Methylation of γ‑Carboxylated Glu (Gla) Allows Detection by Liquid Chromatography–Mass Spectrometry and the Identification of Gla Residues in the γ‑Glutamyl Carboxylase von Hallgren, K. W, Zhang, D, Kinter, M, Willard, B, Berkner, K. L

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Identification of the Vitamin K-Dependent Carboxylase Active Site: Cys-99 and Cys-450 Are Required for Both Epoxidation and Carboxylation von Pudota, B. Nirmala, Miyagi, Masaru, Hallgren, Kevin W., West, Karen A., Crabb, John W., Misono, Kunio S., Berkner, Kathleen L.

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Identification of Sequences within the γ-Carboxylase That Represent a Novel Contact Site with Vitamin K-dependent Proteins and That Are Required for Activity von Pudota, B. Nirmala, Hommema, Eric L., Hallgren, Kevin W., McNally, Beth A., Lee, Susan, Berkner, Kathleen L.

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r-VKORC1 Expression in Factor IX BHK Cells Increases the Extent of Factor IX Carboxylation but Is Limited by Saturation of Another Carboxylation Component or by a Shift in the Rate... von Hallgren, Kevin W, Qian, Wen, Yakubenko, Anna V, Runge, Kurt W, Berkner, Kathleen L

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Carboxylase Overexpression Effects Full Carboxylation but Poor Release and Secretion of Factor IX:  Implications for the Release of Vitamin K-Dependent Proteins von Hallgren, Kevin W, Hommema, Eric L, McNally, Beth A, Berkner, Kathleen L

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The Vitamin K-dependent Carboxylase Has Been Acquired by Leptospira Pathogens and Shows Altered Activity That Suggests a Role Other than Protein Carboxylation von Rishavy, Mark A., Hallgren, Kevin W., Yakubenko, Anna V., Zuerner, Richard L., Runge, Kurt W., Berkner, Kathleen L.

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A New Model for Vitamin K-Dependent Carboxylation: The Catalytic Base That Deprotonates Vitamin K Hydroquinone Is Not Cys but an Activated Amine von Rishavy, Mark A., Pudota, B. Nirmala, Hallgren, Kevin W., Qian, Wen, Yakubenko, Anna V., Song, Jee-Hyeon, Runge, Kurt W., Berkner, Kathleen L., Majerus, Philip W.

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Evidence for neutrino emission from the nearby active galaxy NGC 1068 von Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alameddine, J. M., Alispach, C., Alves, A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Axani, S., Bai, X., Balagopal V., A., Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baur, S., Bay, R., Beatty, J. J., Becker, K.-H., Becker Tjus, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Boddenberg, M., Bontempo, F., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bradascio, F., Braun, J., Brinson, B., Bron, S., Brostean-Kaiser, J., Browne, S., Burgman, A., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, K., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., Delgado López, D., Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T.

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IceCube-Gen2: the window to the extreme Universe von Abbasi, R, Ackermann, M, Allison, P, Andeen, K, Arlen, T C, Barbano, A, Basu, V, Baur, S, Becker, K-H, Besson, D Z, Böser, S, Böttcher, J, Bourbeau, J, Braun, J, Bron, S, Busse, R S, Chen, P, Cheung, E, Choi, S, Clark, K, Connolly, A, Correa, P, Cowen, D F, Cross, R, Deaconu, C, De Kockere, S, Dembinski, H, Desiati, P, Díaz-Vélez, J C, Felde, J, Gallagher, J, Ganster, E, Gerhard, L, Glaser, C, Glüsenkamp, T, Gonzalez, J G, Griffith, Z, Haack, C, Haugen, J, Heinen, D, Hellauer, R, Hoffmann, R, Hoinka, T, Hughes, K, Hultqvist, K, In, S, Kang, X, Kappesser, D, Katori, T, Kellermann, M, Kelley, J L, Klein, S R, Koirala, R, Kovacevich, M, Krückl, G, Lahmann, R, Larson, M J, Lohfink, E, Lünemann, J, Madsen, J, Mancina, S, Maruyama, R, Mase, K, Mockler, D, Montaruli, T, Nelles, A, Niederhausen, H, Oehler, M, O’Sullivan, E, Pan, Y, Pieper, S, Reusch, S, Rhode, W, Roberts, E J, Rongen, M, Rott, C, Ryckbosch, D, Safa, I, Santander, M, Satalecka, K, Schieler, H, Shefali, S, Smith, D, Soedingrekso, J, Soldin, D, Southall, D, Spiczak, G M, Steuer, A, Stürwald, T, Stuttard, T, Ter-Antonyan, S, Terliuk, A, Tosi, D, Tselengidou, M, Turcati, A, Ty, B, Weldert, J, Wiebusch, C H, Yoshida, S, Zhang, Z

