PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis von Martin, Katherine, Pritchett, James, Llewellyn, Jessica, Mullan, Aoibheann F., Athwal, Varinder S., Dobie, Ross, Harvey, Emma, Zeef, Leo, Farrow, Stuart, Streuli, Charles, Henderson, Neil C., Friedman, Scott L., Hanley, Neil A., Piper Hanley, Karen

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Development of the Human Pancreas From Foregut to Endocrine Commitment von JENNINGS, Rachel E, BERRY, Andrew A, KIRKWOOD-WILSON, Rebecca, ROBERTS, Neil A, HEARN, Thomas, SALISBURY, Rachel J, BLAYLOCK, Jennifer, HANLEY, Karen Piper, HANLEY, Neil A

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Genetic Contribution to Non-alcoholic Fatty Liver Disease and Prognostic Implications von Martin, Katherine, Hatab, Anas, Athwal, Varinder S., Jokl, Elliot, Piper Hanley, Karen

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Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes von Baxter, Melissa, Withey, Sarah, Harrison, Sean, Segeritz, Charis-Patricia, Zhang, Fang, Atkinson-Dell, Rebecca, Rowe, Cliff, Gerrard, Dave T, Sison-Young, Rowena, Jenkins, Roz, Henry, Joanne, Berry, Andrew A, Mohamet, Lisa, Best, Marie, Fenwick, Stephen W, Malik, Hassan, Kitteringham, Neil R, Goldring, Chris E, Piper Hanley, Karen, Vallier, Ludovic, Hanley, Neil A

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An integrative transcriptomic atlas of organogenesis in human embryos von Gerrard, Dave T, Berry, Andrew A, Jennings, Rachel E, Piper Hanley, Karen, Bobola, Nicoletta, Hanley, Neil A

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SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis von Athwal, Varinder S., Pritchett, James, Martin, Katherine, Llewellyn, Jessica, Scott, Jennifer, Harvey, Emma, Zaitoun, Abed M., Mullan, Aoibheann F., Zeef, Leo A. H., Friedman, Scott L., Irving, William L., Hanley, Neil A., Guha, Indra N., Piper Hanley, Karen

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PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis von Jokl, Elliot, Mullan, Aoibheann F., Simpson, Kara, Birchall, Lindsay, Pearmain, Laurence, Martin, Katherine, Pritchett, James, Raza, Sayyid, Shah, Rajesh, Hodson, Nigel W., Williams, Craig J., Camacho, Elizabeth, Zeef, Leo, Donaldson, Ian, Athwal, Varinder S., Hanley, Neil A., Piper Hanley, Karen

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Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord-specific markers during early human intervertebral disc developmen... von Rodrigues-Pinto, Ricardo, Berry, Andrew, Piper-Hanley, Karen, Hanley, Neil, Richardson, Stephen M., Hoyland, Judith A.

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SOX9 is required for kidney fibrosis and activates NAV3 to drive renal myofibroblast function von Raza, Sayyid, Jokl, Elliot, Pritchett, James, Martin, Katherine, Su, Kim, Simpson, Kara, Birchall, Lindsay, Mullan, Aoibheann F., Athwal, Varinder S., Doherty, Daniel T., Zeef, Leo, Henderson, Neil C., Kalra, Philip A., Hanley, Neil A., Hanley, Karen Piper

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In humans, early cortisol biosynthesis provides a mechanism to safeguard female sexual development von Goto, Masahiro, Piper Hanley, Karen, Marcos, Josep, Wood, Peter J, Wright, Sarah, Postle, Anthony D, Cameron, Iain T, Mason, J Ian, Wilson, David I, Hanley, Neil A

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Bioluminescence in Dinoflagellates: Evidence that the Adaptive Value of Bioluminescence in Dinoflagellates is Concentration Dependent von Hanley, Karen A., Widder, Edith A.

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P2 PDLIM5 in hepatic stellate cells is upstream of pro-fibrotic YAP1 mechano-transduction von Abdelmottaleb, Dina, Hanley, Karen Piper, Pritchett, James

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SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis von Athwal, Varinder S, Pritchett, James, Llewellyn, Jessica, Martin, Katherine, Camacho, Elizabeth, Raza, Sayyid MA, Phythian‐Adams, Alexander, Birchall, Lindsay J, Mullan, Aoibheann F, Su, Kim, Pearmain, Laurence, Dolman, Grace, Zaitoun, Abed M, Friedman, Scott L, MacDonald, Andrew, Irving, William L, Guha, Indra N, Hanley, Neil A, Piper Hanley, Karen

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Laser Capture and Deep Sequencing Reveals the Transcriptomic Programmes Regulating the Onset of Pancreas and Liver Differentiation in Human Embryos von Jennings, Rachel E., Berry, Andrew A., Gerrard, David T., Wearne, Stephen J., Strutt, James, Withey, Sarah, Chhatriwala, Mariya, Piper Hanley, Karen, Vallier, Ludovic, Bobola, Nicoletta, Hanley, Neil A.

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Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans von Pritchett, James, Harvey, Emma, Athwal, Varinder, Berry, Andrew, Rowe, Cliff, Oakley, Fiona, Moles, Anna, Mann, Derek A., Bobola, Nicoletta, Sharrocks, Andrew D., Thomson, Brian J., Zaitoun, Abed M., Irving, William L., Guha, Indra N., Hanley, Neil A., Hanley, Karen Piper

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Improving detection of cystic fibrosis related liver disease using liver fibrosis assessment tools von Scott, Jennifer A., Jones, Andrew M., Jokl, Elliot, Gordon-Walker, Timothy, Barry, Peter J., Hanley, Neil A., Piper Hanley, Karen, Athwal, Varinder S.

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Review article: epidemiology, pathogenesis and management of liver disease in adults with cystic fibrosis von Scott, Jennifer, Jones, Andrew M., Piper Hanley, Karen, Athwal, Varinder S.

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Unlocking the post-transplant microenvironment for successful islet function and survival von Doherty, Daniel T., Khambalia, Hussein A., van Dellen, David, Jennings, Rachel E., Piper Hanley, Karen

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Ectopic SOX9 Mediates Extracellular Matrix Deposition Characteristic of Organ Fibrosis von Piper Hanley, Karen, Oakley, Fiona, Sugden, Sarah, Wilson, David I., Mann, Derek A., Hanley, Neil A.

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Epimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells von Pritchett, James, Athwal, Varinder S, Harvey, Emma, Martin, Katherine, Llewellyn, Jessica, Ireland, Philip, Nicolaides, Alexander, Humphries, Martin J, Bobola, Nicoletta, Hanley, Neil A, Piper Hanley, Karen

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