The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respirator... von Thistlethwaite, Fiona C., Gilham, David E., Guest, Ryan D., Rothwell, Dominic G., Pillai, Manon, Burt, Deborah J., Byatte, Andrea J., Kirillova, Natalia, Valle, Juan W., Sharma, Surinder K., Chester, Kerry A., Westwood, Nigel B., Halford, Sarah E. R., Nabarro, Stephen, Wan, Susan, Austin, Eric, Hawkins, Robert E.

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How do site‐specific DNA‐binding proteins find their targets? von Halford, Stephen E., Marko, John F.

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A randomised, phase II trial of the DNA-hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in combination with carboplatin vs carboplatin alone in patients with recurrent, p... von Glasspool, R M, Brown, R, Gore, M E, Rustin, G J S, McNeish, I A, Wilson, R H, Pledge, S, Paul, J, Mackean, M, Hall, G D, Gabra, H, Halford, S E R, Walker, J, Appleton, K, Ullah, R, Kaye, S

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Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues von Gajdasik, Dominika W., Gaspal, Fabrina, Halford, Emily E., Fiancette, Remi, Dutton, Emma E., Willis, Claire, Rückert, Timo, Romagnani, Chiara, Gerard, Audrey, Bevington, Sarah L., MacDonald, Andrew S., Botto, Marina, Vyse, Timothy, Withers, David R.

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Measurement of the Contributions of 1D and 3D Pathways to the Translocation of a Protein along DNA von Darren M. Gowers, Geoffrey G. Wilson, Halford, Stephen E., von Hippel, Peter H.

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Three-dimensional imaging of carbonyl sulfide and ethyl iodide photodissociation using the pixel imaging mass spectrometry camera von Amini, K, Blake, S, Brouard, M, Burt, M B, Halford, E, Lauer, A, Slater, C S, Lee, J W L, Vallance, C

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Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells von Withers, David R, Hepworth, Matthew R, Wang, Xinxin, Mackley, Emma C, Halford, Emily E, Dutton, Emma E, Marriott, Clare L, Brucklacher-Waldert, Verena, Veldhoen, Marc, Kelsen, Judith, Baldassano, Robert N, Sonnenberg, Gregory F

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Exon 3 β-catenin mutations are specifically associated with colorectal carcinomas in hereditary non-polyposis colorectal cancer syndrome von Johnson, V, Volikos, E, Halford, S E, Eftekhar Sadat, E T, Popat, S, Talbot, I, Truninger, K, Martin, J, Jass, J, Houlston, R, Atkin, W, Tomlinson, I P M, Silver, A R J

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A Cancer Research UK First Time in Human Phase I Trial of IMA950 (Novel Multipeptide Therapeutic Vaccine) in Patients with Newly Diagnosed Glioblastoma von Rampling, Roy, Peoples, Sharon, Mulholland, Paul J, James, Allan, Al-Salihi, Omar, Twelves, Christopher J, McBain, Catherine, Jefferies, Sarah, Jackson, Alan, Stewart, Willie, Lindner, Juha, Kutscher, Sarah, Hilf, Norbert, McGuigan, Lesley, Peters, Jane, Hill, Karen, Schoor, Oliver, Singh-Jasuja, Harpreet, Halford, Sarah E, Ritchie, James W A

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CCR7-dependent trafficking of RORγ+ ILCs creates a unique microenvironment within mucosal draining lymph nodes von Mackley, Emma C., Houston, Stephanie, Marriott, Clare L., Halford, Emily E., Lucas, Beth, Cerovic, Vuk, Filbey, Kara J., Maizels, Rick M., Hepworth, Matthew R., Sonnenberg, Gregory F., Milling, Simon, Withers, David R.

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novel mechanism for the scission of double-stranded DNA: BfiI cuts both 3'-5' and 5'-3' strands by rotating a single active site von Sasnauskas, Giedrius, Zakrys, Linas, Zaremba, Mindaugas, Cosstick, Richard, Gaynor, James W, Halford, Stephen E, Siksnys, Virginijus

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The application of the fast, multi-hit, pixel imaging mass spectrometry sensor to spatial imaging mass spectrometry von Brouard, M., Halford, E., Lauer, A., Slater, C. S., Winter, B., Yuen, W. H., John, J. J., Hill, L., Nomerotski, A., Clark, A., Crooks, J., Sedgwick, I., Turchetta, R., Lee, J. W. L., Vallance, C., Wilman, E.

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Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands von Sanders, Kelly L, Catto, Lucy E, Bellamy, Stuart R.W, Halford, Stephen E

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Many Type IIs Restriction Endonucleases Interact with Two Recognition Sites before Cleaving DNA von Bath, Abigail J., Milsom, Susan E., Gormley, Niall A., Halford, Stephen E.

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One- and three-dimensional pathways for proteins to reach specific DNA sites von Stanford, Neil P., Szczelkun, Mark D., Marko, John F., Halford, Stephen E.

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PImMS, a fast event-triggered monolithic pixel detector with storage of multiple timestamps von John, J J, Brouard, M, Clark, A, Crooks, J, Halford, E, Hill, L, Lee, J W L, Nomerotski, A, Pisarczyk, R, Sedgwick, I, Slater, C S, Turchetta, R, Vallance, C, Wilman, E, Winter, B, Yuen, W H

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Dissecting protein-induced DNA looping dynamics in real time von Laurens, Niels, Bellamy, Stuart R.W, Harms, August F, Kovacheva, Yana S, Halford, Stephen E, Wuite, Gijs J.L

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How the BfiI Restriction Enzyme Uses One Active Site to Cut Two DNA Strands von Sasnauskas, Giedrius, Halford, Stephen E., Siksnys, Virginijus

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Germline Mutations but Not Somatic Changes at the MYH Locus Contribute to the Pathogenesis of Unselected Colorectal Cancers von Halford, Sarah E.R., Rowan, Andrew J., Lipton, Lara, Sieber, Oliver M., Pack, Kevin, Thomas, Huw J.W., Hodgson, Shirley V., Bodmer, Walter F., Tomlinson, Ian P.M.

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Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway von LIPTON, Lara, HALFORD, Sarah E, HODGSON, Shirley V, AALTONEN, Lauri A, THOMAS, Huw J. W, TOMLINSON, Ian P. M, JOHNSON, Victoria, NOVELLI, Marco R, JONES, Angela, CUMMINGS, Carole, BARCLAY, Ella, SIEBER, Oliver, SADAT, Amir, BISGAARD, Marie-Luise

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