Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung von Lafkas, Daniel, Shelton, Amy, Chiu, Cecilia, de Leon Boenig, Gladys, Chen, Yongmei, Stawicki, Scott S., Siltanen, Christian, Reichelt, Mike, Zhou, Meijuan, Wu, Xiumin, Eastham-Anderson, Jeffrey, Moore, Heather, Roose-Girma, Meron, Chinn, Yvonne, Hang, Julie Q., Warming, Søren, Egen, Jackson, Lee, Wyne P., Austin, Cary, Wu, Yan, Payandeh, Jian, Lowe, John B., Siebel, Christian W.

Volltext

An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma von Maun, Henry R., Jackman, Janet K., Choy, David F., Loyet, Kelly M., Staton, Tracy L., Jia, Guiquan, Dressen, Amy, Hackney, Jason A., Bremer, Meire, Walters, Benjamin T., Vij, Rajesh, Chen, Xiaocheng, Trivedi, Neil N., Morando, Ashley, Lipari, Michael T., Franke, Yvonne, Wu, Xiumin, Zhang, Juan, Liu, John, Wu, Ping, Chang, Diana, Orozco, Luz D., Christensen, Erin, Wong, Manda, Corpuz, Racquel, Hang, Julie Q., Lutman, Jeff, Sukumaran, Siddharth, Wu, Yan, Ubhayakar, Savita, Liang, Xiaorong, Schwartz, Lawrence B., Babina, Magda, Woodruff, Prescott G., Fahy, John V., Ahuja, Rahul, Caughey, George H., Kusi, Aija, Dennis, Mark S., Eigenbrot, Charles, Kirchhofer, Daniel, Austin, Cary D., Wu, Lawren C., Koerber, James T., Lee, Wyne P., Yaspan, Brian L., Alatsis, Kathila R., Arron, Joseph R., Lazarus, Robert A., Yi, Tangsheng

Volltext

Substrate-dependent inhibition or stimulation of HIV RNase H activity by non-nucleoside reverse transcriptase inhibitors (NNRTIs) von Hang, Julie Q., Li, Yu, Yang, Yanli, Cammack, Nick, Mirzadegan, Tara, Klumpp, Klaus

Volltext

Cyclic amide bioisosterism: Strategic application to the design and synthesis of HCV NS5B polymerase inhibitors von Yang, Hanbiao, Hendricks, Robert T., Arora, Nidhi, Nitzan, Dov, Yee, Calvin, Lucas, Matthew C., Yang, Yanli, Fung, Amy, Rajyaguru, Sonal, Harris, Seth F., Leveque, Vincent J.P., Hang, Julie Q., Pogam, Sophie Le, Reuter, Deborah, Tavares, Gisele A.

Volltext

Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members von Yang, Yanli, Yeh, Sherry H, Madireddi, Shravan, Matochko, Wadim L, Gu, Chen, Pacheco Sanchez, Patricia, Ultsch, Mark, De Leon Boenig, Gladys, Harris, Seth F, Leonard, Brandon, Scales, Suzie J, Zhu, Jing W, Christensen, Erin, Hang, Julie Q, Brezski, Randall J, Marsters, Scot, Ashkenazi, Avi, Sukumaran, Siddharth, Chiu, Henry, Cubas, Rafael, Kim, Jeong M, Lazar, Greg A

Volltext

Discovery of triazolinone non-nucleoside inhibitors of HIV reverse transcriptase von Sweeney, Zachary K., Acharya, Sahaja, Briggs, Andrew, Dunn, James P., Elworthy, Todd R., Fretland, Jennifer, Giannetti, Anthony M., Heilek, Gabrielle, Li, Yu, Kaiser, Ann C., Martin, Michael, Saito, Y. David, Smith, Mark, Suh, Judy M., Swallow, Steven, Wu, Jeffrey, Hang, Julie Q., Zhou, Amy S., Klumpp, Klaus