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Improved Characterization of the Astrophysical Muon–neutrino Flux with 9.5 Years of IceCube Data von Abbasi, R., Ahrens, M., Alispach, C., Amin, N. M., Anderson, T., Argüelles, C., Ashida, Y., Becker, K.-H., Bindig, D., Bontempo, F., Bron, S., Clark, B. A., Clark, K., Desiati, P., de Wasseige, G., Díaz-Vélez, J. C., Engel, R., Evans, J., Fazely, A. R., Feigl, N., Fiedlschuster, S., Fox, D., Franckowiak, A., Fritz, A., Gallagher, J., Garcia, A., Glüsenkamp, T., Goswami, S., Grant, D., Gutjahr, P., Halliday, R., Minh, M. Ha, Harnisch, A. A., Hebecker, D., Hickford, S., Hill, C., Huber, M., Iovine, N., Ishihara, A., Japaridze, G. S., Jin, M., Kang, X., Karle, A., Katz, U., Kelley, J. L., Koirala, R., Kolanoski, H., Kowalski, M., Lad, N., Gualda, C. Lagunas, Lanfranchi, J. L., Lazar, J. P., Mariscal, C. J. Lozano, Lu, L., Lyu, Y., Madsen, J., Meier, M., Meighen-Berger, S., Moore, R. W., Naumann, U., Necker, J., Nguyễn, L. V., Nisa, M. U., de los Heros, C. Pérez, Peterson, J., Pizzuto, A., Rodriguez, M. Prado, Price, P. B., Pries, B., Rameez, M., Rawlins, K., Rehman, A., Reichherzer, P., Renzi, G., Robertson, S., Ruhe, T., Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Sarkar, S., Schwefer, G., Smithers, B., Soedingrekso, J., Stachurska, J., Stein, R., Stezelberger, T., Stuttard, T., Toscano, S., Tselengidou, M., Valtonen-Mattila, N., Vannerom, D., Watson, T. B., Whitehorn, N., Woschnagg, K., Wrede, G., Yu, S., Zhelnin, P.

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Detection of a particle shower at the Glashow resonance with IceCube von Aartsen, M. G, Abbasi, R, Ackermann, M, Adams, J, Aguilar, J. A, Ahlers, M, Ahrens, M, Alispach, C, Amin, N.M, Andeen, K, Anderson, T, Ansseau, I, Anton, G, Arguelles, C, Auffenberg, J, Axani, S, Bagherpour, H

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Multimessenger observations of a flaring blazar coincident with high-energy neutrino IceCube-170922A von Aartsen, Mark, Ackermann, Markus, Adams, Jenni, Aguilar, Juan Antonio, Ahlers, Markus, Ahrens, Maryon, Al Samarai, Imen, Altmann, David, Andeen, Karen, Anderson, Tyler, Ansseau, Isabelle, Anton, Gisela, Argüelles, Carlos, Auffenberg, Jan, Axani, Spencer, Bagherpour, Hadis, Bai, Xinhua, Barron, Jared, Barwick, Steve, Baum, Volker, Bay, Ryan, Beatty, James, Becker, Karl Heinz, Tjus, Julia, BenZvi, Segev, Berley, David, Bernardini, Elisa, Besson, David, Binder, Gary, Bindig, Daniel, Blaufuss, Erik, Blot, Summer, Bohm, Christian, Boerner, Mathis, Bos, Fabian, Boeser, Sebastian, Botner, Olga, Bourbeau, Etienne, Bourbeau, James, Bradascio, Federica, Braun, Jim, Brenzke, Martin, Bretz, Hans-Peter, Bron, Stephanie, Brostean-Kaiser, Jannes, Burgman, Alexander, Busse, Raffaela, Carver, Tessa, Cheng, Edward, Chirkin, Dmitry, Christov, Asen, Clark, Ken, Classen, Lew, Coenders, S., Collin, Gabriel, Conrad, Janet, Coppin, Paul, Correa, Pablo, Cowen, Doug, Cross, Robert, Dave, Pranav, Day, Melanie, de Andre, Joao Pedro A M, De Clercq, Catherine, Delaunay, James, Dembinski, Hans, DeRidder, Sam, Desiati, Paolo, de Vries, Krijn, DeWasseige, Gwenhael, DeWith, Meike, DeYoung, Ty, Díaz-Vélez, Juan Carlos, Di Lorenzo, Vincenzo, Dujmovic, Hrvoje, Dumm, Jonathan, Dunkman, Matt, Dvorak, Emily, Eberhardt, Benjamin, Ehrhardt, Thomas, Eichmann, Bjorn, Eller, Philipp, Evenson, Paul, Fahey, Sam, Fazely, Ali, Felde, John, Filimonov, Kirill, Finley, Chad, Flis, Samuel, Franckowiak, Anna, Friedman, Elizabeth, Fritz, Alexander, Gaisser, Tom, Gallagher, Jay, Gerhardt, Lisa, Ghorbani, Kevin, Glauch, Theo, Gluesenkamp, Thorsten, Goldschmidt, Azriel, Gonzalez, Javier

