Preparation of (R)-Amines from Racemic Amines with an (S)-Amine Transaminase from Bacillus megaterium von Hanson, Ronald L., Davis, Brian L., Chen, Yijun, Goldberg, Steven L., Parker, William L., Tully, Thomas P., Montana, Michael A., Patel, Ramesh N.

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Preparation of an Amino Acid Intermediate for the Dipeptidyl Peptidase IV Inhibitor, Saxagliptin, using a Modified Phenylalanine Dehydrogenase von Hanson, Ronald L., Goldberg, Steven L., Brzozowski, David B., Tully, Thomas P., Cazzulino, Dana, Parker, William L., Lyngberg, Olav K., Vu, Truc C., Wong, Michael K., Patel, Ramesh N.

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Discovering Drugs through Biological Transformation:  Role of Pharmacologically Active Metabolites in Drug Discovery von Fura, Aberra, Shu, Yue-Zhong, Zhu, Mingshe, Hanson, Ronald L, Roongta, Vikram, Humphreys, W. Griffith

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Enzymatic Preparation of an R‑Amino Acid Intermediate for a γ‑Secretase Inhibitor von Hanson, Ronald L, Johnston, Robert M, Goldberg, Steven L, Parker, William L, Goswami, Animesh

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A Scalable Synthesis of (R,R)‑2,6-Dimethyldihydro‑2H‑pyran-4(3H)‑one von Young, Ian S, Haley, Matthew W, Tam, Annie, Tymonko, Steven A, Xu, Zhongmin, Hanson, Ronald L, Goswami, Animesh

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Efficient and Scalable Enantioselective Synthesis of a CGRP Antagonist von Leahy, David K, Fan, Yu, Desai, Lopa V, Chan, Collin, Zhu, Jason, Luo, Guanglin, Chen, Ling, Hanson, Ronald L, Sugiyama, Masano, Rosner, Thorsten, Cuniere, Nicolas, Guo, Zhiwei, Hsiao, Yi, Gao, Qi

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Discovery of Clinical Candidate 2‑((2S,6S)‑2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3′-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11β-Hydroxysteroid D... von Ye, Xiang-Yang, Chen, Stephanie Y, Wu, Shung, Yoon, David S, Wang, Haixia, Hong, Zhenqiu, O’Connor, Stephen P, Li, Jun, Li, James J, Kennedy, Lawrence J, Walker, Steven J, Nayeem, Akbar, Sheriff, Steven, Camac, Daniel M, Ramamurthy, Vidyhashankar, Morin, Paul E, Zebo, Rachel, Taylor, Joseph R, Morgan, Nathan N, Ponticiello, Randolph P, Harrity, Thomas, Apedo, Atsu, Golla, Rajasree, Seethala, Ramakrishna, Wang, Mengmeng, Harper, Timothy W, Sleczka, Bogdan G, He, Bin, Kirby, Mark, Leahy, David K, Li, Jianqing, Hanson, Ronald L, Guo, Zhiwei, Li, Yi-Xin, DiMarco, John D, Scaringe, Raymond, Maxwell, Brad, Moulin, Frederick, Barrish, Joel C, Gordon, David A, Robl, Jeffrey A

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Biotechnology Based Process for Production of a Disulfide-Bridged Peptide von Goswami, Animesh, Goldberg, Steven L, Hanson, Ronald L, Johnston, Robert M, Lyngberg, Olav K, Chan, Yeung, Lo, Ehrlic, Chan, Steven H, de Mas, Nuria, Ramirez, Antonio, Doyle, Richard, Ding, Wei, Gao, Mian, Krystek, Stanley R, Wan, Changhong, Kim, Yeoun jin, Calambur, Deepa, Witmer, Mark, Bryson, James W

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Enzymatic Reduction of Adamantanones to Chiral Adamantanol Intermediates for the Synthesis of 11-β-Hydroxysteroid Dehydrogenase Inhibitors von Hanson, Ronald L, Goldberg, Steven L, Guo, Zhiwei, Tully, Thomas P, Goswami, Animesh, Ye, Xiang-Yang, Robl, Jeffrey A, Patel, Ramesh N

