The role of glia in protein aggregation von Li, Qingyun, Haney, Michael S.

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Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain von Marschallinger, Julia, Iram, Tal, Zardeneta, Macy, Lee, Song E., Lehallier, Benoit, Haney, Michael S., Pluvinage, John V., Mathur, Vidhu, Hahn, Oliver, Morgens, David W., Kim, Justin, Tevini, Julia, Felder, Thomas K., Wolinski, Heimo, Bertozzi, Carolyn R., Bassik, Michael C., Aigner, Ludwig, Wyss-Coray, Tony

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Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens von Morgens, David W., Wainberg, Michael, Boyle, Evan A., Ursu, Oana, Araya, Carlos L., Tsui, C. Kimberly, Haney, Michael S., Hess, Gaelen T., Han, Kyuho, Jeng, Edwin E., Li, Amy, Snyder, Michael P., Greenleaf, William J., Kundaje, Anshul, Bassik, Michael C.

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CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity von Kramer, Nicholas J., Haney, Michael S., Morgens, David W., Jovičić, Ana, Couthouis, Julien, Li, Amy, Ousey, James, Ma, Rosanna, Bieri, Gregor, Tsui, C. Kimberly, Shi, Yingxiao, Hertz, Nicholas T., Tessier-Lavigne, Marc, Ichida, Justin K., Bassik, Michael C., Gitler, Aaron D.

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CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation von Cheng, Weiwei, Wang, Shaopeng, Zhang, Zhe, Morgens, David W., Hayes, Lindsey R., Lee, Soojin, Portz, Bede, Xie, Yongzhi, Nguyen, Baotram V., Haney, Michael S., Yan, Shirui, Dong, Daoyuan, Coyne, Alyssa N., Yang, Junhua, Xian, Fengfan, Cleveland, Don W., Qiu, Zhaozhu, Rothstein, Jeffrey D., Shorter, James, Gao, Fen-Biao, Bassik, Michael C., Sun, Shuying

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APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia von Haney, Michael S., Pálovics, Róbert, Munson, Christy Nicole, Long, Chris, Johansson, Patrik K., Yip, Oscar, Dong, Wentao, Rawat, Eshaan, West, Elizabeth, Schlachetzki, Johannes C. M., Tsai, Andy, Guldner, Ian Hunter, Lamichhane, Bhawika S., Smith, Amanda, Schaum, Nicholas, Calcuttawala, Kruti, Shin, Andrew, Wang, Yung-Hua, Wang, Chengzhong, Koutsodendris, Nicole, Serrano, Geidy E., Beach, Thomas G., Reiman, Eric M., Glass, Christopher K., Abu-Remaileh, Monther, Enejder, Annika, Huang, Yadong, Wyss-Coray, Tony

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Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens von Haney, Michael S., Bohlen, Christopher J., Morgens, David W., Ousey, James A., Barkal, Amira A., Tsui, C. Kimberly, Ego, Braeden K., Levin, Roni, Kamber, Roarke A., Collins, Hannah, Tucker, Andrew, Li, Amy, Vorselen, Daan, Labitigan, Lorenzo, Crane, Emily, Boyle, Evan, Jiang, Lihua, Chan, Joanne, Rincón, Esther, Greenleaf, William J., Li, Billy, Snyder, Michael P., Weissman, Irving L., Theriot, Julie A., Collins, Sean R., Barres, Ben A., Bassik, Michael C.

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Astrocyte‐to‐astrocyte contact and a positive feedback loop of growth factor signaling regulate astrocyte maturation von Li, Jiwen, Khankan, Rana R., Caneda, Christine, Godoy, Marlesa I., Haney, Michael S., Krawczyk, Mitchell C., Bassik, Michael C., Sloan, Steven A., Zhang, Ye

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Local and global chromatin interactions are altered by large genomic deletions associated with human brain development von Zhang, Xianglong, Zhang, Ying, Zhu, Xiaowei, Purmann, Carolin, Haney, Michael S., Ward, Thomas, Khechaduri, Arineh, Yao, Jie, Weissman, Sherman M., Urban, Alexander E.

