Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors von Holt, Melissa C, Assar, Zahra, Beheshti Zavareh, Reza, Lin, Lin, Anglin, Justin, Mashadova, Oksana, Haldar, Daniel, Mullarky, Edouard, Kremer, Daniel M, Cantley, Lewis C, Kimmelman, Alec C, Stein, Adam J, Lairson, Luke L, Lyssiotis, Costas A

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Discovery and optimization of aspartate aminotransferase 1 inhibitors to target redox balance in pancreatic ductal adenocarcinoma von Anglin, Justin, Zavareh, Reza Beheshti, Sander, Philipp N., Haldar, Daniel, Mullarky, Edouard, Cantley, Lewis C., Kimmelman, Alec C., Lyssiotis, Costas A., Lairson, Luke L.

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Abstract IA013: Intercepting pancreatic cancer development with mutant KRAS-targeted immunotherapy von Zaidi, Neeha, Huff, Amanda, Marcisak-Davis, Emily, Haldar, Daniel, Heumann, Thatcher, Konig, Max, Mog, Brian, Montagne, Janelle, Longway, Gabriella, Andaloori, Lalitya, Lyman, Melissa, Danilova, Ludmila, Nauroth, Julie, Kagohara, Luciane, Fertig, Elana, Azad, Nilo, Jaffee, Elizabeth

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A phase I study of a mutant KRAS-targeted long peptide vaccine combined with ipilimumab/nivolumab in resected pancreatic cancer and MMR-proficient metastatic colorectal cancer von Haldar, Saurav Daniel, Heumann, Thatcher Ross, Berg, Maureen, Ferguson, Anna, Lim, Su Jin, Wang, Hao, Nauroth, Julie, Laheru, Dan, Jaffee, Elizabeth M., Azad, Nilofer Saba, Zaidi, Neeha

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Abstract 2873: Evolution of immune cell composition and functionality as pancreatic intraepithelial neoplasia progresses to pancreatic ductal adenocarcinoma von Lyman, Melissa R., Mitchell, Jacob T., Kagohara, Luciane T., Barrett, Benjamin, Huff, Amanda, Shin, Sarah, Longway, Gabriella, Gupta, Anuj, Andaloori, Lalitya, Armstrong, Todd D., Haldar, Daniel, Anders, Robert, Thompson, Elizabeth, Azad, Nilo, Ho, Won Jin, Jaffee, Elizabeth, Fertig, Elana J., Zaidi, Neeha

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A phase I study of a mutant KRAS-targeted long peptide vaccine in patients at high risk of developing pancreatic cancer von Haldar, Saurav Daniel, Judkins, Carol, Ferguson, Anna, Abou Diwan, Elizabeth, Lim, Su Jin, Wang, Hao, Nauroth, Julie, Goggins, Michael, Laheru, Dan, Jaffee, Elizabeth M., Azad, Nilofer Saba, Zaidi, Neeha

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Investigating the Molecular Mechanisms of Action of Lenalidomide and Other Immunomodulatory Derivatives von Haldar, Saurav Daniel

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Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPS von Pilla, Danielle M., Hagar, Jon A., Haldar, Arun K., Mason, Ashley K., Degrandi, Daniel, Pfeffer, Klaus, Ernst, Robert K., Yamamoto, Masahiro, Miao, Edward A., Coers, Jörn

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The platelet receptor CLEC-2 blocks neutrophil mediated hepatic recovery in acetaminophen induced acute liver failure von Chauhan, Abhishek, Sheriff, Lozan, Hussain, Mohammed T., Webb, Gwilym J., Patten, Daniel A., Shepherd, Emma L., Shaw, Robert, Weston, Christopher J., Haldar, Debashis, Bourke, Samuel, Bhandari, Rajan, Watson, Stephanie, Adams, David H., Watson, Steve P., Lalor, Patricia F.

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Protein folding modulates the chemical reactivity of a Gram-positive adhesin von Alonso-Caballero, Alvaro, Echelman, Daniel J., Tapia-Rojo, Rafael, Haldar, Shubhasis, Eckels, Edward C., Fernandez, Julio M.

