Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity von Docherty, Andrew J. P., Lyons, Alan, Smith, Bryan J., Wright, Edwina M., Stephens, Paul E., Harris, Tim J. R., Murphy, Gillian, Reynolds, John J.

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The Histone Demethylase KDM1A Sustains the Oncogenic Potential of MLL-AF9 Leukemia Stem Cells von Harris, William J., Huang, Xu, Lynch, James T., Spencer, Gary J., Hitchin, James R., Li, Yaoyong, Ciceri, Filippo, Blaser, Julian G., Greystoke, Brigit F., Jordan, Allan M., Miller, Crispin J., Ogilvie, Donald J., Somervaille, Tim C.P.

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New role of fat-free mass in cancer risk linked with genetic predisposition von Harris, Benjamin H. L., Di Giovannantonio, Matteo, Zhang, Ping, Harris, David A., Lord, Simon R., Allen, Naomi E., Maughan, Tim S., Bryant, Richard J., Harris, Adrian L., Bond, Gareth L., Buffa, Francesca M.

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Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces Differentiation in Acute Myeloid Leukemia von Maiques-Diaz, Alba, Spencer, Gary J., Lynch, James T., Ciceri, Filippo, Williams, Emma L., Amaral, Fabio M.R., Wiseman, Daniel H., Harris, William J., Li, Yaoyong, Sahoo, Sudhakar, Hitchin, James R., Mould, Daniel P., Fairweather, Emma E., Waszkowycz, Bohdan, Jordan, Allan M., Smith, Duncan L., Somervaille, Tim C.P.

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Dominant role of nucleotide substitution in the diversification of serotype 3 pneumococci over decades and during a single infection von Croucher, Nicholas J, Mitchell, Andrea M, Gould, Katherine A, Inverarity, Donald, Barquist, Lars, Feltwell, Theresa, Fookes, Maria C, Harris, Simon R, Dordel, Janina, Salter, Susannah J, Browall, Sarah, Zemlickova, Helena, Parkhill, Julian, Normark, Staffan, Henriques-Normark, Birgitta, Hinds, Jason, Mitchell, Tim J, Bentley, Stephen D

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IFITM3 restricts the morbidity and mortality associated with influenza von Everitt, Aaron R., Clare, Simon, Pertel, Thomas, John, Sinu P., Wash, Rachael S., Smith, Sarah E., Chin, Christopher R., Feeley, Eric M., Sims, Jennifer S., Adams, David J., Wise, Helen M., Kane, Leanne, Goulding, David, Digard, Paul, Anttila, Verneri, Baillie, J. Kenneth, Walsh, Tim S., Hume, David A., Palotie, Aarno, Xue, Yali, Colonna, Vincenza, Tyler-Smith, Chris, Dunning, Jake, Gordon, Stephen B., Smyth, Rosalind L., Openshaw, Peter J., Dougan, Gordon, Brass, Abraham L., Kellam, Paul

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Mapping the global prevalence, incidence, and mortality of Plasmodium falciparum, 2000–17: a spatial and temporal modelling study von Weiss, Daniel J, Lucas, Tim C D, Nguyen, Michele, Nandi, Anita K, Bisanzio, Donal, Battle, Katherine E, Cameron, Ewan, Twohig, Katherine A, Pfeffer, Daniel A, Rozier, Jennifer A, Gibson, Harry S, Rao, Puja C, Casey, Daniel, Bertozzi-Villa, Amelia, Collins, Emma L, Dalrymple, Ursula, Gray, Naomi, Harris, Joseph R, Howes, Rosalind E, Kang, Sun Yun, Keddie, Suzanne H, May, Daniel, Rumisha, Susan, Thorn, Michael P, Barber, Ryan, Fullman, Nancy, Huynh, Chantal K, Kulikoff, Xie, Kutz, Michael J, Lopez, Alan D, Mokdad, Ali H, Naghavi, Mohsen, Nguyen, Grant, Shackelford, Katya Anne, Vos, Theo, Wang, Haidong, Smith, David L, Lim, Stephen S, Murray, Christopher J L, Bhatt, Samir, Hay, Simon I, Gething, Peter W