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Genome-wide synthetic lethal CRISPR screen identifies FIS1 as a genetic interactor of ALS-linked C9ORF72 von Chai, Noori, Haney, Michael S., Couthouis, Julien, Morgens, David W., Benjamin, Alyssa, Wu, Kathryn, Ousey, James, Fang, Shirleen, Finer, Sarah, Bassik, Michael C., Gitler, Aaron D.

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Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17 von Iram, Tal, Kern, Fabian, Kaur, Achint, Myneni, Saket, Morningstar, Allison R., Shin, Heather, Garcia, Miguel A., Yerra, Lakshmi, Palovics, Robert, Yang, Andrew C., Hahn, Oliver, Lu, Nannan, Shuken, Steven R., Haney, Michael S., Lehallier, Benoit, Iyer, Manasi, Luo, Jian, Zetterberg, Henrik, Keller, Andreas, Zuchero, J. Bradley, Wyss-Coray, Tony

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CD22 blockade restores homeostatic microglial phagocytosis in ageing brains von Pluvinage, John V., Haney, Michael S., Smith, Benjamin A. H., Sun, Jerry, Iram, Tal, Bonanno, Liana, Li, Lulin, Lee, Davis P., Morgens, David W., Yang, Andrew C., Shuken, Steven R., Gate, David, Scott, Madeleine, Khatri, Purvesh, Luo, Jian, Bertozzi, Carolyn R., Bassik, Michael C., Wyss-Coray, Tony

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Comprehensive, integrated, and phased whole-genome analysis of the primary ENCODE cell line K562 von Zhou, Bo, Ho, Steve S, Greer, Stephanie U, Zhu, Xiaowei, Bell, John M, Arthur, Joseph G, Spies, Noah, Zhang, Xianglong, Byeon, Seunggyu, Pattni, Reenal, Ben-Efraim, Noa, Haney, Michael S, Haraksingh, Rajini R, Song, Giltae, Ji, Hanlee P, Perrin, Dimitri, Wong, Wing H, Abyzov, Alexej, Urban, Alexander E

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Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration von Vest, Ryan T, Chou, Ching-Chieh, Zhang, Hui, Haney, Michael S, Li, Lulin, Laqtom, Nouf N, Chang, Betty, Shuken, Steven, Nguyen, Andy, Yerra, Lakshmi, Yang, Andrew C, Green, Carol, Tanga, Mary, Abu-Remaileh, Monther, Bassik, Michael C, Frydman, Judith, Luo, Jian, Wyss-Coray, Tony

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Detection and Quantification of Mosaic Genomic DNA Variation in Primary Somatic Tissues Using ddPCR: Analysis of Mosaic Transposable-Element Insertions, Copy-Number Variants, and S... von Zhou, Bo, Haney, Michael S., Zhu, Xiaowei, Pattni, Reenal, Abyzov, Alexej, Urban, Alexander E.

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Author Correction: Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17 von Iram, Tal, Kern, Fabian, Kaur, Achint, Myneni, Saket, Morningstar, Allison R., Shin, Heather, Garcia, Miguel A., Yerra, Lakshmi, Palovics, Robert, Yang, Andrew C., Hahn, Oliver, Lu, Nannan, Shuken, Steven R., Haney, Michael S., Lehallier, Benoit, Iyer, Manasi, Luo, Jian, Zetterberg, Henrik, Keller, Andreas, Zuchero, J. Bradley, Wyss-Coray, Tony

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Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain von Marschallinger, Julia, Iram, Tal, Zardeneta, Macy, Lee, Song E., Lehallier, Benoit, Haney, Michael S., Pluvinage, John V., Mathur, Vidhu, Hahn, Oliver, Morgens, David W., Kim, Justin, Tevini, Julia, Felder, Thomas K., Wolinski, Heimo, Bertozzi, Carolyn R., Bassik, Michael C., Aigner, Ludwig, Wyss-Coray, Tony