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Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies von Albrecht, Inka, Wick, Cecilia, Hallgren, Åsa, Tjärnlund, Anna, Nagaraju, Kanneboyina, Andrade, Felipe, Thompson, Kathryn, Coley, William, Phadke, Aditi, Diaz-Gallo, Lina-Marcela, Bottai, Matteo, Nennesmo, Inger, Chemin, Karine, Herrath, Jessica, Johansson, Karin, Wikberg, Anders, Ytterberg, A Jimmy, Zubarev, Roman A, Danielsson, Olof, Krystufkova, Olga, Vencovsky, Jiri, Landegren, Nils, Wahren-Herlenius, Marie, Padyukov, Leonid, Kämpe, Olle, Lundberg, Ingrid E

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Time-Integrated Neutrino Source Searches with 10 Years of IceCube Data von Aartsen, M G, Ackermann, M, Adams, J, Aguilar, J A, Ahlers, M, Ahrens, M, Alispach, C, Andeen, K, Anderson, T, Ansseau, I, Anton, G, Argüelles, C, Auffenberg, J, Axani, S, Backes, P, Bagherpour, H, Bai, X, Balagopal, A, Barbano, A, Barwick, S W, Bastian, B, Baum, V, Baur, S, Bay, R, Beatty, J J, Becker, K-H, Becker Tjus, J, BenZvi, S, Berley, D, Bernardini, E, Besson, D Z, Binder, G, Bindig, D, Blaufuss, E, Blot, S, Bohm, C, Börner, M, Böser, S, Botner, O, Böttcher, J, Bourbeau, E, Bourbeau, J, Bradascio, F, Braun, J, Bron, S, Brostean-Kaiser, J, Burgman, A, Buscher, J, Busse, R S, Carver, T, Chen, C, Cheung, E, Chirkin, D, Choi, S, Clark, K, Classen, L, Coleman, A, Collin, G H, Conrad, J M, Coppin, P, Correa, P, Cowen, D F, Cross, R, Dave, P, De Clercq, C, DeLaunay, J J, Dembinski, H, Deoskar, K, De Ridder, S, Desiati, P, de Vries, K D, de Wasseige, G, de With, M, DeYoung, T, Diaz, A, Díaz-Vélez, J C, Dujmovic, H, Dunkman, M, Dvorak, E, Eberhardt, B, Ehrhardt, T, Eller, P, Engel, R, Evenson, P A, Fahey, S, Fazely, A R, Felde, J, Filimonov, K, Finley, C, Fox, D, Franckowiak, A, Friedman, E, Fritz, A, Gaisser, T K, Gallagher, J, Ganster, E, Garrappa, S, Gerhardt, L, Ghorbani, K, Glauch, T

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Sedentary behavior and lifespan brain health von Zou, Liye, Herold, Fabian, Cheval, Boris, Wheeler, Michael J., Pindus, Dominika M., Erickson, Kirk I., Raichlen, David A., Alexander, Gene E., Müller, Notger G., Dunstan, David W., Kramer, Arthur F., Hillman, Charles H., Hallgren, Mats, Ekelund, Ulf, Maltagliati, Silvio, Owen, Neville

