Nonribosomal biosynthesis of backbone-modified peptides von Niquille, David L., Hansen, Douglas A., Mori, Takahiro, Fercher, David, Kries, Hajo, Hilvert, Donald

Volltext

Evolution of a highly active and enantiospecific metalloenzyme from short peptides von Studer, Sabine, Hansen, Douglas A, Pianowski, Zbigniew L, Mittl, Peer R E, Debon, Aaron, Guffy, Sharon L, Der, Bryan S, Kuhlman, Brian, Hilvert, Donald

Volltext

Structural rearrangements of a polyketide synthase module during its catalytic cycle von Whicher, Jonathan R., Dutta, Somnath, Hansen, Douglas A., Hale, Wendi A., Chemler, Joseph A., Dosey, Annie M., Narayan, Alison R. H., Håkansson, Kristina, Sherman, David H., Smith, Janet L., Skiniotis, Georgios

Volltext

Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering von Koryakina, Irina, Kasey, Christian, McArthur, John B, Lowell, Andrew N, Chemler, Joseph A, Li, Shasha, Hansen, Douglas A, Sherman, David H, Williams, Gavin J

Volltext

Directing Group-Controlled Regioselectivity in an Enzymatic C–H Bond Oxygenation von Negretti, Solymar, Narayan, Alison R. H, Chiou, Karoline C, Kells, Petrea M, Stachowski, Jessica L, Hansen, Douglas A, Podust, Larissa M, Montgomery, John, Sherman, David H

Volltext

Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides von Almutairi, Mashal M., Park, Sung Ryeol, Rose, Simon, Hansen, Douglas A., Vázquez-Laslop, Nora, Douthwaite, Stephen, Sherman, David H., Mankin, Alexander S.

Volltext

Biocatalytic Synthesis of Pikromycin, Methymycin, Neomethymycin, Novamethymycin, and Ketomethymycin von Hansen, Douglas A, Rath, Christopher M, Eisman, Eli B, Narayan, Alison R. H, Kittendorf, Jeffrey D, Mortison, Jonathan D, Yoon, Yeo Joon, Sherman, David H

Volltext

Structure of a modular polyketide synthase von Dutta, Somnath, Whicher, Jonathan R., Hansen, Douglas A., Hale, Wendi A., Chemler, Joseph A., Congdon, Grady R., Narayan, Alison R. H., Håkansson, Kristina, Sherman, David H., Smith, Janet L., Skiniotis, Georgios

Volltext

High-throughput reprogramming of an NRPS condensation domain von Folger, Ines B., Frota, Natália F., Pistofidis, Angelos, Niquille, David L., Hansen, Douglas A., Schmeing, T. Martin, Hilvert, Donald

Volltext

Identification of a Thioesterase Bottleneck in the Pikromycin Pathway through Full-Module Processing of Unnatural Pentaketides von Hansen, Douglas A, Koch, Aaron A, Sherman, David H

Volltext

A Single Active Site Mutation in the Pikromycin Thioesterase Generates a More Effective Macrocyclization Catalyst von Koch, Aaron A, Hansen, Douglas A, Shende, Vikram V, Furan, Lawrence R, Houk, K. N, Jiménez-Osés, Gonzalo, Sherman, David H

Volltext

Probing Selectivity and Creating Structural Diversity Through Hybrid Polyketide Synthases von Koch, Aaron A., Schmidt, Jennifer J., Lowell, Andrew N., Hansen, Douglas A., Coburn, Katherine M., Chemler, Joseph A., Sherman, David H.

Volltext

Evolution of Efficient Modular Polyketide Synthases by Homologous Recombination von Chemler, Joseph A, Tripathi, Ashootosh, Hansen, Douglas A, O’Neil-Johnson, Mark, Williams, Russell B, Starks, Courtney, Park, Sung Ryeol, Sherman, David H

Volltext

Substrate Controlled Divergence in Polyketide Synthase Catalysis von Hansen, Douglas A, Koch, Aaron A, Sherman, David H

Volltext

Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins von Almutairi, Mashal M, Svetlov, Maxim S, Hansen, Douglas A, Khabibullina, Nelli F, Klepacki, Dorota, Kang, Han-Young, Sherman, David H, Vázquez-Laslop, Nora, Polikanov, Yury S, Mankin, Alexander S

Volltext

Cyanobacterial Polyketide Synthase Docking Domains: A Tool for Engineering Natural Product Biosynthesis von Whicher, Jonathan R., Smaga, Sarah S., Hansen, Douglas A., Brown, William C., Gerwick, William H., Sherman, David H., Smith, Janet L.

Volltext

Probing Selectivity and Creating Structural Diversity Through Hybrid Polyketide Synthases von Koch, Aaron A., Schmidt, Jennifer J., Lowell, Andrew N., Hansen, Douglas A., Coburn, Katherine M., Chemler, Joseph A., Sherman, David H.

Volltext

Evolution of a highly active and enantiospecific metalloenzyme from short peptides von Studer, Sabine, Hansen, Douglas A, Pianowski, Zbigniew L, Mittl, Peer R E, Debon, Aaron, Guffy, Sharon L, Der, Bryan S, Kuhlman, Brian, Hilvert, Donald

Volltext

Molecular Choreography Of An Antibiotic Assembly Line von Dutta, Somnath, Whicher, Jonathan R., Hansen, Douglas A., Hale, Wendi A., Chemler, Joseph A., Congdon, Grady R., Narayan, Alison R., Håkansson, Kristina, Sherman, David H., Smith, Janet L., Skiniotis, Georgios

Volltext

The Mussel Adhesive Protein (Mefp-1): A GREEN Corrosion Inhibitor von Zhang, Fan

Volltext bestellen