RAC1 and Melanoma von Halaban, Ruth, PhD

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Early B cell changes predict autoimmunity following combination immune checkpoint blockade von Das, Rituparna, Bar, Noffar, Ferreira, Michelle, Newman, Aaron M, Zhang, Lin, Bailur, Jithendra Kini, Bacchiocchi, Antonella, Kluger, Harriet, Wei, Wei, Halaban, Ruth, Sznol, Mario, Dhodapkar, Madhav V, Dhodapkar, Kavita M

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Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure von Premi, Sanjay, Wallisch, Silvia, Mano, Camila M., Weiner, Adam B., Bacchiocchi, Antonella, Wakamatsu, Kazumasa, Bechara, Etelvino J. H., Halaban, Ruth, Douki, Thierry, Brash, Douglas E.

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Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas von Krauthammer, Michael, Kong, Yong, Bacchiocchi, Antonella, Evans, Perry, Pornputtapong, Natapol, Wu, Cen, McCusker, Jamie P, Ma, Shuangge, Cheng, Elaine, Straub, Robert, Serin, Merdan, Bosenberg, Marcus, Ariyan, Stephan, Narayan, Deepak, Sznol, Mario, Kluger, Harriet M, Mane, Shrikant, Schlessinger, Joseph, Lifton, Richard P, Halaban, Ruth

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GNA14 Somatic Mutation Causes Congenital and Sporadic Vascular Tumors by MAPK Activation von Lim, Young H., Bacchiocchi, Antonella, Qiu, Jingyao, Straub, Robert, Bruckner, Anna, Bercovitch, Lionel, Narayan, Deepak, McNiff, Jennifer, Ko, Christine, Robinson-Bostom, Leslie, Antaya, Richard, Halaban, Ruth, Choate, Keith A.

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In Vivo Identification of Tumor- Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of Melanoma von Karreth, Florian A., Tay, Yvonne, Perna, Daniele, Ala, Ugo, Tan, Shen Mynn, Rust, Alistair G., DeNicola, Gina, Webster, Kaitlyn A., Weiss, Dror, Perez-Mancera, Pedro A., Krauthammer, Michael, Halaban, Ruth, Provero, Paolo, Adams, David J., Tuveson, David A., Pandolfi, Pier Paolo

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Germline MC1R status influences somatic mutation burden in melanoma von Robles-Espinoza, Carla Daniela, Roberts, Nicola D., Chen, Shuyang, Leacy, Finbarr P., Alexandrov, Ludmil B., Pornputtapong, Natapol, Halaban, Ruth, Krauthammer, Michael, Cui, Rutao, Timothy Bishop, D., Adams, David J.

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Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11.21 to metastasis von Farshidfar, Farshad, Rhrissorrakrai, Kahn, Levovitz, Chaya, Peng, Cong, Knight, James, Bacchiocchi, Antonella, Su, Juan, Yin, Mingzhu, Sznol, Mario, Ariyan, Stephan, Clune, James, Olino, Kelly, Parida, Laxmi, Nikolaus, Joerg, Zhang, Meiling, Zhao, Shuang, Wang, Yan, Huang, Gang, Wan, Miaojian, Li, Xianan, Cao, Jian, Yan, Qin, Chen, Xiang, Newman, Aaron M., Halaban, Ruth

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Integrated NY-ESO-1 antibody and CD8+ T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab von Yuan, Jianda, Adamow, Matthew, Ginsberg, Brian A, Rasalan, Teresa S, Ritter, Erika, Gallardo, Humilidad F, Xu, Yinyan, Pogoriler, Evelina, Terzulli, Stephanie L, Kuk, Deborah, Panageas, Katherine S, Ritter, Gerd, Sznol, Mario, Halaban, Ruth, Jungbluth, Achim A, Allison, James P, Old, Lloyd J, Wolchok, Jedd D, Gnjatic, Sacha

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Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5 von Chen, Yanran, Su, Haomiao, Zhao, Jianing, Na, Zhenkun, Jiang, Kevin, Bacchiocchi, Antonella, Loh, Ken H., Halaban, Ruth, Wang, Zhentian, Cao, Xiongwen, Slavoff, Sarah A.