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Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility von Mbarek, Hamdi, Steinberg, Stacy, Nyholt, Dale R., Gordon, Scott D., Miller, Michael B., McRae, Allan F., Hottenga, Jouke Jan, Day, Felix R., Willemsen, Gonneke, de Geus, Eco J., Davies, Gareth E., Martin, Hilary C., Penninx, Brenda W., Jansen, Rick, McAloney, Kerrie, Vink, Jacqueline M., Kaprio, Jaakko, Plomin, Robert, Spector, Tim D., Magnusson, Patrik K., Reversade, Bruno, Harris, R. Alan, Aagaard, Kjersti, Kristjansson, Ragnar P., Olafsson, Isleifur, Eyjolfsson, Gudmundur Ingi, Sigurdardottir, Olof, Iacono, William G., Lambalk, Cornelis B., Montgomery, Grant W., McGue, Matt, Ong, Ken K., Perry, John R.B., Martin, Nicholas G., Stefánsson, Hreinn, Stefánsson, Kari, Boomsma, Dorret I.

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Mapping the global endemicity and clinical burden of Plasmodium vivax, 2000–17: a spatial and temporal modelling study von Battle, Katherine E, Lucas, Tim C D, Nguyen, Michele, Howes, Rosalind E, Nandi, Anita K, Twohig, Katherine A, Pfeffer, Daniel A, Cameron, Ewan, Rao, Puja C, Casey, Daniel, Gibson, Harry S, Rozier, Jennifer A, Dalrymple, Ursula, Keddie, Suzanne H, Collins, Emma L, Harris, Joseph R, Guerra, Carlos A, Thorn, Michael P, Bisanzio, Donal, Fullman, Nancy, Huynh, Chantal K, Kulikoff, Xie, Kutz, Michael J, Lopez, Alan D, Mokdad, Ali H, Naghavi, Mohsen, Nguyen, Grant, Shackelford, Katya Anne, Vos, Theo, Wang, Haidong, Lim, Stephen S, Murray, Christopher J L, Price, Ric N, Baird, J Kevin, Smith, David L, Bhatt, Samir, Weiss, Daniel J, Hay, Simon I, Gething, Peter W

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The Concordance and Heritability of Type 2 Diabetes in 34,166 Twin Pairs From International Twin Registers: The Discordant Twin (DISCOTWIN) Consortium von Willemsen, Gonneke, Ward, Kirsten J., Bell, Christopher G., Christensen, Kaare, Bowden, Jocelyn, Dalgård, Christine, Harris, Jennifer R., Kaprio, Jaakko, Lyle, Robert, Magnusson, Patrik K.E., Mather, Karen A., Ordoňana, Juan R., Perez-Riquelme, Francisco, Pedersen, Nancy L., Pietiläinen, Kirsi H., Sachdev, Perminder S., Boomsma, Dorret I., Spector, Tim

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Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint von Schmidt, Nathalie M., Wing, Peter A. C., Diniz, Mariana O., Pallett, Laura J., Swadling, Leo, Harris, James M., Burton, Alice R., Jeffery-Smith, Anna, Zakeri, Nekisa, Amin, Oliver E., Kucykowicz, Stephanie, Heemskerk, Mirjam H., Davidson, Brian, Meyer, Tim, Grove, Joe, Stauss, Hans J., Pineda-Torra, Ines, Jolly, Clare, Jury, Elizabeth C., McKeating, Jane A., Maini, Mala K.

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Fluid administration for acute circulatory dysfunction using basic monitoring: narrative review and expert panel recommendations from an ESICM task force von Cecconi, Maurizio, Hernandez, Glenn, Dunser, Martin, Antonelli, Massimo, Baker, Tim, Bakker, Jan, Duranteau, Jacques, Einav, Sharon, Groeneveld, A. B. Johan, Harris, Tim, Jog, Sameer, Machado, Flavia R., Mer, Mervyn, Monge García, M. Ignacio, Myatra, Sheila Nainan, Perner, Anders, Teboul, Jean-Louis, Vincent, Jean-Louis, De Backer, Daniel

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Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer von Lord, Simon R., Cheng, Wei-Chen, Liu, Dan, Gaude, Edoardo, Haider, Syed, Metcalf, Tom, Patel, Neel, Teoh, Eugene J., Gleeson, Fergus, Bradley, Kevin, Wigfield, Simon, Zois, Christos, McGowan, Daniel R., Ah-See, Mei-Lin, Thompson, Alastair M., Sharma, Anand, Bidaut, Luc, Pollak, Michael, Roy, Pankaj G., Karpe, Fredrik, James, Tim, English, Ruth, Adams, Rosie F., Campo, Leticia, Ayers, Lisa, Snell, Cameron, Roxanis, Ioannis, Frezza, Christian, Fenwick, John D., Buffa, Francesca M., Harris, Adrian L.

