Schweinfurthin natural products induce regression of murine melanoma and pair with anti-PD-1 therapy to facilitate durable tumor immunity von Kokolus, Kathleen M., Haley, Jeremy S., Koubek, Emily J., Gowda, Raghavendra, Dinavahi, Saketh S., Sharma, Arati, Claxton, David F., Helm, Klaus F., Drabick, Joseph J., Robertson, Gavin P., Neighbors, Jeffrey D., Hohl, Raymond J., Schell, Todd D.

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Genome-first approach of the prevalence and cancer phenotypes of pathogenic or likely pathogenic germline TP53 variants von de Andrade, Kelvin C., Strande, Natasha T., Kim, Jung, Haley, Jeremy S., Hatton, Jessica N., Frone, Megan N., Khincha, Payal P., Thone, Gretchen M., Mirshahi, Uyenlinh L., Schneider, Cynthia, Desai, Heena, Dove, James T., Smelser, Diane T., Levine, Arnold J., Maxwell, Kara N., Stewart, Douglas R., Carey, David J., Savage, Sharon A.

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Estimated Prevalence and Clinical Manifestations of UBA1 Variants Associated With VEXAS Syndrome in a Clinical Population von Beck, David B, Bodian, Dale L, Shah, Vandan, Mirshahi, Uyenlinh L, Kim, Jung, Ding, Yi, Magaziner, Samuel J, Strande, Natasha T, Cantor, Anna, Haley, Jeremy S, Cook, Adam, Hill, Wesley, Schwartz, Alan L, Grayson, Peter C, Ferrada, Marcela A, Kastner, Daniel L, Carey, David J, Stewart, Douglas R

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Genome-first determination of the prevalence and penetrance of eight germline myeloid malignancy predisposition genes: a study of two population-based cohorts von Hendricks, Rachel M., Kim, Jung, Haley, Jeremy S., Ramos, Mark Louie, Mirshahi, Uyenlinh L., Carey, David J., Stewart, Douglas R., McReynolds, Lisa J.

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Dose‐dependent effect of aerobic exercise on inflammatory biomarkers in a randomized controlled trial of women at high risk of breast cancer von Haley, Jeremy S., Hibler, Elizabeth A., Zhou, Shouhao, Schmitz, Kathryn H., Sturgeon, Kathleen M.

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A Genome-Wide Association Study and Rare Variant Analysis for Dupuytren Disease in a North American Population von Grandizio, Louis C., Smelser, Diane T., Haley, Jeremy S., Delma, Stephanie, Klena, Joel C., Carey, David J.

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Most Fanconi anemia heterozygotes are not at increased cancer risk: A genome-first DiscovEHR cohort population study von Deng, Joseph, Altintas, Burak, Haley, Jeremy S., Kim, Jung, Ramos, Mark, Carey, David J., Stewart, Douglas R., McReynolds, Lisa J.

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Randomized controlled trial of oral glutathione supplementation on body stores of glutathione von Richie, John P., Jr, Nichenametla, Sailendra, Neidig, Wanda, Calcagnotto, Ana, Haley, Jeremy S, Schell, Todd D, Muscat, Joshua E

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Estimated Prevalence, Tumor Spectrum, and Neurofibromatosis Type 1–Like Phenotype of CDKN2A-Related Melanoma-Astrocytoma Syndrome von Sargen, Michael R, Kim, Jung, Potjer, Thomas P, Velthuizen, Mary E, Martir-Negron, Arelis E, Odia, Yazmin, Helgadottir, Hildur, Hatton, Jessica N, Haley, Jeremy S, Thone, Gretchen, Widemann, Brigitte C, Gross, Andrea M, Yohe, Marielle E, Kaplan, Rosandra N, Shern, Jack F, Sundby, R. Taylor, Astiazaran-Symonds, Esteban, Yang, Xiaohong R, Carey, David J, Tucker, Margaret A, Stewart, Douglas R, Goldstein, Alisa M

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A Genome-First Approach to Estimate Prevalence of Germline Pathogenic Variants and Risk of Pancreatic Cancer in Select Cancer Susceptibility Genes von Astiazaran-Symonds, Esteban, Kim, Jung, Haley, Jeremy S, Kim, Sun Young, Rao, H Shanker, Genetics Center, Regeneron, Carey, David J, Stewart, Douglas R, Goldstein, Alisa M

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Association of varicose veins with rare protein-truncating variants in PIEZO1 identified by exome sequencing of a large clinical population von Smelser, Diane T., Haley, Jeremy S., Ryer, Evan J., Elmore, James R., Cook, Adam M., Carey, David J.

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Genetic Basis of Thoracic Aortic Aneurysms in a Large Unselected Clinical Population von Mirshahi, Hannah S., Haley, Jeremy S., Smelser, Diane T., Ryer, Evan J., Elmore, James R., Carey, David J.

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Durable complete responses off all treatment in patients with metastatic malignant melanoma after sequential immunotherapy followed by a finite course of BRAF inhibitor therapy von Wyluda, Edward J, Cheng, Jihua, Schell, Todd D, Haley, Jeremy S, Mallon, Carol, Neves, Rogerio I, Robertson, Gavin, Sivik, Jeffrey, Mackley, Heath, Talamo, Giampaolo, Drabick, Joseph J

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A Genome-First Approach to Characterize DICER1 Pathogenic Variant Prevalence, Penetrance, and Phenotype von Mirshahi, Uyenlinh L., Kim, Jung, Best, Ana F., Chen, Zongming E., Hu, Ying, Haley, Jeremy S., Golden, Alicia, Stahl, Richard, Manickam, Kandamurugu, Carr, Ann G., Harney, Laura A., Field, Amanda, Hatton, Jessica, Schultz, Kris Ann P., Bauer, Andrew J., Hill, D. Ashley, Rosenberg, Philip S., Murray, Michael F., Carey, David J., Stewart, Douglas R.

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Abstract 564: Genetic Basis Of Thoracic Aortic Aneurysms In A Large Unselected Clinical Population von Mirshahi, Hannah S, Haley, Jeremy S, Smelser, Diane T, Ryer, Evan J, Elmore, James R, Carey, David J

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Why Do CD8+ T Cells become Indifferent to Tumors: A Dynamic Modeling Approach von Campbell, Colin, Zhang, Ranran, Haley, Jeremy S, Liu, Xin, Loughran, Thomas, Schell, Todd D, Albert, Réka, Thakar, Juilee

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47: A DIVERTICULAR DISEASE PREDICTION MODEL USING A POLYGENIC RISK SCORE von Schaeffer, Henry D., Smelser, Diane T., Rao, H. Shanker, Haley, Jeremy S., Long, Kevin, Slipak, Sasha, Carey, David, Hoffman, Rebecca

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Molecular Characterisation of Novel Klotho Variants Identified in Patients with Ca2+ Disturbances: FR-PO293 von Grigore, Teodora, Bayliss, Asha, Stevenson, Mark, Zuidscherwoude, Malou, Carey, David J., Haley, Jeremy S., Smelser, Diane T., Olauson, Hannes, Hoenderop, Joost, Thakker, Rajesh V.

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Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function von Sinha, R, Sinha, I, Calcagnotto, A, Trushin, N, Haley, J S, Schell, T D, Richie, J P

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Increasing strength of antigenic stimulation negatively impacts memory CD8 T cell formation and function during persistent viral infection von Maru, Saumya, Haley, Jeremy S, Schell, Todd D, Lukacher, Aron

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