The molecular genetics of Marfan syndrome and related disorders von Robinson, P N, Arteaga-Solis, E, Baldock, C, Collod-Béroud, G, Booms, P, De Paepe, A, Dietz, H C, Guo, G, Handford, P A, Judge, D P, Kielty, C M, Loeys, B, Milewicz, D M, Ney, A, Ramirez, F, Reinhardt, D P, Tiedemann, K, Whiteman, P, Godfrey, M

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Fibrillin-1, a calcium binding protein of extracellular matrix von Handford, P.A

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Solution Structure of a Pair of Calcium-Binding Epidermal Growth Factor-like Domains: Implications for the Marfan Syndrome and Other Genetic Disorders von Downing, A.K, Knott, V, Werner, J.M, Cardy, C.M, Campbell, I.D, Handford, P.A

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Twelve novel FBN1 mutations in Marfan syndrome and Marfan related phenotypes test the feasibility of FBN1 mutation testing in clinical practice von Halliday, D J, Hutchinson, S, Lonie, L, Hurst, J A, Firth, H, Handford, P A, Wordsworth, P

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Fibrillin: from domain structure to supramolecular assembly von Handford, P.A, Downing, A.K, Reinhardt, D.P, Sakai, L.Y

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Key residues involved in calcium-binding motifs in EGF-like domains von Handford, P. A, Mayhew, M, Baron, M, Winship, P. R, Campbell, I. D, Brownlee, G. G

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Molecular effects of calcium binding mutations in marfan syndrome depend on domain context von MCGETTRICK, A. J, KNOTT, V, WILLIS, A, HANDFORD, P. A

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Molecular analysis of eight mutations in FBN1 von HALLIDAY, D, HUTCHINSON, S, KETTLE, S, FIRTH, H, WORDSWORTH, P, HANDFORD, P. A

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The first EGF‐like domain from human factor IX contains a high‐affinity calcium binding site von Handford, P.A., Baron, M., Mayhew, M., Willis, A., Beesley, T., Brownlee, G.G., Campbell, I.D.

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Allelic variation in normal human FBN1 expression in a family with Marfan syndrome: a potential modifier of phenotype? von Hutchinson, Sarah, Furger, Andre, Halliday, Dorothy, Judge, Daniel P., Jefferson, Andrew, Dietz, Harry C., Firth, Helen, Handford, Penny A.

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Defective secretion of recombinant fragments of fibrillin-1: implications of protein misfolding for the pathogenesis of Marfan syndrome and related disorders von Whiteman, Pat, Handford, Penny A.

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Structural and Functional Properties of the Human Notch-1 Ligand Binding Region von Hambleton, Sophie, Valeyev, Najl V., Muranyi, Andreas, Knott, Vroni, Werner, Jörn M., McMichael, Andrew J., Handford, Penny A., Downing, A.Kristina

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The role of beta‐hydroxyaspartate and adjacent carboxylate residues in the first EGF domain of human factor IX von Rees, D. J., Jones, I. M., Handford, P. A., Walter, S. J., Esnouf, M. P., Smith, K. J., Brownlee, G. G.

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Solution Structure and Dynamics of a Calcium Binding Epidermal Growth Factor-like Domain Pair from the Neonatal Region of Human Fibrillin-1 von Smallridge, Rachel S, Whiteman, Pat, Werner, Jörn M, Campbell, Iain D, Handford, Penny A, Downing, A Kristina

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Effects of proline cis‐trans isomerization on TB domain secondary structure von Yuan, Xuemei, Werner, Jorn M., Campbell, Iain D., Downing, A. Kristina, Knott, Vron, Handford, Penny A.

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NMR analysis of cbEGF domains gives new insights into the structural consequences of a P1148A substitution in fibrillin-1 von Whiteman, P, Downing, A K, Handford, P A

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Solution structure of the transforming growth factor β-binding protein-like module, a domain associated with matrix fibrils von Yuan, Xuemei, Downing, A.Kristina, Knott, Vroni, Handford, Penny A.

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Metal ion dependency of microfibrils supports a rod-like conformation for fibrillin-1 calcium-binding epidermal growth factor-like domains von Cardy, C M, Handford, P A

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Backbone dynamics of a cbEGF domain pair in the presence of calcium von Werner, J M, Knott, V, Handford, P A, Campbell, I D, Downing, A K

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Calcium binding to fibrillin? von HANDFORD, P. A, MAYHEW, M, BROWNLEE, G. G

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