells von Harris, Katherine E., Lorentsen, Kyle J., Malik-Chaudhry, Harbani K., Loughlin, Kaitlyn, Basappa, Harish Medlari, Hartstein, Sharon, Ahmil, Ghenima, Allen, Nicole S., Avanzino, Brian C., Balasubramani, Aarti, Boudreau, Andrew A., Chang, Karen, Cuturi, Maria-Cristina, Davison, Laura M., Ho, Dennis M., Iyer, Suhasini, Rangaswamy, Udaya S., Sankaran, Preethi, Schellenberger, Ute, Buelow, Roland, Trinklein, Nathan D.

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A T-cell engaging bispecific antibody with a tumor-selective bivalent folate receptor alpha binding arm for the treatment of ovarian cancer von Avanzino, Brian C., Prabhakar, Kirthana, Dalvi, Pranjali, Hartstein, Sharon, Kehm, Hannes, Balasubramani, Aarti, Boudreau, Andrew A., Buelow, Ben, Chang, Karen, Davison, Laura M., Iyer, Suhasini, Kalwit, Vidyut, Lewis Wilson, Kristin, Malik-Chaudhry, Harbani K., Pierson, Will, Pineda, Geovanni, Rangaswamy, Udaya S., Saiganesh, Sowmya, Schellenberger, Ute, Ugamraj, Harshad S., Yabut, Rodolfovan D., Buelow, Roland, Chapman, Jocelyn, Trinklein, Nathan D., Harris, Katherine E.

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A CD3 x FRα T-cell engaging bispecific antibody for efficient killing of ovarian cancer cells with minimal cytokine release von Buelow, Ben, Avanzino, Brian, Balasubramani, Aarti, Boudreau, Andrew, Davison, Laura, Ganesan, Priya, Harris, Katherine, Hartstein, Sharon, Malik-Chaudhry, Harbani, Pham, Duy, Prabhakar, Kirthana, Rangaswamy, Udaya, Saiganesh, Sowmya, Schellenberger, Ute, Ugamraj, Harshad, Kehm, Hannes, Trinklein, Nathan, Iyer, Suhasini

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Abstract 6244: A T cell engaging bispecific antibody utilizing a bivalent tumor-selective folate receptor alpha binding arm for the treatment of ovarian cancer von Avanzino, Brian C., Prabhakar, Kirthana, Dalvi, Pranjali, Hartstein, Sharon, Kehm, Hannes, Balasubramani, Aarti, Boudreau, Andrew A., Buelow, Ben, Chang, Karen, Davison, Laura M., Iyer, Suhasini, Kalwit, Vidyut, Malik-Chaudhry, Harbani, Pierson, Will, Pineda, Geovanni, Rangaswamy, Udaya S., Saiganesh, Sowmya, Schellenberger, Ute, Ugamraj, Harshad S., Buelow, Roland, Chapman, Jocelyn, Trinklein, Nathan D., Harris, Katherine E.

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