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Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032 von Rubinstein, Jill C, Sznol, Mario, Pavlick, Anna C, Ariyan, Stephan, Cheng, Elaine, Bacchiocchi, Antonella, Kluger, Harriet M, Narayan, Deepak, Halaban, Ruth

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PLEKHA5 as a Biomarker and Potential Mediator of Melanoma Brain Metastasis von Jilaveanu, Lucia B, Parisi, Fabio, Barr, Meaghan L, Zito, Christopher R, Cruz-Munoz, William, Kerbel, Robert S, Rimm, David L, Bosenberg, Marcus W, Halaban, Ruth, Kluger, Yuval, Kluger, Harriet M

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Genome-wide screen of promoter methylation identifies novel markers in melanoma von Koga, Yasuo, Pelizzola, Mattia, Cheng, Elaine, Krauthammer, Michael, Sznol, Mario, Ariyan, Stephan, Narayan, Deepak, Molinaro, Annette M, Halaban, Ruth, Weissman, Sherman M

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Ultra-sensitive molecular residual disease detection through whole genome sequencing with single-read error correction von Li, Xinxing, Liu, Tao, Bacchiocchi, Antonella, Li, Mengxing, Cheng, Wen, Wittkop, Tobias, Mendez, Fernando L, Wang, Yingyu, Tang, Paul, Yao, Qianqian, Bosenberg, Marcus W, Sznol, Mario, Yan, Qin, Faham, Malek, Weng, Li, Halaban, Ruth, Jin, Hai, Hu, Zhiqian

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Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate von Ha, Byung Hak, Davis, Matthew J, Chen, Catherine, Lou, Hua Jane, Gao, Jia, Zhang, Rong, Krauthammer, Michael, Halaban, Ruth, Schlessinger, Joseph, Turk, Benjamin E, Boggon, Titus J

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PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets von Scortegagna, Marzia, Lau, Eric, Zhang, Tongwu, Feng, Yongmei, Sereduk, Chris, Yin, Hongwei, De, Surya K, Meeth, Katrina, Platt, James T, Langdon, Casey G, Halaban, Ruth, Pellecchia, Maurizio, Davies, Michael A, Brown, Kevin, Stern, David F, Bosenberg, Marcus, Ronai, Ze'ev A

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MEDME: an experimental and analytical methodology for the estimation of DNA methylation levels based on microarray derived MeDIP-enrichment von Pelizzola, Mattia, Koga, Yasuo, Urban, Alexander Eckehart, Krauthammer, Michael, Weissman, Sherman, Halaban, Ruth, Molinaro, Annette M

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Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas von HOEK, Keith, RIMM, David L, WU, Terence, NIINOBE, Michio, YOSHIKAWA, Kazuaki, HANNIGAN, Gregory E, HALABAN, Ruth, WILLIAMS, Kenneth R, HONGYU ZHAO, ARIYAN, Stephan, AIPING LIN, KLUGER, Harriet M, BERGER, Aaron J, CHENG, Elaine, TROMBETTA, E. Sergio

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MicroRNA signatures differentiate melanoma subtypes von Chan, Elcie, Patel, Rajeshvari, Nallur, Sunitha, Ratner, Elena, Bacchiocchi, Antonella, Hoyt, Kathleen, Szpakowski, Sebastian, Godshalk, Sirie, Ariyan, Stephan, Sznol, Mario, Halaban, Ruth, Krauthammer, Michael, Tuck, David, Slack, Frank J., Weidhaas, Joanne Barnes

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Author Correction: Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11.21 to metastasis von Farshidfar, Farshad, Rhrissorrakrai, Kahn, Levovitz, Chaya, Peng, Cong, Knight, James, Bacchiocchi, Antonella, Su, Juan, Yin, Mingzhu, Sznol, Mario, Ariyan, Stephan, Clune, James, Olino, Kelly, Parida, Laxmi, Nikolaus, Joerg, Zhang, Meiling, Zhao, Shuang, Wang, Yan, Huang, Gang, Wan, Miaojian, Li, Xianan, Cao, Jian, Yan, Qin, Chen, Xiang, Newman, Aaron M., Halaban, Ruth

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