Reprogramming the antigen specificity of B cells using genome-editing technologies von Voss, James E, Gonzalez-Martin, Alicia, Andrabi, Raiees, Fuller, Roberta P, Murrell, Ben, McCoy, Laura E, Porter, Katelyn, Huang, Deli, Li, Wenjuan, Sok, Devin, Le, Khoa, Briney, Bryan, Chateau, Morgan, Rogers, Geoffrey, Hangartner, Lars, Feeney, Ann J, Nemazee, David, Cannon, Paula, Burton, Dennis R

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Points: Reducing juniors' hours of work von Hangartner, D R W, Braithwaite, J E G

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Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs von Hoot, Sam, McGuire, Andrew T, Cohen, Kristen W, Strong, Roland K, Hangartner, Lars, Klein, Florian, Diskin, Ron, Scheid, Johannes F, Sather, D Noah, Burton, Dennis R, Stamatatos, Leonidas

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Reducing Juniors' Hours Of Work von Hangartner, D. R. W., Braithwaite, J. E. G.

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Validity of Charlson Comorbidity Index in patients hospitalised with acute coronary syndrome. Insights from the nationwide AMIS Plus registry 2002–2012 von Radovanovic, Dragana, Seifert, Burkhardt, Urban, Philip, Eberli, Franz R, Rickli, Hans, Bertel, Osmund, Puhan, Milo A, Erne, Paul

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Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge von Grunst, Michael W, Gil, Hwi Min, Grandea, 3rd, Andres G, Snow, Brian J, Andrabi, Raiees, Nedellec, Rebecca, Burton, Iszac, Clark, Natasha M, Janaka, Sanath Kumar, Keles, Nida K, Moriarty, Ryan V, Weiler, Andrea M, Capuano, 3rd, Saverio, Fennessey, Christine M, Friedrich, Thomas C, O'Connor, Shelby L, O'Connor, David H, Broman, Aimee T, Keele, Brandon F, Lifson, Jeffrey D, Hangartner, Lars, Burton, Dennis R, Evans, David T

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Twenty-Year Trends in the Incidence and Outcome of Cardiogenic Shock in AMIS Plus Registry von Hunziker, Lukas, Radovanovic, Dragana, Jeger, Raban, Pedrazzini, Giovanni, Cuculi, Florim, Urban, Philip, Erne, Paul, Rickli, Hans, Pilgrim, Thomas, Hess, F, Simon, R, Hangartner, P.J, Hufschmid, U, Hornig, B, Altwegg, L, Trummler, S, Windecker, S, Rueff, T, Loretan, P, Roethlisberger, C, Evéquoz, D, Mang, G, Ryser, D, Müller, P, Jecker, R, Kistler, W, Hongler, T, Stäuble, S, Freiwald, G, Schmid, H.P, Stauffer, J.C, Cook, S, Bietenhard, K, Roffi, M, Wojtyna, W, Schönenberger, R, Simonin, C, Waldburger, R, Schmidli, M, Federspiel, B, Weiss, E.M, Marty, H, Weber, K, Zender, H, Poepping, I, Hugi, A, Koltai, E, Iglesias, J.F, Erne, P, Heimes, T, Jordan, B, Pagnamenta, A, Feraud, P, Beretta, E, Stettler, C, Repond, F, Widmer, F, Heimgartner, C, Polikar, R, Bassetti, S, Iselin, H.U, Giger, M, Egger, P, Kaeslin, T, Fischer, A, Herren, T, Eichhorn, P, Neumeier, C, Flury, G, Girod, G, Vogel, R, Niggli, B, Yoon, S, Nossen, J, Stoller, U, Veragut, U.P, Bächli, E, Weber, A, Schmidt, D, Hellermann, J, Eriksson, U, Fischer, T, Peter, M, Gasser, S, Fatio, R, Vogt, M, Ramsay, D, Wyss, C, Bertel, O, Maggiorini, M, Eberli, F, Christen, S

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Temporal trends in the treatment and outcomes of elderly patients with acute coronary syndrome von Schoenenberger, Andreas W, Radovanovic, Dragana, Windecker, Stephan, Iglesias, Juan F, Pedrazzini, Giovanni, Stuck, Andreas E, Erne, Paul

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Twenty-year trends in the prevalence of modifiable cardiovascular risk factors in young acute coronary syndrome patients hospitalized in Switzerland von Mahendiran, Thabo, Hoepli, André, Foster-Witassek, Fabienne, Rickli, Hans, Roffi, Marco, Eberli, Franz, Pedrazzini, Giovanni, Jeger, Raban, Radovanovic, Dragana, Fournier, Stephane