Volltext

An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma von Maun, Henry R., Jackman, Janet K., Choy, David F., Loyet, Kelly M., Staton, Tracy L., Jia, Guiquan, Dressen, Amy, Hackney, Jason A., Bremer, Meire, Walters, Benjamin T., Vij, Rajesh, Chen, Xiaocheng, Trivedi, Neil N., Morando, Ashley, Lipari, Michael T., Franke, Yvonne, Wu, Xiumin, Zhang, Juan, Liu, John, Wu, Ping, Chang, Diana, Orozco, Luz D., Christensen, Erin, Wong, Manda, Corpuz, Racquel, Hang, Julie Q., Lutman, Jeff, Sukumaran, Siddharth, Wu, Yan, Ubhayakar, Savita, Liang, Xiaorong, Schwartz, Lawrence B., Babina, Magda, Woodruff, Prescott G., Fahy, John V., Ahuja, Rahul, Caughey, George H., Kusi, Aija, Dennis, Mark S., Eigenbrot, Charles, Kirchhofer, Daniel, Austin, Cary D., Wu, Lawren C., Koerber, James T., Lee, Wyne P., Yaspan, Brian L., Alatsis, Kathila R., Arron, Joseph R., Lazarus, Robert A., Yi, Tangsheng

Volltext

Diphenyl Ether Non-Nucleoside Reverse Transcriptase Inhibitors with Excellent Potency Against Resistant Mutant Viruses and Promising Pharmacokinetic Properties von Sweeney, Zachary K., Kennedy-Smith, Joshua J., Wu, Jeffrey, Arora, Nidhi, Billedeau, J. Roland, Davidson, James P., Fretland, Jennifer, Hang, Julie Q., Heilek, Gabrielle M., Harris, Seth F., Hirschfeld, Donald, Inbar, Petra, Javanbakht, Hassan, Jernelius, Jesper A., Jin, Qingwu, Li, Yu, Liang, Weiling, Roetz, Ralf, Sarma, Keshab, Smith, Mark, Stefanidis, Dimitrio, Su, Guoping, Suh, Judy M., Villaseñor, Armando G., Welch, Michael, Zhang, Fang-Jie, Klumpp, Klaus

Volltext

Design of Annulated Pyrazoles as Inhibitors of HIV-1 Reverse Transcriptase von Sweeney, Zachary K, Harris, Seth F, Arora, Nidhi, Javanbakht, Hassan, Li, Yu, Fretland, Jennifer, Davidson, James P, Billedeau, J. Roland, Gleason, Shelley K, Hirschfeld, Donald, Kennedy-Smith, Joshua J, Mirzadegan, Taraneh, Roetz, Ralf, Smith, Mark, Sperry, Sarah, Suh, Judy M, Wu, Jeffrey, Tsing, Stan, Villaseñor, Armando G, Paul, Amber, Su, Guoping, Heilek, Gabrielle, Hang, Julie Q, Zhou, Amy S, Jernelius, Jesper A, Zhang, Fang-Jie, Klumpp, Klaus

Volltext

Synthesis and biological activity of new pyridone diaryl ether non-nucleoside inhibitors of HIV-1 reverse transcriptase von Kennedy-Smith, Joshua J., Arora, Nidhi, Billedeau, J. Roland, Fretland, Jennifer, Hang, Julie Q., Heilek, Gabrielle M., Harris, Seth F., Hirschfeld, Donald, Javanbakht, Hassan, Li, Yu, Liang, Weiling, Roetz, Ralf, Smith, Mark, Su, Guoping, Suh, Judy M., Villaseñor, Armando G., Wu, Jeffrey, Yasuda, Dennis, Klumpp, Klaus, Sweeney, Zachary K.

Volltext

Characterization of the 16S rRNA- and membrane-binding domains of Streptococcus pneumoniae Era GTPase: structural and functional implications von Hang, Julie Q, Zhao, Genshi

Volltext

Characterization of the 16S rRNA‐ and membrane‐binding domains of Streptococcus pneumoniae Era GTPase von Hang, Julie Q., Zhao, Genshi

Volltext

Silibinin (Legalon-SIL) Inhibits HCV Replication In Vitro von Najera, Isabel, Leveque, Vincent, McCown, Matt, Hang, Julie Q., Ma, Han, Rajyaguru, Sonal, Fung, Amy, Yang, Yanli, Liu, Yang, Kular, Simran, Cammack, Nick, Ferenci, Peter, Klumpp, Klaus

