Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies von Kelly, Jennifer A, Harley, Isaac T. W, Kaufman, Kenneth M, Langefeld, Carl D, Harley, John B

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SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression von Hou, Guojun, Harley, Isaac T. W., Lu, Xiaoming, Zhou, Tian, Xu, Ning, Yao, Chao, Qin, Yuting, Ouyang, Ye, Ma, Jianyang, Zhu, Xinyi, Yu, Xiang, Xu, Hong, Dai, Dai, Ding, Huihua, Yin, Zhihua, Ye, Zhizhong, Deng, Jun, Zhou, Mi, Tang, Yuanjia, Namjou, Bahram, Guo, Ya, Weirauch, Matthew T., Kottyan, Leah C., Harley, John B., Shen, Nan

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GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network von Namjou, Bahram, Lingren, Todd, Huang, Yongbo, Parameswaran, Sreeja, Cobb, Beth L, Stanaway, Ian B, Connolly, John J, Mentch, Frank D, Benoit, Barbara, Niu, Xinnan, Wei, Wei-Qi, Carroll, Robert J, Pacheco, Jennifer A, Harley, Isaac T W, Divanovic, Senad, Carrell, David S, Larson, Eric B, Carey, David J, Verma, Shefali, Ritchie, Marylyn D, Gharavi, Ali G, Murphy, Shawn, Williams, Marc S, Crosslin, David R, Jarvik, Gail P, Kullo, Iftikhar J, Hakonarson, Hakon, Li, Rongling, Xanthakos, Stavra A, Harley, John B

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A BAFF/APRIL axis regulates obesogenic diet-driven weight gain von Chan, Calvin C., Harley, Isaac T. W., Pfluger, Paul T., Trompette, Aurelien, Stankiewicz, Traci E., Allen, Jessica L., Moreno-Fernandez, Maria E., Damen, Michelle S. M. A., Oates, Jarren R., Alarcon, Pablo C., Doll, Jessica R., Flick, Matthew J., Flick, Leah M., Sanchez-Gurmaches, Joan, Mukherjee, Rajib, Karns, Rebekah, Helmrath, Michael, Inge, Thomas H., Weisberg, Stuart P., Pamp, Sünje J., Relman, David A., Seeley, Randy J., Tschöp, Matthias H., Karp, Christopher L., Divanovic, Senad

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Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease von Wills-Karp, Marsha, Chen, Jing, Knowles, Michael R, Flick, Leah M, Gu, YuanYuan, Thio, Chloe L, Huber, Lukas A, Ewart, Susan L, Vietor, Ilja, Williams, Adrienne H, Drumm, Mitchell L, Karp, Christopher L, Harley, Isaac T. W, Arshad, S. Hasan, Grimes, H. Leighton, Henderson, Lindsay B, Harley, John B, Langefeld, Carl D, Kilpatrick, Jeffrey R, Filippi, Marie-Dominique, Cutting, Garry R, Aronow, Bruce J, Jegga, Anil G

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The effect of inversion at 8p23 on BLK association with lupus in Caucasian population von Namjou, Bahram, Ni, Yizhao, Harley, Isaac T W, Chepelev, Iouri, Cobb, Beth, Kottyan, Leah C, Gaffney, Patrick M, Guthridge, Joel M, Kaufman, Kenneth, Harley, John B

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Osteopontin and systemic lupus erythematosus association: a probable gene-gender interaction von Han, Shizhong, Guthridge, Joel M, Harley, Isaac T W, Sestak, Andrea L, Kim-Howard, Xana, Kaufman, Kenneth M, Namjou, Bahram, Deshmukh, Harshal, Bruner, Gail, Espinoza, Luis R, Gilkeson, Gary S, Harley, John B, James, Judith A, Nath, Swapan K

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IL‐17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice von Harley, Isaac T.W., Stankiewicz, Traci E., Giles, Daniel A., Softic, Samir, Flick, Leah M., Cappelletti, Monica, Sheridan, Rachel, Xanthakos, Stavra A., Steinbrecher, Kris A., Sartor, R. Balfour, Kohli, Rohit, Karp, Christopher L., Divanovic, Senad

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Polygenic autoimmune disease risk alleles impacting B cell tolerance act in concert across shared molecular networks in mouse and in humans von Harley, Isaac T W, Allison, Kristen, Scofield, R Hal

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Characterization of cxorf21 Provides Molecular Insight Into Female-Bias Immune Response in SLE Pathogenesis von Harris, Valerie M, Koelsch, Kristi A, Kurien, Biji T, Harley, Isaac T W, Wren, Jonathan D, Harley, John B, Scofield, R Hal

