Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome von Middleton, Elizabeth A., He, Xue-Yan, Denorme, Frederik, Campbell, Robert A., Ng, David, Salvatore, Steven P., Mostyka, Maria, Baxter-Stoltzfus, Amelia, Borczuk, Alain C., Loda, Massimo, Cody, Mark J., Manne, Bhanu Kanth, Portier, Irina, Harris, Estelle S., Petrey, Aaron C., Beswick, Ellen J., Caulin, Aleah F., Iovino, Anthony, Abegglen, Lisa M., Weyrich, Andrew S., Rondina, Matthew T., Egeblad, Mikala, Schiffman, Joshua D., Yost, Christian Con

Volltext

Sepsis alters the transcriptional and translational landscape of human and murine platelets von Middleton, Elizabeth A., Rowley, Jesse W., Campbell, Robert A., Grissom, Colin K., Brown, Samuel M., Beesley, Sarah J., Schwertz, Hansjörg, Kosaka, Yasuhiro, Manne, Bhanu K., Krauel, Krystin, Tolley, Neal D., Eustes, Alicia S., Guo, Li, Paine, Robert, Harris, Estelle S., Zimmerman, Guy A., Weyrich, Andrew S., Rondina, Matthew T.

Volltext

Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation von Yost, Christian C, Schwertz, Hansjörg, Cody, Mark J, Wallace, Jared A, Campbell, Robert A, Vieira-de-Abreu, Adriana, Araujo, Claudia V, Schubert, Sebastian, Harris, Estelle S, Rowley, Jesse W, Rondina, Matthew T, Fulcher, James M, Koening, Curry L, Weyrich, Andrew S, Zimmerman, Guy A

Volltext

Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates von Yost, Christian C., Cody, Mark J., Harris, Estelle S., Thornton, Nathan L., McInturff, Alison M., Martinez, Mark L., Chandler, Nancy B., Rodesch, Christopher K., Albertine, Kurt H., Petti, Cathy A., Weyrich, Andrew S., Zimmerman, Guy A.

Volltext

In Vivo Platelet Activation in Critically Ill Patients With Primary 2009 Influenza A(H1N1) von Rondina, Matthew T., MD, Brewster, BreAnna, Grissom, Colin K., MD, FCCP, Zimmerman, Guy A., MD, Kastendieck, Diana H., BA, Harris, Estelle S., MD, FCCP, Weyrich, Andrew S., PhD

Volltext

Integrin αDβ2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling von Miyazaki, Yasunari, Vieira-de-Abreu, Adriana, Harris, Estelle S, Shah, Amrapali M, Weyrich, Andrew S, Castro-Faria-Neto, Hugo C, Zimmerman, Guy A

Volltext

Passive Immunity Trial for Our Nation (PassITON): study protocol for a randomized placebo-control clinical trial evaluating COVID-19 convalescent plasma in hospitalized adults von Self, Wesley H., Stewart, Thomas G., Wheeler, Allison P., El Atrouni, Wissam, Bistran-Hall, Amanda J., Casey, Jonathan D., Cataldo, Vince D., Chappell, James D., Cohn, Claudia S., Collins, Jessica B., Denison, Mark R., de Wit, Marjolein, Dixon, Sheri L., Duggal, Abhijit, Edwards, Terri L., Fontaine, Magali J., Ginde, Adit A., Harkins, Michelle S., Harrington, Thelma, Harris, Estelle S., Hoda, Daanish, Ipe, Tina S., Jaiswal, Stuti J., Johnson, Nicholas J., Jones, Alan E., Laguio-Vila, Maryrose, Lindsell, Christopher J., Mallada, Jason, Mammen, Manoj J., Metcalf, Ryan A., Middleton, Elizabeth A., Mucha, Simon, O'Neal, Hollis R., Pannu, Sonal R., Pulley, Jill M., Qiao, Xian, Raval, Jay S., Rhoads, Jillian P., Schrager, Harry, Shanholtz, Carl, Shapiro, Nathan, Schrantz, Stephen J., Thomsen, Isaac, Vermillion, Krista K., Bernard, Gordon R., Rice, Todd W.

