Structure and conserved function of iso-branched sphingoid bases from the nematode Caenorhabditis elegans von Hannich, J Thomas, Mellal, Denia, Feng, Suihan, Zumbuehl, Andreas, Riezman, Howard

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Patched regulates lipid homeostasis by controlling cellular cholesterol levels von Cadena del Castillo, Carla E., Hannich, J. Thomas, Kaech, Andres, Chiyoda, Hirohisa, Brewer, Jonathan, Fukuyama, Masamitsu, Færgeman, Nils J., Riezman, Howard, Spang, Anne

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Lysosome-targeted photoactivation reveals local sphingosine metabolism signatures von Feng, Suihan, Harayama, Takeshi, Chang, Dalu, Hannich, J Thomas, Winssinger, Nicolas, Riezman, Howard

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Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors von Dvorak, Vojtech, Casiraghi, Andrea, Colas, Claire, Koren, Anna, Tomek, Tatjana, Offensperger, Fabian, Rukavina, Andrea, Tin, Gary, Hahn, Elisa, Dobner, Sarah, Frommelt, Fabian, Boeszoermenyi, Andras, Bernada, Viktoriia, Hannich, J. Thomas, Ecker, Gerhard F., Winter, Georg E., Kubicek, Stefan, Superti-Furga, Giulio

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Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiae von Haribowo, A Galih, Hannich, J Thomas, Michel, Agnès H, Megyeri, Márton, Schuldiner, Maya, Kornmann, Benoît, Riezman, Howard

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Pharmacological perturbation of the phase-separating protein SMNDC1 von Enders, Lennart, Siklos, Marton, Borggräfe, Jan, Gaussmann, Stefan, Koren, Anna, Malik, Monika, Tomek, Tatjana, Schuster, Michael, Reiniš, Jiří, Hahn, Elisa, Rukavina, Andrea, Reicher, Andreas, Casteels, Tamara, Bock, Christoph, Winter, Georg E., Hannich, J. Thomas, Sattler, Michael, Kubicek, Stefan

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Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation von Kagiou, Chrysanthi, Cisneros, Jose A., Farnung, Jakob, Liwocha, Joanna, Offensperger, Fabian, Dong, Kevin, Yang, Ka, Tin, Gary, Horstmann, Christina S., Hinterndorfer, Matthias, Paulo, Joao A., Scholes, Natalie S., Sanchez Avila, Juan, Fellner, Michaela, Andersch, Florian, Hannich, J. Thomas, Zuber, Johannes, Kubicek, Stefan, Gygi, Steven P., Schulman, Brenda A., Winter, Georg E.

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Defining the SUMO-modified Proteome by Multiple Approaches in Saccharomyces cerevisiae von Hannich, J. Thomas, Lewis, Alaron, Kroetz, Mary B., Li, Shyr-Jiann, Heide, Heinrich, Emili, Andrew, Hochstrasser, Mark

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Top-Down Lipidomic Screens by Multivariate Analysis of High-Resolution Survey Mass Spectra von Schwudke, Dominik, Hannich, J. Thomas, Surendranath, Vineeth, Grimard, Vinciane, Moehring, Thomas, Burton, Lyle, Kurzchalia, Teymuras, Shevchenko, Andrej

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Lipid Profiling by Multiple Precursor and Neutral Loss Scanning Driven by the Data-Dependent Acquisition von Schwudke, Dominik, Oegema, Jeffrey, Burton, Lyle, Entchev, Eugeni, Hannich, J. Thomas, Ejsing, Christer S, Kurzchalia, Teymuras, Shevchenko, Andrej

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Heterogeneous modulation of Bcl-2 family members and drug efflux mediate MCL-1 inhibitor resistance in multiple myeloma von Bolomsky, Arnold, Miettinen, Juho J., Malyutina, Alina, Besse, Andrej, Huber, Julia, Fellinger, Stefanie, Breid, Helene, Parsons, Alun, Klavins, Kristaps, Hannich, J. Thomas, Kubicek, Stefan, Caers, Jo, Hübl, Wolfgang, Schreder, Martin, Zojer, Niklas, Driessen, Christoph, Tang, Jing, Besse, Lenka, Heckman, Caroline A., Ludwig, Heinz

