Molecular Dynamics Simulations Guide Chimeragenesis and Engineered Control of Chemoselectivity in Diketopiperazine Dimerases von Shende, Vikram V., Harris, Natalia R., Sanders, Jacob N., Newmister, Sean A., Khatri, Yogan, Movassaghi, Mohammad, Houk, Kendall N., Sherman, David H.

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Molecular Dynamics Simulations Guide Chimeragenesis and Engineered Control of Chemoselectivity in Diketopiperazine Dimerases von Shende, Vikram V., Harris, Natalia R., Sanders, Jacob N., Newmister, Sean A., Khatri, Yogan, Movassaghi, Mohammad, Houk, Kendall N., Sherman, David H.

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Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals von Lee, James J., Wedow, Robbee, Okbay, Aysu, Kong, Edward, Maghzian, Omeed, Zacher, Meghan, Nguyen-Viet, Tuan Anh, Bowers, Peter, Sidorenko, Julia, Karlsson Linnér, Richard, Fontana, Mark Alan, Kundu, Tushar, Lee, Chanwook, Li, Hui, Li, Ruoxi, Royer, Rebecca, Timshel, Pascal N., Walters, Raymond K., Willoughby, Emily A., Yengo, Loïc, Alver, Maris, Bao, Yanchun, Clark, David W., Day, Felix R., Furlotte, Nicholas A., Joshi, Peter K., Kemper, Kathryn E., Kleinman, Aaron, Langenberg, Claudia, Mägi, Reedik, Trampush, Joey W., Verma, Shefali Setia, Wu, Yang, Lam, Max, Zhao, Jing Hua, Zheng, Zhili, Boardman, Jason D., Campbell, Harry, Freese, Jeremy, Harris, Kathleen Mullan, Hayward, Caroline, Herd, Pamela, Kumari, Meena, Lencz, Todd, Luan, Jian’an, Malhotra, Anil K., Metspalu, Andres, Milani, Lili, Ong, Ken K., Perry, John R. B., Porteous, David J., Ritchie, Marylyn D., Smart, Melissa C., Smith, Blair H., Tung, Joyce Y., Wareham, Nicholas J., Wilson, James F., Beauchamp, Jonathan P., Conley, Dalton C., Esko, Tõnu, Lehrer, Steven F., Magnusson, Patrik K. E., Oskarsson, Sven, Pers, Tune H., Robinson, Matthew R., Thom, Kevin, Watson, Chelsea, Chabris, Christopher F., Meyer, Michelle N., Laibson, David I., Yang, Jian, Johannesson, Magnus, Koellinger, Philipp D., Turley, Patrick, Visscher, Peter M., Benjamin, Daniel J., Cesarini, David

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Genome of an arbuscular mycorrhizal fungus provides insight into the oldest plant symbiosis von Tisserant, Emilie, Malbreil, Mathilde, Kuo, Alan, Kohler, Annegret, Symeonidi, Aikaterini, Balestrini, Raffaella, Charron, Philippe, Duensing, Nina, Frey, Nicolas Frei dit, Gianinazzi-Pearson, Vivienne, Gilbert, Luz B., Handa, Yoshihiro, Herr, Joshua R., Hijri, Mohamed, Koul, Raman, Kawaguchi, Masayoshi, Krajinski, Franziska, Lammers, Peter J., Masclaux, Frederic G., Murat, Claude, Morin, Emmanuelle, Ndikumana, Steve, Pagni, Marco, Petitpierre, Denis, Requena, Natalia, Rosikiewicz, Pawel, Riley, Rohan, Saito, Katsuharu, Clemente, Hélène San, Shapiro, Harris, van Tuinen, Diederik, Bécard, Guillaume, Bonfante, Paola, Paszkowski, Uta, Shachar-Hill, Yair Y., Tuskan, Gerald A., Young, Peter W., Sanders, Ian R., Henrissat, Bernard, Rensing, Stefan A., Grigoriev, Igor V., Corradi, Nicolas, Roux, Christophe, Martin, Francis

