Single Transit Detection in Kepler with Machine Learning and Onboard Spacecraft Diagnostics von Hansen, Matthew T., Dittmann, Jason A.

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Discovery of spirohydantoins as selective, orally bioavailable inhibitors of p300/CBP histone acetyltransferases von Ji, Zhiqin, Clark, Richard F., Bhat, Vikram, Matthew Hansen, T., Lasko, Loren M., Bromberg, Kenneth D., Manaves, Vlasios, Algire, Mikkel, Martin, Ruth, Qiu, Wei, Torrent, Maricel, Jakob, Clarissa G., Liu, Hong, Cole, Philip A., Marmorstein, Ronen, Kesicki, Edward A., Lai, Albert, Michaelides, Michael R.

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Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors von Wilsbacher, Julie L, Cheng, Min, Cheng, Dong, Trammell, Samuel A J, Shi, Yan, Guo, Jun, Koeniger, Stormy L, Kovar, Peter J, He, Yupeng, Selvaraju, Sujatha, Heyman, H Robin, Sorensen, Bryan K, Clark, Richard F, Hansen, T Matthew, Longenecker, Kenton L, Raich, Diana, Korepanova, Alla V, Cepa, Steven, Towne, Danli L, Abraham, Vivek C, Tang, Hua, Richardson, Paul L, McLoughlin, Shaun M, Badagnani, Ilaria, Curtin, Michael L, Michaelides, Michael R, Maag, David, Buchanan, F Gregory, Chiang, Gary G, Gao, Wenqing, Rosenberg, Saul H, Brenner, Charles, Tse, Chris

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Accelerating BAO scale fitting using Taylor series von Hansen, Matthew T, Krolewski, Alex, Slepian, Zachary

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Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients von Yuda, Junichiro, Will, Christine, Phillips, Darren C., Abraham, Linu, Alvey, Cory, Avigdor, Abraham, Buck, Wayne, Besenhofer, Lauren, Boghaert, Erwin, Cheng, Dong, Cojocari, Dan, Doyle, Kelly, Hansen, T. Matthew, Huang, Kevin, Johnson, Eric F., Judd, Andrew S., Judge, Russell A., Kalvass, John C., Kunzer, Aaron, Lam, Lloyd T., Li, Rachel, Martin, Ruth L., Mastracchio, Anthony, Mitten, Mike, Petrich, Adam, Wang, Jin, Ward, James E., Zhang, Haichao, Wang, Xilu, Wolff, Johannes E., Bell-McGuinn, Katherine M., Souers, Andrew J.

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Total Synthesis of Phorboxazole A via de Novo Oxazole Formation: Strategy and Component Assembly von Wang, Bo, Hansen, T. Matthew, Wang, Ting, Wu, Dimao, Weyer, Lynn, Ying, Lu, Engler, Mary M, Sanville, Melissa, Leitheiser, Christopher, Christmann, Mathias, Lu, Yingtao, Chen, Jiehao, Zunker, Nicholas, Cink, Russell D, Ahmed, Feryan, Lee, Chi-Sing, Forsyth, Craig J

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Total Synthesis of Phorboxazole A via de Novo Oxazole Formation: Convergent Total Synthesis von Wang, Bo, Hansen, T. Matthew, Weyer, Lynn, Wu, Dimao, Wang, Ting, Christmann, Mathias, Lu, Yingtao, Ying, Lu, Engler, Mary M, Cink, Russell D, Lee, Chi-Sing, Ahmed, Feryan, Forsyth, Craig J

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Identification and Preliminary Characterization of a Potent, Safe, and Orally Efficacious Inhibitor of Acyl-CoA:Diacylglycerol Acyltransferase 1 von Yeh, Vince S. C, Beno, David W. A, Brodjian, Sevan, Brune, Michael E, Cullen, Steven C, Dayton, Brian D, Dhaon, Madhup K, Falls, Hugh D, Gao, Ju, Grihalde, Nelson, Hajduk, Philip, Hansen, T. Matthew, Judd, Andrew S, King, Andrew J, Klix, Russel C, Larson, Kelly J, Lau, Yau Y, Marsh, Kennan C, Mittelstadt, Scott W, Plata, Dan, Rozema, Michael J, Segreti, Jason A, Stoner, Eric J, Voorbach, Martin J, Wang, Xiaojun, Xin, Xili, Zhao, Gang, Collins, Christine A, Cox, Bryan F, Reilly, Regina M, Kym, Philip R, Souers, Andrew J

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Synthesis and Structure−Activity Relationships of N-{3-[2-(4-Alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy Derivatives as Selective Acetyl-CoA Carboxylase 2 Inhibitors von Gu, Yu Gui, Weitzberg, Moshe, Clark, Richard F, Xu, Xiangdong, Li, Qun, Zhang, Tianyuan, Hansen, T. Matthew, Liu, Gang, Xin, Zhili, Wang, Xiaojun, Wang, Rongqi, McNally, Teresa, Camp, Heidi, Beutel, Bruce A, Sham, Hing L

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Enabling, Decagram-Scale Synthesis of Macrocyclic MCL‑1 Inhibitor ABBV-467 von Brady, Patrick B., Sorensen, Bryan K., Risi, Roberto M., Curtin, Michael L., Mantei, Robert A., Florjancic, Alan S., Mastracchio, Anthony, Ji, Cheng, Kunzer, Aaron R., Lai, Chunqiu, Storer, Gregory E., Chan, Vincent S., Henry, Rodger F., Souers, Andrew J., Michaelides, Michael R., Judd, Andrew S., Hansen, T. Matthew

