Genome-Wide Organization of GATA1 and TAL1 Determined at High Resolution von Han, G. Celine, Vinayachandran, Vinesh, Bataille, Alain R., Park, Bongsoo, Chan-Salis, Ka Yim, Keller, Cheryl A., Long, Maria, Mahony, Shaun, Hardison, Ross C., Pugh, B. Franklin

Volltext

Nivolumab Plus Ipilimumab for Metastatic Castration-Resistant Prostate Cancer: Preliminary Analysis of Patients in the CheckMate 650 Trial von Sharma, Padmanee, Pachynski, Russell K., Narayan, Vivek, Fléchon, Aude, Gravis, Gwenaelle, Galsky, Matthew D., Mahammedi, Hakim, Patnaik, Akash, Subudhi, Sumit K., Ciprotti, Marika, Simsek, Burcin, Saci, Abdel, Hu, Yanhua, Han, G. Celine, Fizazi, Karim

Volltext

Nivolumab in Patients with Advanced Platinum-resistant Urothelial Carcinoma: Efficacy, Safety, and Biomarker Analyses with Extended Follow-up from CheckMate 275 von Galsky, Matthew D., Saci, Abdel, Szabo, Peter M., Han, G. Celine, Grossfeld, Gary, Collette, Sandra, Siefker-Radtke, Arlene, Necchi, Andrea, Sharma, Padmanee

Volltext

The long tail of oncogenic drivers in prostate cancer von Armenia, Joshua, Wankowicz, Stephanie A. M., Liu, David, Gao, Jianjiong, Kundra, Ritika, Reznik, Ed, Chatila, Walid K., Chakravarty, Debyani, Han, G. Celine, Coleman, Ilsa, Montgomery, Bruce, Pritchard, Colin, Morrissey, Colm, Barbieri, Christopher E., Beltran, Himisha, Sboner, Andrea, Zafeiriou, Zafeiris, Miranda, Susana, Bielski, Craig M., Penson, Alexander V., Tolonen, Charlotte, Huang, Franklin W., Robinson, Dan, Wu, Yi Mi, Lonigro, Robert, Garraway, Levi A., Demichelis, Francesca, Kantoff, Philip W., Taplin, Mary-Ellen, Abida, Wassim, Taylor, Barry S., Scher, Howard I., Nelson, Peter S., de Bono, Johann S., Rubin, Mark A., Sawyers, Charles L., Chinnaiyan, Arul M., Schultz, Nikolaus, Van Allen, Eliezer M.

Volltext

Inherited DNA-Repair Defects in Colorectal Cancer von AlDubayan, Saud H., Giannakis, Marios, Moore, Nathanael D., Han, G. Celine, Reardon, Brendan, Hamada, Tsuyoshi, Mu, Xinmeng Jasmine, Nishihara, Reiko, Qian, Zhirong, Liu, Li, Yurgelun, Matthew B., Syngal, Sapna, Garraway, Levi A., Ogino, Shuji, Fuchs, Charles S., Van Allen, Eliezer M.

Volltext

Genomic evolution and chemoresistance in germ-cell tumours von Taylor-Weiner, Amaro, Zack, Travis, O’Donnell, Elizabeth, Guerriero, Jennifer L., Bernard, Brandon, Reddy, Anita, Han, G. Celine, AlDubayan, Saud, Amin-Mansour, Ali, Schumacher, Steven E., Litchfield, Kevin, Turnbull, Clare, Gabriel, Stacey, Beroukhim, Rameen, Getz, Gad, Carter, Scott L., Hirsch, Michelle S., Letai, Anthony, Sweeney, Christopher, Van Allen, Eliezer M

Volltext

Publisher Correction: The long tail of oncogenic drivers in prostate cancer von Armenia, Joshua, Wankowicz, Stephanie A. M., Liu, David, Gao, Jianjiong, Kundra, Ritika, Reznik, Ed, Chatila, Walid K., Chakravarty, Debyani, Han, G. Celine, Coleman, Ilsa, Montgomery, Bruce, Pritchard, Colin, Morrissey, Colm, Barbieri, Christopher E., Beltran, Himisha, Sboner, Andrea, Zafeiriou, Zafeiris, Miranda, Susana, Bielski, Craig M., Penson, Alexander V., Tolonen, Charlotte, Huang, Franklin W., Robinson, Dan, Wu, Yi Mi, Lonigro, Robert, Garraway, Levi A., Demichelis, Francesca, Kantoff, Philip W., Taplin, Mary-Ellen, Abida, Wassim, Taylor, Barry S., Scher, Howard I., Nelson, Peter S., de Bono, Johann S., Rubin, Mark A., Sawyers, Charles L., Chinnaiyan, Arul M., Schultz, Nikolaus, Van Allen, Eliezer M.