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Interaction between the microbiome and TP53 in human lung cancer von Greathouse, K Leigh, White, James R, Vargas, Ashely J, Bliskovsky, Valery V, Beck, Jessica A, von Muhlinen, Natalia, Polley, Eric C, Bowman, Elise D, Khan, Mohammed A, Robles, Ana I, Cooks, Tomer, Ryan, Bríd M, Padgett, Noah, Dzutsev, Amiran H, Trinchieri, Giorgio, Pineda, Marbin A, Bilke, Sven, Meltzer, Paul S, Hokenstad, Alexis N, Stickrod, Tricia M, Walther-Antonio, Marina R, Earl, Joshua P, Mell, Joshua C, Krol, Jaroslaw E, Balashov, Sergey V, Bhat, Archana S, Ehrlich, Garth D, Valm, Alex, Deming, Clayton, Conlan, Sean, Oh, Julia, Segre, Julie A, Harris, Curtis C

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Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence von Joruiz, Sebastien M., Von Muhlinen, Natalia, Horikawa, Izumi, Gilbert, Mark R., Harris, Curtis C.

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Both N-Terminal and C-Terminal Histidine Residues of the Prion Protein Are Essential for Copper Coordination and Neuroprotective Self-Regulation von Schilling, Kevin M., Tao, Lizhi, Wu, Bei, Kiblen, Joseph T.M., Ubilla-Rodriguez, Natalia C., Pushie, M. Jake, Britt, R. David, Roseman, Graham P., Harris, David A., Millhauser, Glenn L.

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Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes von Chauhan, Ganesh, Traylor, Matthew, Sargurupremraj, Muralidharan, Okada, Yukinori, Mishra, Aniket, Giese, Anne-Katrin, van der Laan, Sander W., Gretarsdottir, Solveig, Anderson, Christopher D., Almgren, Peter, Amouyel, Philippe, Bartz, Traci M., Benavente, Oscar R., Boncoraglio, Giorgio B., Butterworth, Adam S., Carrera, Caty, Chasman, Daniel I., Cotlarciuc, Ioana, Cruchaga, Carlos, de Bakker, Paul I. W., Duan, Qing, Gottesman, Rebecca F., Harris, Tamara B., Hassan, Ahamad, Havulinna, Aki S., Heckbert, Susan R., Hyacinth, Hyacinth I., Ikram, M. Arfan, Ingelsson, Erik, Jian, Xueqiu, Jukema, J. Wouter, Kanai, Masahiro, Keene, Keith L., Kissela, Brett M., Kleindorfer, Dawn O., Kooperberg, Charles, Lange, Leslie A., Langenberg, Claudia, Launer, Lenore J., Lemmens, Robin, Lewis, Cathryn M., Lin, Wei-Yu, Lorentzen, Erik, Magnusson, Patrik K., Meschia, James F., Mitchell, Braxton D., Mosley, Thomas H., Nalls, Michael A., O’Donnell, Martin J., Pulit, Sara L., Reiner, Alexander P., Ridker, Paul M., Rothwell, Peter M., Rotter, Jerome I., Sale, Michele M., Salomaa, Veikko, Sapkota, Bishwa R., Schmidt, Reinhold, Schmidt, Carsten O., Sharma, Pankaj, Slowik, Agnieszka, Sudlow, Cathie L. M., Tanislav, Christian, Thijs, Vincent N. S., Thorsteinsdottir, Unnur, Tiedt, Steffen, Trompet, Stella, Wareham, Nicholas J., Wassertheil-Smoller, Sylvia, Wilson, James G., Pastinen, Tomi, Ruusalepp, Arno, Koplev, Simon, Björkegren, Johan L. M., Codoni, Veronica, Civelek, Mete, Christophersen, Ingrid E., Roselli, Carolina, Ellinor, Patrick T., Kato, Norihiro, van der Harst, Pim, Elliott, Paul, Takeuchi, Fumihiko, Johnson, Andrew D., Sanghera, Dharambir K., Melander, Olle, Strbian, Daniel, Fernandez-Cadenas, Israel, Rolfs, Arndt, Hata, Jun, Woo, Daniel, Pare, Guillaume, Hopewell, Jemma C., Saleheen, Danish, Stefansson, Kari, Worrall, Bradford B., Seshadri, Sudha, Markus, Hugh S., Debette, Stephanie, Dichgans, Martin

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Organization of left–right coordination of neuronal activity in the mammalian spinal cord: Insights from computational modelling von Shevtsova, Natalia A., Talpalar, Adolfo E., Markin, Sergey N., Harris‐Warrick, Ronald M., Kiehn, Ole, Rybak, Ilya A.

