Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases von Shio, Marina Tiemi, Tiemi Shio, Marina, Eisenbarth, Stephanie C, Savaria, Myriam, Vinet, Adrien F, Bellemare, Marie-Josée, Harder, Kenneth W, Sutterwala, Fayyaz S, Bohle, D Scott, Descoteaux, Albert, Flavell, Richard A, Olivier, Martin

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Negative regulation of immunoglobulin E-dependent allergic responses by Lyn kinase von Odom, Sandra, Gomez, Gregorio, Kovarova, Martina, Furumoto, Yasuko, Ryan, John J, Wright, Harry V, Gonzalez-Espinosa, Claudia, Hibbs, Margaret L, Harder, Kenneth W, Rivera, Juan

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Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2 von McColl, Bradley K, Paavonen, Karri, Karnezis, Tara, Harris, Nicole C, Davydova, Natalia, Rothacker, Julie, Nice, Edouard C, Harder, Kenneth W, Roufail, Sally, Hibbs, Margaret L, Rogers, Peter A.W, Alitalo, Kari, Stacker, Steven A, Achen, Marc G

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Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity von Hibbs, Margaret L, Harder, Kenneth W, Armes, Jane, Kountouri, Nicole, Quilici, Cathy, Casagranda, Franca, Dunn, Ashley R, Tarlinton, David M

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2B4-SAP signaling is required for the priming of naive CD8+ T cells by antigen-expressing B cells and B lymphoma cells von Huang, Yu-Hsuan, Tsai, Kevin, Tan, Sara Y., Kang, Sohyeong, Ford, Mandy L., Harder, Kenneth W., Priatel, John J.

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Considerations on the design of lipid-based mRNA vaccines against cancer von Meulewaeter, Sofie, Zhang, Yao, Wadhwa, Abishek, Fox, Kevin, Lentacker, Ine, Harder, Kenneth W, Cullis, Pieter R, De Smedt, Stefaan C, H Y Cheng, Miffy, Verbeke, Rein

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Lyn-Deficient Mice Develop Severe, Persistent Asthma: Lyn Is a Critical Negative Regulator of Th2 Immunity von Beavitt, Sarah-Jane E, Harder, Kenneth W, Kemp, Joanna M, Jones, Jessica, Quilici, Cathy, Casagranda, Franca, Lam, Ellen, Turner, Debra, Brennan, Siobhain, Sly, Peter D, Tarlinton, David M, Anderson, Gary P, Hibbs, Margaret L

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Deep Phenotyping by Mass Cytometry and Single-Cell RNA-Sequencing Reveals LYN-Regulated Signaling Profiles Underlying Monocyte Subset Heterogeneity and Lifespan von Roberts, Morgan E., Barvalia, Maunish, Silva, Jessica A.F.D., Cederberg, Rachel A., Chu, William, Wong, Amanda, Tai, Daven C., Chen, Sam, Matos, Israel, Priatel, John J., Cullis, Pieter R., Harder, Kenneth W.

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Cutting Edge: Intestinal Mucus Limits the Clonal Deletion of Developing T Cells Specific for an Oral Antigen von Tsai, Kevin, Huang, Yu-Hsuan, Ma, Caixia, Baldwin, Troy A., Harder, Kenneth W., Vallance, Bruce A., Priatel, John J.

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The role of the Src family kinase Lyn in the immunomodulatory activities of cathelicidin peptide LL-37 on monocytic cells von Nijnik, Anastasia, Pistolic, Jelena, Cho, Patricia, Filewod, Niall C. J., Falsafi, Reza, Ramin, Alexander, Harder, Kenneth W., Hancock, Robert E. W.

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Constitutive activation of the SRC family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response von Ernst, Matthias, Inglese, Melissa, Scholz, Glen M, Harder, Kenneth W, Clay, Fiona J, Bozinovski, Steven, Waring, Paul, Darwiche, Rima, Kay, Tom, Sly, Peter, Collins, Rachel, Turner, Debra, Hibbs, Margaret L, Anderson, Gary P, Dunn, Ashley R

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Lyn Tyrosine Kinase: Accentuating the Positive and the Negative von Xu, Yuekang, Harder, Kenneth W., Huntington, Nicholas D., Hibbs, Margaret L., Tarlinton, David M.

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Dysregulated Hematopoiesis Caused by Mammary Cancer Is Associated with Epigenetic Changes and Hox Gene Expression in Hematopoietic Cells von SIO, Alexander, CHEHAL, Manreet K, TSAI, Kevin, XUELING FAN, ROBERTS, Morgan E, NELSON, Brad H, GREMBECKA, Jolanta, CIERPICKI, Tomasz, KREBS, Danielle L, HARDER, Kenneth W

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An End-to-End Workflow for Interrogating Tumor-Infiltrating Myeloid Cells Using Mass Cytometry von Barvalia, Maunish, Harder, Kenneth W.

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Genetic interdependence of Lyn and negative regulators of B cell receptor signaling in autoimmune disease development von Tsantikos, Evelyn, Maxwell, Mhairi J, Kountouri, Nicole, Harder, Kenneth W, Tarlinton, David M, Hibbs, Margaret L

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Lyn deficiency leads to increased microbiota-dependent intestinal inflammation and susceptibility to enteric pathogens von Roberts, Morgan E, Bishop, Jennifer L, Fan, Xueling, Beer, Jennifer L, Kum, Winnie W S, Krebs, Danielle L, Huang, Morris, Gill, Navkiran, Priatel, John J, Finlay, B Brett, Harder, Kenneth W

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Tumor-derived GCSF Alters Tumor and Systemic Immune System Cell Subset Composition and Signaling von Matos, Israel, Barvalia, Maunish, Chehal, Manreet K, Robertson, A Gordon, Kulic, Iva, Silva, Jessica A F D, Ranganathan, Abhinandan, Short, Amy, Huang, Yu-Hsuan, Long, Erin, Priatel, John J, Dhanji, Salim, Nelson, Brad H, Krebs, Danielle L, Harder, Kenneth W

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Heart and Liver Defects and Reduced Transforming Growth Factor β2 Sensitivity in Transforming Growth Factor β Type III Receptor-Deficient Embryos von Stenvers, Kaye L., Tursky, Melinda L., Harder, Kenneth W., Kountouri, Nicole, Amatayakul-Chantler, Supavadee, Grail, Dianne, Small, Clayton, Weinberg, Robert A., Sizeland, Andrew M., Zhu, Hong-Jian

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The Activation and Subsequent Regulatory Roles of Lyn and CD19 After B Cell Receptor Ligation are Independent von Xu, Yuekang, Beavitt, Sarah-Jane E, Harder, Kenneth W, Hibbs, Margaret L, Tarlinton, David M

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Phosphatidylinositol‐3 kinase activity in B cells is negatively regulated by Lyn tyrosine kinase von Xu, Yuekang, Huntington, Nicholas D, Harder, Kenneth W, Nandurkar, Harshal, Hibbs, Margaret L, Tarlinton, David M

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