Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia von Ancliff, Phil J., Blundell, Michael P., Cory, Giles O., Calle, Yolanda, Worth, Austen, Kempski, Helena, Burns, Siobhan, Jones, Gareth E., Sinclair, Jo, Kinnon, Christine, Hann, Ian M., Gale, Rosemary E., Linch, David C., Thrasher, Adrian J.

Volltext

Relationships between age at diagnosis, clinical features, and outcome of therapy in children treated in the Medical Research Council AML 10 and 12 trials for acute myeloid leukemi... von Webb, David K.H., Harrison, Georgina, Stevens, Richard F., Gibson, Brenda G., Hann, Ian M., Wheatley, Keith

Volltext

Predicting microbiologically defined infection in febrile neutropenic episodes in children: global individual participant data multivariable meta-analysis von Phillips, Robert S, Sung, Lillian, Amman, Roland A, Riley, Richard D, Castagnola, Elio, Haeusler, Gabrielle M, Klaassen, Robert, Tissing, Wim J E, Lehrnbecher, Thomas, Chisholm, Julia, Hakim, Hana, Ranasinghe, Neil, Paesmans, Marianne, Hann, Ian M, Stewart, Lesley A

Volltext

Paternal mosaicism proves the pathogenic nature of mutations in neutrophil elastase in severe congenital neutropenia von Ancliff, Phil J., Gale, Rosemary E., Watts, Michael J., Liesner, Ri, Hann, Ian M., Strobel, Stephan, Linch, David C.

Volltext

The value of allogeneic bone marrow transplant in patients with acute myeloid leukaemia at differing risk of relapse: results of the UK MRC AML 10 trial von Burnett, Alan K., Wheatley, Keith, Goldstone, Anthony H., Stevens, Richard F., Hann, Ian M., Rees, John H. K., Harrison, Georgina

Volltext

Predicting microbiologically defined infection in febrile neutropenic episodes in children: global individual participant data multivariable meta-analysis von Phillips, Robert S, Sung, Lillian, Ammann, Roland A, Riley, Richard D, Castagnola, Elio, Haeusler, Gabrielle M, Klaassen, Robert, Tissing, Wim Je, Lehrnbecher, Thomas, Chisholm, Julia, Hakim, Hana, Ranasinghe, Neil, Paesmans, Marianne, Hann, Ian M, Stewart, Lesley A

Volltext

Long‐term follow‐up of relapsed childhood acute lymphoblastic leukaemia von Chessells, Judith M., Veys, Paul, Kempski, Helena, Henley, Patricia, Leiper, Ali, Webb, David, Hann, Ian M.

Volltext

Three distinct subgroups of hypodiploidy in acute lymphoblastic leukaemia von Harrison, Christine J., Moorman, Anthony V., Broadfield, Zoë J., Cheung, Kan L., Harris, Rachel L., Reza Jalali, G., Robinson, Hazel M., Barber, Kerry E., Richards, Sue M., Mitchell, Christopher D., Eden, Tim O. B., Hann, Ian M., Hill, Frank G.H., Kinsey, Sally E., Gibson, Brenda E.S., Lilleyman, John, Vora, Ajay, Goldstone, Anthony H., Franklin, Ian M., Durrant, Jill, Martineau, Mary

Volltext

Randomised comparison of addition of autologous bone-marrow transplantation to intensive chemotherapy for acute myeloid leukaemia in first remission: results of MRC AML 10 trial von Burnett, Alan K, Goldstone, Anthony H, Stevens, Richard MF, Hann, Ian M, Rees, John KH, Gray, Richard G, Wheatley, Keith

Volltext

Treatment for myeloid leukaemia of Down syndrome: population‐based experience in the UK and results from the Medical Research Council AML 10 and AML 12 trials von Rao, Anupama, Hills, Robert K., Stiller, Charles, Gibson, Brenda E., Graaf, Siebold S.N., Hann, Ian M., O'Marcaigh, Aengus, Wheatley, Keith, Webb, David K.H.

Volltext

Outcome heterogeneity in childhood high-hyperdiploid acute lymphoblastic leukemia von Moorman, Anthony V., Richards, Sue M., Martineau, Mary, Cheung, Kan Luk, Robinson, Hazel M., Jalali, G. Reza, Broadfield, Zoë J., Harris, Rachel L., Taylor, Kerry E., Gibson, Brenda E.S., Hann, Ian M., Hill, Frank G.H., Kinsey, Sally E., Eden, Tim O.B., Mitchell, Christopher D., Harrison, Christine J.

Volltext

Paediatric myelodysplastic syndromes and juvenile myelomonocytic leukaemia in the UK: a population‐based study of incidence and survival von Passmore, S. Jane, Chessells, Judith M., Kempski, Helena, Hann, Ian M., Brownbill, Pat A., Stiller, Charles A.

Volltext

Marked improvements in outcome with chemotherapy alone in paediatric acute myeloid leukaemia: results of the United Kingdom Medical Research Council's 10th AML trial von Stevens, Richard F., Hann, Ian M., Wheatley, Keith, Gray, Richard G.

Volltext

Mutations in the ELA2 gene encoding neutrophil elastase are present in most patients with sporadic severe congenital neutropenia but only in some patients with the familial form of... von Ancliff, Phil J., Gale, Rosemary E., Liesner, Ri, Hann, Ian M., Linch, David C.

Volltext

Treatment‐related deaths during induction and first remission of acute myeloid leukaemia in children treated on the Tenth Medical Research Council Acute Myeloid Leukaemia Trial (MR... von Riley, Lynne C., Hann, Ian M., Wheatley, Keith, Stevens, R. F.

Volltext

Prospective gene expression analysis accurately subtypes acute leukaemia in children and establishes a commonality between hyperdiploidy and t(12;21) in acute lymphoblastic leukaem... von Delft, Frederik W., Bellotti, Tony, Luo, Zhiyuan, Jones, Louise K., Patel, Naina, Yiannikouris, Olga, Hill, Alex S., Hubank, Mike, Kempski, Helena, Fletcher, Danielle, Chaplin, Tracy, Foot, Nicola, Young, Bryan D., Hann, Ian M., Gammerman, Alex, Saha, Vaskar

Volltext

Results of treatment of children with refractory anaemia with excess blasts (RAEB) and RAEB in transformation (RAEBt) in Great Britain 1990–99 von Webb, David K. H., Passmore, Sarah J., Hann, Ian M., Harrison, Georgina, Wheatley, Keith, Chessells, Judith M.

Volltext

Oral ciprofloxacin plus colistin: prophylaxis against bacterial infection in neutropenic patients. A strategy for the prevention of emergence of antimicrobial resistance von Prentice, H. Grant, Hann, Ian M., Nazareth, Bernadette, Paterson, Pamela, Bhamra, Amrat, Kibbler, Christopher C.

Volltext

Intraocular relapse of childhood acute lymphoblastic leukaemia von Somervaille, Tim C. P., Hann, Ian M., Harrison, Georgina, Eden, Tim O.B., Gibson, Brenda E., Hill, Frank G., Mitchell, Chris, Kinsey, Sally E., Vora, Ajay J., Lilleyman, John S.

Volltext

Failure of a new protocol to improve treatment results in paediatric lymphoblastic leukaemia: lessons from the UK Medical Research Council trials UKALL X and UKALL XI von Chessells, Judith M., Harrison, Georgina, Richards, Susan M., Gibson, Brenda E., Bailey, Clifford C., Hill, Frank G. H., Hann, Ian M., On Childhood Leukaemia, Research Council Working Party

Volltext