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Lysosomal pH Is Regulated in a Sex Dependent Manner in Immune Cells Expressing CXorf21 von Harris, Valerie M, Harley, Isaac T W, Kurien, Biji T, Koelsch, Kristi A, Scofield, Robert Hal

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Pervasive Sharing of Causal Genetic Risk Factors Contributes to Clinical and Molecular Overlap between Sjögren's Disease and Systemic Lupus Erythematosus von Chau, Karen, Raksadawan, Yanint, Allison, Kristen, Ice, John A, Scofield, Robert Hal, Chepelev, Iouri, Harley, Isaac T W

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Comparative analysis of the repertoire of insulin-reactive B cells in type 1 diabetes-prone and resistant mice von Banach, Maureen, Harley, Isaac T. W., Getahun, Andrew, Cambier, John C.

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Inhibitory Receptor Trap: A Platform for Discovery of Inhibitory Receptors That Utilize Inositol Lipid and Phosphotyrosine Phosphatase Effectors von Crute, Bergren W., Sheraden, Rachel, Ott, Vanessa L., Harley, Isaac T. W., Getahun, Andrew, Cambier, John C.

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Systemic lupus erythematosus as a genetic disease von Harley, Isaac T.W., Sawalha, Amr H.

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Magnetic Enrichment of SARS-CoV-2 Antigen-Binding B Cells for Analysis of Transcriptome and Antibody Repertoire von Banach, Maureen, Harley, Isaac T. W., McCarthy, Mary K., Rester, Cody, Stassinopoulos, Adonis, Kedl, Ross M., Morrison, Thomas E., Cambier, John C.

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Association between systemic lupus erythematosus and myasthenia gravis: A population-based National Study von Igoe, Ann, Merjanah, Sali, Harley, Isaac T.W., Clark, Dennis H., Sun, Celi, Kaufman, Kenneth M., Harley, John B., Kaelber, David C., Scofield, R. Hal

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Identification of ATPAF1 as a novel candidate gene for asthma in children von Schauberger, Eric M., BS, Ewart, Susan L., DVM, PhD, Arshad, Syed H., DM, FRCP, Huebner, Marianne, PhD, Karmaus, Wilfried, MD, DrMed, MPH, Holloway, John W., PhD, Friderici, Karen H., PhD, Ziegler, Julie T., MA, Zhang, Hongmei, PhD, Rose-Zerilli, Matthew J., BSc, Barton, Sheila J., MSc, Holgate, Stephen T., MD, DSc, FMed Sci, Kilpatrick, Jeffrey R., BS, Harley, John B., MD, PhD, Lajoie-Kadoch, Stephane, PhD, Harley, Isaac T.W., BS, Hamid, Qutayba, MD, PhD, Kurukulaaratchy, Ramesh J., DM, MRCP, Seibold, Max A., PhD, Avila, Pedro C., MD, Rodriguez-Cintrón, William, MD, Rodriguez-Santana, Jose R., MD, Hu, Donglei, PhD, Gignoux, Christopher, MS, Romieu, Isabelle, MD, MPH, ScD, London, Stephanie J., MD, DrPH, MPH, Burchard, Esteban G., MD, MPH, Langefeld, Carl D., PhD, Wills-Karp, Marsha, PhD

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The Role of Genetic Variation Near Interferon-Kappa in Systemic Lupus Erythematosus von Divers, Jasmin, Bruner, Gail R., Edberg, Jeffrey C., Hutchings, David, Kilpatrick, Jeffrey R., Kelly, Jennifer A., Franek, Beverly S., Glenn, Stuart B., Kaufman, Kenneth M., Stormont, Rebecca M., Niewold, Timothy B., Harley, Isaac T. W., McGwin, Gerald, Petri, Michelle A., Ramsey-Goldman, Rosalind, Reveille, John D., Vilá-Pérez, Luis M., Merrill, Joan T., Gilkeson, Gary S., Vyse, Timothy J., Alarcón-Riquelme, Marta E., Cho, Soo-Kyung, Jacob, Chaim O., Alarcón, Graciela S., Moser, Kathy L., Gaffney, Patrick M., Kimberly, Robert P., Bae, Sang-Cheol, Langefeld, Carl D., Harley, John B., Guthridge, Joel M., James, Judith A.

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Obesity and the gut microbiome: Striving for causality von Harley, Isaac T.W, Karp, Christopher L

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