Combination of Wnt/β-Catenin Targets S100A4 and DKK1 Improves Prognosis of Human Colorectal Cancer von Dahlmann, Mathias, Monks, Anne, Harris, Erik D, Kobelt, Dennis, Osterland, Marc, Khaireddine, Fadi, Herrmann, Pia, Kemmner, Wolfgang, Burock, Susen, Walther, Wolfgang, Shoemaker, Robert H, Stein, Ulrike

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The Metastasis-Associated Gene S100A4 Is a Novel Target of β-catenin/T-cell Factor Signaling in Colon Cancer von Stein, Ulrike, Arlt, Franziska, Walther, Wolfgang, Smith, Janice, Waldman, Todd, Harris, Erik D., Mertins, Susan D., Heizmann, Claus W., Allard, David, Birchmeier, Walter, Schlag, Peter M., Shoemaker, Robert H.

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UCN-01 enhances the in vitro toxicity of clinical agents in human tumor cell lines von Monks, A, Harris, E D, Vaigro-Wolff, A, Hose, C D, Connelly, J W, Sausville, E A

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Abstract 154: Establishment and characterization of a novel clear cell sarcoma organoid model derived from a human biopsy von Campbell, Petreena S., Harris, Erik D., Moore, Nancy, Parchment, Ralph E., Coussens, Nathan P., Teicher, Beverly A., Chen, Alice, Doroshow, James H., Rapisarda, Annamaria

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Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529 von Zhou, Tongqing, Wang, Lingshu, Misasi, John, Pegu, Amarendra, Zhang, Yi, Harris, Darcy R, Olia, Adam S, Talana, Chloe Adrienna, Yang, Eun Sung, Chen, Man, Choe, Misook, Shi, Wei, Teng, I-Ting, Creanga, Adrian, Jenkins, Claudia, Leung, Kwanyee, Liu, Tracy, Stancofski, Erik-Stephane D, Stephens, Tyler, Zhang, Baoshan, Tsybovsky, Yaroslav, Graham, Barney S, Mascola, John R, Sullivan, Nancy J, Kwong, Peter D

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Clinical indicators for common paediatric conditions: Processes, provenance and products of the CareTrack Kids study von Wiles, Louise K, Hooper, Tamara D, Hibbert, Peter D, Molloy, Charlotte, White, Les, Jaffe, Adam, Cowell, Christopher T, Harris, Mark F, Runciman, William B, Schmiede, Annette, Dalton, Chris, Hallahan, Andrew R, Dalton, Sarah, Williams, Helena, Wheaton, Gavin, Murphy, Elisabeth, Braithwaite, Jeffrey

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Population Genomics Reveal Recent Speciation and Rapid Evolutionary Adaptation in Polar Bears von Liu, Shiping, Lorenzen, Eline D., Fumagalli, Matteo, Li, Bo, Harris, Kelley, Xiong, Zijun, Zhou, Long, Korneliussen, Thorfinn Sand, Somel, Mehmet, Babbitt, Courtney, Wray, Greg, Li, Jianwen, He, Weiming, Wang, Zhuo, Fu, Wenjing, Xiang, Xueyan, Morgan, Claire C., Doherty, Aoife, O’Connell, Mary J., McInerney, James O., Born, Erik W., Dalén, Love, Dietz, Rune, Orlando, Ludovic, Sonne, Christian, Zhang, Guojie, Nielsen, Rasmus, Willerslev, Eske, Wang, Jun

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Asymmetric introgression reveals the genetic architecture of a plumage trait von Semenov, Georgy A., Linck, Ethan, Enbody, Erik D., Harris, Rebecca B., Khaydarov, David R., Alström, Per, Andersson, Leif, Taylor, Scott A.

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Interacting networks of resistance, virulence and core machinery genes identified by genome-wide epistasis analysis von Skwark, Marcin J, Croucher, Nicholas J, Puranen, Santeri, Chewapreecha, Claire, Pesonen, Maiju, Xu, Ying Ying, Turner, Paul, Harris, Simon R, Beres, Stephen B, Musser, James M, Parkhill, Julian, Bentley, Stephen D, Aurell, Erik, Corander, Jukka

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Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA von Bergstrom, Erik N., Luebeck, Jens, Petljak, Mia, Khandekar, Azhar, Barnes, Mark, Zhang, Tongwu, Steele, Christopher D., Pillay, Nischalan, Landi, Maria Teresa, Bafna, Vineet, Mischel, Paul S., Harris, Reuben S., Alexandrov, Ludmil B.