Volltext

Convergent Therapeutic Strategies to Overcome the Heterogeneity of Acquired Resistance in BRAF V600E Colorectal Cancer von Hazar-Rethinam, Mehlika, Kleyman, Marianna, Han, G Celine, Liu, David, Ahronian, Leanne G, Shahzade, Heather A, Chen, Lifeng, Parikh, Aparna R, Allen, Jill N, Clark, Jeffrey W, Kwak, Eunice L, Faris, Jason E, Murphy, Janet E, Hong, Theodore S, Van Seventer, Emily E, Nadres, Brandon, Hong, Catriona B, Gurski, Jr, Joseph M, Jessop, Nicholas A, Dias-Santagata, Dora, Iafrate, A John, Van Allen, Eliezer M, Corcoran, Ryan B

Volltext

Convergent Therapeutic Strategies to Overcome the Heterogeneity of Acquired Resistance in BRAFV600E Colorectal Cancer von Hazar-Rethinam, Mehlika, Kleyman, Marianna, Han, G Celine, Liu, David, Ahronian, Leanne G, Shahzade, Heather A, Chen, Lifeng, Parikh, Aparna R, Allen, Jill N, Clark, Jeffrey W, Kwak, Eunice L, Faris, Jason E, Murphy, Janet E, Hong, Theodore S, Van Seventer, Emily E, Nadres, Brandon, Hong, Catriona B, Gurski, Joseph M, Jessop, Nicholas A, Dias-Santagata, Dora, Iafrate, A John, Van Allen, Eliezer M, Corcoran, Ryan B

Volltext

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer von Pritchard, Colin C, Mateo, Joaquin, Walsh, Michael F, De Sarkar, Navonil, Abida, Wassim, Beltran, Himisha, Garofalo, Andrea, Gulati, Roman, Carreira, Suzanne, Eeles, Rosalind, Elemento, Olivier, Rubin, Mark A, Robinson, Dan, Lonigro, Robert, Hussain, Maha, Chinnaiyan, Arul, Vinson, Jake, Filipenko, Julie, Garraway, Levi, Taplin, Mary-Ellen, AlDubayan, Saud, Han, G. Celine, Beightol, Mallory, Morrissey, Colm, Nghiem, Belinda, Cheng, Heather H, Montgomery, Bruce, Walsh, Tom, Casadei, Silvia, Berger, Michael, Zhang, Liying, Zehir, Ahmet, Vijai, Joseph, Scher, Howard I, Sawyers, Charles, Schultz, Nikolaus, Kantoff, Philip W, Solit, David, Robson, Mark, Van Allen, Eliezer M, Offit, Kenneth, de Bono, Johann, Nelson, Peter S

Volltext

Abstract 2008: Pan-cancer profiling of the effect of biopsied site on tumor mutational burden measurements in a real-world data cohort von Papillon-Cavanagh, Simon, Gao, Chuan, Han, G. Celine, Walsh, Alice M.

Volltext

Abstract 5296: R2D2: An integrated analysis framework to infer the functional impact of single nucleotide variants (SNVs) using matched germline and tumor DNA and RNA sequencing da... von Imamovic, Alma, AlDubayan, Saud H., Moore, Nathanael, Han, Celine G., Reardon, Brendan, Allen, Eliezer M. Van

Volltext

Abstract 4890: Mutational signatures as biomarkers of response to nivolumab in metastatic bladder cancer von Han, G. Celine, Szabo, Peter M., Saci, Abdel, Walsh, Alice M., Kalinava, Natallia, Sasson, Ariella, Fischer, Bruce, Galsky, Matthew D., Sharma, Padmanee