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Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain von Marschallinger, Julia, Iram, Tal, Zardeneta, Macy, Lee, Song E., Lehallier, Benoit, Haney, Michael S., Pluvinage, John V., Mathur, Vidhu, Hahn, Oliver, Morgens, David W., Kim, Justin, Tevini, Julia, Felder, Thomas K., Wolinski, Heimo, Bertozzi, Carolyn R., Bassik, Michael C., Aigner, Ludwig, Wyss-Coray, Tony

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A single-cell transcriptomic atlas characterizes ageing tissues in the mouse von Almanzar, Nicole, Antony, Jane, Baghel, Ankit S., Bakerman, Isaac, Bansal, Ishita, Barres, Ben A., Beachy, Philip A., Berdnik, Daniela, Bilen, Biter, Brownfield, Douglas, Cain, Corey, Chan, Charles K. F., Chen, Michelle B., Clarke, Michael F., Conley, Stephanie D., Darmanis, Spyros, Demers, Aaron, Demir, Kubilay, De Morree, Antoine, du Bois, Tessa Divita Haley, Ebadi, Hamid, Espinoza, F. Hernan, Fish, Matt, Gan, Qiang, George, Benson M., Gillich, Astrid, Gomez-Sjoberg, Rafael, Green, Foad, Genetiano, Geraldine, Gu, Xueying, Gulati, Gunsagar S., Hahn, Oliver, Haney, Michael Seamus, Hang, Yan, Harris, Lincoln, He, Mu, Hosseinzadeh, Shayan, Huang, Albin, Huang, Kerwyn Casey, Iram, Tal, Isobe, Taichi, Ives, Feather, Jones, Robert C., Kao, Kevin S., Karkanias, Jim, Karnam, Guruswamy, Keller, Andreas, Kershner, Aaron M., Khoury, Nathalie, Kim, Seung K., Kiss, Bernhard M., Kong, William, Krasnow, Mark A., Kumar, Maya E., Kuo, Christin S., Lam, Jonathan, Lee, Davis P., Lee, Song E., Lehallier, Benoit, Leventhal, Olivia, Li, Guang, Li, Qingyun, Liu, Ling, Lo, Annie, Lu, Wan-Jin, Lugo-Fagundo, Maria F., Manjunath, Anoop, May, Andrew P., Maynard, Ashley, McGeever, Aaron, Mckay, Marina, McNerney, M. Windy, Merrill, Bryan, Metzger, Ross J., Mignardi, Marco, Min, Dullei, Nabhan, Ahmad N., Neff, Norma F., Ng, Katharine M., Nguyen, Patricia K., Noh, Joseph, Nusse, Roel, Palovics, Robert, Patkar, Rasika, Peng, Weng Chuan, Penland, Lolita, Pisco, Angela Oliveira, Pollard, Katherine, Puccinelli, Robert, Qi, Zhen, Quake, Stephen R., Rando, Thomas A., Rulifson, Eric J., Schaum, Nicholas, Segal, Joe M., Sikandar, Shaheen S., Sinha, Rahul, Sit, Rene V., Sonnenburg, Justin, Staehli, Daniel

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Ageing hallmarks exhibit organ-specific temporal signatures von Schaum, Nicholas, Lehallier, Benoit, Hahn, Oliver, Pálovics, Róbert, Hosseinzadeh, Shayan, Lee, Song E., Sit, Rene, Lee, Davis P., Losada, Patricia Morán, Zardeneta, Macy E., Fehlmann, Tobias, Webber, James T., McGeever, Aaron, Calcuttawala, Kruti, Zhang, Hui, Berdnik, Daniela, Mathur, Vidhu, Tan, Weilun, Zee, Alexander, Tan, Michelle, Pisco, Angela Oliveira, Karkanias, Jim, Neff, Norma F., Keller, Andreas, Darmanis, Spyros, Quake, Stephen R., Wyss-Coray, Tony

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