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Persistent Blood Stream Infection in Patients Supported With a Continuous-Flow Left Ventricular Assist Device Is Associated With an Increased Risk of Cerebrovascular Accidents von Trachtenberg, Barry H., MD, Cordero-Reyes, Andrea M., MD, Aldeiri, Molham, MD, Alvarez, Paulino, MD, Bhimaraj, Arvind, MD, Ashrith, Guha, MD, Elias, Barbara, RN, Suarez, Erik E., MD, Bruckner, Brian, MD, Loebe, Matthias, MD, Harris, Richard L., MD, Zhang, J. Yi, MD, Torre-Amione, Guillermo, MD, PhD, Estep, Jerry D., MD

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Whole-Genome Resequencing Reveals Extensive Natural Variation in the Model Green Alga Chlamydomonas reinhardtii von Flowers, Jonathan M., Hazzouri, Khaled M., Pham, Gina M., Rosas, Ulises, Bahmani, Tayebeh, Khraiwesh, Basel, Nelson, David R., Jijakli, Kenan, Abdrabu, Rasha, Harris, Elizabeth H., Lefebvre, Paul A., Hom, Erik F.Y., Salehi-Ashtiani, Kourosh, Purugganan, Michael D.

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Pivotal Advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis von Andersson, Åsa, Covacu, Ruxandra, Sunnemark, Dan, Danilov, Alexandre I., Bianco, Assunta, Khademi, Mohsen, Wallström, Erik, Lobell, Anna, Brundin, Lou, Lassmann, Hans, Harris, Robert A.

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ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial von Wrangle, John M, Velcheti, Vamsidhar, Patel, Manish R, Garrett-Mayer, Elizabeth, Hill, Elizabeth G, Ravenel, James G, Miller, Jeffrey S, Farhad, Mohammad, Anderton, Kate, Lindsey, Kathryn, Taffaro-Neskey, Michele, Sherman, Carol, Suriano, Samantha, Swiderska-Syn, Marzena, Sion, Amy, Harris, Joni, Edwards, Andie R, Rytlewski, Julie A, Sanders, Catherine M, Yusko, Erik C, Robinson, Mark D, Krieg, Carsten, Redmond, William L, Egan, Jack O, Rhode, Peter R, Jeng, Emily K, Rock, Amy D, Wong, Hing C, Rubinstein, Mark P

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Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial von Pahor, Marco, Guralnik, Jack M, Ambrosius, Walter T, Blair, Steven, Bonds, Denise E, Church, Timothy S, Espeland, Mark A, Fielding, Roger A, Gill, Thomas M, Groessl, Erik J, King, Abby C, Kritchevsky, Stephen B, Manini, Todd M, McDermott, Mary M, Miller, Michael E, Newman, Anne B, Rejeski, W. Jack, Sink, Kaycee M, Williamson, Jeff D

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Persistence of hSBA titers elicited by the meningococcal serogroup B vaccine menB-FHbp for up to 4 years after a 2- or 3-dose primary series and immunogenicity, safety, and tolerab... von Østergaard, Lars, Vesikari, Timo, Senders, Shelly D., Flodmark, Carl-Erik, Kosina, Pavel, Jiang, Han-Qing, Maguire, Jason D., Absalon, Judith, Jansen, Kathrin U., Harris, Shannon L., Maansson, Roger, Balmer, Paul, Beeslaar, Johannes, Perez, John L.