Volltext

Lessons from rare maladies: leukocyte adhesion deficiency syndromes von Harris, Estelle S, Weyrich, Andrew S, Zimmerman, Guy A

Volltext

In Vivo Platelet Activation in Critically III Patients With Primary 2009 Influenza A(H1N1) von RONDINA, Matthew T, BREWSTER, Breanna, GRISSOM, Colin K, ZIMMERMAN, Guy A, KASTENDIECK, Diana H, HARRIS, Estelle S, WEYRICH, Andrew S

Volltext

Neutralizing COVID-19 Convalescent Plasma in Adults Hospitalized With COVID-19: A Blinded, Randomized, Placebo-Controlled Trial von Self, Wesley H, Wheeler, Allison P, Stewart, Thomas G, Schrager, Harry, Mallada, Jason, Thomas, Christopher B, Cataldo, Vince D, O'Neal, Jr, Hollis R, Shapiro, Nathan I, Higgins, Conor, Ginde, Adit A, Chauhan, Lakshmi, Johnson, Nicholas J, Henning, Daniel J, Jaiswal, Stuti J, Mammen, Manoj J, Harris, Estelle S, Pannu, Sonal R, Laguio-Vila, Maryrose, El Atrouni, Wissam, de Wit, Marjolein, Hoda, Daanish, Cohn, Claudia S, McWilliams, Carla, Shanholtz, Carl, Jones, Alan E, Raval, Jay S, Mucha, Simon, Ipe, Tina S, Qiao, Xian, Schrantz, Stephen J, Shenoy, Aarthi, Fremont, Richard D, Brady, Eric J, Carnahan, Robert H, Chappell, James D, Crowe, Jr, James E, Denison, Mark R, Gilchuk, Pavlo, Stevens, Laura J, Sutton, Rachel E, Thomsen, Isaac, Yoder, Sandra M, Bistran-Hall, Amanda J, Casey, Jonathan D, Lindsell, Christopher J, Wang, Li, Pulley, Jill M, Rhoads, Jillian P, Bernard, Gordon R, Rice, Todd W

Volltext

Acetaminophen for Prevention and Treatment of Organ Dysfunction in Critically Ill Patients With Sepsis: The ASTER Randomized Clinical Trial von Ware, Lorraine B, Files, D. Clark, Fowler, Alpha, Aboodi, Michael S, Aggarwal, Neil R, Brower, Roy G, Chang, Steven Y, Douglas, Ivor S, Fields, Scott, Foulkes, Andrea S, Ginde, Adit A, Harris, Estelle S, Hendey, Gregory W, Hite, R. Duncan, Huang, Weixing, Lai, Poying, Liu, Kathleen D, Thompson, B. Taylor, Matthay, Michael A

Volltext

Inhaled Sargramostim (Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor) for COVID-19-Associated Acute Hypoxemia: Results of the Phase 2, Randomized, Open-Label Tr... von Paine, Robert, Chasse, Robert, Halstead, E Scott, Nfonoyim, Jay, Park, David J, Byun, Timothy, Patel, Bela, Molina-Pallete, Guido, Harris, Estelle S, Garner, Fiona, Simms, Lorinda, Ahuja, Sanjeev, McManus, John L, Roychowdhury, Debasish F

Volltext

Platelet-monocyte aggregate formation and mortality risk in older patients with severe sepsis and septic shock von Rondina, Matthew T, Carlisle, McKenzie, Fraughton, Tamra, Brown, Samuel M, Miller, 3rd, Russell R, Harris, Estelle S, Weyrich, Andrew S, Zimmerman, Guy A, Supiano, Mark A, Grissom, Colin K

Volltext

Assessment and mitigation of bias in influenza and COVID-19 vaccine effectiveness analyses — IVY Network, September 1, 2022–March 30, 2023 von Lewis, Nathaniel M., Harker, Elizabeth J., Leis, Aleda, Zhu, Yuwei, Talbot, H. Keipp, Grijalva, Carlos G., Halasa, Natasha, Chappell, James D., Johnson, Cassandra A., Rice, Todd W., Casey, Jonathan D., Lauring, Adam S., Gaglani, Manjusha, Ghamande, Shekhar, Columbus, Cristie, Steingrub, Jay S., Shapiro, Nathan I., Duggal, Abhijit, Felzer, Jamie, Prekker, Matthew E., Peltan, Ithan D., Brown, Samuel M., Hager, David N., Gong, Michelle N., Mohamed, Amira, Exline, Matthew C., Khan, Akram, Wilson, Jennifer G., Mosier, Jarrod, Qadir, Nida, Chang, Steven Y., Ginde, Adit A., Mohr, Nicholas M., Mallow, Christopher, Harris, Estelle S., Johnson, Nicholas J., Srinivasan, Vasisht, Gibbs, Kevin W., Kwon, Jennie H., Vaughn, Ivana A., Ramesh, Mayur, Safdar, Basmah, DeCuir, Jennifer, Surie, Diya, Dawood, Fatimah S., Ellington, Sascha, Self, Wesley H., Martin, Emily T.