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N-glycosylation is a potent regulator of prion protein neurotoxicity von Schilling, Kevin M., Jorwal, Pooja, Ubilla-Rodriguez, Natalia C., Assafa, Tufa E., Gatdula, Jean R.P., Vultaggio, Janelle S., Harris, David A., Millhauser, Glenn L.

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Evaluating remission of type 2 diabetes using a metabolic intervention including fixed‐ratio insulin degludec and liraglutide: A randomized controlled trial von Punthakee, Zubin, Hall, Stephanie, McInnes, Natalia, Sherifali, Diana, Tsiplova, Kate, Kirabo, Faith R., Ransom, Thomas P. P., Harris, Stewart B., Lochnan, Heather A., Sigal, Ronald J., Ghosh, Mahua, Spaic, Tamara, Gerstein, Hertzel C.

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Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2 von Collier, Dami A., Ferreira, Isabella A. T. M., Kotagiri, Prasanti, Datir, Rawlings P., Lim, Eleanor Y., Touizer, Emma, Meng, Bo, Abdullahi, Adam, Elmer, Anne, Kingston, Nathalie, Graves, Barbara, Le Gresley, Emma, Caputo, Daniela, Bergamaschi, Laura, Smith, Kenneth G. C., Bradley, John R., Ceron-Gutierrez, Lourdes, Cortes-Acevedo, Paulina, Barcenas-Morales, Gabriela, Linterman, Michelle A., McCoy, Laura E., Davis, Chris, Thomson, Emma, Lyons, Paul A., McKinney, Eoin, Doffinger, Rainer, Wills, Mark, Gupta, Ravindra K.

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Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies von Collier, Dami A., De Marco, Anna, Ferreira, Isabella A. T. M., Meng, Bo, Datir, Rawlings P., Walls, Alexandra C., Kemp, Steven A., Bassi, Jessica, Pinto, Dora, Silacci-Fregni, Chiara, Bianchi, Siro, Tortorici, M. Alejandra, Bowen, John, Culap, Katja, Jaconi, Stefano, Cameroni, Elisabetta, Snell, Gyorgy, Pizzuto, Matteo S., Pellanda, Alessandra Franzetti, Garzoni, Christian, Riva, Agostino, Elmer, Anne, Kingston, Nathalie, Graves, Barbara, McCoy, Laura E., Smith, Kenneth G. C., Bradley, John R., Temperton, Nigel, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Harvey, William, Virgin, Herbert W., Lanzavecchia, Antonio, Piccoli, Luca, Doffinger, Rainer, Wills, Mark, Veesler, David, Corti, Davide, Gupta, Ravindra K.

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Effect of 2 Years of Treatment With Sublingual Grass Pollen Immunotherapy on Nasal Response to Allergen Challenge at 3 Years Among Patients With Moderate to Severe Seasonal Allergi... von Scadding, Guy W, Calderon, Moises A, Shamji, Mohamed H, Eifan, Aarif O, Penagos, Martin, Dumitru, Florentina, Sever, Michelle L, Bahnson, Henry T, Lawson, Kaitie, Harris, Kristina M, Plough, Audrey G, Panza, Joy Laurienzo, Qin, Tielin, Lim, Noha, Tchao, Nadia K, Togias, Alkis, Durham, Stephen R

