Integration of phosphatidylinositol 3-kinase (PI3K) activity and inflammatory signaling pathways in autoimmune disease von Hartkamp, L.M

Volltext bestellen

SAT0066 NF-κB signaling in rheumatoid arthritis drives inflammation and joint destruction in part through inactivation of forkhead box class O transcription factors von Hartkamp, L.M., Grabiec, A.M., Ludikhuize, J., van Es, I.E., Tak, P.P., Reedquist, K.A.

Volltext

THU0536 The AGC Kinases Protein Kinase B (PKB) and Serum and Glucocorticoid Kinase (SGK) Differentially Regulate the Metabolic Activity and Inflammatory Activation of Rheumatoid Ar... von Hartkamp, L.M., van Es, I.E., Malvar Fernandez, B., Tak, P.P., Reedquist, K.A.

Volltext

AB0148 Histone deacetylase inhibitors prevent inflammation-mediated inactivation of the forkhead box class o transcription factor FOXO1 in rheumatoid arthritis von Grabiec, A.M., Hartkamp, L.M., van Baarsen, L.G.M., Korchynskyi, O., Tak, P.P., Reedquist, K.A.

Volltext

OP0304 BTK Inhibition Suppresses Inflammatory Cytokine Production and Affects Gene Expression in Human Macrophages and RA Synovial Tissue Explants von Hartkamp, L. M., van Es, I. E., Fine, J. S., Smith, M., Woods, J., Narula, S., DeMartino, J., Tak, P. P., Reedquist, K. A.

Volltext

OP0254 Cytokine-Induced JNK-Dependent Downregulation of the Forkhead Box O Transcription Factor Foxo1 Promotes Survival and Proliferation of Fibroblast-Like Synoviocytes in Rheumat... von Grabiec, A. M., Angiolilli, C., Hartkamp, L. M., van Baarsen, L. G., Tak, P. P., Baeten, D. L., Reedquist, K. A.

Volltext

THU0042 Colony-Stimulating Factor (CSF) Receptor 1 Blockade Overcomes Overlapping Effects of M-CSF and Interleukin-34 on Myeloid Differentiation and Gene Expression to Reduce Infla... von Garcia, S., Hartkamp, L. M., Tang, M. W., van Es, I., Lin, H., Long, L., Masteller, E. L., Wong, B. R., Tak, P. P., Reedquist, K. A.

Volltext