Volltext

Hydroxychloroquine versus Azithromycin for Hospitalized Patients with Suspected or Confirmed COVID-19 (HAHPS) Protocol for a Pragmatic, Open-Label, Active Comparator Trial von Brown, Samuel M., Peltan, Ithan D., Webb, Brandon, Kumar, Naresh, Starr, Nathan, Grissom, Colin, Buckel, Whitney R., Srivastava, Raj, Harris, Estelle S., Leither, LindsayM, Johnson, Stacy A., Paine, Robert, Greene, Tom

Volltext

A novel syndrome of variant leukocyte adhesion deficiency involving defects in adhesion mediated by β1 and β2 integrins von Harris, Estelle S., Shigeoka, Ann O., Li, Wenhua, Adams, Roberta H., Prescott, Stephen M., McIntyre, Thomas M., Zimmerman, Guy A., Lorant, Diane E.

Volltext

Sepsis with liver dysfunction and coagulopathy predicts an inflammatory pattern of macrophage activation von Anderko, Renee R., Gómez, Hernando, Canna, Scott W., Shakoory, Bita, Angus, Derek C., Yealy, Donald M., Huang, David T., Kellum, John A., Carcillo, Joseph A.

Volltext

Whole blood flow cytometry measurements of in vivo platelet activation in critically-Ill patients are influenced by variability in blood sampling techniques von Rondina, Matthew T, Grissom, Colin K, Men, Shaohua, Harris, Estelle S, Schwertz, Hansjorg, Zimmerman, Guy A, Weyrich, Andrew S

Volltext

Interim Effectiveness of Updated 2023-2024 (Monovalent XBB.1.5) COVID-19 Vaccines Against COVID-19-Associated Emergency Department and Urgent Care Encounters and Hospitalization Am... von DeCuir, Jennifer, Payne, Amanda B, Self, Wesley H, Rowley, Elizabeth A K, Dascomb, Kristin, DeSilva, Malini B, Irving, Stephanie A, Grannis, Shaun J, Ong, Toan C, Klein, Nicola P, Weber, Zachary A, Reese, Sarah E, Ball, Sarah W, Barron, Michelle A, Naleway, Allison L, Dixon, Brian E, Essien, Inih, Bride, Daniel, Natarajan, Karthik, Fireman, Bruce, Shah, Ami B, Okwuazi, Erica, Wiegand, Ryan, Zhu, Yuwei, Lauring, Adam S, Martin, Emily T, Gaglani, Manjusha, Peltan, Ithan D, Brown, Samuel M, Ginde, Adit A, Mohr, Nicholas M, Gibbs, Kevin W, Hager, David N, Prekker, Matthew, Mohamed, Amira, Srinivasan, Vasisht, Steingrub, Jay S, Khan, Akram, Busse, Laurence W, Duggal, Abhijit, Wilson, Jennifer G, Chang, Steven Y, Mallow, Christopher, Kwon, Jennie H, Exline, Matthew C, Columbus, Cristie, Vaughn, Ivana A, Safdar, Basmah, Mosier, Jarrod M, Harris, Estelle S, Casey, Jonathan D, Chappell, James D, Grijalva, Carlos G, Swan, Sydney A, Johnson, Cassandra, Lewis, Nathaniel M, Ellington, Sascha, Adams, Katherine, Tenforde, Mark W, Paden, Clinton R, Dawood, Fatimah S, Fleming-Dutra, Katherine E, Surie, Diya, Link-Gelles, Ruth

Volltext

Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial von Sevransky, Jonathan E, Rothman, Richard E, Hager, David N, Bernard, Gordon R, Brown, Samuel M, Buchman, Timothy G, Busse, Laurence W, Coopersmith, Craig M, DeWilde, Christine, Ely, E. Wesley, Eyzaguirre, Lindsay M, Fowler, Alpha A, Gaieski, David F, Gong, Michelle N, Hall, Alex, Hinson, Jeremiah S, Hooper, Michael H, Kelen, Gabor D, Khan, Akram, Levine, Mark A, Lewis, Roger J, Lindsell, Chris J, Marlin, Jessica S, McGlothlin, Anna, Moore, Brooks L, Nugent, Katherine L, Nwosu, Samuel, Polito, Carmen C, Rice, Todd W, Ricketts, Erin P, Rudolph, Caroline C, Sanfilippo, Fred, Viele, Kert, Martin, Greg S, Wright, David W

Volltext