Obesity and the gut microbiome: Striving for causality von Harley, Isaac T.W, Karp, Christopher L

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IL‐17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice von Harley, Isaac T.W., Stankiewicz, Traci E., Giles, Daniel A., Softic, Samir, Flick, Leah M., Cappelletti, Monica, Sheridan, Rachel, Xanthakos, Stavra A., Steinbrecher, Kris A., Sartor, R. Balfour, Kohli, Rohit, Karp, Christopher L., Divanovic, Senad

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Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies von Kelly, Jennifer A, Harley, Isaac T. W, Kaufman, Kenneth M, Langefeld, Carl D, Harley, John B

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Differential colonization with segmented filamentous bacteria and Lactobacillus murinus do not drive divergent development of diet-induced obesity in C57BL/6 mice von Harley, Isaac T.W, Giles, Daniel A, Pfluger, Paul T, Burgess, Stacey L, Walters, Stephanie, Hembree, Jazzminn, Raver, Christine, Rewerts, Cheryl L, Downey, Jordan, Flick, Leah M, Stankiewicz, Traci E, McAlees, Jaclyn W, Wills-Karp, Marsha, Balfour Sartor, R, Divanovic, Senad, Tschöp, Matthias H, Karp, Christopher L

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Systemic lupus erythematosus as a genetic disease von Harley, Isaac T.W., Sawalha, Amr H.

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Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease von Wills-Karp, Marsha, Chen, Jing, Knowles, Michael R, Flick, Leah M, Gu, YuanYuan, Thio, Chloe L, Huber, Lukas A, Ewart, Susan L, Vietor, Ilja, Williams, Adrienne H, Drumm, Mitchell L, Karp, Christopher L, Harley, Isaac T. W, Arshad, S. Hasan, Grimes, H. Leighton, Henderson, Lindsay B, Harley, John B, Langefeld, Carl D, Kilpatrick, Jeffrey R, Filippi, Marie-Dominique, Cutting, Garry R, Aronow, Bruce J, Jegga, Anil G

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SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression von Hou, Guojun, Harley, Isaac T. W., Lu, Xiaoming, Zhou, Tian, Xu, Ning, Yao, Chao, Qin, Yuting, Ouyang, Ye, Ma, Jianyang, Zhu, Xinyi, Yu, Xiang, Xu, Hong, Dai, Dai, Ding, Huihua, Yin, Zhihua, Ye, Zhizhong, Deng, Jun, Zhou, Mi, Tang, Yuanjia, Namjou, Bahram, Guo, Ya, Weirauch, Matthew T., Kottyan, Leah C., Harley, John B., Shen, Nan

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GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network von Namjou, Bahram, Lingren, Todd, Huang, Yongbo, Parameswaran, Sreeja, Cobb, Beth L, Stanaway, Ian B, Connolly, John J, Mentch, Frank D, Benoit, Barbara, Niu, Xinnan, Wei, Wei-Qi, Carroll, Robert J, Pacheco, Jennifer A, Harley, Isaac T W, Divanovic, Senad, Carrell, David S, Larson, Eric B, Carey, David J, Verma, Shefali, Ritchie, Marylyn D, Gharavi, Ali G, Murphy, Shawn, Williams, Marc S, Crosslin, David R, Jarvik, Gail P, Kullo, Iftikhar J, Hakonarson, Hakon, Li, Rongling, Xanthakos, Stavra A, Harley, John B

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Polygenic autoimmune disease risk alleles impacting B cell tolerance act in concert across shared molecular networks in mouse and in humans von Harley, Isaac T W, Allison, Kristen, Scofield, R Hal

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Association between systemic lupus erythematosus and myasthenia gravis: A population-based National Study von Igoe, Ann, Merjanah, Sali, Harley, Isaac T.W., Clark, Dennis H., Sun, Celi, Kaufman, Kenneth M., Harley, John B., Kaelber, David C., Scofield, R. Hal

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Characterization of cxorf21 Provides Molecular Insight Into Female-Bias Immune Response in SLE Pathogenesis von Harris, Valerie M, Koelsch, Kristi A, Kurien, Biji T, Harley, Isaac T W, Wren, Jonathan D, Harley, John B, Scofield, R Hal