Volltext

2′-Deoxy-nucleoside Analogs can be Potent Dual Inhibitors of HCV and HIV Replication with Selectivity against Human Polymerases von Klumpp, Klaus, Su, Guoping, Leveque, Vincent, Deval, Jerome, Heilek, Gabrielle, Rajyaguru, Sonal, Li, Yu, Hang, Julie Q., Ma, Han, Inocencio, Nicole, Kalayanov, Genadiy, Winqvist, Anna, Smith, David B., Cammack, Nick, Johansson, Nils Gunnar, Najera, Isabel

Volltext

Anti-Jagged2 antibodies and methods of use von Wu, Yan, Chinn, Yvonne, Siebel, Christian W, Lafkas, Daniel, Hang, Julie Q

Volltext bestellen

Diphenyl Ether Non-Nucleoside Reverse Transcriptase Inhibitors with Excellent Potency Against Resistant Mutant Viruses and Promising Pharmacokinetic Properties (ChemMedChem 1/2009) von Sweeney, Zachary K, Kennedy-Smith, Joshua J, Wu, Jeffrey, Arora, Nidhi, Billedeau, J Roland, Davidson, James P, Fretland, Jennifer, Hang, Julie Q, Heilek, Gabrielle M, Harris, Seth F, Hirschfeld, Donald, Inbar, Petra, Javanbakht, Hassan, Jernelius, Jesper A, Jin, Qingwu, Li, Yu, Liang, Weiling, Roetz, Ralf, Sarma, Keshab, Smith, Mark, Stefanidis, Dimitrio, Su, Guoping, Suh, Judy M, Villasenor, Armando G, Welch, Michael, Zhang, Fang-Jie, Klumpp, Klaus

Volltext

Synthesis and biological activity of new pyridone diaryl ether non-nucleoside inhibitors of HIV-1 reverse transcriptaseElectronic supplementary information (ESI) available: Crystal... von Kennedy-Smith, Joshua J, Arora, Nidhi, Billedeau, J. Roland, Fretland, Jennifer, Hang, Julie Q, Heilek, Gabrielle M, Harris, Seth F, Hirschfeld, Donald, Javanbakht, Hassan, Li, Yu, Liang, Weiling, Roetz, Ralf, Smith, Mark, Su, Guoping, Suh, Judy M, Villaseñor, Armando G, Wu, Jeffrey, Yasuda, Dennis, Klumpp, Klaus, Sweeney, Zachary K

Volltext

TIE2-BINDING AGENTS AND METHODS OF USE von Sanowar, Sarah, Shivva, Vittal, DiCara, Danielle Marie, Agard, Nicholas John, Hang, Julie Q, Yan, Minhong, Zhang, Gu, Morse, Robert Paul, Hass, Philip E, Christensen, Erin L

Volltext bestellen

Cover Picture: Diphenyl Ether Non-Nucleoside Reverse Transcriptase Inhibitors with Excellent Potency Against Resistant Mutant Viruses and Promising Pharmacokinetic Properties (Chem... von Sweeney, Zachary K., Kennedy-Smith, Joshua J., Wu, Jeffrey, Arora, Nidhi, Billedeau, J. Roland, Davidson, James P., Fretland, Jennifer, Hang, Julie Q., Heilek, Gabrielle M., Harris, Seth F., Hirschfeld, Donald, Inbar, Petra, Javanbakht, Hassan, Jernelius, Jesper A., Jin, Qingwu, Li, Yu, Liang, Weiling, Roetz, Ralf, Sarma, Keshab, Smith, Mark, Stefanidis, Dimitrio, Su, Guoping, Suh, Judy M., Villaseñor, Armando G., Welch, Michael, Zhang, Fang-Jie, Klumpp, Klaus

Volltext

Tie2-binding agents and methods of use von Sanowar, Sarah, Shivva, Vittal, Dicara, Danielle Marie, Agard, Nicholas John, Hang, Julie Q, Yan, Minhong, Zhang, Gu, Morse, Robert Paul, Hass, Philip E, Christensen, Erin L

Volltext bestellen