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Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor von Stepan, Antonia F, Subramanyam, Chakrapani, Efremov, Ivan V, Dutra, Jason K, O’Sullivan, Theresa J, DiRico, Kenneth J, McDonald, W. Scott, Won, Annie, Dorff, Peter H, Nolan, Charles E, Becker, Stacey L, Pustilnik, Leslie R, Riddell, David R, Kauffman, Gregory W, Kormos, Bethany L, Zhang, Liming, Lu, Yasong, Capetta, Steven H, Green, Michael E, Karki, Kapil, Sibley, Evelyn, Atchison, Kevin P, Hallgren, Andrew J, Oborski, Christine E, Robshaw, Ashley E, Sneed, Blossom, O’Donnell, Christopher J

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Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis von Sveidahl Johansen, Olivia, Ma, Tao, Hansen, Jakob Bondo, Markussen, Lasse Kruse, Schreiber, Renate, Reverte-Salisa, Laia, Dong, Hua, Christensen, Dan Ploug, Sun, Wenfei, Gnad, Thorsten, Karavaeva, Iuliia, Nielsen, Thomas Svava, Kooijman, Sander, Cero, Cheryl, Dmytriyeva, Oksana, Shen, Yachen, Razzoli, Maria, O’Brien, Shannon L., Kuipers, Eline N., Nielsen, Carsten Haagen, Orchard, William, Willemsen, Nienke, Jespersen, Naja Zenius, Lundh, Morten, Sustarsic, Elahu Gosney, Hallgren, Cecilie Mørch, Frost, Mikkel, McGonigle, Seth, Isidor, Marie Sophie, Broholm, Christa, Pedersen, Oluf, Hansen, Jacob Bo, Grarup, Niels, Hansen, Torben, Kjær, Andreas, Granneman, James G., Babu, M. Madan, Calebiro, Davide, Nielsen, Søren, Rydén, Mikael, Soccio, Raymond, Rensen, Patrick C.N., Treebak, Jonas Thue, Schwartz, Thue Walter, Emanuelli, Brice, Bartolomucci, Alessandro, Pfeifer, Alexander, Zechner, Rudolf, Scheele, Camilla, Mandrup, Susanne, Gerhart-Hines, Zachary

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Multi-messenger Observations of a Binary Neutron Star Merger von Agathos, M, Agatsuma, K, Allocca, A, Barta, D, Bloemen, S, Bouffanais, Y, Broida, J E, Calloni, E, Chincarini, A, Chmiel, T, Cho, M, Covas, P B, DeBra, D, Gehrels, N, Greco, G, Kim, W, Krishnan, B, Lartaux-Vollard, A, Li, T G F, Miller, J, Minazzoli, O, Paoletti, F, Pele, A, Piergiovanni, F, Rowan, S, Schofield, R M S, Steinlechner, J, Tanner, D B, Tse, M, Usman, S A, Wen, L, Wimmer, M H, J Becker Tjus, Besson, D Z, Collin, G H, De Clercq, C, Glüsenkamp, T, Naumann, U, Rameez, M, Unger, E, Wills, L, Woolsey, E, Huang, Y, Li, X B, M Wu, Fassi, F, Piattelli, P, Sieger, C, Krimm, H A, Neilsen, E, Mapelli, M, Acero, F, Cameron, R A, Dubois, R, Suson, D J, Onken, C A, Tucker, B E, Shang, Z, A de Ugarte-Postigo, Fujii, Y I, Tlatov, A G, Garcia, J A, Jacobs, Bob, Mooley, K, Palliyaguru, N, Chambers, K C, Magnier, E A, Kankare, E, Botticella, M T, Dennefeld, M, Elias-Rosa, N, Kerzendorf, W E, Mattila, S, García, J, Böttcher, M, Marcowith, A, Pelletier, G, Rieger, F, Rulten, C B, Shiningayamwe, K, Alfaro, R, Arceo, R, Bernal, A, Cotti, U, Lauer, R J, Yapici, T, Zhou, H, Debatin, J, Farmer, J, Hojvat, C, M A Leigui de Oliveira, Lopes, L, Mockler, D, Naranjo, I, Petrera, S, Ramos-Pollan, R, Scherini, V, Wahlberg, H, Zavrtanik, M, Kutyrev, A