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The Ontology of Biological Attributes (OBA)—computational traits for the life sciences von Stefancsik, Ray, Balhoff, James P., Balk, Meghan A., Ball, Robyn L., Bello, Susan M., Caron, Anita R., Chesler, Elissa J., de Souza, Vinicius, Gehrke, Sarah, Haendel, Melissa, Harris, Laura W., Harris, Nomi L., Ibrahim, Arwa, Koehler, Sebastian, Matentzoglu, Nicolas, McMurry, Julie A., Mungall, Christopher J., Munoz-Torres, Monica C., Putman, Tim, Robinson, Peter, Smedley, Damian, Sollis, Elliot, Thessen, Anne E., Vasilevsky, Nicole, Walton, David O., Osumi-Sutherland, David

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Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders von Nabais, Marta F, Laws, Simon M, Lin, Tian, Vallerga, Costanza L, Armstrong, Nicola J, Blair, Ian P, Kwok, John B, Mather, Karen A, Mellick, George D, Sachdev, Perminder S, Wallace, Leanne, Henders, Anjali K, Zwamborn, Ramona A J, Hop, Paul J, Lunnon, Katie, Pishva, Ehsan, Roubroeks, Janou A Y, Soininen, Hilkka, Tsolaki, Magda, Mecocci, Patrizia, Lovestone, Simon, Kłoszewska, Iwona, Vellas, Bruno, Furlong, Sarah, Garton, Fleur C, Henderson, Robert D, Mathers, Susan, McCombe, Pamela A, Needham, Merrilee, Ngo, Shyuan T, Nicholson, Garth, Pamphlett, Roger, Rowe, Dominic B, Steyn, Frederik J, Williams, Kelly L, Anderson, Tim J, Bentley, Steven R, Dalrymple-Alford, John, Fowder, Javed, Gratten, Jacob, Halliday, Glenda, Hickie, Ian B, Kennedy, Martin, Lewis, Simon J G, Montgomery, Grant W, Pearson, John, Pitcher, Toni L, Silburn, Peter, Zhang, Futao, Visscher, Peter M, Yang, Jian, Stevenson, Anna J, Hillary, Robert F, Marioni, Riccardo E, Harris, Sarah E, Deary, Ian J, Jones, Ashley R, Shatunov, Aleksey, Iacoangeli, Alfredo, van Rheenen, Wouter, van den Berg, Leonard H, Shaw, Pamela J, Shaw, Cristopher E, Morrison, Karen E, Al-Chalabi, Ammar, Veldink, Jan H, Hannon, Eilis, Mill, Jonathan, Wray, Naomi R, McRae, Allan F

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Early life exposure to phthalates in the Canadian Healthy Infant Longitudinal Development (CHILD) study: a multi-city birth cohort von Navaranjan, Garthika, Takaro, Tim K., Wheeler, Amanda J., Diamond, Miriam L., Shu, Huan, Azad, Meghan B., Becker, Allan B., Dai, Ruixue, Harris, Shelley A., Lefebvre, Diana L., Lu, Zihang, Mandhane, Piush J., McLean, Kathleen, Moraes, Theo J., Scott, James A., Turvey, Stuart E., Sears, Malcolm R., Subbarao, Padmaja, Brook, Jeffrey R.