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Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors von Wang, Le, Pratt, John K, Soltwedel, Todd, Sheppard, George S, Fidanze, Steven D, Liu, Dachun, Hasvold, Lisa A, Mantei, Robert A, Holms, James H, McClellan, William J, Wendt, Michael D, Wada, Carol, Frey, Robin, Hansen, T. Matthew, Hubbard, Robert, Park, Chang H, Li, Leiming, Magoc, Terrance J, Albert, Daniel H, Lin, Xiaoyu, Warder, Scott E, Kovar, Peter, Huang, Xiaoli, Wilcox, Denise, Wang, Rongqi, Rajaraman, Ganesh, Petros, Andrew M, Hutchins, Charles W, Panchal, Sanjay C, Sun, Chaohong, Elmore, Steven W, Shen, Yu, Kati, Warren M, McDaniel, Keith F

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Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases von Michaelides, Michael R, Kluge, Arthur, Patane, Michael, Van Drie, John H, Wang, Ce, Hansen, T. Matthew, Risi, Roberto M, Mantei, Robert, Hertel, Carmen, Karukurichi, Kannan, Nesterov, Alexandre, McElligott, David, de Vries, Peter, Langston, J. William, Cole, Philip A, Marmorstein, Ronen, Liu, Hong, Lasko, Loren, Bromberg, Kenneth D, Lai, Albert, Kesicki, Edward A

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SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT) von Curtin, Michael L., Heyman, H. Robin, Clark, Richard F., Sorensen, Bryan K., Doherty, George A., Hansen, T. Matthew, Frey, Robin R., Sarris, Kathy A., Aguirre, Ana L., Shrestha, Anurupa, Tu, Noah, Woller, Kevin, Pliushchev, Marina A., Sweis, Ramzi F., Cheng, Min, Wilsbacher, Julie L., Kovar, Peter J., Guo, Jun, Cheng, Dong, Longenecker, Kenton L., Raich, Diana, Korepanova, Alla V., Soni, Nirupama B., Algire, Mikkel A., Richardson, Paul L., Marin, Violeta L., Badagnani, Ilaria, Vasudevan, Anil, Buchanan, F. Greg, Maag, David, Chiang, Gary G., Tse, Chris, Michaelides, Michael R.

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Discovery of A‑1331852, a First-in-Class, Potent, and Orally-Bioavailable BCL‑XL Inhibitor von Wang, Le, Doherty, George A, Judd, Andrew S, Tao, Zhi-Fu, Hansen, T. Matthew, Frey, Robin R, Song, Xiaohong, Bruncko, Milan, Kunzer, Aaron R, Wang, Xilu, Wendt, Michael D, Flygare, John A, Catron, Nathaniel D, Judge, Russell A, Park, Chang H, Shekhar, Shashank, Phillips, Darren C, Nimmer, Paul, Smith, Morey L, Tahir, Stephen K, Xiao, Yu, Xue, John, Zhang, Haichao, Le, Phuong N, Mitten, Michael J, Boghaert, Erwin R, Gao, Wenqing, Kovar, Peter, Choo, Edna F, Diaz, Dolores, Fairbrother, Wayne J, Elmore, Steven W, Sampath, Deepak, Leverson, Joel D, Souers, Andrew James

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Synthesis and antibacterial activity of 5-methoxy- and 5-hydroxy-6-fluoro-1,8-naphthyridone-3-carboxylic acid derivatives von Matthew Hansen, T., Gu, Yu-Gui, Rehm, Tamara M., Dandliker, Peter J., Chovan, Linda E., Bui, Mai H., Nilius, Angela M., Beutel, Bruce A.

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A robust in vivo positive-readout system for monitoring siRNA delivery to xenograft tumors von Lin, Xiaoyu, Li, Leiming, Wang, Rongqi, Wilcox, Denise, Zhao, Xiaobin, Song, Jingfeng, Huang, Xiaoli, Hansen, T Matthew, Dande, Prasad, Wada, Carol, Hubbard, Robert D, Kohlbrenner, William M, Fesik, Stephen W, Shen, Yu

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Using Music to Learn Geomorphology: An Undergraduate Experience von Allen, Casey D, Thompson, Tyler J, Hansen, Matthew T

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N-{3-[2-(4-Alkoxyphenoxy)thiazol-5-yl]-1-methylprop-2-ynyl}carboxy Derivatives as Acetyl-CoA Carboxylase InhibitorsImprovement of Cardiovascular and Neurological Liabilities via S... von Gu, Yu Gui, Weitzberg, Moshe, Clark, Richard F, Xu, Xiangdong, Li, Qun, Lubbers, Nathan L, Yang, Yi, Beno, David W. A, Widomski, Deborah L, Zhang, Tianyuan, Hansen, T. Matthew, Keyes, Robert F, Waring, Jeffrey F, Carroll, Sherry L, Wang, Xiaojun, Wang, Rongqi, Healan-Greenberg, Christine H, Blomme, Eric A, Beutel, Bruce A, Sham, Hing L, Camp, Heidi S

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Structure–activity relationships for a novel series of thiazolyl phenyl ether derivatives exhibiting potent and selective acetyl-CoA carboxylase 2 inhibitory activity von Clark, Richard F., Zhang, Tianyuan, Xin, Zhili, Liu, Gang, Wang, Ying, Hansen, T. Matthew, Wang, Xiaojun, Wang, Rongqi, Zhang, Xiaolin, Frevert, Ernst U., Camp, Heidi S., Beutel, Bruce A., Sham, Hing L., Gu, Yu Gui

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Total synthesis of a biotinylated derivative of phorboxazole A via sonogashira coupling von Hansen, T.Matthew, Engler, Mary M., Forsyth, Craig J.

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