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Lysosomal pH Is Regulated in a Sex Dependent Manner in Immune Cells Expressing CXorf21 von Harris, Valerie M, Harley, Isaac T W, Kurien, Biji T, Koelsch, Kristi A, Scofield, Robert Hal

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Pervasive Sharing of Causal Genetic Risk Factors Contributes to Clinical and Molecular Overlap between Sjögren's Disease and Systemic Lupus Erythematosus von Chau, Karen, Raksadawan, Yanint, Allison, Kristen, Ice, John A, Scofield, Robert Hal, Chepelev, Iouri, Harley, Isaac T W

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Comparative analysis of the repertoire of insulin-reactive B cells in type 1 diabetes-prone and resistant mice von Banach, Maureen, Harley, Isaac T. W., Getahun, Andrew, Cambier, John C.

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A BAFF/APRIL axis regulates obesogenic diet-driven weight gain von Chan, Calvin C., Harley, Isaac T. W., Pfluger, Paul T., Trompette, Aurelien, Stankiewicz, Traci E., Allen, Jessica L., Moreno-Fernandez, Maria E., Damen, Michelle S. M. A., Oates, Jarren R., Alarcon, Pablo C., Doll, Jessica R., Flick, Matthew J., Flick, Leah M., Sanchez-Gurmaches, Joan, Mukherjee, Rajib, Karns, Rebekah, Helmrath, Michael, Inge, Thomas H., Weisberg, Stuart P., Pamp, Sünje J., Relman, David A., Seeley, Randy J., Tschöp, Matthias H., Karp, Christopher L., Divanovic, Senad

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Distinct Tlr4-expressing cell compartments control neutrophilic and eosinophilic airway inflammation von McAlees, J W, Whitehead, G S, Harley, I TW, Cappelletti, M, Rewerts, C L, Holdcroft, A M, Divanovic, S, Wills-Karp, M, Finkelman, F D, Karp, C L, Cook, D N

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Inhibitory Receptor Trap: A Platform for Discovery of Inhibitory Receptors That Utilize Inositol Lipid and Phosphotyrosine Phosphatase Effectors von Crute, Bergren W., Sheraden, Rachel, Ott, Vanessa L., Harley, Isaac T. W., Getahun, Andrew, Cambier, John C.

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Two Functional Lupus-Associated BLK Promoter Variants Control Cell-Type- and Developmental-Stage-Specific Transcription von Guthridge, Joel M., Lu, Rufei, Sun, Harry, Sun, Celi, Wiley, Graham B., Dominguez, Nicolas, Macwana, Susan R., Lessard, Christopher J., Kim-Howard, Xana, Cobb, Beth L., Kaufman, Kenneth M., Kelly, Jennifer A., Langefeld, Carl D., Adler, Adam J., Harley, Isaac T.W., Merrill, Joan T., Gilkeson, Gary S., Kamen, Diane L., Niewold, Timothy B., Brown, Elizabeth E., Edberg, Jeffery C., Petri, Michelle A., Ramsey-Goldman, Rosalind, Reveille, John D., Vilá, Luis M., Kimberly, Robert P., Freedman, Barry I., Stevens, Anne M., Boackle, Susan A., Criswell, Lindsey A., Vyse, Tim J., Behrens, Timothy W., Jacob, Chaim O., Alarcón-Riquelme, Marta E., Sivils, Kathy L., Choi, Jiyoung, Joo, Young Bin, Bang, So-Young, Lee, Hye-Soon, Bae, Sang-Cheol, Shen, Nan, Qian, Xiaoxia, Tsao, Betty P., Scofield, R. Hal, Harley, John B., Webb, Carol F., Wakeland, Edward K., James, Judith A., Nath, Swapan K., Graham, Robert R., Gaffney, Patrick M.

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The effect of inversion at 8p23 on BLK association with lupus in Caucasian population von Namjou, Bahram, Ni, Yizhao, Harley, Isaac T W, Chepelev, Iouri, Cobb, Beth, Kottyan, Leah C, Gaffney, Patrick M, Guthridge, Joel M, Kaufman, Kenneth, Harley, John B

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Magnetic Enrichment of SARS-CoV-2 Antigen-Binding B Cells for Analysis of Transcriptome and Antibody Repertoire von Banach, Maureen, Harley, Isaac T. W., McCarthy, Mary K., Rester, Cody, Stassinopoulos, Adonis, Kedl, Ross M., Morrison, Thomas E., Cambier, John C.

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