Volltext

Initial results from a phase II study of nivolumab (NIVO) plus ipilimumab (IPI) for the treatment of metastatic castration-resistant prostate cancer (mCRPC; CheckMate 650) von Sharma, Padmanee, Pachynski, Russell Kent, Narayan, Vivek, Flechon, Aude, Gravis, Gwenaelle, Galsky, Matt D., Mahammedi, Hakim, Patnaik, Akash, Subudhi, Sumit Kumar, Ciprotti, Marika, Duan, Tao, Saci, Abdel, Hu, Sarah, Han, G. Celine, Fizazi, Karim

Volltext

Abstract 2905: Clinical and genomic resistance to second generation androgen blockade in paired biopsies of metastatic castration-resistant prostate cancer von Han, G. Celine, Hwang, Justin, Mullane, Stephanie A., Cibulskis, Carrie, Zhang, Zhenwei, McKay, Rana R., Carter, Scott L., Hahn, William C., Taplin, Mary-Ellen, Allen, Eliezer M. Van

Volltext

Enrichment of germline DNA-repair gene mutations in patients with colorectal cancer von Aldubayan, Saud H, Giannakis, Marios, Moore, Nathanael, Mu, Xinmeng Jasmine, Han, G. Celine, Nishihara, Reiko, Qian, Zhi Rong, Liu, Li, Ogino, Shuji, Garraway, Levi A., Fuchs, Charles S., Van Allen, Eliezer Mendel

Volltext

Abstract LB-A34: Modeling convergent therapeutic strategies to overcome the heterogeneity of acquired resistance in BRAF -mutant colorectal cancer von Hazar-Rethinam, Mehlika, Kleyman, Marianna, Han, G. Celine, Liu, David, Ahronian, Leanne G., Shahzade, Heather A., Chen, Lifeng, Parikh, Aparna R., Allen, Jill N., Clark, Jeffrey W., Kwak, Eunice L., Faris, Jason E., Murphy, Janet E., Hong, Theodore S., Seventer, Emily E. Van, Nadres, Brandon, Hong, Catriona B., Gurski, Joseph M., Jessop, Nicholas A., Dias-Santagata, Dora, Iafrate, A. John, Van Allen, Eli M., Corcoran, Ryan B.

Volltext

The long tail of significantly mutated genes in prostate cancer von Armenia, Joshua, Mullane, Stephanie Anne, Gao, JianJiong, Chakravarty, Debyani, Kundra, Ritika, Huang, Franklin W., Han, G. Celine, Robinson, Dan, Garraway, Levi A., Nelson, Peter, Rubin, Mark A., Taplin, Mary-Ellen, Abida, Wassim, Sawyers, Charles L., Chinnaiyan, Arul M., Kantoff, Philip W., De Bono, Johann S., Schultz, Nikolaus, Van Allen, Eliezer Mendel

Volltext

Mice lacking doublecortin and doublecortin-like kinase 2 display altered hippocampal neuronal maturation and spontaneous seizures von Kerjan, Géraldine, Koizumi, Hiroyuki, Han, Edward B, Dubé, Celine M, Djakovic, Stevan N, Patrick, Gentry N, Baram, Tallie Z, Heinemann, Stephen F, Gleeson, Joseph G

Volltext

Phase Ib Study of Lumretuzumab Plus Cetuximab or Erlotinib in Solid Tumor Patients and Evaluation of HER3 and Heregulin as Potential Biomarkers of Clinical Activity von Meulendijks, Didier, Jacob, Wolfgang, Voest, Emile E, Mau-Sorensen, Morten, Martinez-Garcia, Maria, Taus, Alvaro, Fleitas, Tania, Cervantes, Andres, Lolkema, Martijn P, Langenberg, Marlies H G, De Jonge, Maja J, Sleijfer, Stefan, Han, Ji-Youn, Calles, Antonio, Felip, Enriqueta, Kim, Sang-We, Schellens, Jan H M, Wilson, Sabine, Thomas, Marlene, Ceppi, Maurizio, Meneses-Lorente, Georgina, James, Ian, Vega-Harring, Suzana, Dua, Rajiv, Nguyen, Maitram, Steiner, Lori, Adessi, Celine, Michielin, Francesca, Bossenmaier, Birgit, Weisser, Martin, Lassen, Ulrik N

Volltext