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Preparation of (S)-1-Cyclopropyl-2-methoxyethanamine by a Chemoenzymatic Route Using Leucine Dehydrogenase von Parker, William L, Hanson, Ronald L, Goldberg, Steven L, Tully, Thomas P, Goswami, Animesh

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Enzymatic Preparation of an (S)-Amino Acid from a Racemic Amino Acid von Chen, Yijun, Goldberg, Steven L, Hanson, Ronald L, Parker, William L, Gill, Iqbal, Tully, Thomas P, Montana, Michael A, Goswami, Animesh, Patel, Ramesh N

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Purification and Cloning of a Ketoreductase used for the Preparation of Chiral Alcohols von Hanson, Ronald L., Goldberg, Steven, Goswami, Animesh, Tully, Thomas P., Patel, Ramesh N.

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Enzymatic Preparation of a d-Amino Acid from a Racemic Amino Acid or Keto Acid von Hanson, Ronald L, Davis, Brian L, Goldberg, Steven L, Johnston, Robert M, Parker, William L, Tully, Thomas P, Montana, Michael A, Patel, Ramesh N

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Selection of an Enantioselective Process for the Preparation of a CGRP Receptor Inhibitor von Cann, Reginald O, Chen, Chung-Pin H, Gao, Qi, Hanson, Ronald L, Hsieh, Daniel, Li, Jun, Lin, Dong, Parsons, Rodney L, Pendri, Yadagiri, Nielsen, R. Brent, Nugent, William A, Parker, William L, Quinlan, Sandra, Reising, Nathan P, Remy, Brenda, Sausker, Justin, Wang, Xuebao

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Enantioselective microbial reduction of 3,5-dioxo-6-(benzyloxy) hexanoic acid, ethyl ester von Patel, Ramesh N., Banerjee, Amit, McNamee, Clyde G., Brzozowski, David, Hanson, Ronald L., Szarka, Laszlo J.

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Enzymatic C-4 deacetylation of 10-deacetylbaccatin III von Hanson, Ronald L., Parker, William L., Patel, Ramesh N.

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Synthesis and activity of a C-8 keto pleuromutilin derivative von Springer, Dane M, Sorenson, Margaret E, Huang, Stella, Connolly, Timothy P, Bronson, Joanne J, Matson, James A, Hanson, Ronald L, Brzozowski, David B, LaPorte, Thomas L, Patel, Ramesh N

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Synthesis of allysine ethylene acetal using phenylalanine dehydrogenase from Thermoactinomyces intermedius von Hanson, Ronald L, Howell, Jeffrey M, LaPorte, Thomas L, Donovan, Mary Jo, Cazzulino, Dana L, Zannella, Valerie, Montana, Michael A, Nanduri, Venkata B, Schwarz, Steven R, Eiring, Ronald F, Durand, Susan C, Wasylyk, John M, Parker, William L, Liu, Mark S, Okuniewicz, Francis J, Chen, Bang-Chi, Harris, John C, Natalie, Kenneth J, Ramig, Keith, Swaminathan, Shankar, Rosso, Victor W, Pack, Shawn K, Lotz, Bruce T, Bernot, Peter J, Rusowicz, Andrew, Lust, David A, Tse, Kai S, Venit, John J, Szarka, Laszlo J, Patel, Ramesh N

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Microbial N-demethylation: biotransformation and recovery of a drug metabolite von Davis, Brian L., Liu, Mark S., Hanson, Ronald L., Parker, William L., Patel, Ramesh N.

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Regioselective enzymatic aminoacylation of lobucavir to give an intermediate for lobucavir prodrug von Hanson, Ronald L, Shi, Zhongping, Brzozowski, David B, Banerjee, Amit, Kissick, Thomas P, Singh, Janak, Pullockaran, Annie J, North, Jeffrey T, Fan, Junying, Howell, Jeffrey, Durand, Susan C, Montana, Michael A, Kronenthal, David R, Mueller, Richard H, Patel, Ramesh N

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