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Genome-wide coancestry reveals details of ancient and recent male-driven reticulation in baboons von Sørensen, Erik F, Harris, R Alan, Zhang, Liye, Raveendran, Muthuswamy, Kuderna, Lukas F K, Walker, Jerilyn A, Storer, Jessica M, Kuhlwilm, Martin, Fontsere, Claudia, Seshadri, Lakshmi, Bergey, Christina M, Burrell, Andrew S, Bergman, Juraj, Phillips-Conroy, Jane E, Shiferaw, Fekadu, Chiou, Kenneth L, Chuma, Idrissa S, Keyyu, Julius D, Fischer, Julia, Gingras, Marie-Claude, Salvi, Sejal, Doddapaneni, Harshavardhan, Schierup, Mikkel H, Batzer, Mark A, Jolly, Clifford J, Knauf, Sascha, Zinner, Dietmar, Farh, Kyle K-H, Marques-Bonet, Tomas, Munch, Kasper, Roos, Christian, Rogers, Jeffrey

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Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha von Olmez, Inan, Love, Shawn, Xiao, Aizhen, Manigat, Laryssa, Randolph, Peyton, McKenna, Brian D, Neal, Brian P, Boroda, Salome, Li, Ming, Brenneman, Breanna, Abounader, Roger, Floyd, Desiree, Lee, Jeongwu, Nakano, Ichiro, Godlewski, Jakub, Bronisz, Agnieszka, Sulman, Erik P, Mayo, Marty, Gioeli, Daniel, Weber, Michael, Harris, Thurl E, Purow, Benjamin

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Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes von Chauhan, Ganesh, Traylor, Matthew, Sargurupremraj, Muralidharan, Okada, Yukinori, Mishra, Aniket, Giese, Anne-Katrin, van der Laan, Sander W., Gretarsdottir, Solveig, Anderson, Christopher D., Almgren, Peter, Amouyel, Philippe, Bartz, Traci M., Benavente, Oscar R., Boncoraglio, Giorgio B., Butterworth, Adam S., Carrera, Caty, Chasman, Daniel I., Cotlarciuc, Ioana, Cruchaga, Carlos, de Bakker, Paul I. W., Duan, Qing, Gottesman, Rebecca F., Harris, Tamara B., Hassan, Ahamad, Havulinna, Aki S., Heckbert, Susan R., Hyacinth, Hyacinth I., Ikram, M. Arfan, Ingelsson, Erik, Jian, Xueqiu, Jukema, J. Wouter, Kanai, Masahiro, Keene, Keith L., Kissela, Brett M., Kleindorfer, Dawn O., Kooperberg, Charles, Lange, Leslie A., Langenberg, Claudia, Launer, Lenore J., Lemmens, Robin, Lewis, Cathryn M., Lin, Wei-Yu, Lorentzen, Erik, Magnusson, Patrik K., Meschia, James F., Mitchell, Braxton D., Mosley, Thomas H., Nalls, Michael A., O’Donnell, Martin J., Pulit, Sara L., Reiner, Alexander P., Ridker, Paul M., Rothwell, Peter M., Rotter, Jerome I., Sale, Michele M., Salomaa, Veikko, Sapkota, Bishwa R., Schmidt, Reinhold, Schmidt, Carsten O., Sharma, Pankaj, Slowik, Agnieszka, Sudlow, Cathie L. M., Tanislav, Christian, Thijs, Vincent N. S., Thorsteinsdottir, Unnur, Tiedt, Steffen, Trompet, Stella, Wareham, Nicholas J., Wassertheil-Smoller, Sylvia, Wilson, James G., Pastinen, Tomi, Ruusalepp, Arno, Koplev, Simon, Björkegren, Johan L. M., Codoni, Veronica, Civelek, Mete, Christophersen, Ingrid E., Roselli, Carolina, Ellinor, Patrick T., Kato, Norihiro, van der Harst, Pim, Elliott, Paul, Takeuchi, Fumihiko, Johnson, Andrew D., Sanghera, Dharambir K., Melander, Olle, Strbian, Daniel, Fernandez-Cadenas, Israel, Rolfs, Arndt, Hata, Jun, Woo, Daniel, Pare, Guillaume, Hopewell, Jemma C., Saleheen, Danish, Stefansson, Kari, Worrall, Bradford B., Seshadri, Sudha, Markus, Hugh S., Debette, Stephanie, Dichgans, Martin

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GBT/Argus Observations of Molecular Gas in the Inner Regions of IC 342 von Li, Jialu, Harris, Andrew I., Rosolowsky, Erik, Kepley, Amanda A., Frayer, David, Bolatto, Alberto D., Leroy, Adam K., Donovan Meyer, Jennifer, Church, Sarah, Gundersen, Joshua Ott, Cleary, Kieran

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