Preclinical Evaluation of the Pharmacodynamic Properties of 2,5-Diaziridinyl-3-Hydroxymethyl-6-Methyl-1,4-Benzoquinone von Ward, Timothy H, Danson, Sarah, McGown, Alan T, Ranson, Malcolm, Coe, Nic A, Jayson, Gordon C, Cummings, Jeff, Hargreaves, Robert H J, Butler, John

Volltext

Discovery of Quinolinediones Exhibiting a Heat Shock Response and Angiogenesis Inhibition von Hargreaves, Robert H. J, David, Cynthia L, Whitesell, Luke J, LaBarbera, Daniel V, Jamil, Akmal, Chapuis, Jean C, Skibo, Edward B

Volltext

Relationship between NAD(P)H:quinone oxidoreductase 1 (NQO1) levels in a series of stably transfected cell lines and susceptibility to antitumor quinones von WINSKI, Shannon L, SWANN, Elizabeth, HARGREAVES, Robert H. J, DEHN, Donna L, BUTLER, John, MOODY, Christopher J, ROSS, David

Volltext

A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agen... von WINSKI, S. L, HARGREAVES, R. H. J, BUTLER, J, ROSS, D

Volltext

Cross-Linking and Sequence-Specific Alkylation of DNA by Aziridinylquinones. 3. Effects of Alkyl Substituents von Hargreaves, Robert H. J, O'Hare, C. Caroline, Hartley, John A, Ross, David, Butler, John

Volltext

Relationship between NAD(P)H:quinone oxidoreductase 1 (NQO1) levels in a series of stably transfected cell lines and susceptibility to antitumor quinones 1 2 1In accordance with th... von Winski, Shannon L., Swann, Elizabeth, Hargreaves, Robert H.J., Dehn, Donna L., Butler, John, Moody, Christopher J., Ross, David

Volltext

Development and validation of a sensitive solid-phase extraction and high-performance liquid chromatographic assay for the novel bio-reductive anti-tumor agent RH1 in human and mou... von Khan, Parveen, Abbas, Sayara, Hargreaves, Robert H.J, Caffrey, Robert, Megram, Victoria, McGown, Alan

Volltext

Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530 von Green, Tim P., Fennell, Mike, Whittaker, Robin, Curwen, Jon, Jacobs, Vivien, Allen, Jack, Logie, Armelle, Hargreaves, Judith, Hickinson, D. Mark, Wilkinson, Robert W., Elvin, Paul, Boyer, Brigitte, Carragher, Neil, Plé, Patrick A., Bermingham, Alun, Holdgate, Geoffrey A., Ward, Walter H.J., Hennequin, Laurent F., Davies, Barry R., Costello, Gerard F.

Volltext