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Evidence for High-Energy Extraterrestrial Neutrinos at the IceCube Detector von Aartsen, M G, Abbasi, R, Abdou, Y, Ackermann, M, Adams, J, Aguilar, J A, Ahlers, M, Altmann, D, Auffenberg, J, Bai, X, Baker, M, Barwick, S W, Baum, V, Bay, R, Beatty, J J, Bechet, S, Becker Tjus, J, Becker, K-H, Benabderrahmane, M L, BenZvi, S, Berghaus, P, Berley, D, Bernardini, E, Bernhard, A, Bertrand, D, Besson, D Z, Binder, G, Bindig, D, Bissok, M, Blaufuss, E, Blumenthal, J, Boersma, D J, Bohaichuk, S, Bohm, C, Bose, D, Böser, S, Botner, O, Brayeur, L, Bretz, H-P, Brown, A M, Bruijn, R, Brunner, J, Carson, M, Casey, J, Casier, M, Chirkin, D, Christov, A, Christy, B, Clark, K, Clevermann, F, Coenders, S, Cohen, S, Cowen, D F, Cruz Silva, A H, Danninger, M, Daughhetee, J, Davis, J C, Day, M, De Clercq, C, De Ridder, S, Desiati, P, de Vries, K D, de With, M, DeYoung, T, Díaz-Vélez, J C, Dunkman, M, Eagan, R, Eberhardt, B, Eichmann, B, Eisch, J, Ellsworth, R W, Euler, S, Evenson, P A, Fadiran, O, Fazely, A R, Fedynitch, A, Feintzeig, J, Feusels, T, Filimonov, K, Finley, C, Fischer-Wasels, T, Flis, S, Franckowiak, A, Frantzen, K, Fuchs, T, Gaisser, T K, Gallagher, J, Gerhardt, L, Gladstone, L, Glüsenkamp, T, Goldschmidt, A, Golup, G, Gonzalez, J G, Goodman, J A, Góra, D, Grandmont, D T, Grant, D, Groß, A, Ha, C, Haj Ismail, A

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THE CONTRIBUTION OF FERMI-2LAC BLAZARS TO DIFFUSE TEV-PEV NEUTRINO FLUX von Ahrens, M., Ansseau, I., Auffenberg, J., Beatty, J. J., Tjus, J. Becker, Berley, D., Besson, D. Z., Bissok, M., Blaufuss, E., Blot, S., Bos, F., Botner, O., Casier, M., Cheung, E., Christov, A., Classen, L., Day, M., Clercq, C. De, Ridder, S. De, Vries, K. D. de, Wasseige, G. de, Dumm, J. P., Euler, S., Fahey, S., Fazely, A. R., Felde, J., Filimonov, K., Finley, C., Gaisser, T. K., Ghorbani, K., Giang, W., Goldschmidt, A., Góra, D., Ismail, A. Haj, Hansmann, T., Hanson, K., Helbing, K., Huelsnitz, W., Japaridze, G. S., Jero, K., Jurkovic, M., Karg, T., Karle, A., Kauer, M., Kemp, J., Kiryluk, J., Kolanoski, H., Köpke, L., Kowalski, M., Krüger, C., Kurahashi, N., Lanfranchi, J. L., Lennarz, D., Leuner, J., Maggi, G., Mandelartz, M., Mase, K., McNally, F., Meagher, K., Meli, A., Meures, T., Niederhausen, H., Nowicki, S. C., Olivas, A., Pankova, D. V., Pepper, J. A., Rädel, L., Rawlins, K., Riedel, B., Robertson, S., Ruhe, T., Ryckbosch, D., Rysewyk, D., Herrera, S. E. Sanchez, Schimp, M., Seckel, D., Seunarine, S., Spiczak, G. M., Ström, R., Sullivan, G. W., Taboada, I., Terliuk, A., Teši, G., Toscano, S., Turcati, A., Usner, M., Vallecorsa, S., Vanheule, S., Wallace, A., Weaver, Ch, Whelan, B. J., Wickmann, S., Wiebe, K., Wolf, M., Woschnagg, K., Xu, D. L., Xu, X. W., Xu, Y., Yodh, G., Zoll, M.

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