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Metabolomic profiles differentiate between porto-sinusoidal vascular disorder, cirrhosis, and healthy individuals von Semmler, Georg, Petrenko, Oleksandr, Lozano, Juanjo Jose, Shalaby, Sarah, Sánchez-Avila, Juan I., Marella, Nara, Hannich, Thomas, Wöran, Katharina, Balcar, Lorenz, Simbrunner, Benedikt, Lampichler, Katharina, Mozayani, Behrang, Trauner, Michael, Mandorfer, Mattias, Reiberger, Thomas, García-Pagán, Juan-Carlos, Scheiner, Bernhard

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Distribution and functions of sterols and sphingolipids von Hannich, J Thomas, Umebayashi, Kyohei, Riezman, Howard

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Leptin increases hepatic triglyceride export via a vagal mechanism in humans von Metz, Matthäus, Beghini, Marianna, Wolf, Peter, Pfleger, Lorenz, Hackl, Martina, Bastian, Magdalena, Freudenthaler, Angelika, Harreiter, Jürgen, Zeyda, Maximilian, Baumgartner-Parzer, Sabina, Marculescu, Rodrig, Marella, Nara, Hannich, J. Thomas, Györi, Georg, Berlakovich, Gabriela, Roden, Michael, Krebs, Michael, Risti, Robert, Lõokene, Aivar, Trauner, Michael, Kautzky-Willer, Alexandra, Krššák, Martin, Stangl, Herbert, Fürnsinn, Clemens, Scherer, Thomas

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Methylation of the Sterol Nucleus by STRM-1 Regulates Dauer Larva Formation in Caenorhabditis elegans von Hannich, J. Thomas, Entchev, Eugeni V., Mende, Fanny, Boytchev, Hristio, Martin, René, Zagoriy, Vyacheslav, Theumer, Gabriele, Riezman, Isabelle, Riezman, Howard, Knölker, Hans-Joachim, Kurzchalia, Teymuras V.

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Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells von Offensperger, Fabian, Tin, Gary, Duran-Frigola, Miquel, Hahn, Elisa, Dobner, Sarah, Ende, Christopher W Am, Strohbach, Joseph W, Rukavina, Andrea, Brennsteiner, Vincenth, Ogilvie, Kevin, Marella, Nara, Kladnik, Katharina, Ciuffa, Rodolfo, Majmudar, Jaimeen D, Field, S Denise, Bensimon, Ariel, Ferrari, Luca, Ferrada, Evandro, Ng, Amanda, Zhang, Zhechun, Degliesposti, Gianluca, Boeszoermenyi, Andras, Martens, Sascha, Stanton, Robert, Müller, André C, Hannich, J Thomas, Hepworth, David, Superti-Furga, Giulio, Kubicek, Stefan, Schenone, Monica, Winter, Georg E

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Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP von Cigler, Marko, Imrichova, Hana, Frommelt, Fabian, Caramelle, Lucie, Depta, Laura, Rukavina, Andrea, Kagiou, Chrysanthi, Hannich, J Thomas, Mayor-Ruiz, Cristina, Superti-Furga, Giulio, Sievers, Sonja, Forrester, Alison, Laraia, Luca, Waldmann, Herbert, Winter, Georg E

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Combined Omics Approach Identifies Gambogic Acid and Related Xanthones as Covalent Inhibitors of the Serine Palmitoyltransferase Complex von Hoch, Dominic G., Abegg, Daniel, Hannich, J. Thomas, Pechalrieu, Dany, Shuster, Anton, Dwyer, Brendan G., Wang, Chao, Zhang, Xiaojin, You, Qidong, Riezman, Howard, Adibekian, Alexander

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Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling von Ng, Amanda, Offensperger, Fabian, Cisneros, Jose A., Scholes, Natalie S., Malik, Monika, Villanti, Ludovica, Rukavina, Andrea, Ferrada, Evandro, Hannich, J. Thomas, Koren, Anna, Kubicek, Stefan, Superti-Furga, Giulio, Winter, Georg E.

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Ceramide biosynthesis is critical for establishment of the intracellular niche of Toxoplasma gondii von Nyonda, Mary Akinyi, Kloehn, Joachim, Sosnowski, Piotr, Krishnan, Aarti, Lentini, Gaëlle, Maco, Bohumil, Marq, Jean-Baptiste, Hannich, J. Thomas, Hopfgartner, Gerard, Soldati-Favre, Dominique

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