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Acute coronary syndromes in young patients: Presentation, treatment and outcome von Schoenenberger, Andreas W, Radovanovic, Dragana, Stauffer, Jean-Christophe, Windecker, Stephan, Urban, Philip, Niedermaier, Gregor, Keller, Pierre-Frédéric, Gutzwiller, Felix, Erne, Paul

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Best practice data life cycle approaches for the life sciences [version 2; peer review: 2 approved] von Griffin, Philippa C, Khadake, Jyoti, LeMay, Kate S, Lewis, Suzanna E, Orchard, Sandra, Pask, Andrew, Pope, Bernard, Roessner, Ute, Russell, Keith, Seemann, Torsten, Treloar, Andrew, Tyagi, Sonika, Christiansen, Jeffrey H, Dayalan, Saravanan, Gladman, Simon, Hangartner, Sandra B, Hayden, Helen L, Ho, William W.H, Keeble-Gagnère, Gabriel, Korhonen, Pasi K, Neish, Peter, Prestes, Priscilla R, Richardson, Mark F, Watson-Haigh, Nathan S, Wyres, Kelly L, Young, Neil D, Schneider, Maria Victoria

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Correction: Recombinant HIV Envelope Proteins Fail to Engage Germline Versions of Anti-CD4bs bNAbs von Hoot, Sam, McGuire, Andrew T., Cohen, Kristen W., Strong, Roland K., Hangartner, Lars, Klein, Florian, Diskin, Ron, Scheid, Johannes F., Sather, D. Noah, Burton, Dennis R., Stamatatos, Leonidas

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Outcome of patients admitted with acute coronary syndrome on palliative treatment: insights from the nationwide AMIS Plus Registry 1997–2014 von Erne, Paul, Radovanovic, Dragana, Seifert, Burkhardt, Bertel, Osmund, Urban, Philip

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Engineered mice and B cell lines expressing broadly neutralizing antibodies and their unmutated precursors: tools for HIV vaccinology von Nemazee, D, Doyle-Cooper, C, Ota, T, Cooper, AB, Huber, M, Falkowska, E, Doores, K, Hangartner, L, Le, K, Sok, D, Jardine, J, Lifson, J, Wu, X, Mascola, JR, Poignard, P, Binley, JM, Chakrabarti, BK, Schief, WR, Wyatt, RT, Burton, DR

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Inpatient versus outpatient onsets of acute myocardial infarction von Erne, Paul, Bertel, Osmund, Urban, Philip, Pedrazzini, Giovanni, Lüscher, Thomas F, Radovanovic, Dragana

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Best practice data life cycle approaches for the life sciences [version 1; peer review: 2 approved with reservations] von Griffin, Philippa C, Khadake, Jyoti, LeMay, Kate S, Lewis, Suzanna E, Orchard, Sandra, Pask, Andrew, Pope, Bernard, Roessner, Ute, Russell, Keith, Seemann, Torsten, Treloar, Andrew, Tyagi, Sonika, Christiansen, Jeffrey H, Dayalan, Saravanan, Gladman, Simon, Hangartner, Sandra B, Hayden, Helen L, Ho, William W.H, Keeble-Gagnère, Gabriel, Korhonen, Pasi K, Neish, Peter, Prestes, Priscilla R, Richardson, Mark F, Watson-Haigh, Nathan S, Wyres, Kelly L, Young, Neil D, Schneider, Maria Victoria

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Recombinant HIV Envelope Proteins Fail to Engage Germline Versions of Anti-CD4bs bNAbs von Hoot, Sam, McGuire, Andrew T, Cohen, Kristen W, Strong, Roland K, Hangartner, Lars, Klein, Florian, Diskin, Ron, Scheid, Johannes F, Sather, D Noah, Burton, Dennis R, Stamatatos, Leonidas

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Impact of Changing Definitions for Myocardial Infarction: A Report from the AMIS Registry von Urban, Philip, MD, Radovanovic, Dragana, MD, Erne, Paul, MD, Stauffer, Jean-Christophe, MD, Pedrazzini, Giovanni, MD, Windecker, Stephan, MD, Bertel, Osmund, MD

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Outcome of patients with acute coronary syndrome in hospitals of different sizes. A report from the AMIS Plus Registry von Radovanovic, Dragana, Urban, Philip, Simon, René, Schmidli, Markus, Maggiorini, Marco, Rickli, Hans, Stauffer, Jean-Christophe, Seifert, Burkhardt, Gutzwiller, Felix, Erne, Paul

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Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques von Hessell, A J, Poignard, P, Hunter, M, Hangartner, L, Tehrani, D M, Bleeker, W K, Parren, P W H I, Marx, P A, Burton, D R

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