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Integrative analysis of 111 reference human epigenomes von Kundaje, Anshul, Meuleman, Wouter, Ernst, Jason, Bilenky, Misha, Yen, Angela, Heravi-Moussavi, Alireza, Kheradpour, Pouya, Zhang, Zhizhuo, Wang, Jianrong, Ziller, Michael J., Amin, Viren, Whitaker, John W., Schultz, Matthew D., Ward, Lucas D., Sarkar, Abhishek, Quon, Gerald, Sandstrom, Richard S., Eaton, Matthew L., Wu, Yi-Chieh, Pfenning, Andreas R., Wang, Xinchen, Claussnitzer, Melina, Liu, Yaping, Coarfa, Cristian, Harris, R. Alan, Shoresh, Noam, Epstein, Charles B., Gjoneska, Elizabeta, Leung, Danny, Xie, Wei, Hawkins, R. David, Lister, Ryan, Hong, Chibo, Gascard, Philippe, Mungall, Andrew J., Moore, Richard, Chuah, Eric, Tam, Angela, Canfield, Theresa K., Hansen, R. Scott, Kaul, Rajinder, Sabo, Peter J., Bansal, Mukul S., Carles, Annaick, Dixon, Jesse R., Farh, Kai-How, Feizi, Soheil, Karlic, Rosa, Kim, Ah-Ram, Kulkarni, Ashwinikumar, Li, Daofeng, Lowdon, Rebecca, Elliott, GiNell, Mercer, Tim R., Neph, Shane J., Onuchic, Vitor, Polak, Paz, Rajagopal, Nisha, Ray, Pradipta, Sallari, Richard C., Siebenthall, Kyle T., Sinnott-Armstrong, Nicholas A., Stevens, Michael, Thurman, Robert E., Wu, Jie, Zhang, Bo, Zhou, Xin, Beaudet, Arthur E., Boyer, Laurie A., De Jager, Philip L., Farnham, Peggy J., Fisher, Susan J., Haussler, David, Jones, Steven J. M., Li, Wei, Marra, Marco A., McManus, Michael T., Sunyaev, Shamil, Thomson, James A., Tlsty, Thea D., Tsai, Li-Huei, Wang, Wei, Waterland, Robert A., Zhang, Michael Q., Chadwick, Lisa H., Bernstein, Bradley E., Costello, Joseph F., Ecker, Joseph R., Hirst, Martin, Meissner, Alexander, Milosavljevic, Aleksandar, Ren, Bing, Stamatoyannopoulos, John A., Wang, Ting, Kellis, Manolis

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Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing von Zhang, Qian, Vallerga, Costanza L, Walker, Rosie M, Lin, Tian, Henders, Anjali K, Montgomery, Grant W, He, Ji, Fan, Dongsheng, Fowdar, Javed, Kennedy, Martin, Pitcher, Toni, Pearson, John, Halliday, Glenda, Kwok, John B, Hickie, Ian, Lewis, Simon, Anderson, Tim, Silburn, Peter A, Mellick, George D, Harris, Sarah E, Redmond, Paul, Murray, Alison D, Porteous, David J, Haley, Christopher S, Evans, Kathryn L, McIntosh, Andrew M, Yang, Jian, Gratten, Jacob, Marioni, Riccardo E, Wray, Naomi R, Deary, Ian J, McRae, Allan F, Visscher, Peter M

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Lichens: A limit to peat growth? von Harris, Lorna I., Moore, Tim R., Roulet, Nigel T., Pinsonneault, Andrew J.

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Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution von Venkatesan, Subramanian, Angelova, Mihaela, Puttick, Clare, Zhai, Haoran, Caswell, Deborah R, Lu, Wei-Ting, Dietzen, Michelle, Galanos, Panagiotis, Evangelou, Konstantinos, Bellelli, Roberto, Lim, Emilia L, Watkins, Thomas B K, Rowan, Andrew, Teixeira, Vitor H, Zhao, Yue, Chen, Haiquan, Ngo, Bryan, Zalmas, Lykourgos-Panagiotis, Al Bakir, Maise, Hobor, Sebastijan, Grönroos, Eva, Pennycuick, Adam, Nigro, Ersilia, Campbell, Brittany B, Brown, William L, Akarca, Ayse U, Marafioti, Teresa, Wu, Mary Y, Howell, Michael, Boulton, Simon J, Bertoli, Cosetta, Fenton, Tim R, de Bruin, Robertus A M, Maya-Mendoza, Apolinar, Santoni-Rugiu, Eric, Hynds, Robert E, Gorgoulis, Vassilis G, Jamal-Hanjani, Mariam, McGranahan, Nicholas, Harris, Reuben S, Janes, Sam M, Bartkova, Jirina, Bakhoum, Samuel F, Bartek, Jiri, Kanu, Nnennaya, Swanton, Charles

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