Sirtuins are crucial regulators of T cell metabolism and functions von Hamaidi, Imene, Kim, Sungjune

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Epigenetic dysregulation of immune-related pathways in cancer: bioinformatics tools and visualization von Berglund, Anders, Putney, Ryan M., Hamaidi, Imene, Kim, Sungjune

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Epigenetic state determines the in vivo efficacy of STING agonist therapy von Falahat, Rana, Berglund, Anders, Perez-Villarroel, Patricio, Putney, Ryan M., Hamaidi, Imene, Kim, Sungjune, Pilon-Thomas, Shari, Barber, Glen N., Mulé, James J.

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An FGFR3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers von Mahe, Mélanie, Dufour, Florent, Neyret‐Kahn, Hélène, Moreno‐Vega, Aura, Beraud, Claire, Shi, Mingjun, Hamaidi, Imene, Sanchez‐Quiles, Virginia, Krucker, Clementine, Dorland‐Galliot, Marion, Chapeaublanc, Elodie, Nicolle, Remy, Lang, Hervé, Pouponnot, Celio, Massfelder, Thierry, Radvanyi, François, Bernard‐Pierrot, Isabelle

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Methylation of immune synapse genes modulates tumor immunogenicity von Berglund, Anders, Mills, Matthew, Putney, Ryan M., Hamaidi, Imene, Mule, James, Kim, Sungjune

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The Lim1 oncogene as a new therapeutic target for metastatic human renal cell carcinoma von Hamaidi, Imène, Coquard, Catherine, Danilin, Sabrina, Dormoy, Valérian, Béraud, Claire, Rothhut, Sylvie, Barthelmebs, Mariette, Benkirane-Jessel, Nadia, Lindner, Véronique, Lang, Hervé, Massfelder, Thierry

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Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells von Hamaidi, Imene, Zhang, Lin, Kim, Nayoung, Wang, Min-Hsuan, Iclozan, Cristina, Fang, Bin, Liu, Min, Koomen, John M., Berglund, Anders E., Yoder, Sean J., Yao, Jiqiang, Engelman, Robert W., Creelan, Ben C., Conejo-Garcia, Jose R., Antonia, Scott J., Mulé, James J., Kim, Sungjune

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Combined nivolumab and ipilimumab with or without stereotactic body radiation therapy for advanced Merkel cell carcinoma: a randomised, open label, phase 2 trial von Kim, Sungjune, Wuthrick, Evan, Blakaj, Dukagjin, Eroglu, Zeynep, Verschraegen, Claire, Thapa, Ram, Mills, Matthew, Dibs, Khaled, Liveringhouse, Casey, Russell, Jeffery, Caudell, Jimmy J, Tarhini, Ahmad, Markowitz, Joseph, Kendra, Kari, Wu, Richard, Chen, Dung-Tsa, Berglund, Anders, Michael, Lauren, Aoki, Mia, Wang, Min-Hsuan, Hamaidi, Imene, Cheng, Pingyan, de la Iglesia, Janis, Slebos, Robbert J, Chung, Christine H, Knepper, Todd C, Moran-Segura, Carlos M, Nguyen, Jonathan V, Perez, Bradford A, Rose, Trevor, Harrison, Louis, Messina, Jane L, Sondak, Vernon K, Tsai, Kenneth Y, Khushalani, Nikhil I, Brohl, Andrew S

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1085 The NAD+ dependent deacetylase Sirt2 is a negative regulator of the JAK/STAT pathway in effector t cells von Hamaidi, Imene, Zhang, Lin, Cheng, Pingyan, Min-Hsuan Wang, Johnson, Erika, Fang, Bin, Kim, Sungjune

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Abstract 1635: Sirt2 blockade promotes T cell metabolism and restores the anti-tumor immunity von Hamaidi, Imene, Zhang, Lin, Kim, Nayoung, Wang, Min Hsuan, Iclozan, Cristina, Fang, Bin, Liu, Min, Koomen, John M., Berglund, Anders E., Yoder, Sean J., Yao, Jiqiang, Engelman, Robert W., Creelan, Ben C., Conejo-Garcia, Jose R., Mulé, James J., Antonia, Scott J., Kim, Sungjune

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A Randomized Phase II Trial of Combined Nivolumab and Ipilimumab with or without Stereotactic Body Radiation Therapy for Advanced Merkel Cell Carcinoma von Kim, Sungjune, Wuthrick, Evan, Blakaj, Dukagjin, Eroglu, Zeynep, Verschraegen, Claire, Thapa, Ram, Mills, Matthew, Dibs, Khaled, Liveringhouse, Casey, Russell, Jeffery, Caudell, Jimmy J., Tarhini, Ahmad, Markowitz, Joseph, Kendra, Kari, Wu, Richard, Chen, Dung-Tsa, Berglund, Anders, Michael, Lauren, Aoki, Mia, Wang, Min-Hsuan, Hamaidi, Imene, Cheng, Pingyan, de la Iglesia, Janis, Slebos, Robbert J., Chung, Christine H., Knepper, Todd C., Moran-Segura, Carlos M., Nguyen, Jonathan V., Perez, Bradford, Rose, Trevor, Harrison, Louis, Messina, Jane L., Sondak, Vernon K., Tsai, Kenneth Y., Khushalani, Nikhil I., Brohl, Andrew S.

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Methylation of immune synapse genes modulates tumor immunogenicity von Berglund, Anders, Mills, Matthew, Putney, Ryan M, Hamaidi, Imene, Mule, James, Kim, Sungjune

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An FGFR 3/ MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers von Mahe, Mélanie, Dufour, Florent, Neyret‐Kahn, Hélène, Moreno‐Vega, Aura, Beraud, Claire, Shi, Mingjun, Hamaidi, Imene, Sanchez‐Quiles, Virginia, Krucker, Clementine, Dorland‐Galliot, Marion, Chapeaublanc, Elodie, Nicolle, Remy, Lang, Hervé, Pouponnot, Celio, Massfelder, Thierry, Radvanyi, François, Bernard‐Pierrot, Isabelle

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93 Targeting sirt2 rescues the metabolic fitness and effector functions of tumor-reactive T cells within the metabolically restricted tumor microenvironment von Hamaidi, Imene, Zhang, Lin, Kim, Nayoung, Min-Hsuan Wang, Iclozan, Cristina, Fang, Bin, Liu, Min, Koomen, John, Berglund, Anders, Yoder, Sean, Yao, Jiqiang, Engelman, Robert, Creelan, Ben, Conejo-Garcia, Jose, Scott, Antonia, Mule, James, Kim, Sungjune

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Implication du facteur développemental Lim1, un nouvel oncogène, dans le cancer du rein humain avancé von Hamaidi, Imene

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ENGINEERED IMMUNE CELLS WITH REDUCED SIRT6 EXPRESSION von KIM, Sungjune, HAMAIDI, Imene

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Polydiacetylenic nanofibers as new siRNA vehicles for in vitro and in vivo delivery von Neuberg, P, Hamaidi, I, Danilin, S, Ripoll, M, Lindner, V, Nothisen, M, Wagner, A, Kichler, A, Massfelder, T, Remy, J-S

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