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Wave‐LORAKS: Combining wave encoding with structured low‐rank matrix modeling for more highly accelerated 3D imaging von Kim, Tae Hyung, Bilgic, Berkin, Polak, Daniel, Setsompop, Kawin, Haldar, Justin P.

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Neutrophils promote tumor resistance to radiation therapy von Wisdom, Amy J., Hong, Cierra S., Lin, Alexander J., Xiang, Yu, Cooper, Daniel E., Zhang, Jin, Xu, Eric S., Kuo, Hsuan-Cheng, Mowery, Yvonne M., Carpenter, David J., Kadakia, Kushal T., Himes, Jonathon E., Luo, Lixia, Ma, Yan, Williams, Nerissa, Cardona, Diana M., Haldar, Malay, Diao, Yarui, Markovina, Stephanie, Schwarz, Julie K., Kirsch, David G.

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Coupling a Mobile Hole to an Antiferromagnetic Spin Background: Transient Dynamics of a Magnetic Polaron von Ji, Geoffrey, Xu, Muqing, Kendrick, Lev Haldar, Chiu, Christie S., Brüggenjürgen, Justus C., Greif, Daniel, Bohrdt, Annabelle, Grusdt, Fabian, Demler, Eugene, Lebrat, Martin, Greiner, Markus

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Targeting transcription in heart failure via CDK7/12/13 inhibition von Hsu, Austin, Duan, Qiming, Day, Daniel S., Luo, Xin, McMahon, Sarah, Huang, Yu, Feldman, Zachary B., Jiang, Zhen, Zhang, Tinghu, Liang, Yanke, Alexanian, Michael, Padmanabhan, Arun, Brown, Jonathan D., Lin, Charles Y., Gray, Nathanael S., Young, Richard A., Bruneau, Benoit G., Haldar, Saptarsi M.

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Prevalence of hypertension among adolescents (10-19 years) in India: A systematic review and meta-analysis of cross-sectional studies von Daniel, Roy Arokiam, Haldar, Partha, Prasad, Manya, Kant, Shashi, Krishnan, Anand, Gupta, Sanjeev Kumar, Kumar, Rakesh, Choukem, Simeon-Pierre

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Single breath-hold CINE imaging with combined simultaneous multislice and region-optimized virtual coils von Kim, Daeun, Coll-Font, Jaume, Lobos, Rodrigo A, Stäb, Daniel, Pang, Jianing, Foster, Anna, Garrett, Thomas, Bi, Xiaoming, Speier, Peter, Haldar, Justin P, Nguyen, Christopher

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Quantifying exchange forces of a spin spiral on the atomic scale von Hauptmann, Nadine, Haldar, Soumyajyoti, Hung, Tzu-Chao, Jolie, Wouter, Gutzeit, Mara, Wegner, Daniel, Heinze, Stefan, Khajetoorians, Alexander A.

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SGLT2 Inhibitors Act Independently of SGLT2 to Confer Benefit for HFrEF in Mice von Berger, Justin H, Matsuura, Timothy R, Bowman, Caitlyn E, Taing, Renee, Patel, Jiten, Lai, Ling, Leone, Teresa C, Reagan, Jeffrey D, Haldar, Saptarsi M, Arany, Zoltan, Kelly, Daniel P

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Dynamics of photoexcited 5-bromouracil and 5-bromo-2′-deoxyuridine studied by extreme ultraviolet time-resolved photoelectron spectroscopy in liquid flat jets von Kang, Do Hyung, Koga, Masafumi, Haldar, Neal, Neumark, Daniel M

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Socio-demographic heterogeneity in the prevalence of COVID-19 during lockdown is associated with ethnicity and household size: Results from an observational cohort study von Martin, Christopher A., Jenkins, David R., Minhas, Jatinder S., Gray, Laura J., Tang, Julian, Williams, Caroline, Sze, Shirley, Pan, Daniel, Jones, William, Verma, Raman, Knapp, Scott, Major, Rupert, Davies, Melanie, Brunskill, Nigel, Wiselka, Martin, Brightling, Chris, Khunti, Kamlesh, Haldar, Pranab, Pareek, Manish

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