Ultra-High Dose Rate (FLASH) Radiotherapy: Silver Bullet or Fool's Gold? von Wilson, Joseph D, Hammond, Ester M, Higgins, Geoff S, Petersson, Kristoffer

Volltext

Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity von Bader, Samuel B, Ma, Tiffany S, Simpson, Charlotte J, Liang, Jiachen, Maezono, Sakura Eri B, Olcina, Monica M, Buffa, Francesca M, Hammond, Ester M

Volltext

Links between the unfolded protein response and the DNA damage response in hypoxia: a systematic review von Bolland, Hannah, Ma, Tiffany S, Ramlee, Syafiq, Ramadan, Kristijan, Hammond, Ester M

Volltext

Replication Stress Drives Constitutive Activation of the DNA Damage Response and Radioresistance in Glioblastoma Stem-like Cells von Carruthers, Ross D, Ahmed, Shafiq U, Ramachandran, Shaliny, Strathdee, Karen, Kurian, Kathreena M, Hedley, Ann, Gomez-Roman, Natividad, Kalna, Gabriela, Neilson, Mathew, Gilmour, Lesley, Stevenson, Katrina H, Hammond, Ester M, Chalmers, Anthony J

Volltext

The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia von Ashton, Thomas M., Fokas, Emmanouil, Kunz-Schughart, Leoni A., Folkes, Lisa K., Anbalagan, Selvakumar, Huether, Melanie, Kelly, Catherine J., Pirovano, Giacomo, Buffa, Francesca M., Hammond, Ester M., Stratford, Michael, Muschel, Ruth J., Higgins, Geoff S., McKenna, William Gillies

Volltext

Replication Stress and Chromatin Context Link ATM Activation to a Role in DNA Replication von Olcina, Monica M., Foskolou, Iosifina P., Anbalagan, Selvakumar, Senra, Joana M., Pires, Isabel M., Jiang, Yanyan, Ryan, Anderson J., Hammond, Ester M.

Volltext

Challenges to DNA replication in hypoxic conditions von Ng, Natalie, Purshouse, Karin, Foskolou, Iosifina P., Olcina, Monica M., Hammond, Ester M.

Volltext

Inhibition of CDK4/CDK6 Enhances Radiosensitivity of HPV Negative Head and Neck Squamous Cell Carcinomas von Göttgens, Eva-Leonne, Bussink, Johan, Leszczynska, Katarzyna B., Peters, Hans, Span, Paul N., Hammond, Ester M.

Volltext

Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter von Wing, Peter A.C., Liu, Peter Jianrui, Harris, James M., Magri, Andrea, Michler, Thomas, Zhuang, Xiaodong, Borrmann, Helene, Minisini, Rosalba, Frampton, Nicholas R., Wettengel, Jochen M., Mailly, Laurent, D’Arienzo, Valentina, Riedl, Tobias, Nobre, Luis, Weekes, Michael P., Pirisi, Mario, Heikenwalder, Mathias, Baumert, Thomas F., Hammond, Ester M., Mole, David R., Protzer, Ulrike, Balfe, Peter, McKeating, Jane A.

Volltext

Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor von Skwarska, Anna, Calder, Ewen D.D., Sneddon, Deborah, Bolland, Hannah, Odyniec, Maria L., Mistry, Ishna N., Martin, Jennifer, Folkes, Lisa K., Conway, Stuart J., Hammond, Ester M.

Volltext

UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization von Nakashima, Ryota, Goto, Yoko, Koyasu, Sho, Kobayashi, Minoru, Morinibu, Akiyo, Yoshimura, Michio, Hiraoka, Masahiro, Hammond, Ester M., Harada, Hiroshi

Volltext

Contextual Synthetic Lethality of Cancer Cell Kill Based on the Tumor Microenvironment von CHAN, Norman, PIRES, Isabel M, HAMMOND, Ester M, BRISTOW, Robert G, BENCOKOVA, Zuzana, COACKLEY, Carla, LUOTO, Kaisa R, BHOGAL, Nirmal, LAKSHMAN, Minalini, GOTTIPATI, Ponnari, OLIVER, F. Javier, HELLEDAY, Thomas

Volltext

Targeting Hypoxic Cells through the DNA Damage Response von OLCINA, Monica, LECANE, Philip S, HAMMOND, Ester M

Volltext

Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs von O'Connor, Liam J, Cazares-Körner, Cindy, Saha, Jaideep, Evans, Charles N G, Stratford, Michael R L, Hammond, Ester M, Conway, Stuart J

Volltext

Hypoxia-induced SETX links replication stress with the unfolded protein response von Ramachandran, Shaliny, Ma, Tiffany S., Griffin, Jon, Ng, Natalie, Foskolou, Iosifina P., Hwang, Ming-Shih, Victori, Pedro, Cheng, Wei-Chen, Buffa, Francesca M., Leszczynska, Katarzyna B., El-Khamisy, Sherif F., Gromak, Natalia, Hammond, Ester M.

Volltext

Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands von Hewings, David S, Fedorov, Oleg, Filippakopoulos, Panagis, Martin, Sarah, Picaud, Sarah, Tumber, Anthony, Wells, Christopher, Olcina, Monica M, Freeman, Katherine, Gill, Andrew, Ritchie, Alison J, Sheppard, David W, Russell, Angela J, Hammond, Ester M, Knapp, Stefan, Brennan, Paul E, Conway, Stuart J

Volltext

Hypoxia‐mediated regulation of DDX5 through decreased chromatin accessibility and post‐translational targeting restricts R‐loop accumulation von Leszczynska, Katarzyna B., Dzwigonska, Monika, Estephan, Hala, Moehlenbrink, Jutta, Bowler, Elizabeth, Giaccia, Amato J., Mieczkowski, Jakub, Kaminska, Bozena, Hammond, Ester M.

Volltext

Effects of Acute versus Chronic Hypoxia on DNA Damage Responses and Genomic Instability von PIRES, Isabel M, BENCOKOVA, Zuzana, MILANI, Manuela, FOLKES, Lisa K, LI, Ji-Liang, STRATFORD, Mike R, HARRIS, Adrian L, HAMMOND, Ester M

Volltext

KDM4A regulates HIF-1 levels through H3K9me3 von Dobrynin, Grzegorz, McAllister, Tom E., Leszczynska, Katarzyna B., Ramachandran, Shaliny, Krieg, Adam J., Kawamura, Akane, Hammond, Ester M.

Volltext

A novel method for autophagy detection in primary cells: Impaired levels of macroautophagy in immunosenescent T cells von Phadwal, Kanchan, Alegre-Abarrategui, Javier, Watson, Alexander Scarth, Pike, Luke, Anbalagan, Selvakumar, Hammond, Ester M., Wade-Martins, Richard, McMichael, Andrew, Klenerman, Paul, Simon, Anna Katharina

Volltext