Preclinical Evaluation of GS-9160, a Novel Inhibitor of Human Immunodeficiency Virus Type 1 Integrase von JONES, Gregg S, FANG YU, TSIANG, Manuel, ZEYNALZADEGAN, Ameneh, HESSELGESSER, Joseph, XIAOWU CHEN, CHEN, James, HAOLUN JIN, KIM, Choung U, WRIGHT, Matthew, GELEZIUNAS, Romas

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Design, synthesis, and biological evaluation of novel tricyclic HIV-1 integrase inhibitors by modification of its pyridine ring von Metobo, Sammy E., Jin, Haolun, Tsiang, Manuel, Kim, Choung U.

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Prediction of bictegravir human pharmacokinetics from protein binding and in vitro-in vivo correlation von Wang, Jianhong, Lazerwith, Scott, Jin, Haolun, Morganelli, Philip, Pyun, Peter, Tang, Jennifer, Matles, Mike, Mwangi, Judy, Wang, Kelly, Eisenberg, Gene, Murray, Bernard P., Rhodes, Gerry, Zhang, Heather, Custodio, Joseph

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Design, synthesis, and SAR studies of novel and highly active tri-cyclic HIV integrase inhibitors von Jin, Haolun, Cai, Ruby Z., Schacherer, Laura, Jabri, Salman, Tsiang, Manuel, Fardis, Maria, Chen, Xiaowu, Chen, James M., Kim, Choung U.

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Effect of substitution on novel tricyclic HIV-1 integrase inhibitors von Fardis, Maria, Jin, Haolun, Jabri, Salman, Cai, Ruby Z., Mish, Michael, Tsiang, Manuel, Kim, Choung U.

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Tricyclic HIV integrase inhibitors V. SAR studies on the benzyl moiety von Jin, Haolun, Metobo, Sammy, Jabri, Salman, Mish, Michael, Lansdown, Rachael, Chen, Xiaowu, Tsiang, Manuel, Wright, Matthew, Kim, Choung U.

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Tricyclic HIV integrase inhibitors: Potent and orally bioavailable C5-aza analogs von Jin, Haolun, Wright, Matthew, Pastor, Richard, Mish, Michael, Metobo, Sammy, Jabri, Salman, Lansdown, Rachael, Cai, Ruby, Pyun, Peter, Tsiang, Manuel, Chen, Xiaowu, Kim, Choung U.

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Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile von Tsiang, Manuel, Jones, Gregg S, Goldsmith, Joshua, Mulato, Andrew, Hansen, Derek, Kan, Elaine, Tsai, Luong, Bam, Rujuta A, Stepan, George, Stray, Kirsten M, Niedziela-Majka, Anita, Yant, Stephen R, Yu, Helen, Kukolj, George, Cihlar, Tomas, Lazerwith, Scott E, White, Kirsten L, Jin, Haolun

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Discovery of GS-9688 (Selgantolimod) as a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B von Mackman, Richard L, Mish, Michael, Chin, Gregory, Perry, Jason K, Appleby, Todd, Aktoudianakis, Vangelis, Metobo, Sammy, Pyun, Peter, Niu, Congrong, Daffis, Stephane, Yu, Helen, Zheng, Jim, Villasenor, Armando G, Zablocki, Jeff, Chamberlain, Jason, Jin, Haolun, Lee, Gary, Suekawa-Pirrone, Kimberley, Santos, Rex, Delaney, William E, Fletcher, Simon P

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Long Dissociation of Bictegravir from HIV-1 Integrase-DNA Complexes von White, Kirsten L, Osman, Nathan, Cuadra-Foy, Ernesto, Brenner, Bluma G, Shivakumar, Devleena, Campigotto, Federico, Tsiang, Manuel, Morganelli, Philip A, Novikov, Nikolai, Lazerwith, Scott E, Jin, Haolun, Niedziela-Majka, Anita

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Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle von Mackman, Richard L, Steadman, Victoria A, Dean, David K, Jansa, Petr, Poullennec, Karine G, Appleby, Todd, Austin, Carol, Blakemore, Caroline A, Cai, Ruby, Cannizzaro, Carina, Chin, Gregory, Chiva, Jean-Yves C, Dunbar, Neil A, Fliri, Hans, Highton, Adrian J, Hui, Hon, Ji, Mingzhe, Jin, Haolun, Karki, Kapil, Keats, Andrew J, Lazarides, Linos, Lee, Yu-Jen, Liclican, Albert, Mish, Michael, Murray, Bernard, Pettit, Simon B, Pyun, Peter, Sangi, Michael, Santos, Rex, Sanvoisin, Jonathan, Schmitz, Uli, Schrier, Adam, Siegel, Dustin, Sperandio, David, Stepan, George, Tian, Yang, Watt, Gregory M, Yang, Hai, Schultz, Brian E

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Investigation of novel fumagillin analogues as angiogenesis inhibitors von Pyun, Hyung-Jung, Fardis, Maria, Tario, James, Yang, Cheng Y., Ruckman, Judy, Henninger, Dwight, Jin, Haolun, Kim, Choung U.

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Design, synthesis and evaluation of a series of novel fumagillin analogues von FARDIS, Maria, PYUN, Hyung-Jung, TARIO, James, HAOLUN JIN, KIM, Choung U, RUCKMAN, Judy, YUN LIN, GREENS, Louis, HICKED, Brian

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Discovery of 1,6-Naphthyridines as a Novel Class of Potent and Selective Human Cytomegalovirus Inhibitors von Chan, Laval, Jin, Haolun, Stefanac, Tomislav, Lavallée, Jean-François, Falardeau, Guy, Wang, Wei, Bédard, Jean, May, Suzanne, Yuen, Leonard

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Highly Potent HCV NS4B Inhibitors with Activity against Multiple Genotypes von Phillips, Barton, Cai, Ruby, Delaney, William, Du, Zhimin, Ji, Mingzhe, Jin, Haolun, Lee, Johnny, Li, Jiayao, Niedziela-Majka, Anita, Mish, Michael, Pyun, Hyung-Jung, Saugier, Joe, Tirunagari, Neeraj, Wang, Jianhong, Yang, Huiling, Wu, Qiaoyin, Sheng, Chris, Zonte, Catalin

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Antiviral Properties of a Series of 1,6-Naphthyridine and 7,8-Dihydroisoquinoline Derivatives Exhibiting Potent Activity against Human Cytomegalovirus von Bedard, J, May, S, L'Heureux, L, Stamminger, T, Copsey, A, Drach, J, Huffman, J, Chan, L, Jin, H, Rando, R F

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POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE von HAOLUN, Jin

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Highly regioselective ring opening of quinolinic[2,3]anhydrides under mild conditions von Metobo, Sammy E., Jabri, Salman Y., Aktoudianakis, Evangelos, Evans, Jared, Jin, Haolun, Kim, Choung U.

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Anti-Human Immunodeficiency Virus and Anti-Hepatitis-B Virus Activities and Toxicities of the Enantiomers of 2'-Deoxy-3'-oxa-4'-thiocytidine and Their 5-Fluoro Analogs in Vitro von Mansour, Tarek S, Jin, Haolun, Wang, Wei, Hooker, Elizabeth U, Ashman, Clare, Cammack, Nick, Salomon, Horacio, Belmonte, Antonietta R, Wainberg, Mark A

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Design and evaluation of dihydroisoquinolines as potent and orally bioavailable human cytomegalovirus inhibitors von Chan, Laval, Stefanac, Tomislav, Turcotte, Nathalie, Hu, Zhuhan, Chen, Yanmin, Bédard, Jean, May, Suzanne, Jin, Haolun

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