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Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer von Riggan, Marjorie J, Beesley, Jonathan, Soucy, Penny, Aalfs, Cora M, Adams, Marcia, Arnold, Norbert, Arun, Banu K, Bean, Yukie, Bermisheva, Marina, Birrer, Michael J, Blankstein, Kenneth, Bonanni, Bernardo, Bradbury, Angela R, Broberg, Per, Campbell, Ian, Cannioto, Rikki, Cescon, Terence, Chan, Salina B, Chanock, Stephen, Claes, Kathleen B M, Conner, Thomas, Dansonka-Mieszkowska, Agnieszka, Davidson, Rosemarie, Dürst, Matthias, Ellis, Steve, Fasching, Peter A, Ferguson, Sarah, Frost, Debra, Gentry-Maharaj, Aleksandra, Gore, Martin, Gronwald, Jacek, Gruber, Stephen, Håkansson, Niclas, Hauke, Jan, Hildebrandt, Michelle A T, Høgdall, Claus K, Hogervorst, Frans B L, Hulick, Peter J, Imyanitov, Evgeny N, Izatt, Louise, Izquierdo, Angel, Jensen, Allan, Karnezis, Anthony, Kupryjanczyk, Jolanta, Lambrechts, Diether, Lee, Jong Won, Lele, Shashikant B, Leroux, Dominique, Lesueur, Fabienne, Lilyquist, Jenna, Mai, Phuong L, McAlpine, Jessica N, McGuire, Valerie, Mensenkamp, Arjen R, Modugno, Francesmary, Moes-Sosnowska, Joanna, Mulligan, Anna Marie, Musinsky, Jacob, Nedergaard, Lotte, Ness, Roberta B, Nevanlinna, Heli, Niederacher, Dieter, Nussbaum, Robert L, Onland-Moret, N Charlotte, Paul, James, Pelttari, Liisa M, Pezzani, Lidia, Phillips, Kelly-Anne, Poppe, Bruce, Prieur, Fabienne, Prokofyeva, Darya, Rice, Patricia, Rodriguez, Gustavo C, Rookus, Matti A, Senter, Leigha, Shelford, Tameka, Siddiqui, Nadeem, Side, Lucy E, Stadler, Zsofia, Sutphen, Rebecca, Sutter, Christian, Szabo, Csilla I, Terry, Kathryn L, Tihomirova, Laima, Tung, Nadine, Van Heetvelde, Mattias, Varon-Mateeva, Raymonda, Walsh, Christine, Wappenschmidt, Barbara, Webb, Penelope M, Weinberg, Clarice R, Weitzel, Jeffrey N, Yang, Hannah, Goodman, Marc T, Park, Sue K, Risch, Harvey A, Offit, Kenneth, Simard, Jacques, Chenevix-Trench, Georgia, Goode, Ellen L

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Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection von Adlam, David, Al-Hussaini, Abtehale, Bouajila, Sara, d’Escamard, Valentina, Huang, Siying, Margaritis, Marios, Nelson, Christopher P., Welch, Catherine A., Jeunemaitre, Xavier, Barnay, Pierre, Rioufol, Gilles, Range, Grégoire, Harbaoui, Brahim, Cayla, Guillaume, Champin, Stanislas, Saint-Etienne, Christophe, Marliere, Stéphanie, Karrillon, Gaëtan, Gerbay, Antoine, Houpe, David, Wong, Claire Mei Yi, Giannoulatou, Eleni, Sweeting, Michael, McGrath-Cadell, Lucy, Dunwoodie, Sally L., Harvey, Richard, Holloway, Cameron, Nikpay, Majid, Goel, Anuj, Won, Hong-Hee, Willenborg, Christina, Kanoni, Stavroula, Kyriakou, Theodosios, Nelson, Christopher P., Webb, Thomas R., Alver, Maris, Auro, Kirsi, Bjonnes, Andrew, Chasman, Daniel I., Franceschini, Nora, Gieger, Christian, Hwang, Shih-Jen, Kleber, Marcus E., Morrison, Alanna, Rose, Lynda M., Scholz, Markus, Smith, Albert V., Uitterlinden, Andre, Beutner, Frank, Gauguier, Dominique, Goodall, Alison H., Gottesman, Omri, Han, Bok-Ghee, Kessler, Thorsten, König, Inke R., Lannfelt, Lars, Lind, Lars, Lindgren, Cecilia M., Mallick, Nadeem H., Meitinger, Thomas, Morris, Andrew P., Nieminen, Markku S., Pedersen, Nancy L., Rasheed, Asif, Sinisalo, Juha, Trompet, Stella, Wang, Laiyuan, Boerwinkle, Eric, Demuth, Ilja, Epstein, Stephen E., Esko, Tõnu, Franco, Oscar H., Franzosi, Maria Grazia, Granger, Christopher B., Harris, Tamara B., Hofman, Albert, Ingelsson, Erik, Iribarren, Carlos, Jukema, J Wouter, Karhunen, Pekka J., Kim, Bong-Jo, Kooner, Jaspal S., Kullo, Iftikhar J., Palmer, Colin N., Perola, Markus, Ridker, Paul M., Ripatti, Samuli, Salomaa, Veikko, Seedorf, Udo, Stewart, Alexandre F., Stott, David J., Thiery, Joachim, Zalloua, Pierre A., Reilly, Muredach P., Clarke, Robert, Watkins, Hugh, Samani, Nilesh J., Farrall, Martin, Hayes, Sharonne N., Samani, Nilesh J.

