The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy von Gomez-Suaga, Patricia, Paillusson, Sebastien, Stoica, Radu, Noble, Wendy, Hanger, Diane P., Miller, Christopher C.J.

Volltext

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease von Hanger, Diane P, Anderton, Brian H, Noble, Wendy

Volltext

Physiological release of endogenous tau is stimulated by neuronal activity von Pooler, Amy M, Phillips, Emma C, Lau, Dawn H W, Noble, Wendy, Hanger, Diane P

Volltext

A role for tau at the synapse in Alzheimer's disease pathogenesis von Pooler, Amy M., Noble, Wendy, Hanger, Diane P.

Volltext

The importance of tau phosphorylation for neurodegenerative diseases von Noble, Wendy, Hanger, Diane P, Miller, Christopher C J, Lovestone, Simon

Volltext

Roles of tau protein in health and disease von Guo, Tong, Noble, Wendy, Hanger, Diane P.

Volltext

Tau phosphorylation affects its axonal transport and degradation von Rodríguez-Martín, Teresa, Cuchillo-Ibáñez, Inmaculada, Noble, Wendy, Nyenya, Fanon, Anderton, Brian H, Hanger, Diane P

Volltext

Inhibition of glycogen synthase kinase-3 by BTA-EG4 reduces tau abnormalities in an organotypic brain slice culture model of Alzheimer’s disease von Croft, Cara L., Kurbatskaya, Ksenia, Hanger, Diane P., Noble, Wendy

Volltext

Novel Phosphorylation Sites in Tau from Alzheimer Brain Support a Role for Casein Kinase 1 in Disease Pathogenesis von Hanger, Diane P., Byers, Helen L., Wray, Selina, Leung, Kit-Yi, Saxton, Malcolm J., Seereeram, Anjan, Reynolds, C. Hugh, Ward, Malcolm A., Anderton, Brian H.

Volltext

Functional Implications of Glycogen Synthase Kinase-3-Mediated Tau Phosphorylation von Hanger, Diane P., Noble, Wendy

Volltext

Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons von Rodríguez-Martín, Teresa, Pooler, Amy M, Lau, Dawn H.W, Mórotz, Gábor M, De Vos, Kurt J, Gilley, Jonathan, Coleman, Michael P, Hanger, Diane P

Volltext

Editorial: Tau Propagation Mechanisms: Cell Models, Animal Models, and Beyond von Motoi, Yumiko, Hanger, Diane P., Hasegawa, Masato

Volltext

Age-dependent axonal transport and locomotor changes and tau hypophosphorylation in a “P301L” tau knockin mouse von Gilley, Jonathan, Seereeram, Anjan, Ando, Kunie, Mosely, Suzanne, Andrews, Simon, Kerschensteiner, Martin, Misgeld, Thomas, Brion, Jean-Pierre, Anderton, Brian, Hanger, Diane P, Coleman, Michael P

Volltext

Trimming away tau in neurodegeneration von Noble, Wendy, Hanger, Diane P

Volltext

Mediators of tau phosphorylation in the pathogenesis of Alzheimer's disease von Hanger, Diane P, Seereeram, Anjan, Noble, Wendy

Volltext

Direct analysis of tau from PSP brain identifies new phosphorylation sites and a major fragment of N-terminally cleaved tau containing four microtubule-binding repeats von Wray, Selina, Saxton, Malcolm, Anderton, Brian H, Hanger, Diane P

Volltext

A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies von Giacomini, Caterina, Koo, Chuay-Yeng, Yankova, Natalia, Tavares, Ignatius A, Wray, Selina, Noble, Wendy, Hanger, Diane P, Morris, Jonathan D H

Volltext

A pathogenic tau fragment compromises microtubules, disrupts insulin signaling and induces the unfolded protein response von Guo, Tong, Dakkak, Dina, Rodriguez-Martin, Teresa, Noble, Wendy, Hanger, Diane P

Volltext

α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production von Paillusson, Sébastien, Gomez-Suaga, Patricia, Stoica, Radu, Little, Daniel, Gissen, Paul, Devine, Michael J., Noble, Wendy, Hanger, Diane P., Miller, Christopher C. J.

Volltext

Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice von Gilley, Jonathan, Ando, Kunie, Seereeram, Anjan, Rodríguez-Martín, Teresa, Pooler, Amy M, Sturdee, Laura, Anderton, Brian H, Brion, Jean-Pierre, Hanger, Diane P, Coleman, Michael P

Volltext