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Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes: An Individual-Participant Data Meta-Analysis von Grams, Morgan E, Coresh, Josef, Matsushita, Kunihiro, Ballew, Shoshana H, Sang, Yingying, Surapaneni, Aditya, Alencar de Pinho, Natalia, Anderson, Amanda, Appel, Lawrence J, Ärnlöv, Johan, Azizi, Fereidoun, Bansal, Nisha, Bell, Samira, Bilo, Henk J G, Brunskill, Nigel J, Carrero, Juan J, Chadban, Steve, Chalmers, John, Chen, Jing, Ciemins, Elizabeth, Cirillo, Massimo, Ebert, Natalie, Evans, Marie, Ferreiro, Alejandro, Fu, Edouard L, Fukagawa, Masafumi, Green, Jamie A, Gutierrez, Orlando M, Herrington, William G, Hwang, Shih-Jen, Inker, Lesley A, Iseki, Kunitoshi, Jafar, Tazeen, Jassal, Simerjot K, Jha, Vivekanand, Kadota, Aya, Katz, Ronit, Köttgen, Anna, Konta, Tsuneo, Kronenberg, Florian, Lee, Brian J, Lees, Jennifer, Levin, Adeera, Looker, Helen C, Major, Rupert, Melzer Cohen, Cheli, Mieno, Makiko, Miyazaki, Mariko, Moranne, Olivier, Muraki, Isao, Naimark, David, Nitsch, Dorothea, Oh, Wonsuk, Pena, Michelle, Purnell, Tanjala S, Sabanayagam, Charumathi, Satoh, Michihiro, Sawhney, Simon, Schaeffner, Elke, Schöttker, Ben, Shen, Jenny I, Shlipak, Michael G, Sinha, Smeeta, Stengel, Benedicte, Sumida, Keiichi, Tonelli, Marcello, Valdivielso, Jose M, van Zuilen, Arjan D, Visseren, Frank L J, Wang, Angela Yee-Moon, Wen, Chi-Pang, Wheeler, David C, Yatsuya, Hiroshi, Yamagata, Kunihiro, Yang, Jae Won, Young, Ann, Zhang, Haitao, Zhang, Luxia, Levey, Andrew S, Gansevoort, Ron T

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Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis von Gurule, Natalia J., Malcolm, Kenneth C., Harris, Chelsea, Knapp, Jennifer R., O’Connor, Brian P., McClendon, Jazalle, Janssen, William J., Lee, Frank Fang Yao, Price, Caitlin, Osaghae-Nosa, Jackson, Wheeler, Emily A., McMahon, Christine M., Pietras, Eric M., Pollyea, Daniel A., Alper, Scott

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Separated Twins or Just Siblings? A Multiplanet System around an M Dwarf Including a Cool Sub-Neptune von Harris, Mallory, Dragomir, Diana, Mireles, Ismael, Collins, Karen A., Ulmer-Moll, Solène, Howell, Steve B., Stassun, Keivan G., Zhou, George, Ziegler, Carl, Bouchy, François, Briceño, César, Charbonneau, David, Collins, Kevin I., Fűűrész, Gábor, Guerrero, Natalia M., Jenkins, Jon M., Jensen, Eric L. N., Kristiansen, Martti H. K., Law, Nicholas, Lendl, Monika, Mann, Andrew W., Osborn, Hugh P., Quinn, Samuel N., Ricker, George R., Schwarz, Richard P., Seager, Sara, Ting, Eric B., Vanderspek, Roland, Watanabe, David, Winn, Joshua N.

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Managennent of latent Mycobacterium tuberculosis infection: WHO guidelines for Low tuberculosis burden countries von Getahun, H, Matteelli, A, Abubakar, I, Aziz, MA, Baddeley, A, Barreira, D, Den, Boon S, Borroto, Gutierrez SM, Bruchfeld, J, Burhan, E

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